Oncogenetics - Mechanism of Cancer (tumor suppressor genes and oncogenes)

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  • Опубликовано: 8 май 2024
  • Where do I get my information from: armandoh.org/resource
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Комментарии • 504

  • @MukeshMorwall
    @MukeshMorwall 3 года назад +74

    The Schools and Universities Need teachers like you .

    • @Chkoutmyvideos
      @Chkoutmyvideos 3 дня назад

      ruclips.net/video/5jGFVhpB030/видео.htmlsi=HpiqdN3JEJsBNXWI

  • @alsubaiea9869
    @alsubaiea9869 5 лет назад +307

    WOW! Incredible how you are able to make this complicated topic so much easier. Thanks a lot, you are a HERO

    • @angelmihaylov3681
      @angelmihaylov3681 3 года назад +11

      The student books use unnecessary complicated terminology.

    • @asherfrancisco7417
      @asherfrancisco7417 2 года назад

      I dont mean to be so off topic but does any of you know a trick to log back into an Instagram account?
      I somehow lost the account password. I would love any help you can offer me!

    • @zakkymiftahurrahman1665
      @zakkymiftahurrahman1665 2 года назад

      @@asherfrancisco7417 begone, BOT

    • @JonThm
      @JonThm 2 года назад

      All cancers were cured 2002
      I suggested this from my PH D work at Sheffield University 2001, that higher power ultrasound might be a novel cancer treatment. The next year the Moffitt cancer centre published 100 patient double blind trial, into High Intensity UltraSound curing all cancers and viruses.
      All foreign cell types in the human body, must have and overinflated cell nature to get cell replication in a single cell fashion. We have known since the 1950s that ultrasound scans of cancers cause the emission of X rays! We are doing biological molecular nuclear fusion.
      1 H₂O+P+HIUS→He+O+E²+X-ray

    • @JonThm
      @JonThm Год назад

      Monkeypox isn't dangerous
      cancerdone.blogspot.com/2022/05/monkeypox-isnt-dangerous.html
      Like all viruses including even AIDs and all cancers, it is cleared by ½ minute of High Intensity UltraSound to each side the chest. Cancer is cleared by 1 minute of HIUS to where it hurts.
      This causes the inflated cell structure of the foreign cell type, to boil and rupture. As he experiences biological molecular nuclear fusion. Inducing local immune system to secrete and action the active human antibody to clear the foreign cell type totally from the body.
      1 H₂O+P+HIUS→He+O+E²

  • @virnan
    @virnan 4 года назад +36

    Armando, you are gifted in many areas but one of them is your ability in simplifying complex subjects.

  • @bellal4776
    @bellal4776 3 года назад +3

    Got my cell pathology exam tomorrow and this video is brilliant, just what I needed. Thank you so much for your help!

  • @mariaorsic9763
    @mariaorsic9763 Год назад +4

    Astoundingly concise! More learning in 15 minutes than endless hours with textbook. I will purchase or donate!!!

  • @asifsiddique4783
    @asifsiddique4783 3 года назад +2

    I pray and hope your lectures help a lot more other dummies like me. Appreciate it, man! Amazing lecture.

  • @charleexiong1601
    @charleexiong1601 4 года назад +69

    It makes me so happy when I want to understand something, so I look to youtube for an explanation and Armando has covered it. He is always my first choice. Such clarity he presents to the minds of his audience

    • @Chkoutmyvideos
      @Chkoutmyvideos 3 дня назад

      ruclips.net/video/5jGFVhpB030/видео.htmlsi=HpiqdN3JEJsBNXWI

  • @ranushavelavan7598
    @ranushavelavan7598 4 года назад +3

    Amazing and thorough explanation with descriptive visuals to help us grasp this somewhat challenging topic. Thank you very much Mr. Hasudungan, looking forward to more videos like in this :)

  • @Prof.pavanjadhav
    @Prof.pavanjadhav 5 лет назад +32

    Yes.. It helped as it always does. Thank you so much. Love from India 🇮🇳

  • @tonydistefano6464
    @tonydistefano6464 5 лет назад +1

    Thank you for this video. There is so much going on in every step of the cancer process. This has help me understand the complexity of tumor growth

  • @freeradicalpanda
    @freeradicalpanda 3 года назад +1

    So much clearer when presented like this. Great work! Please keep posting.

