Helpful Pneumonic on the symptoms of Parkinsons: TRAP (as in you are trapped in your own body) Tremors Rigidity Akinesia (low movement) Postural immobility
I love your videos Armando... One error I'd point out in this one is that dopamine loss does not cause tremous in PD, deranged acetylcholine circuits are responsible for this. Dopamine actually accentuates motor signalling by exciting the direct pathway (which is itself excitatory) and inhibiting the indirect pathway (which is inhibitory). Thus reduction in dopamine --> reduction in motor signalling --> bradykinaesia. Keep up the good work mate!
Armando, you have come along way with your videos. I applaud your artistic prowess and teaching skills.Your videos help me so much since I am an auditory-visual learner. Thumbs up always!!!!
This song was stuck in my head all weekend (which is a GOOD thing with a test coming up) so thank you!!! Very helpful. Please make more! :) :) - Nursing student.
Can a person with Parkinson’s have involuntary movements but no tremors? Many people who have Huntington’s can be misdiagnosed as having Parkinson’s. What is the clear difference between the two in terms of movements? Or can they be very similar? Can a person have involuntary movements and no tremors and still have Parkinson’s? Or would that indicate a possibility of Huntington’s?
for Huntington disease, some sources say a mutatian in Huntington Gene that produce huntington protein which have more glutamate compared with normal protein. However, in this video you mentioned about lacking of GABA. well to be honest I'm confused a little bit.
+mehmet aLi GABA is inhibitory and Glutamate is excitatory. So reduced GABA or increased Glutamate will give you the same effect. Both are neurotransmitters in the basal ganglia which is responsible for movements. Hope that helps. You might want to take a look at some videos on Basal ganglia direct and indirect pathways.
I love this video and the animations!! I am taking a patho class currently and often refer to other videos to further understand. I am left a little confused though because my patho professor said that there is actually an excess of dopamine levels and upon further research I have read that there are increased levels of dopamine, but in your video you said that dopamine levels remain normal?
Really amazing video, it is very very helpful for my studies. May I ask, based on the video, is dopamine continually released, and is it continually released due to us thinking of most of the time? Is that why the shakes occur (rapid intentions to move), taking into account reduction in GABA.
bro your videos are awesome but can you plz make this video once more this has low voice quality nd pictures are very small plz its a request your videos are very helpful In my med school
genius wre is the explanation about the direct nd indirect pathways involving {globus pallidus,substantia nigra,subthalamic nuclei,anterior and lateral thalamic path ways}? whatever is hapening in basal ganglia is just a game between then ...wats the point explaining the disorder without explaining the pathway??anyways...ur sketches r good ...
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Helpful Pneumonic on the symptoms of Parkinsons: TRAP (as in you are trapped in your own body)
Tremors
Rigidity
Akinesia (low movement)
Postural immobility
I love your videos Armando... One error I'd point out in this one is that dopamine loss does not cause tremous in PD, deranged acetylcholine circuits are responsible for this. Dopamine actually accentuates motor signalling by exciting the direct pathway (which is itself excitatory) and inhibiting the indirect pathway (which is inhibitory). Thus reduction in dopamine --> reduction in motor signalling --> bradykinaesia. Keep up the good work mate!
I am always happy that your channel exist!!
Armando, you have come along way with your videos. I applaud your artistic prowess and teaching skills.Your videos help me so much since I am an auditory-visual learner. Thumbs up always!!!!
This song was stuck in my head all weekend (which is a GOOD thing with a test coming up) so thank you!!! Very helpful. Please make more! :) :) - Nursing student.
Love your illustrations. Thanks for putting so much work into this for us!
extremely helpful and pretty understandable. im supposed to write a term paper on a named neurodegenerative disease so this really helped
Did you just apologise for talking quick at the end? Honey, you talked perfectly fine. XD
Great videos Armando!
Thanks mate. Awesome illustrations!!!
very good explanation on the differences.
would be good to do a video on indirect and direct pathway
THANK YOU! FOR MAKING A VIDEO THAT I CAN UNDERSTAND. AND SO CAN MY FAMILY AND FRIENDS.
the lecture is precise and very clear
Can a person with Parkinson’s have involuntary movements but no tremors?
Many people who have Huntington’s can be misdiagnosed as having Parkinson’s. What is the clear difference between the two in terms of movements? Or can they be very similar?
Can a person have involuntary movements and no tremors and still have Parkinson’s? Or would that indicate a possibility of Huntington’s?
Beautiful drawings, very helpful- great video. Thanks
Will a person suffering from Parkinson's disease have difficulty in stopping the initiated movement?
Really enjoying your videos, thanks!!
for Huntington disease, some sources say a mutatian in Huntington Gene that produce huntington protein which have more glutamate compared with normal protein. However, in this video you mentioned about lacking of GABA. well to be honest I'm confused a little bit.
+mehmet aLi
GABA is inhibitory and Glutamate is excitatory. So reduced GABA or increased Glutamate will give you the same effect. Both are neurotransmitters in the basal ganglia which is responsible for movements. Hope that helps. You might want to take a look at some videos on Basal ganglia direct and indirect pathways.
so easy to follow it really helps when the text books fail
Even the lectures fail
THIS VIDEO WAS PERFECT. AMAZING DRAWINGS, SO ACCURATE! YOU RULE MAN, KEEP IT UP AND THANK YOU VERY MUCH :)
could you update this video please
brilliant! keep up the awesome work!
Amazing and clear
Great video! Super helpful info
pretty sure its striatum not stratium
Good stuff!
great video !
I love this video and the animations!! I am taking a patho class currently and often refer to other videos to further understand. I am left a little confused though because my patho professor said that there is actually an excess of dopamine levels and upon further research I have read that there are increased levels of dopamine, but in your video you said that dopamine levels remain normal?
Very helpful 🙌🙌 thank you so much 🤲🙌🙌🏾🙏🏾
This was so helpful!! Thanks!
great for quick review thanks
Very informative!
Very helpful, thank you.
Such a helpful video
thank you Armando! that was a helpful overview!! : )
do you have a picture of this? this is amazing :)
Exam tomorrow, thank youuuuu :)
very helpful. thank you so much
cool video, but it's called STRIATUM, not STRATIUM
Really amazing video, it is very very helpful for my studies. May I ask, based on the video, is dopamine continually released, and is it continually released due to us thinking of most of the time? Is that why the shakes occur (rapid intentions to move), taking into account reduction in GABA.
Thank you very very much by the way
thanks for this!!
Awesome
i wonder how many studnets were misled by inaccurate info in these videos
bro your videos are awesome but can you plz make this video once more this has low voice quality nd pictures are very small plz its a request your videos are very helpful In my med school
Well explain
thank you, saved my ass on a physiology exam question. my notes had it backwards.
how to fotify dopermine
All thanks to dr Stanley who cured me from my Huntington’s disease I am forever grateful
thnk u...........
5:15 is the best part :D
genius wre is the explanation about the direct nd indirect pathways involving {globus pallidus,substantia nigra,subthalamic nuclei,anterior and lateral thalamic path ways}? whatever is hapening in basal ganglia is just a game between then ...wats the point explaining the disorder without explaining the pathway??anyways...ur sketches r good ...
striatum**
I have Parkinson’s in my right hand will eventually it move towards my left
U ROCK!!! :D :D :D
#drojeabacha