How to choose the right dose of Accutane (isotretinoin) | Dermatologist and acne expert explains

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  • Опубликовано: 10 окт 2024
  • I'm John Barbieri, MD, a board-certified dermatologist and acne expert at the Brigham and Women’s Hospital and Harvard Medical School. In this video we will discuss how to choose the best dose of isotretinoin and for how many months to treat. By thoughtfully individualizing dosing regimens, we can improve long-term clearance outcomes and minimize side effects.
    #isotretinoin #accutane #acne #dose #dosing #dermatologist #expert
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    References:
    Trial of different dosing regimens: pubmed.ncbi.nl...
    Long-term clearance data: pubmed.ncbi.nl...
    Disclaimer: This RUclips Channel does not provide any diagnosis, treatment or medical advice and does not replace a visit to your doctor. The statements are not intended to treat, diagnose, cure or prevent disease. See your doctor for medical advice and treatment. My statements on this channel are for informational purposes only.

Комментарии • 23

  • @CL-un1kc
    @CL-un1kc 3 месяца назад +1

    I was just looking for a Video about this topic! Thank you for educating is! 🎉

  • @maeveryan7680
    @maeveryan7680 3 месяца назад +1

    Very enlightening. Thank you!

  • @wreckedbmwguy9925
    @wreckedbmwguy9925 2 месяца назад +1

    Very helpful! Thank you.

  • @jessicaorourke9174
    @jessicaorourke9174 5 дней назад +1

    Thank you so much for all of this info!!! I'm just starting and curious if I take my pill in the morning with 2-4T Olive Oil, is that sufficient for absorbtion or do you need solid food with it as well?

    • @DrJohnBarbieri
      @DrJohnBarbieri  5 дней назад

      I can't speak to your specific situation, and no one has specifically looked at olive oil, but 2-4T of olive oil is about 25-50g of fat, which one would expect is likely sufficient.

    • @jessicaorourke9174
      @jessicaorourke9174 4 дня назад

      ​@@DrJohnBarbieri Thank you so much for the response!

  • @Macorelppa
    @Macorelppa 3 месяца назад +3

    Load up on 40mg/kg per day for 6 months and say 👋 to acne for good!

  • @anthonycareccia3488
    @anthonycareccia3488 2 месяца назад +1

    What are your thoughts on different brand. I’m on 64 mg of Absorica LD with no progress

    • @DrJohnBarbieri
      @DrJohnBarbieri  2 месяца назад

      I don't think the brand matters that much. For some who have trouble with absorption, using a Lidose isotretinoin (Absorica) or micronized isotretinoin (Absorica-LD) can be helpful and can make dosing more consistent. But I think most can do well with any formulation of isotretinoin (just might need a higher dose with standard isotretinoin).

    • @anthonycareccia3488
      @anthonycareccia3488 2 месяца назад

      @@DrJohnBarbieri thanks. I have like no side effects despite a little dryness, do you think I should ask to go up past 64 daily after the month ends

  • @sidv2795
    @sidv2795 8 дней назад +1

    To permanently cure acne 120mg per kg cummalative dose necessary for everyone ?

    • @DrJohnBarbieri
      @DrJohnBarbieri  8 дней назад

      No. In general, higher cumulative doses are associated with greater likelihood of long-term clearance, but some people need higher doses and some need lower doses. Achieving clear skin x2-3 months before stopping is a good predictor of long-term clearance.

    • @sidv2795
      @sidv2795 8 дней назад

      @@DrJohnBarbieri and what type of blood test is done while on Accutane i mean what elements are essential in the report

  • @annasmith8063
    @annasmith8063 Месяц назад

    hi Dr, just started very low dose accutane and was wondering, if i take it at 5:00am one day, can i take it at 6:30am the nest day or does it have to be exactly at 5:00am everyday? I appreciate all of your content!

    • @DrJohnBarbieri
      @DrJohnBarbieri  Месяц назад +1

      In general (not speaking to your specific situation), the most important thing in terms of timing of when to take isotretinoin is to make sure it is taken with a meal that has fat in it (to help with absorption; for Lidose/micronized isotretinoin this is less of an issue).

  • @tnjin5760
    @tnjin5760 20 дней назад

    It’s been 1 and half months on accutine . But i am not seeing much progress. What should i do now?( I am taking 20mg per day)

    • @DrJohnBarbieri
      @DrJohnBarbieri  19 дней назад

      I cannot comment on what is best for you (you should discuss with your doctor). In general, a treatment course of isotretinoin is at least 5-8 months.