Making a Hypnotic Sedative from Acetone
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- Опубликовано: 27 сен 2024
- In this video I make an old hypnotic anesthetic agent called chlorobutanol from acetone, bleach, and potassium hydroxide.
Note that this chemical is NOT a recreational drug, and I have yet to find any examples of someone ever trying to use it as such. This was used nearly exclusively as a medical anesthetic until its use was discontinued due to its major side-effects which I discuss later in the video.
As always, do not attempt anything you see except under professional guidance.
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#chemistry #science #hydrogen #gas #elements #fire #chemical #industury #color
Feeling crossed for a month sounds like absolute hell on earth
Yeah sounds like the worst torture possible. Tbh this chemical got scarier and scarier the more I read about it
Some people looking to not be in this reality would find its extended action a positive, but the hat man will not have that 🎉
It doesn't work like that with super long acting benzos or phenobarbital. The high is still like 20 hours, and yes with phenobarbital it's half life is like 20 days, you are not feeling the phenobarbital for 20 days more like 10 to 12 hours yet you will test postive for weeks after it wears off.
Oh, yes, this is the longest acting substance, ever heard! 😮
Speak for yourself. My life be like ooooowah oowah
This has given the confidence to go on dates again thank you !
Narrator: all these hydrogens are replaced with chlorine.
Graphics: bromine, everywhere.
Audience: let’s make chloroform jokes.
Lol honestly that is my bad 😅 I should have made my own graphics with chlorine instead of bromine but the ones I found looks so clean I couldn't help it
That's shamefully inconsiderate,@@integral_chemistry
The half-life is long because it's a tertiary alcohol, which cannot be readily oxidized like chloral, or trichloroethanol, or ethanol.
Yeah thats what I figured. I honestly am not sure if your body can even oxidize it at all, I think I read somewhere that it is metabolized by glucuronidation or sulphation, and then eliminated renally.
@@integral_chemistry I wonder if it could worsen liver or kidney function if there is already a reduced function of those organs. With its half life, I wonder if it could cause a stead and long term decrease in renal function for someone that has CKD and does not know it.
@@user-nu8in3ey8cif it’s that hydrophobic, probably not. Kidneys typically filter out H2O soluble compounds, that’s why the CYP enzymes and glucoronidation exists. I bet there is some reactive intermediate from depletion of glutathione from glucoronidation pathway saturation.
@@isaackimball6716 That sounds reasonable.
A 37 day half life sounds like severe and unending side effects.
ODing on this seems like an alchemical trial a necromancer would do before getting to the next level
LMAO love it! I unironically want to work jokes like this into my videos someday I think all the old alchemy stuff is really funny
@@integral_chemistry like if the witcher was an INT only class
even taking it as a drug would NOT be fun you don't get "high"
@@Aaron-zu3xn it would put you in a state of feeling dead for a month and change which sounds like something a necromancer would do to get close enough to the other side to talk to it lol
There's a paper out there that even describes terminal self-harm from ingesting mouthwash that contained chlorobutanol. Whether or not the incident was concomitant with other ingested substances due to the past behavior of the poor soul could be debated but it isn't seen as an anti-fungal, antibacterial additive in personal care products anymore.
Excuse me, does this cloth smell like chlorobutanol?
very clever Jimmy Carr reference +1
😂🤣😂
Why yes! Yes it does in fact smell of chlorobutanol! Might I have another whiff?
They just haven't eaten before. It's loveliness smell is too nasty to consume, but to make that joke more fun, the question would have to be, "excuse me, does this cloth smell like chloroform?"
*thump*
For anyone wondering, the effect is literally as having a flu without the pain and fever. You just get enormously letargic and dysphoric and fall asleep very easily. I imagine even hitting your head really hard is more recreational. The taste is like menthol flavoured sand.
Sounds wretched.. literally the more I hear about it, the worse it sounds
So I cant use it to hypnotize someone into robbing a bank for me? Damn XD
@@LeonardGreenpawno that’s scopolomine. Devils breath.
