i promise you clearing up your acne feels so amazing and gives you the biggest confidence boost. i was struggling for years and it finally cleared up and i feel amazing. you got this
When I started using retinol I had no idea it could help with acne; I was using it to even out my skin tone. When the breakouts stopped I was pleasantly surprised and incredibly thankful.
This was a short but informative guide. I would recommend this acne guide *AcneCureOnline. Com* to my friends starting out on their journeys to clear skin, getting rid of acne. Greatly liked this and loved the understanding into how my inside troubles can affect my skin.?
This acne guide *AcneCureOnline. Com* was very informative and helpful. I often go through gentle adult acne and this guide discusses all the possible solutions for mild to severe acne whether natural procedures or otherwise. I prefer the natural way of treating them and I found out on this guide the treatments that work efficiently.
The most informative acne video I’ve ever seen and I’ve watched a LOT!! Thank you for keeping things clear and to the point. The visuals helped greatly as well. Thank you so much.
This channel is awesome! There's a reason why I included you in a Top 10 Biomed channels! Glad you uploaded again. This particular video (sadly enough) takes me back to my youth in a bumpy way...great explanation. Cheers from Belgium!
This was so informative and well presented! As someone who struggles a lot with acne I really appreciate being able to learn about it in a more scientific way. Would you ever consider making more skin care videos? For example, how retinoids work for anti-aging or maybe on different sunscreen filters and their mechanisms :)
I recommend you to watch the budget dermatologist for acne skincare i find her more informative about skincare ingredients that fights acne and improve skin
My dermatologist is incredibly reliable and a respected professional, but she just took 1 look at me and prescribed 1) Epiduo (Adapalene + Benzoyl Peroxide ) 2) Clindamycin 3) Oral Hormonal Therapy 4) Blood Tests to change Hormonal Therapy to a stronger one (the Pill) if needed WITHOUT ANY EXPLANATION, I wish she told me what these products are supposed to be doing. Thank you for your explanation, now I understand I need to be patient with redness, irritation, itching, peeling etc, as they’re a normal part of healing!! :D (I’ve only been doin this treatment for a month, but I can really see my acne calming down and reducing to small spots where it was less severe, now I just need to le patient and wait for my skin to regenerate like it’s supposed to)
I never had to deal with acne during puberty, but I’m now in my mid/late 20s and my face just doesn’t want to cooperate! Now I understand a little more about how my tretinoin and clindamycin work together to treat my acne. I just have to be patient...
ive been using both for years and to be honest it works and the zits come back again cause they gain resistance. its all in the genetics in my opinion but it definitly helped prevent worst case acne
meena mee Hi Meena, we are all different but for me my diet was the culprit. I did an elimination diet called the Whole 30 for a month then I transitioned to Paleo. Basically I cut out dairy, grains and sugar. I think dairy mostly added to my acne trouble. Acne was so frustrating for me, it got super bad after I had my first baby but thankfully the diet cleared me up after years of trying all the topical creams. I wish you so much luck on your journey.
@@MarifeBeshy having acne is not bad thing...that means your skin still produce oils...and that's not bad for aging ...try to find skincare products and food which suit your skin☺️
Wow I was just astonished to watch these exclusive informative videos, I have ever seen the best. Thank for more details of acne causing qnd treatment.
Really informative video! Thanks for putting this together. Also your information design was great 👌 I didn't know all the big words but I was able to follow enough to grasp the concept, I think the imagery helped!
There Is an Overload of Conflicting Information and Often Ineffective Advice on How To Treat Acne. While it took little less than two months for me to really see a difference, my acne, blackheads and whole lot of other skin problems I had…such as eczema… had completely cleared! It was totally amazing. Permanently Cure Your Acne Within 2 Months. Here > *AcneCureOnline. Com*
Hmm this is somewhat confusing on the retinoid section. It's mentioned and it's true that retinoids have to be converted to retinoic acid but the examples given I believe aren't part of that situation. Tretinoin is already bioactive retinoic acid. Adapalene and Tazarotene are both third generation retinoids that are already bioactive even though they're not retinoic acid, but they do bind to the same sites. I was hoping to get some information on what the key differences are in the pharmacology between tretinoin and adapalene.
