Excitation Contraction Coupling in SMOOTH Muscles || Its DIFFERENT than in Skeletal Muscle
HTML-код
- Опубликовано: 26 июл 2024
- 📝 All videos on Muscle Physiology: www.nonstopneuron.com/post/ph...
🌐 Explore our entire animation video library: www.nonstopneuron.com/
● Follow me at:
• Instagram: / nonstopneuron
• Facebook: / nonstopneuron
Excitation Contraction Coupling in Smooth Muscles:
The calcium for smooth muscle contraction, comes from extracellular fluid, as well as sarcoplasmic reticulum.
Inside the cell, the calcium binds with calmodulin, and then this calcium-calmodulin complex activates myosin light chain kinase.
This enzyme phosphorylates the regulatory light chain of myosin, which restore the ATPase activity of the myosin head.
This allows the myosin cross-bridge cycle, producing muscle contraction.
To reverse the process, the calcium is pumped back into the extracellular fluid, and sarcoplasmic reticulum.
This inactivates myosin light chain kinase.
And the phosphate from the regulatory light chain, is removed by myosin phosphatase.
Chapters:
00:00 Intro
00:19 Entry of Calcium in Cytoplasm
01:57 Calmodulin
02:23 Myosin Light Chain Kinase
03:01 Cross Bridge Cycle
03:30 Termination of Contraction
04:25 Summary
Dr Vipul Navadiya
DISCLAIMER: This video is for education purposes only. Although every effort is made to ensure the accuracy of the material, viewers should refer to the appropriate regulatory body/authorized websites, guidelines, and other suitable sources of information as deemed relevant and applicable. In view of the possibility of human error or changes in medical science, any person or organization involved in the preparation of this work accepts no responsibility for any errors or omissions, or results obtained from the use of information in this video.
![Cordae - Saturday Mornings (feat. Lil Wayne) [Official Music Video]](http://i.ytimg.com/vi/z2GYJua09F0/mqdefault.jpg)
best physiology channel right now
i love your original voicing so much🥺 this voice makes it sound so generic idk i just lose focus😂😂 nevertheless amazing videos, in my opinion the best physiology explanations especially with animations like its even the best animations. also i love summaries in the end of a video, best way to solidify the information or make sure i understood the topic. keep going man i wish u all the success💗💗💗
İ do agree. This voice distracts and too fast for this video. 😢
One of my happy moments when you upload a video.
Fabulous way of teaching ❤
Your explanations are really great and easy to understand, please do make more videos😄
Very nice 🎉❤
Excellent video ❤
l really thank you, sir ❤
Soooo helpful❤
Sir please upload a video on CARDIAC ARRHYTHMIAS too
Nice and creative 🥳
It's wonderful🌺🥺✨
Great job🌹
You are better than my professor😂😂
Thank you sir ☺
Thank you Sir
Very nice 💯💯💯 آفرین love from Persia
Very wonderful lecture, just like watching a movie, 🥳🥳
Thanks
Wonderful 🤍❄️
Thnku
Wow!!
Great video but aren’t the ip3 receptors in SR not the RR responsible for Ca+ release from SR?
Wao ♥️♥️
Thanks sooo much. + At the end, the myosin heads disassociate from the actin by ATP binding right!!
by ATP leaving the globular head not by ATP binding
👏🏻👏🏻👏🏻
❤❤❤
❤❤
👍💯
How do I externally influence the smooth muscles to contract? Do I ingest calcium? I’ve tried everything and still my bowel movements are pathetic.
Oats, prunes, walking an hour a day, reduce meat.
🙏
❤
Just like watching cartoon
why ca binds with a calmodulin specifically!? >>>to do his job, we are created for purpose >>>《Glory be to ALLAH the Creator, we do not own ourselves, nor by our will, nor by our control》
Thanks man🌹