  • @maheshbabu552
    @maheshbabu552 2 года назад +1

    Every School,College, University should have a teacher like you!! Tq sir..

  • @erikaluna6414
    @erikaluna6414 3 года назад +2

    I hope you continue making these videos, they are an insane amount of help! thank you for your time and dedication :)

  • @mohammedahmedjalloh531
    @mohammedahmedjalloh531 4 года назад +4

    Before this Video ENDS with the lack of words to describe your lecture.. I just want to say "I LOVE YOU"

  • @yankee7238
    @yankee7238 5 месяцев назад

    So neat, aesthetically pleasing illustrations, clear and concise explanation. Much appreciated love

  • @justonegoodvideo
    @justonegoodvideo 3 года назад +2

    This was a really helpful foundation to understand before studying specific cancers!
    Thanks, appreciate it a lot!

  • @thehermit5886
    @thehermit5886 Год назад +1

    Your illustrations are amazing and make it so easy to understand. Thank you!

  • @joanmacharia8730
    @joanmacharia8730 3 года назад +1

    these things never made sense till you came along.. thank you

  • @paml3742
    @paml3742 4 года назад +1

    You’re genuinely the best teacher

  • @ELPaso1990TX
    @ELPaso1990TX 2 года назад +9

    Awesome explanation! I’ve not done molecular biology for 20 years and your video is so easy to understand and feels like only yesterday I was studying molecular biology. Would so love to do a masters degree or PhD in oncology but it was probably too long ago since my degree.

  • @hassansharaya
    @hassansharaya 4 года назад +2

    I loved your video, I really struggled to understand the mechanism of cancer formation. After watching this video I feel I have a strong foundation to further learn about cancers

  • @erikmuller9270
    @erikmuller9270 2 года назад +1

    Man, you're amazing! Thank you so much. I was hanging over my text book all day, trying to understand this and finally you saved me. I'd subscribe like 8 times, if I could. Wishing you all the best and stay healthy my friend.
    Greetings from Germany.

  • @itg1262
    @itg1262 3 года назад +1

    You are excellent in articulating the topic. Nicely done

  • @pastorpeterkim
    @pastorpeterkim 3 года назад +1

    best of best lectures. You have such an excellent logical smooth way of explanining a thing.

  • @mrsdiggory3211
    @mrsdiggory3211 5 лет назад +3

    Thank youuu! I have an exam soon and this really clears everything up! x

  • @angelaedhere639
    @angelaedhere639 4 года назад +1

    Thank you so much! You provided a lot of clarity on such a complicated topic.
    God bless you!

  • @lisatryemka9775
    @lisatryemka9775 3 года назад

    Thank you! Your diagrams were very creative and flowed well with the subjects discussed.

  • @we_are_made_of_love6784
    @we_are_made_of_love6784 2 года назад

    God bless the genius that was able to talk so smoothly, clearly and incredibly deep and yet specific enough to a simple and clear understanding of oncogenes. thanks!

  • @tiujasmine1601
    @tiujasmine1601 Год назад +1

    Thank you for explaining hard topics in a very simple way!

  • @nathansherman5640
    @nathansherman5640 3 года назад +1

    Thank you, this pretty much perfectly sums up the first 3 chapters of my oncology textbook. This makes much more sense in video format than text

  • @asramohammadi9339
    @asramohammadi9339 2 года назад

    How beautiful. ❤️🥺 Thank you. Such a sweet explanation with such extraordinary flowcharts

  • @nishadr.7637
    @nishadr.7637 2 года назад +1

    props to you for explaining it better than my bio teacher ever could

  • @Jindy2
    @Jindy2 4 года назад +1

    Clear, concise and easy to understand. Just great. Many thanks.