Great content! Your clip art is amazingly good, fun and accurate! That is great for memorization. Are they produced by you or are they from any available source. I’d love to use them in my classes!
I am in my 40`s and just began with adult acne. It got seriously bad!! I didn`t experience acne before. After applying this acne guide *AcneCureOnline. Com* for 2 weeks, I observe obvious effects. I am trying this treatment for 2 months now and have become comfortable once again. .
PLEASE don't take accutane!!!!( I took only 20 mg but even low dose was bad) I am very grateful I became aware early of the side effects in my second round of accutane which was 1 year after the first round. In the first round I took accutane for 5 months on low dose for mild/ moderate acne. It drys your body organs and has caused me mild Fatty Liver Disease(which I caught on early), irregular periods, a fibroadenoma which I have mistaken for malignancy and caused huge pain and anxiety for months. Alternative: Get an estrogen test and your doctor will prescribe supplements to balance your hormone levels, which in turn will clear up your face even better than accutane. I WISH I had known all of this earlier😭
In the cells, retinoic acid enters the nucleus where it binds to heterodimers formed by two different classes of nuclear receptors: Retinoic acid receptors (RARs) and retinoid X receptor (RXRs).
This also happens to women that are menopausal see them goes up oestrogen is gone I ended up with folliculitis and prurigo nodularis. My doctor said this is my new reality this horrible crap leaking on my head when in fact I asked him to put me on Accutane because I had used it years before and it seems to be helping
Excuse me Sir, I want to ask for my research paper. So when we give antibiotics, what happens to the bacteria? Are they totally killed or reduced or deactivated or what? Because as I know, P. acnes are naturally exist in every human skins. Thank you
P. acnes is part of our skin's natural microbiome. Some but not all strains of the bacteria promote acne-causing inflammation. P. acnes colonizes primarily sebaceous glands and hair follicles but it may also be found in the mouth, nares, genitourinary tract, and large intestine. It is able to recolonize quickly after a round of antibiotics.
@@ibibercerita antibiotics commonly used in treatment of acne such as tetracycylines are inhibitors of growth (bacteriostatic) rather than killers of the bacteria. see my video about the pharmacology of antibiotics for more detailed explanation
adapalene and tretinoin have basically the same effect, so there's no reason to use both at the same time. And benzoyl peroxide and tretinoin are known for sensitizing the skin. So the chances of your skin get all irritated and sensitive are double.
If inhibiting 5-reductase enzyme lowers the amount of DHT produced in the body, will that increase the levels of one’s testosterone? Or simply due to the lack for of DHT being converted; does that simply mean the levels of free T are consequently high after suppression of DHT ?
I stopped using adapalene and my acne came back. What can I do now till I take my next dermatologist appointment ? Is there a way to stop them for a few days? Im not able to plan my dermat appointment because of busy schedule and cant risk having acne back coz I'll be having events next week.
I would recommend this acne guide *AcneCureOnline. Com* to anyone who is suffering from discovering the right acne remedies on their own. Our family is suffering from acne since then and I have tried different acne treatments. Luckily, with the help of this impressive guide, acne was cured and development was halted. .
Can someone please help me with this question : Is the hormonal therapy part of this video only for females? Can males use spironolactone? Please let me know thank you so much. :)
Minocycline is often prescribed for acne.Whether it's appropriate option for you, it's something that you would have to discuss with your dermatologist.
I really dont know what happen to me, I've acne since 14 yo but now suddenly it's getting worse, I even have acne in my head like in my scalp. I'm 20 yo now, and I dont know the caused of it 😭
@saurabhpanigrahi5429 hello, yes I still have acne but mostly caused by hormonal changes before my period and not as severe like those years ago. I actually not sure what made it dissapeared. Few things happen at them same time. I moved out to a different city (some people believe water and air can cause acne), I am no longer depressed, I drink some supplements, I go out more often (some people says sun is good for skin just not too much and always remember suncreen). I was actually almost free acne when I moved to different city. And then I move in with my parent again (it is so challenging to live with them) and my acne started to shows again despite still consuming the same supplements but not as worst as before (no acne on my scalp anymore). So I start using retinol, in my case it really help but make sure you use facial wash and moisturizer that already suit your skin because if not the retinol only would make the acne worst.
