Oncogenetics - Mechanism of Cancer (tumor suppressor genes and oncogenes)

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  • Опубликовано: 14 дек 2024

Комментарии • 544

  • @armandohasudungan
    @armandohasudungan  21 день назад

    🎥 DON'T JUST WATCH, LEARN ACTIVELY! TRY THE QUIZ! 🤓
    youmakr.ai/test-playground/questionnaire/673d3be7859b9c170836ec9c

  • @MukeshMorwall
    @MukeshMorwall 3 года назад +121

    The Schools and Universities Need teachers like you .

    • @Chkoutmyvideos
      @Chkoutmyvideos 7 месяцев назад

      ruclips.net/video/5jGFVhpB030/видео.htmlsi=HpiqdN3JEJsBNXWI

  • @Abdbd_1
    @Abdbd_1 5 лет назад +337

    WOW! Incredible how you are able to make this complicated topic so much easier. Thanks a lot, you are a HERO

    • @angelmihaylov3681
      @angelmihaylov3681 4 года назад +11

      The student books use unnecessary complicated terminology.

    • @asherfrancisco7417
      @asherfrancisco7417 3 года назад

      I dont mean to be so off topic but does any of you know a trick to log back into an Instagram account?
      I somehow lost the account password. I would love any help you can offer me!

    • @zakkymiftahurrahman1665
      @zakkymiftahurrahman1665 3 года назад

      @@asherfrancisco7417 begone, BOT

    • @Chkoutmyvideos
      @Chkoutmyvideos 7 месяцев назад

      ruclips.net/video/5jGFVhpB030/видео.htmlsi=HpiqdN3JEJsBNXWI

  • @virnan
    @virnan 4 года назад +47

    Armando, you are gifted in many areas but one of them is your ability in simplifying complex subjects.

  • @charleexiong1601
    @charleexiong1601 5 лет назад +77

    It makes me so happy when I want to understand something, so I look to youtube for an explanation and Armando has covered it. He is always my first choice. Such clarity he presents to the minds of his audience

    • @Chkoutmyvideos
      @Chkoutmyvideos 7 месяцев назад

      ruclips.net/video/5jGFVhpB030/видео.htmlsi=HpiqdN3JEJsBNXWI

  • @HauntyMonty
    @HauntyMonty 4 года назад +11

    6:15 oncogenes: ras gene , myc gene
    9:12 tumour suppressor gene: p53, brca 1/2 ,apc

  • @lakshmib738
    @lakshmib738 Месяц назад +1

    I want you to know that you are realllyyy amazing and no matter how old you get; kids, people of all generation who are in need of knowledge will always find you and appreciate your art of teaching .....I love your work

  • @brandongwinn5313
    @brandongwinn5313 6 дней назад +1

    Possibly the best video for my cell bio class I've ever seen!!

  • @yangsarangbi
    @yangsarangbi 2 месяца назад +1

    Idk how my professors felt it was okay to just read off the textbook and not explain such a vital topic. Thx man, you’re a savior

  • @Prof.pavanjadhav
    @Prof.pavanjadhav 5 лет назад +33

    Yes.. It helped as it always does. Thank you so much. Love from India 🇮🇳

  • @a1icecold
    @a1icecold 6 лет назад +80

    One thing missing from this video is the one hit two-hit mechanism of oncogenes and ts genes. We have two copies of all genes, for cancer/neoplasia to occur through oncogenes only one of two gene copies need activating mutations whereas both copies of the tumor suppressor gene to inactivate/mutate before neoplasia can occur.