Which is now used as a motion sickness patch
@@SpecialistGuava interesting, do feel free to tell me more. For uh research purposes :D
Yes Ii was pouring ING swat and freezing at same time. I though I was dieing
I've made this, definitely don't try taking it since a lot of the dosage information is incorrect and it's got a half life of something like 37 DAYS. I wasn't back to normal for nearly a month, my wife still brings it up occasionally...
Good job man! 😎👍 🛋️ 😴 💤
I'm gonna take it anyway. What dosage would you reccomend? I was thinking something like 200 mg would be active yet not too overwhelming.
@@lagrangiankid378 I'd keep it under 300mg which was the medical dose for sleep and I wouldn't take it more than once a month.
@lagrangiankid378 if you aren't going to listen to the SERIOUS AND EMPHATIC warnings to not do this, I would not recommend starting with something so large as 200mg. With a halflife of over a month, you would not process out all of the chlorobutanol for 5-8 months, with 6mg remaining at 5 months and finally reducing to >1mg at 8 months.
I will not provide a suggested dosing amount as I am not a pharmacist not do I want to encourage anyone to attempt this, but anyone stupid enough to do this needs to be aware that a half-life time is the time to half the original dosage and should plan accordingly. You will be in a highly suggestive state for at least a month, you will have a bad time and you will make regrettable actions.
@@jacobbrown7367 200 mg is not that large of a dose for something with this level of psychoactivity. For comparison chloral hydrate is dosed at 500 to 1000 mg. The OP of this thread ingested a gram or so if I remeber correctly and this lead to overdosing. And (unlike you) I know precisely what the elimination half-life is (which by the way usually refers to blood levels, not to the total amount in the body). And by the way 37 days is the half-life as measured in vitro at a pH of 7.4, terminal elimination half life in vivo in healthy human subjects is reported to be only 10.3 days (C Tung et al., Biopharm Drug Dispos 1982). I have quite some free time as I'm currently taking a vacation so there's plenty of time to recover and this self experimentation won't have any significant consequence. I know what I'm doing and I'm highly prepared, experienced and equipped. I just asked some anecdotal dosage information as there is little or no human data on this obscure and very old CNS depressant.
sounds fun, let's watch this video before it gets shadow banned by youtube. Love your stuff bro keep up the good work, i know RUclips can be a cruel mistress sometimes.
this stuff smells like an artificial chemical trying to not smell like an artificial chemical
LMAO that is the best way I've heard it described
Hahahahaha
This should be on the short list of true "zombie" drugs.
Literally. There's some scary ones out there, this one is in the same area as benadryl where it's such a miserable experience they don't bother regulating it
@@integral_chemistry ever done it?
@@integral_chemistrythey'd better
Can't imagine the damage of someone unleasheing this agent on a unknowing group of people
@@bromine_35 you can do worse than this,
Some time ago i worked in a factory that (next to other stuff) made this bloody stuff in the tons range
Gave us all sorts of problems with the centrifuge and discoloration and quality control
Edit: The reason you can't find any literature about the reaction mecanism is, that the mecanism is not fully understood yet. I searched for it for the better part of a year and could only obtain some information on side products and reaction conditions
Never again but very nice video once again
Why would anyone make this stuff in the "tons range"?
@@Standing.W.Israel it is used as a preservative in cosmetics and pharmaceuticals
@@emmanueleferrarotto2986 imagine accidentally ingesting some lipstick and go to sleep for a month
You could easily further purify the chlorbutanol through sublimation. Mix it well with some calcium chloride in a beaker to further dehydrate, then heat from the bottom and crystallize on top on the exterior surface of a round bottom flask filled with ice water.
Is this a common method for recrystallizing compounds that sublimate? I’m not far along in my chem education but it seems like that would cause a bit of loss.
@michaelevans6216 as with any re-x there's always a loss.
Where do you guys learn this stuff? Genuinely curious
@@gyanjury6753 Sciencemadness forum, wikipedia and youtube obviously. Also, textbooks and college chemistry classes are also an option...
sounds like a drug given to hostages being interrogated
Tbh I doubt it would even work for that. The whole time you're drugged you're just kinda unable to speak properly or comprehend anything around you
@@integral_chemistry sweet jesus, "too toxic for Saddam." think about that.
you're thinking of sodium pentathol and it doesn't make you tell the truth you can even confess to things that never happened so it's worthless for interrogation,there was once a case where the police went looking for bodies a person claimed they buried in central park NY and there were never any bodies they just implanted the memory.