Mhm. So retinoids just unplug the follicle via pushing new cells from behind. Based on this I thought if you had psoriasis (which is characterized by quick maturation of keratinocytes) you would make everything worse if you used retinoids. I googled and I am wrong, actually it's even a treatment vs psoriasis. Anyone know why? Is it like a "restart" for the keratinocytes?
As far as I know the exact molecular mechanism by which retinoids are able to exert their effects on psoriasis is unknown. However, in psoriatic keratinocytes retinoids appear to produce antiproliferative effects, normalize abnormal differentiation, and decrease expression of inflammatory markers
But they also speed up skin turnover, which seems beneficial for someone dealing with this skin disorder as it would help prevent the buildup of skin layers. (?). It also normalizes things, which would also be helpful for preventing psoriasis-I would think.
This is so good and informative. Great video, clear and aesthetically pleasing lol.. I wanted to know what I was putting on my face. I’m confident benzoyl peroxide/ doxycycline combo + tarazotene the dr prescribed along with healthy lifestyle changes for hormonal regulation (and prayer lol) will cure my acne! 🙏🏾
i promise you clearing up your acne feels so amazing and gives you the biggest confidence boost. i was struggling for years and it finally cleared up and i feel amazing. you got this
What did you do?
@@therareexperiments2090 differin
@@marcusmassoud995 quick question I just started it. What products do you use with it
@@marcusmassoud995 Does it actually last?
@@alexisesparza3453 gentle products like cerave and no exfoliatns
Finally someone actually explained what is happening to my face
yea sure me to -- This article changed my life www.youngclear-skin.com/blog/how-get-rid-period-acne-overnight-and-prevent-acne-flare-ups/
Welcome to pharmacy 😂😂😂
Take a shower
Obito lmao
@@Slyracoon666 not how it works
When I started using retinol I had no idea it could help with acne; I was using it to even out my skin tone. When the breakouts stopped I was pleasantly surprised and incredibly thankful.
U used to have acne , like much or mild ??? How many days did it take ?? Can u please explain 😔
Use it at night
Excellent.This video tells me the whole story of acne very clearly.GOD bless you.
This was a short but informative guide. I would recommend this acne guide *AcneCureOnline. Com* to my friends starting out on their journeys to clear skin, getting rid of acne. Greatly liked this and loved the understanding into how my inside troubles can affect my skin.?
This acne guide *AcneCureOnline. Com* was very informative and helpful. I often go through gentle adult acne and this guide discusses all the possible solutions for mild to severe acne whether natural procedures or otherwise. I prefer the natural way of treating them and I found out on this guide the treatments that work efficiently.
The most informative acne video I’ve ever seen and I’ve watched a LOT!! Thank you for keeping things clear and to the point. The visuals helped greatly as well.
Thank you so much.
Finally a video that really explains everything that needs to be explained
This channel is awesome! There's a reason why I included you in a Top 10 Biomed channels! Glad you uploaded again. This particular video (sadly enough) takes me back to my youth in a bumpy way...great explanation. Cheers from Belgium!
This was so informative and well presented! As someone who struggles a lot with acne I really appreciate being able to learn about it in a more scientific way. Would you ever consider making more skin care videos? For example, how retinoids work for anti-aging or maybe on different sunscreen filters and their mechanisms :)
I don't think this channel was made for skin care, I think this is for medical or pharmacology students.
I recommend you to watch the budget dermatologist for acne skincare i find her more informative about skincare ingredients that fights acne and improve skin
Finally a video that actually explains the mechanism of action of retinoids. Thank you. Very well explained.
My dermatologist is incredibly reliable and a respected professional, but she just took 1 look at me and prescribed
1) Epiduo (Adapalene + Benzoyl Peroxide )
2) Clindamycin
3) Oral Hormonal Therapy
4) Blood Tests to change Hormonal Therapy to a stronger one (the Pill) if needed
WITHOUT ANY EXPLANATION, I wish she told me what these products are supposed to be doing.
Thank you for your explanation, now I understand I need to be patient with redness, irritation, itching, peeling etc, as they’re a normal part of healing!! :D
(I’ve only been doin this treatment for a month, but I can really see my acne calming down and reducing to small spots where it was less severe, now I just need to le patient and wait for my skin to regenerate like it’s supposed to)
How are you now?