    • @edthoreum7625
      @edthoreum7625 5 лет назад

      ALSO,,, how can the transcription factor m-myc which plays aN important role
      in iPSC also become an oncogene? (5:20)

    • @debabratalaik9296
      @debabratalaik9296 5 лет назад

      @@DNielsen113 elaborate plz

    • @arsalanarif4287
      @arsalanarif4287 4 года назад +2

      Debabrata Laik he is right because tumor suppressor gene if one become mutant so second gene from maternal or paternal works and that is able for control cell cycle so both genes of tumor suppressor should become mutant for a cell to become neoplastic

    • @natashasalmelin720
      @natashasalmelin720 3 года назад +8

      @@edthoreum7625 This is one year late, but I'll still answer. Myc is a proto-oncogene, meaning that a normal Myc will not cause cancer. Only when Myc is mutated so it is abnormally overexpressed will it be an onogene and cause cancer. A normal Myc, like in the iPS cells are important for the reasons mentioned in the video (growt & survival). In fact Myc is very important during development and cannot be knocked down or removed, because of its regulatory mechanisms of growth and survival. We wouldn't have genes that causes cancer, if it wouldn't be necessary. Hope this helps and here is a link of videos that go into more detail about cancer evolution etc: ruclips.net/video/sa5X97OQLHs/видео.html

    • @أحمدمنصور-س2ز
      @أحمدمنصور-س2ز 3 года назад +1

      Where are you from bro?

  • @mohammedahmedjalloh531
    @mohammedahmedjalloh531 4 года назад +5

    Before this Video ENDS with the lack of words to describe your lecture.. I just want to say "I LOVE YOU"

  • @ayaibrahim6227
    @ayaibrahim6227 2 года назад +4

    im gonna do my AS bio mcq paper in 2 weeks and im absolutely so thankful for having these videos as revision, especially in a different way of teaching than my biology teacher, god bless him. thank you so much i'll never forget this

    • @Chkoutmyvideos
      @Chkoutmyvideos 7 месяцев назад

      ruclips.net/video/5jGFVhpB030/видео.htmlsi=HpiqdN3JEJsBNXWI

  • @maheshbabu552
    @maheshbabu552 3 года назад +1

    Every School,College, University should have a teacher like you!! Tq sir..

  • @sunil7549
    @sunil7549 10 месяцев назад +1

    Ohhh my god!!!!!
    Sir , you're damn good , day after tomorrow is note submission of cancer biology and if the notes are not submitted on time my teacher will not allow me to attend the class and somehow you've saved me from that, by clearing the concepts through linking various things , thank you once again sir !!!
    From India 🇮🇳🇮🇳🇮🇳

  • @bellal4776
    @bellal4776 3 года назад +4

    Got my cell pathology exam tomorrow and this video is brilliant, just what I needed. Thank you so much for your help!

  • @minmyatzaw621
    @minmyatzaw621 2 месяца назад +1

    Who can be a better teacher than you!

  • @mahdiomidvar564
    @mahdiomidvar564 3 года назад +1

    armando i pass the exam of pathology just because of great explanations .... i really thank you from the bottom of my heart.... .

  • @mariaorsic9763
    @mariaorsic9763 2 года назад +5

    Astoundingly concise! More learning in 15 minutes than endless hours with textbook. I will purchase or donate!!!

  • @ELPaso1990TX
    @ELPaso1990TX 2 года назад +10

    Awesome explanation! I’ve not done molecular biology for 20 years and your video is so easy to understand and feels like only yesterday I was studying molecular biology. Would so love to do a masters degree or PhD in oncology but it was probably too long ago since my degree.

  • @noumidiakarabila9514
    @noumidiakarabila9514 3 года назад +1

    i became more happy😊 and interested in a subject every time i watch your videos .
    thank you so much

  • @asifsiddique4783
    @asifsiddique4783 3 года назад +2

    I pray and hope your lectures help a lot more other dummies like me. Appreciate it, man! Amazing lecture.

  • @drwasim516
    @drwasim516 2 года назад

    Super explanation dear professor

  • @we_are_made_of_love6784
    @we_are_made_of_love6784 2 года назад

    God bless the genius that was able to talk so smoothly, clearly and incredibly deep and yet specific enough to a simple and clear understanding of oncogenes. thanks!

  • @devavarrshinie16
    @devavarrshinie16 Год назад

    my lecture taught me for 2 hours and you taught me just in 11 mins and i understood everything.Thank you🙏

  • @xgeneproteinx2889
    @xgeneproteinx2889 2 года назад +4

    Splendid. Combination of art and biology. Very informative.