These types of hypnotic sedatives would likely render the person a deadhead and rather irritable as well similar to the first generation antihistamine like phenergan - horrible in large doses and even worse in even medium ones.
@@peter5.056 You know where the WMD's are? do tell 😂
This dude made his own tranquilizer at home way to freakin' go homie. Shit is getting deep here on RUclips.
Bro you're schizing out my NSA agent
Mines’ took three booths at the China Buffet.
You always take it a step further, I thought it would be just chloroform initially when I saw the title!👍
Btw, 1:52 the sep funnel is slowly dropping down, which is an alarming sign that accident could happen at some point.
I like to make every video a surprise that only rewards you if you actually take the time to watch to the end. I think its fun and a nice little way to foster continued interest (jury is still out on whether it'll work lol)
And yeah I actually noticed the same thing.. I think its a "settling" due to the weight of such a large sep funnel on such a tiny ring stand. I did leave it overnight once or twice and it never failed, but it is still not ideal by any means.
Think I'll probably bolt some bars to the inside of my fume hood for greater flexibility but also to support some of these heavier objects.
@@integral_chemistry I made a custom-made lattice inside my fume hood just to accommodate different clamps, I find setting up the clamp and stand every time quite annoying, stands are also prone to tip over which I am not a big fan of.
@DangerousLab thats exactly what I want to do, honestly I might have gotten the idea from one of your videos. Where did you source the metal bars you used for the scaffold?
@@integral_chemistry I didn't use metal bars, those are carbon fiber rods I got from Aliexpress, and the interconnection is made out of PP.
@@integral_chemistry Those are not metal bars, they are carbon fiber rods I got from Aliexpress, and the interconnections are made out of PP.
Whoah, loved to see a haloform reaction taken into practice!!! This is such a scary chemical... You have great video ideas!!
Thank you so much! The haloform reaction is super cool, been trying to think of ways to implement it lately.. maybe iodoform next?
I have been a subscriber for several months now and I find your video teaching to be hypnotic. Your intellect and education in chemistry is terrifying to me. Obviously, I know very little about chemistry and synthesis. I know you use your education for good and not evil. It's very easy to see how someone with your background could make things horrible for a lot of society in a very short time. I am in awe of your education and I am thankful for people like you.
Peace
Thank you so very much, that mans a lot. I worry often that the pace I go through topics is maybe too fast to the point of being confusing so I love hearing that is "hypnotic" because in a way that's what I'm going for. I love chemistry, and I get so entranced in the process that it sort of becomes this mesmerizing experience where nothing else exists for a little while. I try to channel this vibe through the very focused way I edit down the videos, which I'm very happy to hear you appreciate.
I also love hearing about your interest in chemistry! Its a subject most people dislike in my experience, so its refreshing to hear people appreciate the wonder of it all.
The pace is great I wish I would have paid more attention in high school. 40 year pipefitter, no chemistry but, always did love it and was intrigued by it. I have a newfound interest in primer recharging which has fueled the desire to learn some simple synthesis for a few different labs that I will need. I'm in process of gathering equipment now.
I have some really good chemists to lean on and ask questions to through a couple different groups. You guys are all top notch!
Thanks again for the knowledge keep up the great work
@@magua1368have you seen the videos on nickel hydrazine nitrate? It looks like it would be a decent component of a primer composition.
Chemistry is one of those fields that really weed out the "ill-doers" believe it or not, the mad scientist that media portrays is a stock fiction character and nothing else. People with unmotivated malignant intent are usually addled by extreme emotion and are usually not the types to go through academic or technical education. The worst harm happens by accident, or gross negligence by administrative authorities. This is why you see most instances of mass violence committed with guns or garden variety explosive devices, and rarely with chemical, biological or radiological weapons. Media loves portraying violent anti-social types "the psychopath" as these smart, coldly calculating geniuses that hold dark secret knowledge that they apply flawlessly in the execution of sick fantasy or whatever, but real life criminally insane perps usually have very low cognitive capacity. The more intelligent ones are rarely found in violent crime or terrorism, but are the ones in business making life as a worker in corporate hell. The fear of the knowledgeable/literate dates back to early medieval times and has sadly been deeply embedded in our culture, people fear computer literates too, and respect their mechanic about as much as their dentist.