Clindamycine was a topical antibiotic ? Or oral ?
@@loubnamihoubi2983 i think, its topical antibiotic
I never had to deal with acne during puberty, but I’m now in my mid/late 20s and my face just doesn’t want to cooperate! Now I understand a little more about how my tretinoin and clindamycin work together to treat my acne. I just have to be patient...
ive been using both for years and to be honest it works and the zits come back again cause they gain resistance. its all in the genetics in my opinion but it definitly helped prevent worst case acne
Liked before watching
YOU ELUCIDATE THE FACTORS VERY WELL. Excellent!!!
I had terrible acne from my teens until my 30’s. Changing my diet is the only thing that worked-I went paleo and the acne is gone!
Hi Sharon... I too have the same problem.... Can u give me few tips?
meena mee Hi Meena, we are all different but for me my diet was the culprit. I did an elimination diet called the Whole 30 for a month then I transitioned to Paleo. Basically I cut out dairy, grains and sugar. I think dairy mostly added to my acne trouble. Acne was so frustrating for me, it got super bad after I had my first baby but thankfully the diet cleared me up after years of trying all the topical creams. I wish you so much luck on your journey.
I am on my 30's still have acnes.. sad
@@MarifeBeshy having acne is not bad thing...that means your skin still produce oils...and that's not bad for aging ...try to find skincare products and food which suit your skin☺️
I appreciate your video sharing with us so much, as I’m medical student I suggest this video to my friends
Wow I was just astonished to watch these exclusive informative videos, I have ever seen the best. Thank for more details of acne causing qnd treatment.
Ngl but these retinoids can really boost your confidence.
I'm only using retinol and I can see the improvement on my face. 😍
Thank you so much. Only in 12 minutes you cover every thing
Best video till date on pharma ❤️
Amazing lecture 👌👍
Ma fav channel till now 👌❤
thank u soo much i had fun watching this ❤
Amazing animations! Really good video 👍
Thanks to speed pharmacology channel for giving us such a wonderful knowledge to us!
sir you really are making pharmacology so easy !
#PHARMAMADEEASY
Excellent. I only wish more RUclips videos were as informative and factual as this one.
well done thank you🙌🏻
Hey, VERY VERY GOOD MY MAN!
Appreciate the effort and technical explanation
Really informative video! Thanks for putting this together. Also your information design was great 👌 I didn't know all the big words but I was able to follow enough to grasp the concept, I think the imagery helped!
There Is an Overload of Conflicting Information and Often Ineffective Advice on How To Treat Acne. While it took little less than two months for me to really see a difference, my acne, blackheads and whole lot of other skin problems I had…such as eczema… had completely cleared! It was totally amazing. Permanently Cure Your Acne Within 2 Months. Here > *AcneCureOnline. Com*
That's true, this is also out of my depths of absolutr understanding. But the visuals really helped in telling what is going on.
Sir.. Please do a video on anticancer drugs..
its no a sir its a pharmacict u bullshit
I take blackseed oil, lemons, green tea, turmeric, hemp, ginger, tomatoes, flaxseeds, garlic, graviola.... Works instead of tablet
Hmm this is somewhat confusing on the retinoid section. It's mentioned and it's true that retinoids have to be converted to retinoic acid but the examples given I believe aren't part of that situation. Tretinoin is already bioactive retinoic acid. Adapalene and Tazarotene are both third generation retinoids that are already bioactive even though they're not retinoic acid, but they do bind to the same sites. I was hoping to get some information on what the key differences are in the pharmacology between tretinoin and adapalene.
Great content! Your clip art is amazingly good, fun and accurate! That is great for memorization. Are they produced by you or are they from any available source. I’d love to use them in my classes!
Thanks so much! This is a wonderful service
Sir please upload immunosuppressant and anticancer drugs
Such useful insights thanks for creating such informative video
Please do a video on anti tuberculosis,migraine and hormone related drugs
Great explanation, thank you!
Amazing animation and amazing explanation
I really enjoy your videos!!! Such an amazing job! Thank you!
Amazing video. Explained so much.
So, how do I find out the size of my sebaceous gland?
Guys like the vid so he gets the credit he deserves
Wowww very nformative... I'm overwhelmed
Wonderful explanation! Thank you! :)
Great illustration and explanations....
most informative video on acne problem..