  • @dr.sammasud7401
    @dr.sammasud7401 2 года назад

    The video is very helpful, easy to understand, to the point and full of essential information. So so helpful to understand complex topic. Thanks

  • @laughhubke.9699
    @laughhubke.9699 3 года назад

    Wow! Finally i got someone who could explain the complex topic in an undestandible way,, thanks👍

  • @HauntyMonty
    @HauntyMonty 3 года назад +7

    6:15 oncogenes: ras gene , myc gene
    9:12 tumour suppressor gene: p53, brca 1/2 ,apc

  • @chelseahaas1467
    @chelseahaas1467 4 года назад +10

    This was an awesome and well explained video! Thank you for being such a great teacher on a really complex topic! I would love to have that picture to reference when studying. Are you able to post a link of the picture you drew?

  • @berfinkizi5831
    @berfinkizi5831 6 лет назад +17

    You are amazing teacher.. İ wish i was your student.

  • @shambhavitrivedi4550
    @shambhavitrivedi4550 6 лет назад +2

    Amazing as always!!😍
    Thankyou !

  • @noumidiakarabila9514
    @noumidiakarabila9514 2 года назад +1

    i became more happy😊 and interested in a subject every time i watch your videos .
    thank you so much

  • @user-mk9bv7nn5g
    @user-mk9bv7nn5g 2 месяца назад

    Brilliant explanation !! The way you broke the topic and made it interesting and easy to understand, sir hats off to you.

  • @asiyaijaz2835
    @asiyaijaz2835 5 лет назад +1

    having no words sir... outstanding❤

  • @Melzare
    @Melzare 6 лет назад +3

    Wow!! What timing. I have a test on this Thursday and was about to search for videos.

    • @WaqarAhmed-ec5xp
      @WaqarAhmed-ec5xp 6 лет назад +1

      Melzare goodluck mate

    • @soumyasumanvlogs8272
      @soumyasumanvlogs8272 6 лет назад +1

      Melzareruclips.net/video/boKtAsGbwY8/видео.html plz subscribe my channel on RUclips. For more videos

  • @thenightdances21
    @thenightdances21 2 месяца назад

    This video is VERY important for the MCAT biology & biochem section! RAS and MYC comes up frequently on the bio/biochem passages!! Thank you SO much for explaining this clearly!!

  • @futureDrNLB
    @futureDrNLB 4 года назад

    I wish I discovered when I was taking cancer biology this would have lowered my learning covering significantly. I will share your youtube with friends who are currently taking cancer biology.

  • @mahdiomidvar564
    @mahdiomidvar564 2 года назад +1

    armando i pass the exam of pathology just because of great explanations .... i really thank you from the bottom of my heart.... .

  • @gulsumbicer299
    @gulsumbicer299 2 года назад

    it is the most beneficial video ı have ever watched about this topic on youtube. Reaaly thank you for making this video.

  • @celebritytrendtv2183
    @celebritytrendtv2183 Год назад

    Everytime I watch this video, I wish I could give it another like........ So comprehensive

  • @ayaibrahim6227
    @ayaibrahim6227 2 года назад +4

    im gonna do my AS bio mcq paper in 2 weeks and im absolutely so thankful for having these videos as revision, especially in a different way of teaching than my biology teacher, god bless him. thank you so much i'll never forget this

    • @Chkoutmyvideos
      @Chkoutmyvideos 3 дня назад

      ruclips.net/video/5jGFVhpB030/видео.htmlsi=HpiqdN3JEJsBNXWI

  • @norj25
    @norj25 Год назад

    i loved how he simplifed this very complex concept is!!!

  • @eloramichelle7948
    @eloramichelle7948 7 месяцев назад

    Man I’ve been in patho physiology lost and you my friend just explained oncogenes like a pro

  • @nonamefound9296
    @nonamefound9296 2 года назад +1

    You just saved my life, thank you sooo much!

  • @devavarrshinie16
    @devavarrshinie16 7 месяцев назад

    my lecture taught me for 2 hours and you taught me just in 11 mins and i understood everything.Thank you🙏

  • @svan1778
    @svan1778 27 дней назад

    This is great! Currently watching this at 4:30 am before my 9:00 am bio exam!