Just had to point that out, dont fear the knower, the knower is likely why you survived childhood and enjoy a relatively peaceful existence :)
@@magua1368 get into it
be careful
have fun
start small
thats all you gotta start with to have a sometimes nice and at other times annoying hobby
peace
I liked and subscribed for more dope chemistry dude! 10 minute's and you somehow managed to explain like everything and anything i couldve wanted to know
So I tried this back in 2017. I ate some, and despite its flavor, didn't puke. It was like plastic cloves amd didn't knock me out at all. It was a waste of chloroform, albeit the science was cool. You did it way better than myself, and you were right to not eat it. Think headache ❤
Considering how readily available the chemistry is id would not be surprised that this is actively used in bioweapon attacks, dirty little tricks indeed.
Thas chem. Bio would be flinging plague rats.
is someone gonna tell this guy about TATP?
@@PetkesPaintings that's not a bioweapon that's just homemade explosives
I've made chlorobutanol from chloroform and acetone. It smells really nice.
Right? Super unique and pleasant smell (at least at first)
A month of hypnotic suggestability?
Sounds like the perfect compound for psychic driving.
I love this video. I enjoy how your videos go step by step and not too many technical terms. Would you consider doing a video on SLU PP 332 in a pill form instead of as an injection?
This was my first home synthesis, it’s a classic
Honestly I'm shocked it took me so long to get around to this one. Very straightforward and satisfying. I'm a big fan of any organic reaction where the products have vastly different properties than the reagents (especially a vastly different smell)
@@integral_chemistry that’s how I knew I succeeded was the smell. Ofc the chcl3 I used was made from pool bleach and was not distilled before using it for 2nd step. Sample prolly had sodium acetate and KOH impurities even tho I tried to remove KOH via filtration. Chlorobutanol is hard to store it likes to sublimate on the lid of the jar I put it in.
Very essential video for knowing about the good stuff! 👍
I prefer Ambien, Lunesta, Sonata. Benzos make you chill too. 😎
lol yeah tbh I'd prefer almost any other sedative to this stuff, seems like a real bad time compared to some of those others.
@@integral_chemistry Midazolam IV in the ER was top notch! 😱😂
even phenazepam would be better than this shit. great video nonetheless
I understood like, 4 words in this video, but I enjoyed my time here.
I’m sure acetone on its own could be a sedative just based on how nasty it smells. It might end up being a one time use kind of thing but I don’t know. I’m not a chemist.
Idk how accurate this is but I´ve heard that Adolf Von Baeyer synthesized barbituric acid from human urine and apple juice, to make sodium thiopental? Maybe this is something you could try and make a video about. Definitely gives the opportunity for some good video titles; "Making anesthesia from apple juice and pee" 😂
Huh I've never heard of that before but definitely worth looking into. I know you can make barbituric acid from malonic acid (which does occur in apples) and urea (which is definitely in pee lol). I'll have to check it out and see if its feasible
For anybody that doesnt understand: never make and NEVER USE THIS STUFF.
THE "HIGH" WILL LAST FOR A MONTH MINIMUM.
I wonder if ethanol could be used instead of acetone.
As a reagent one spatula tip of magneson I/azo violet in 100 ml of diluted sodium hydroxide solution is sufficient.
Hm so maybe I wasn't using too much.. this stuff is just STRONGLY pigmented.
As a side note I made para red as well and I want to try using it as a fabric dye, but I read that in order for the dye to be permanent it needs to be coupled with phenol or aniline. You know anything about this?
@@integral_chemistry
Yes, azo violet is a fairly rich dye.
The reference to phenols and amines refers to the coupling process itself and does not indicate an additional work step for fixation.
I have to admit that the last time I dealt with textile dyeing was in my senior year - that was over 30 years ago.