I am in my 40`s and just began with adult acne. It got seriously bad!! I didn`t experience acne before. After applying this acne guide *AcneCureOnline. Com* for 2 weeks, I observe obvious effects. I am trying this treatment for 2 months now and have become comfortable once again. .
PLEASE don't take accutane!!!!( I took only 20 mg but even low dose was bad)
I am very grateful I became aware early of the side effects in my second round of accutane which was 1 year after the first round. In the first round I took accutane for 5 months on low dose for mild/ moderate acne. It drys your body organs and has caused me mild Fatty Liver Disease(which I caught on early), irregular periods, a fibroadenoma which I have mistaken for malignancy and caused huge pain and anxiety for months.
Alternative: Get an estrogen test and your doctor will prescribe supplements to balance your hormone levels, which in turn will clear up your face even better than accutane. I WISH I had known all of this earlier😭
hello, I got a fatty liver too because of accutane, could this be reversed in some way? im really scared 🥲
What if I’m a man 🤷🏽♂️
@@feddi7693 no prob
Can you do one on epidermal and dermal hyperpigmentation and PIE?
Thanks. How about PFB? would you consider doing a video on it?
Very nice sir, Thank you
Would you make a video on how isotretinoin is different from tretinoin?
Khalled Alves Isotretinion is taken orally and used to severe acne. Tretinoin is taken topically and use for mild to moderate acne.
we want a video on Psoriasis treatments
I’m surprised azelaic acid wasn’t mentioned as an antimicrobial... very good video tho
Amazing,.... Looking forward to anti- virals,.....
Thanks for your good explanation it's clearly now every one can understand now thanks but plz add more details
Thanks very informative video.
Please add more details if possible.
Good work ..
Thank you for the explanation
Thank you for your education.
What’s the hormonal therapy for men ?
Can you differentiate the difference between RAR and RCX receptors in skin ?
I’m amaze how dentist learn this
I'm confused! When converted into retionic acid, what does it bind to?
In the cells, retinoic acid enters the nucleus where it binds to heterodimers formed by two different classes of nuclear receptors: Retinoic acid receptors (RARs) and retinoid X receptor (RXRs).
Very interesting and well explained.
Sir can please explain about organo phosphate poisoning mechanism and oxime reuptake mechanism
Very informative
thank you sir 👍👍
This also happens to women that are menopausal see them goes up oestrogen is gone I ended up with folliculitis and prurigo nodularis. My doctor said this is my new reality this horrible crap leaking on my head when in fact I asked him to put me on Accutane because I had used it years before and it seems to be helping
Excuse me Sir, I want to ask for my research paper. So when we give antibiotics, what happens to the bacteria? Are they totally killed or reduced or deactivated or what? Because as I know, P. acnes are naturally exist in every human skins. Thank you
P. acnes is part of our skin's natural microbiome. Some but not all strains of the bacteria promote acne-causing inflammation. P. acnes colonizes primarily sebaceous glands and hair follicles but it may also be found in the mouth, nares, genitourinary tract, and large intestine. It is able to recolonize quickly after a round of antibiotics.
@@SpeedPharmacology but, it doesn't mean that the P. acnes will completely go away, right? They're become benign, aren't? Correct me if I'm wrong
@@ibibercerita antibiotics commonly used in treatment of acne such as tetracycylines are inhibitors of growth (bacteriostatic) rather than killers of the bacteria. see my video about the pharmacology of antibiotics for more detailed explanation
Excellent..
Explained in an Outstanding way..plz make the similer one for all anticancer agents..
Can u please do a video about drugs used for ADHD?
Sir can u plz make a video on anti viral and anti cancer drugs
Thank you
Why i used tretinoin for 1 week but my acne become acne scars even if i didnt touch my acne
Most awkward feeling when some people look at you and say what is this or go to doctor
They don't understand
Could I just wash my face with water?
Sure
Doesn’t work
Can you use adapalene with benzoyl peroxide and tretinoin together at night?
adapalene and tretinoin have basically the same effect, so there's no reason to use both at the same time. And benzoyl peroxide and tretinoin are known for sensitizing the skin. So the chances of your skin get all irritated and sensitive are double.
@@gabsprado121212 thank you very much! Such a help.