    • @loveworld8423
      @loveworld8423 2 года назад

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    • @loveworld8423
      @loveworld8423 2 года назад

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  • @pastorpeterkim
    @pastorpeterkim 4 года назад +1

    best of best lectures. You have such an excellent logical smooth way of explanining a thing.

  • @nonamefound9296
    @nonamefound9296 2 года назад +1

    You just saved my life, thank you sooo much!

  • @svan1778
    @svan1778 8 месяцев назад

    This is great! Currently watching this at 4:30 am before my 9:00 am bio exam!

  • @yankee7238
    @yankee7238 Год назад

    So neat, aesthetically pleasing illustrations, clear and concise explanation. Much appreciated love

  • @thehermit5886
    @thehermit5886 2 года назад +1

    Your illustrations are amazing and make it so easy to understand. Thank you!

  • @thenightdances21
    @thenightdances21 9 месяцев назад

    This video is VERY important for the MCAT biology & biochem section! RAS and MYC comes up frequently on the bio/biochem passages!! Thank you SO much for explaining this clearly!!

  • @freeradicalpanda
    @freeradicalpanda 4 года назад +1

    So much clearer when presented like this. Great work! Please keep posting.

  • @eloramichelle7948
    @eloramichelle7948 Год назад

    Man I’ve been in patho physiology lost and you my friend just explained oncogenes like a pro

  • @paml3742
    @paml3742 4 года назад +1

    You’re genuinely the best teacher

  • @hassansharaya
    @hassansharaya 4 года назад +2

    I loved your video, I really struggled to understand the mechanism of cancer formation. After watching this video I feel I have a strong foundation to further learn about cancers

  • @joanmacharia8730
    @joanmacharia8730 4 года назад +1

    these things never made sense till you came along.. thank you

  • @itg1262
    @itg1262 3 года назад +1

    You are excellent in articulating the topic. Nicely done

  • @nishadr.7637
    @nishadr.7637 3 года назад +1

    props to you for explaining it better than my bio teacher ever could

  • @k__dija976
    @k__dija976 2 месяца назад +1

    Are you fr!❤️❤️❤️🫠🤌🏻 I can’t believe that I learn this difficult topic within 11 minutes. 😮 thankyou 🎀

  • @mahnoorjalees5386
    @mahnoorjalees5386 9 месяцев назад +1

    Super lecture.👌

  • @assiatikkent2847
    @assiatikkent2847 3 года назад +1

    I love you
    You clarified everything and I hope this will help me have this grade
    god bless you

  • @user-lr1if9dm7b
    @user-lr1if9dm7b 5 месяцев назад

    This is fantastic. I’m studying for my OCN certification and having visual imagery really helps. Subscribed!!!

  • @celebritytrendtv2183
    @celebritytrendtv2183 2 года назад

    Everytime I watch this video, I wish I could give it another like........ So comprehensive

  • @ck_xpp
    @ck_xpp Год назад

    Omg I was so tensed that how I would even understand this earlier but now you've simply made it so crystal clear

  • @ritapaulchoudhury623
    @ritapaulchoudhury623 6 месяцев назад

    I am searching such a vdo for a long time to better clearification and now i get this !😍
    The way u r explaining in a well manner ..step by step ...😍
    Appreciating !👏
    Thank you sir ,thank you ♥️

  • @berfinkizi5831
    @berfinkizi5831 6 лет назад +17

    You are amazing teacher.. İ wish i was your student.

  • @nathansherman5640
    @nathansherman5640 3 года назад +1

    Thank you, this pretty much perfectly sums up the first 3 chapters of my oncology textbook. This makes much more sense in video format than text

  • @ranushavelavan7598
    @ranushavelavan7598 4 года назад +4

    Amazing and thorough explanation with descriptive visuals to help us grasp this somewhat challenging topic. Thank you very much Mr. Hasudungan, looking forward to more videos like in this :)

  • @mariasapientiaeameke3201
    @mariasapientiaeameke3201 2 месяца назад

    thank you immensely for this video. it is like levelling a mountain and making it not only climbable but cultivable! May God richly bless you!!!

  • @justonegoodvideo
    @justonegoodvideo 3 года назад +2

    This was a really helpful foundation to understand before studying specific cancers!
    Thanks, appreciate it a lot!