  • @jovana7366
    @jovana7366 4 года назад +1

    Good job! Very precisely described and easy to follow.

  • @NhanLe-jt6gh
    @NhanLe-jt6gh Месяц назад

    You're so great !! I've struggled this topics for so long and can't get it

  • @sharonsia1064
    @sharonsia1064 2 года назад

    so much clearer and marked in mind with your flow diagrams. TQ !!!

  • @nabilamutiarani6048
    @nabilamutiarani6048 2 года назад

    thank you so much please keep making another video like this, you really help me

  • @chandrakiransahu6600
    @chandrakiransahu6600 9 месяцев назад

    Omg I was so tensed that how I would even understand this earlier but now you've simply made it so crystal clear

  • @inesochmann3263
    @inesochmann3263 2 года назад

    Thank you so much for your fantastic work! now I finally understand the connections between p53 and p21 👍

  • @paulschult7161
    @paulschult7161 3 года назад

    This is perfect, thank you so much. Your explanation rlly helped me a lot for my exam 💯🙌🏼🙌🏼🙌🏼

  • @sultanmahmood9634
    @sultanmahmood9634 Год назад

    thanks a lot, direct, precise & very easy way to demonstrate

  • @a1icecold
    @a1icecold 5 лет назад +79

    One thing missing from this video is the one hit two-hit mechanism of oncogenes and ts genes. We have two copies of all genes, for cancer/neoplasia to occur through oncogenes only one of two gene copies need activating mutations whereas both copies of the tumor suppressor gene to inactivate/mutate before neoplasia can occur.

    • @edthoreum7625
      @edthoreum7625 5 лет назад

      ALSO,,, how can the transcription factor m-myc which plays aN important role
      in iPSC also become an oncogene? (5:20)

    • @debabratalaik9296
      @debabratalaik9296 4 года назад

      @@DNielsen113 elaborate plz

    • @arsalanarif4287
      @arsalanarif4287 3 года назад +2

      Debabrata Laik he is right because tumor suppressor gene if one become mutant so second gene from maternal or paternal works and that is able for control cell cycle so both genes of tumor suppressor should become mutant for a cell to become neoplastic

    • @natashasalmelin720
      @natashasalmelin720 3 года назад +8

      @@edthoreum7625 This is one year late, but I'll still answer. Myc is a proto-oncogene, meaning that a normal Myc will not cause cancer. Only when Myc is mutated so it is abnormally overexpressed will it be an onogene and cause cancer. A normal Myc, like in the iPS cells are important for the reasons mentioned in the video (growt & survival). In fact Myc is very important during development and cannot be knocked down or removed, because of its regulatory mechanisms of growth and survival. We wouldn't have genes that causes cancer, if it wouldn't be necessary. Hope this helps and here is a link of videos that go into more detail about cancer evolution etc: ruclips.net/video/sa5X97OQLHs/видео.html

    • @user-kp5yi7hb4z
      @user-kp5yi7hb4z 2 года назад +1

      Where are you from bro?

  • @drvinukrishnan3169
    @drvinukrishnan3169 3 года назад

    awesome....
    excellent presentation with superb drawings making a complicated subject into extra fluid style...
    great sir

  • @lillaermy7987
    @lillaermy7987 6 лет назад +1

    OMG ! Love it ! You are such an angel !!!

  • @LovetheLoveliness
    @LovetheLoveliness 5 лет назад +3

    very helpful and neatly organized! love your videos :)

  • @selsabilblh3609
    @selsabilblh3609 3 года назад

    You are a legend...THANK YOU it helped me a lot ! Respect from Algeria

  • @hariharababu3929
    @hariharababu3929 4 года назад +2

    Thank you so much for your wonderful presentation and lecture.. it really makes me to understand what it is and how it is??

  • @monaoconnell5650
    @monaoconnell5650 2 года назад

    Outstanding! Hope you com back!

  • @khadigamohamed117
    @khadigamohamed117 2 года назад

    Amazing way in teaching. Thank you for such excellent lesson.