My dermatolagist prescribed me clindamycin +adaplene gel.
Keep going!! U r great
You're excellent
can we get Asthma & COPD meds
If inhibiting 5-reductase enzyme lowers the amount of DHT produced in the body, will that increase the levels of one’s testosterone? Or simply due to the lack for of DHT being converted; does that simply mean the levels of free T are consequently high after suppression of DHT ?
inhibition of 5-alpha reductase has been shown to cause a modest increase in testosterone production
@@SpeedPharmacology is Testosterone the cause for acne? Or DHT?
Sir May Allah bless you♥♥
All these treatments and still zero effect to my skin...
I really started to think the bacteria in my face is no where to be found except in me
Do you have lectures pdf for this??
THE BEST
I use clindamycine gel for acne. And make a pih left? Why?
Please do a video on antivirals
Can any one tell me the animation sir is using please
Good 👌
❤❤
I stopped using adapalene and my acne came back. What can I do now till I take my next dermatologist appointment ? Is there a way to stop them for a few days? Im not able to plan my dermat appointment because of busy schedule and cant risk having acne back coz I'll be having events next week.
How are you now?? Please update
@@rimisha162 still struggling with acne lol. My dermat gave me adapalene + bpo again now
Please make one for DMARDS
I would recommend this acne guide *AcneCureOnline. Com* to anyone who is suffering from discovering the right acne remedies on their own. Our family is suffering from acne since then and I have tried different acne treatments. Luckily, with the help of this impressive guide, acne was cured and development was halted. .
Can someone please help me with this question : Is the hormonal therapy part of this video only for females? Can males use spironolactone? Please let me know thank you so much. :)
I hve white comidones on my chiks whixh product i use on my fce my skin is to senstve n oily
zinc, vitamin a (retinol), vitamin b5
Is minocycline tablet good for acne?
Minocycline is often prescribed for acne.Whether it's appropriate option for you, it's something that you would have to discuss with your dermatologist.
These drugs are like a miracle yet SO expensive
Really? How much do you pay (and where are you from)?
THANKYOU THANKYOU THANKYOU
I really dont know what happen to me, I've acne since 14 yo but now suddenly it's getting worse, I even have acne in my head like in my scalp. I'm 20 yo now, and I dont know the caused of it 😭
hey do you still have acne its now have been 3 years to this comment now you are 23 i am same in youur condition i am 20 and still having lots of acne
@saurabhpanigrahi5429 hello, yes I still have acne but mostly caused by hormonal changes before my period and not as severe like those years ago. I actually not sure what made it dissapeared. Few things happen at them same time. I moved out to a different city (some people believe water and air can cause acne), I am no longer depressed, I drink some supplements, I go out more often (some people says sun is good for skin just not too much and always remember suncreen). I was actually almost free acne when I moved to different city. And then I move in with my parent again (it is so challenging to live with them) and my acne started to shows again despite still consuming the same supplements but not as worst as before (no acne on my scalp anymore). So I start using retinol, in my case it really help but make sure you use facial wash and moisturizer that already suit your skin because if not the retinol only would make the acne worst.
Mhm. So retinoids just unplug the follicle via pushing new cells from behind. Based on this I thought if you had psoriasis (which is characterized by quick maturation of keratinocytes) you would make everything worse if you used retinoids. I googled and I am wrong, actually it's even a treatment vs psoriasis. Anyone know why? Is it like a "restart" for the keratinocytes?
As far as I know the exact molecular mechanism by which retinoids are able to exert their effects on psoriasis is unknown. However, in psoriatic keratinocytes retinoids appear to produce antiproliferative effects, normalize abnormal differentiation, and decrease expression of inflammatory markers
@@SpeedPharmacology Awesome, thank you very much!
But they also speed up skin turnover, which seems beneficial for someone dealing with this skin disorder as it would help prevent the buildup of skin layers. (?). It also normalizes things, which would also be helpful for preventing psoriasis-I would think.
This is so good and informative. Great video, clear and aesthetically pleasing lol.. I wanted to know what I was putting on my face. I’m confident benzoyl peroxide/ doxycycline combo + tarazotene the dr prescribed along with healthy lifestyle changes for hormonal regulation (and prayer lol) will cure my acne! 🙏🏾