  • @erikaluna6414
    @erikaluna6414 3 года назад +2

    I hope you continue making these videos, they are an insane amount of help! thank you for your time and dedication :)

  • @sibghaabbas146
    @sibghaabbas146 3 года назад +2

    This was so brief video covering all the points..I pray to ALLAH to Give you reward and BLESS You With Guidance to straight Path

  • @juliansantos3342
    @juliansantos3342 2 месяца назад

    Amazing presentation, the best presentation on this subject in all youtube

  • @StutiDash-k5e
    @StutiDash-k5e 9 месяцев назад

    Brilliant explanation !! The way you broke the topic and made it interesting and easy to understand, sir hats off to you.

  • @Melzare
    @Melzare 6 лет назад +3

    Wow!! What timing. I have a test on this Thursday and was about to search for videos.

    • @WaqarAhmed-ec5xp
      @WaqarAhmed-ec5xp 6 лет назад +1

      Melzare goodluck mate

    • @soumyasumanvlogs8272
      @soumyasumanvlogs8272 6 лет назад +1

      Melzareruclips.net/video/boKtAsGbwY8/видео.html plz subscribe my channel on RUclips. For more videos

  • @ahgase_got7665
    @ahgase_got7665 2 года назад

    Thank you so much .God bless you

  • @tiujasmine1601
    @tiujasmine1601 2 года назад +1

    Thank you for explaining hard topics in a very simple way!

  • @theincrediblemd9761
    @theincrediblemd9761 2 года назад

    Absolutely AMAZING !!! 👏 I wanted him to go on and on about BRCA 1, BRCA 2, APC

  • @dongleylovebasketball8732
    @dongleylovebasketball8732 3 года назад

    I think your are best you tube Lecturer

  • @dr.sammasud7401
    @dr.sammasud7401 3 года назад

    The video is very helpful, easy to understand, to the point and full of essential information. So so helpful to understand complex topic. Thanks

  • @futureDrNLB
    @futureDrNLB 4 года назад

    I wish I discovered when I was taking cancer biology this would have lowered my learning covering significantly. I will share your youtube with friends who are currently taking cancer biology.

  • @amaymay2158
    @amaymay2158 Год назад

    Thank you so much for this video! My final exam is tomorrow and this helped me alot! ❤

  • @lisatryemka9775
    @lisatryemka9775 4 года назад

    Thank you! Your diagrams were very creative and flowed well with the subjects discussed.

  • @laughhubke.9699
    @laughhubke.9699 3 года назад

    Wow! Finally i got someone who could explain the complex topic in an undestandible way,, thanks👍

  • @erikmuller9270
    @erikmuller9270 3 года назад +1

    Man, you're amazing! Thank you so much. I was hanging over my text book all day, trying to understand this and finally you saved me. I'd subscribe like 8 times, if I could. Wishing you all the best and stay healthy my friend.
    Greetings from Germany.

  • @hariharababu3929
    @hariharababu3929 5 лет назад +2

    Thank you so much for your wonderful presentation and lecture.. it really makes me to understand what it is and how it is??

  • @asramohammadi9339
    @asramohammadi9339 3 года назад

    How beautiful. ❤️🥺 Thank you. Such a sweet explanation with such extraordinary flowcharts

  • @mohanapriya6249
    @mohanapriya6249 2 года назад +1

    Well understand sir. Thank you 🙏.
    Can you please explain particularly about colorectal cancer? Please

  • @jovana7366
    @jovana7366 4 года назад +1

    Good job! Very precisely described and easy to follow.

  • @LovetheLoveliness
    @LovetheLoveliness 6 лет назад +5

    very helpful and neatly organized! love your videos :)

  • @Amai002
    @Amai002 7 месяцев назад

    After 1942, Warburg showed that cancer cells metabolize glucose in a different way than normal cells, this is because tumor cells have a different mitochondrial bioenergetic function, since metabolism is directed to glycolysis, glucose uptake and lactate production, even in the presence of oxygen, making glucose uptake and glycolysis potentially faster in solid tumors than in non-cancerous tissues, this allows to explain the exceptional metabolism of this type of cells.