So here is a translated text from one of my school encyclopedias at the time:
Developmental coloration: In contrast to direct dyes, developing dyes are created on the fiber. They are often azo dyes. Two components are required for their production, namely an aromatic as a coupling component and an aromatic diazonium salt. The coupling component is dissolved in a basic, aqueous medium. The fibers, which are mostly cellulose fibers, are soaked with it and then dried. They are then treated with the diazonium salt solution. The coupling reaction that creates the dye therefore takes place on the fiber. Like the vat dyes, the developing dyes are not water-soluble and therefore very wash-fast. Naphtol AS (3-hydroxy-2-naphthoic acid anilide), a derivative of naphthalene, is often used as the coupling component, which is why it is also referred to as naphtol-AS dyes.
For your coloring with para-red this means that diazotized 4-nitroaniline and β-naphthol would have to be coupled directly on the textile.
@@integral_chemistry
The mention of phenols and amines does not mean an additional work step, but rather the well-known coupling reaction itself, which must take place directly on the textile and thus leads to a wash-fast color.
For your coloring with para-red this means that diazotized 4-nitroaniline and β-naphthol would have to be coupled directly on the textile.
@experimental_chemistry oh really? Huh so I'm guessing two different dilute baths? Does order matter?
@@integral_chemistry
The concentration of the developer solutions influences the color depth of the dyed textile.
Here are instructions for dyeing with Para-Red: Solution A: 10 ml diluted sodium hydroxide solution, a little beta-naphthol. The dyed material is immersed in the solution. Solution B: 25 ml water, some sodium nitrite, some p-nitroaniline, 10 ml diluted sodium hydroxide solution. The solution is cooled to below 5 degrees Celsius and then 25 ml of diluted hydrochloric acid is added until it turns yellow. The dyed textile is then transferred from solution A to solution B.
Following these instructions (I dug out my notes that are over 30 years old) we dyed T-shirts in our senior year of high school chemistry class (of course the amounts of the solutions were adjusted accordingly).
The instructions are probably universally applicable. Depending on the desired dye, the phenol and aniline components can be exchanged accordingly.
This looks great, I could use a one month nap.
lmao I feel that in my bones. TBH I think I could manage a one month nap no sedative required
Can you tell us the actual effect in plain English?
Some of us have no idea what crossed is.
the metabolism of the substance occurs in the liver and the 4 carbon chain might be more fat soluble leading to longer time for total bodily elimination. Just a thought
Ooh honestly this is one of the more feasible ideas I've heard. It is unfortunate that with chemicals like this that have clearly better alternatives, nobody is ever going to really bother with clinical trials at this point and so we can really only guess at the biochemical mechanisms for such things
@@integral_chemistry went to college for pharmacology and it reminded me of other halogenated hydrocarbons beyond the basic 2 carbon structure that would be more volatile and certainly not aromatic
I was expecting this to be a synthesis of chloral hydrate. I remember hearing about 20 years ago that it's a very easy synthesis. Requiring you to just bubble chlorine gas through I think ethanol. Which sounds suspect and comes from the same source that claimed you can separate ether from hexane by mixing it with water and draining off the bottom water layer. But it's got me wondering how easy/hard the actual synthesis of chloral hydrate is. It would be a real treat if you could cover this one. If legally possible.
Hmm ill definitely look into it. I'm pretty sure legally that would be fine, lately the big concern is not getting stuff removed by youtube's AI. Lots of things like that get auto-flagged
@@integral_chemistry Awesome. I appreciate it. Hopefully RUclips's robot army leaves you alone.
Im hypnotised just looking at those crysyals 😂
So how did the date go?
With the chloroform, how could it go bad?
Exactly
I love synthesizing drugs in a sketchy manner and using the kids in my basement to test it before I try myself
😬
Ah....the old electrophllic attack trick.
Well done, but still looking forward to your azo violet video... 😉
Thanks! I did wrap up the azo violet a few weeks ago, but I've just been too busy to do the voice recording and editing. Likely have it out within the next week or so.
BTW I read that azo violet gives a color change with ammonium similar to the blue color change with magnesium. Would you happen to know anything about that?
@@integral_chemistry
No, but I will try it out and report about it.
Ammonium often is a disturbing ion in analytics, so it has to be driven out beforehand by boiling the test substance with sodium hydroxide solution.