  • @amandajones6160
    @amandajones6160 Год назад

    I would love to have your drawing from the end of the video. This has helped me so much!

  • @kitterzy
    @kitterzy 6 лет назад +5

    So much easier to understand!

  • @mohammedkaleemkhan9585
    @mohammedkaleemkhan9585 3 года назад

    Fabulous explanation Dr

  • @entisaralhaddar4005
    @entisaralhaddar4005 3 года назад

    Thank you so much! You make the complicated look so simple

  • @ramachandraiahgosu758
    @ramachandraiahgosu758 Год назад

    Thank you. Very educative and simplified to understand the complex subject

  • @iman_ktb
    @iman_ktb 2 года назад

    Thank you so much.. i didn't have much time to read pdfs..so this was really helpful

  • @caragillotti7791
    @caragillotti7791 6 лет назад

    Fantastic as always. Thank you!

  • @drwasim516
    @drwasim516 Год назад

    Super explanation dear professor

  • @theincrediblemd9761
    @theincrediblemd9761 Год назад

    Absolutely AMAZING !!! 👏 I wanted him to go on and on about BRCA 1, BRCA 2, APC

  • @amaymay2158
    @amaymay2158 Год назад

    Thank you so much for this video! My final exam is tomorrow and this helped me alot! ❤

  • @peaceyya2181
    @peaceyya2181 2 месяца назад

    thank you for imparting this knowledge ❤️❤️I now understand the molecular basis of cancer

  • @amancharan8184
    @amancharan8184 2 года назад

    This video wad so helpful for me. Thank you soo much your video have cleared all the doubts about Oncogenetics.

  • @olayinkaidowu9492
    @olayinkaidowu9492 4 года назад +1

    New subscriber here I am studying for genetics, this was so helpful.

  • @safilotra
    @safilotra 5 лет назад +2

    I loved this, thank you so much!

  • @biologyexpert586
    @biologyexpert586 3 года назад +1

    Teaching method is really very good

  • @hayleybrooks04
    @hayleybrooks04 Месяц назад

    Thank you so much. I wish you taught our class.

  • @udayvaniya4220
    @udayvaniya4220 4 года назад +1

    Thank you for this video,, you are doing great job, Keep it up!!

  • @janelpoisson7549
    @janelpoisson7549 3 года назад

    Just the most helpful video ever. Thank you so much!!

  • @jhpa0308
    @jhpa0308 4 года назад

    Incredible, Fantastic, Amazing. Thank you so much.

  • @eriquelukong2149
    @eriquelukong2149 3 года назад

    Gem caliber delivery. Well done. Thank you very much

  • @sunil7549
    @sunil7549 3 месяца назад +1

    Ohhh my god!!!!!
    Sir , you're damn good , day after tomorrow is note submission of cancer biology and if the notes are not submitted on time my teacher will not allow me to attend the class and somehow you've saved me from that, by clearing the concepts through linking various things , thank you once again sir !!!
    From India 🇮🇳🇮🇳🇮🇳

  • @anapaulaalcantara
    @anapaulaalcantara 4 года назад +1

    You are amazing teacher.. Thank you! You save me!

  • @helyrbhatiya
    @helyrbhatiya 5 лет назад

    More than perfect it was sir !

  • @lrs1675
    @lrs1675 5 лет назад

    thank you so much for explaining this. You're the best!

  • @dongleylovebasketball8732
    @dongleylovebasketball8732 3 года назад

    I think your are best you tube Lecturer

  • @martinlettrich631
    @martinlettrich631 4 года назад

    Very helpful video, you make everything seem so easy :-) Thank you very much! Love from Slovakia

  • @justsareb
    @justsareb 5 лет назад

    very very helpul , whole heartedly wish you success mr.armando

  • @saipien2868
    @saipien2868 3 года назад

    This video was very helpful. Thanks so much.

  • @faruqueazamwalid219
    @faruqueazamwalid219 4 года назад +1

    Thanks a lot...very informative in the understanding of cellular mechanism of cancer

  • @bts_rollercosterlifepurplearmy

    Your presentation is awesome 👍👍👍