  • @angelaedhere639
    @angelaedhere639 4 года назад +1

    Thank you so much! You provided a lot of clarity on such a complicated topic.
    God bless you!

  • @03adityadhonkariya80
    @03adityadhonkariya80 3 года назад

    This video is enough for understanding the knowledge of Concept of cancer... 😃

  • @UmmerFaseel
    @UmmerFaseel 6 месяцев назад

    Excellent explanation to brush up genetics quickly for both undergraduate and postgraduate students as well as science enthusiasts 👍👍 brilliant work ✅✅😊

  • @samuelchinda-sb9zw
    @samuelchinda-sb9zw 6 месяцев назад

    Thank you immensely for this video.... All the scales have been unraveled 🎉❤❤

  • @sharonsia1064
    @sharonsia1064 2 года назад

    so much clearer and marked in mind with your flow diagrams. TQ !!!

  • @gulsumbicer299
    @gulsumbicer299 3 года назад

    it is the most beneficial video ı have ever watched about this topic on youtube. Reaaly thank you for making this video.

  • @biologyexpert586
    @biologyexpert586 4 года назад +1

    Teaching method is really very good

  • @amandajones6160
    @amandajones6160 Год назад

    I would love to have your drawing from the end of the video. This has helped me so much!

  • @chelseahaas1467
    @chelseahaas1467 4 года назад +10

    This was an awesome and well explained video! Thank you for being such a great teacher on a really complex topic! I would love to have that picture to reference when studying. Are you able to post a link of the picture you drew?

  • @priyankanandi1173
    @priyankanandi1173 2 месяца назад +1

    Ur genius 🧿🥂

  • @peaceyya2181
    @peaceyya2181 9 месяцев назад

    thank you for imparting this knowledge ❤️❤️I now understand the molecular basis of cancer

  • @norj25
    @norj25 Год назад

    i loved how he simplifed this very complex concept is!!!

  • @Jindy2
    @Jindy2 5 лет назад +1

    Clear, concise and easy to understand. Just great. Many thanks.

  • @monaoconnell5650
    @monaoconnell5650 3 года назад

    Outstanding! Hope you com back!

  • @hollymin747
    @hollymin747 Месяц назад

    Wow, this was the best explanation ever

  • @selsabilblh3609
    @selsabilblh3609 4 года назад

    You are a legend...THANK YOU it helped me a lot ! Respect from Algeria

  • @NhanLe-jt6gh
    @NhanLe-jt6gh 9 месяцев назад

    You're so great !! I've struggled this topics for so long and can't get it

  • @hanifdhuru5098
    @hanifdhuru5098 Год назад

    Hey Mr Armando, I really appreciate your work and I am looking forward for your lecture on breast cancer

  • @ramachandraiahgosu758
    @ramachandraiahgosu758 2 года назад

    Thank you. Very educative and simplified to understand the complex subject

  • @matheuschillemi4374
    @matheuschillemi4374 Месяц назад

    The best by far!

  • @MillieMillie33
    @MillieMillie33 3 года назад +1

    Amazing video, very well explained. Thank you.

  • @mrsdiggory3211
    @mrsdiggory3211 5 лет назад +4

    Thank youuu! I have an exam soon and this really clears everything up! x

  • @drvinukrishnan3169
    @drvinukrishnan3169 4 года назад

    awesome....
    excellent presentation with superb drawings making a complicated subject into extra fluid style...
    great sir

  • @sultanmahmood9634
    @sultanmahmood9634 2 года назад

    thanks a lot, direct, precise & very easy way to demonstrate

  • @tonydistefano6464
    @tonydistefano6464 5 лет назад +1

    Thank you for this video. There is so much going on in every step of the cancer process. This has help me understand the complexity of tumor growth

  • @bts_rollercosterlifepurplearmy

    Your presentation is awesome 👍👍👍

  • @hurmatarif8342
    @hurmatarif8342 3 месяца назад

    Thank you so much ❤please makes videos on molecular biology

  • @eriquelukong2149
    @eriquelukong2149 4 года назад

    Gem caliber delivery. Well done. Thank you very much