@@integral_chemistry
Since this platform is ghosting my answering comments I have to answer via my German channel account:
Will it base-eliminate to the 1,1-dichloro, 2,2-dimethyl oxirane? Chlorines being about the same size as methyl groups...lipophilic!
Then...slowly...interesting.
Fantastic video mate.😊
Great vid mate.
Thanks man!
I love this channel
Anyone heard of Telomir 1 ❤❤❤😮❤❤❤ live forever ❤
Nice synthesis! Is pursuing the fluorine analog even possible?
I doubt it would be using this route, and I can't find any literature about it. May indeed be possible by another route, but fluoroform is really hard to work with (boils at like -80 degrees) and deprotonation wouldn't work due to the extreme electronegativity of fluorine.
Also thank you very much! I was worried people wouldn't care much for this vid
Not by this route, also the end product would act like an acid more than an alcohol because fluorine is pretty greedy for electrons. 😂
A lot of people don't know chlorine is partly bromine
Oh?
When you make large scale, buy on this experiment right laboratory glass.
Bookmarking for future reference.
An influencial German chemistry creator brought about my ban, because I dared to point out his mistakes publicly. 🙄
Feel free to ask the platform if they can reverse it. I am not overly optimistic about that.
Yeah youtube is not a particularly flexible platform.. and this guy doesn't sound very scientific. As scientists we are supposed to relish in and rely on other people out there with the knowledge to point out our mistakes. Can't imagine how boring science would be if I knew everything about everything and nobody out there knew enough to challenge me..
@@integral_chemistry
The creators on this platform are mostly not interested in scientific discourse, but rather in being soldiers of fortune and cultivating vanity. Accordingly, openness to criticism is weak. People like us, who see mistakes not as a personal flaw but as an opportunity to grow professionally, are the exception here.
@@experimental_chemistry I have noticed that to be the case unfortunately. It is to the point that I've had several commenters on here surprised by how open I've been to their critique because they've come to expect hostility and defensiveness. Its honestly quite sad considering how valuable an open discourse could be in the RUclips chemistry community..
Chemistry. Addition and Subtraction at its finest.
Addin that to my list of stuff to snort
Is it possible that the dichlorocarbene reacts to form tetrachloroethylene? That might explain why there’s still so much chloride even after completion.
That is definitely possible, honestly probable. I'm convinced there are definitely multiple side reactions going on here, not least because after the formation of the deprotonated version of the chlorobutanol, there a big chance that free oxygen just displaces a chlorine and closes in a ring with the adjacent carbon
notice you said chloroform but the picture showed bromoform
@@GH-jl2tdOnce the graphic switches to bromine as the halogen it proceeds all the way to bromoform.
Yeah my bad. Bromine is much more often used in this reaction and so the general mechanism I used shows bromine instead of chlorine.
I made a note about it on screen but it's quite small
Okay but how much potassium hydroxide did you use to form the chloroform? How long was it reacted?
I didn't add any to make the chloroform, bleach already contains a good deal of hydroxide to keep it stable over long periods of storage
NileRed seemed to think in his synthesis the cloudiness in the chlorobutanol reaction was simply finely dispersed potassium hydroxide, not potassium chloride.
Hm.. I'll have to ask him about that. Potassium hydroxide is so crazy soluble I didn't consider that a possibility, especially since it has to dissolve to react in the first place. Never know though, definitely worth looking into.
@@integral_chemistry I think it’s one of those things where, it’s not super soluble in organic solvents, but moreso, it’s driven forward by the higher solubility of the product relative to the hydroxide. Also, it would make a lot more sense as you saw in your mechanism. No formation of carbines or loss of product due to some weird side reaction. I suppose also, you could filter it, dry it out and see if it’s hygroscopic, or reacts with something like calcium to make calcium hydroxide, which wouldn’t be the case with potassium chloride.
It's either KCl or a KHCO3/K2CO3 impurity from CO2 uptake by KOH.
@@toseltreps1101 I really don’t think that could be it just by how much there is. If you look at the equation, hydroxide is regenerated, so it would make sense that’s what it is. Also, in basic medium, conversion of KOH to K2CO3 doesn’t usually happen that readily and that quickly
@toseltreps1101 also, as I stated, you could easily determine if it was potassium chloride by washing it well, drying it, redisolving it in water and adding calcium chloride. That would precipitate calcium hydroxide if it was just powdered hydroxide, but nothing would happen if it was potassium chloride.
Your first chemical synthesis breakdown showed bromine not chlorine. Just FYI.
This will calm my gimp 👌🏻
I volunteer as tribute Sir. We should link up! 😂
LD50?
Chloral Hydrate smells similar to
Cool, I'm going to go dab some bong rips of this.
I want some
I wanna learn how to make Dicyanian
Can you do ether?
Go ahead and try some. Let me know if you like it.
Can we get an Adrenochrome synthesis? I wanna make it too the next Millenia 😂
Hey apoptosis wanna join a discord server I made for science youtubers only?❤
I though you was going to make 1,4 butandiol🎉 or ghb
Lol I've considered it but those are actually commonly abused so I think that might get the video taken down pretty fast
Chemistry freaks me out.
What no trip report? Swim commented
wouldn't this half life lead to physical dependence after a single dose?
hmm thats a good question. Honestly I think this is one of those types of drugs that it isn't really possible to become physically addicted to, but if there was something that had the same effect as an amphetamine for an entire month yeah you'd probably be addicted after a single dose.
@integral_chemistry addiction=/= physical dependence. If you have sedatives constantly in your system for even a week or two (such as benzodiazepines, alcohol, sleeping pills, etc) you will have mild withdrawal after stopping. I bet if you dosed this compound you would sober up in a day or two, not because the drug cleared your system, but because your receptors downregulated to compensate for the drug. When you do actually clear the drug I bet you would feel WD after that single dose.
Am I the only one that thinks the diagram at 4:00 describing the reaction looks like one guy puking and another guy with expolsive diarrhea followed by two crosses (presumably on the graves of the previous two guys)?
Just what the heck is going on in this reaction???
How long do effects last after boofing 😬
I’m assuming this is a possible step off for 1.4bd?
1.4bd?
@@integral_chemistry 1,4-butanediol, he almost certainly means
Cool. A one month high.
Why not stop at chloroform?
Could that be used on an unsuspecting date?
I'm just asking for my friend.
Not for me for my friend.
Would my date...uh I mean my friends date know what happened afterwards?
Just asking for my friend. Not for me. Hehehe .
Could I... uh I mean my friend get in serious trouble for that?
Just asking. Hehehe 😃👋
😊
Sorry bro I came late to watch your video and I'm a new subscriber but I'm trying Comment here if not You read it up to you but if you read it I'm excited I have a question for you Apoptosis can you make Chloroacetone
You definitely want to do this reaction on ice water salt mix. It must be done in a glass container❤
Geek squad
I see bromine
Turksh translate plz
Guess a dialysis might help?
Only, how do u tell the people in the hospital what u did...
Sounds like an all-round horrible sedation.
Yeah it honestly sounds hellish..
Good
Extremely toxic to the liver
Huh reminds me of that one powder rampant in South America. Can't remember the darn spelling (scolophamine? Idk it was spelled similar to that).
Ted Bundy could have really made good use of this stuff.
.
YOU ARE TERRIBLE TO TEACH THIS. I NOW CANNOT SUBSCRIBE OR DONATE TO SOMEONE MAKING DRUGS
Just so you know (and I mean this in the kindest way) but this is not a drug in the way you are using the word. Recreational drug making is strictly not allowed on RUclips and not something I will ever consider doing.
This is a hypnotic agent. It had limited use in hospital but it was never used recreationally. This is equivalent to a video on making tylenol. Could you try to abuse tylenol recreationally? Sure. Would it be a good time? No. Would any sane person try? No.
We hibernating through winter with this one, boys!
Yeah good luck with that.
You are actually my favourite chemistry youtuber Apoptosis, you always cover reactions that I am interested in.
Thank you so much! I'm very glad to hear it. Feel free to shoot me an email if there's anything specific you'd like me to try
He is the GOAT 🐐
@@twirlyturd4364 :) I wish I was better at taking compliments lol. So happy you guys like my videos!
@@integral_chemistry pls adrenochrome synthesis lol
I was hoping you would do a giveaway at the end of the video
Lmfao
*In the Diagram you show Br. Where is that coming from????*