Neural Conduction, Action Potential, and Synaptic Transmission
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- Опубликовано: 27 авг 2019
- We have probably heard that neurons are the cells that transmit information around the body. But how does this work? Is it actual electricity? Like from the wall socket? What is a synapse? What happens there, in between one neuron and the next? This is a really big and really important topic, so let's dive in.
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More understandable and efficient than reading 20 pages of my textbook :)
Sadly term exams gonna ask qn frm txtbook
Plese share the notes on neurotransmission
@@sreemohansharma5954 You're right about that. I wish we were tested on understanding, not what we can regurgitate from a textbook.
That's what it's all about!
@Sreemohan Sharma well at least now you can go through the material twice as fast (at least) and it'll be much easier to remember the key points and maybe even details! Just as long as you don't make excuses of course 😉
I love the fact that your vids are a good length at just under 20 minutes (so can keep your attention and focus) but feel like they're about 2 minutes long! Awesome stuff ;D
This is such a great video; explains everything so well, and leaves no leaps of faith! Love how you included how "chemistry happens in picoseconds". Thanks Dave!
Yeah, I loved that too, cuz I was wondering about it, like there’s so much going on in our neurons and signals travel all these distances like. I AM WOWED
I've been watching and reading a lot about this topic but nothing compares to your presentations. The sophisticated graphics alone must take countless hours to create, let alone all the research you must be doing for all your material. Pretty mind-boggling in and of itself! Thanks for the hard work. I'll be signing up and donating on Patreon in the near future.
Thanks Dave! Honestly this saved me. I have a practical on Monday and we are required to know pretty much everything you explained on action potential. This is great. THANK YOU!
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I literally just started learning this stuff this week. Great timing.
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Thank you so so much sir. I wish my professor could explain as clear as you did here. I've watched a lot of your videos before and they all helped me a lot.
This covers all of my questions. Perfect! I didn’t have to sit in class for hours.
Got a physiology exam in 2 days . 0 study done , watching a few vids of this guy can put me in a position where I can pass , shoutout to Professor Dave!!
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I want to add another comment, THIS IS SUCH A GREAT VIDEO!!! I understand the concepts different receptors but most times, I cannot picture the connection and how it happens (how it jumps from one type of receptor to the next). THANK YOU SO MUCH
This is the most helpful videoseries i've come across for understanding biopsychology. Thanks a lot!
Life saver !!! The explainations are so clear. Thanks so much for making this fab video
My biopsychology teacher took 1 week to clear this topic and you finished it in 20 minutes amazing 🤩😍
great piece of work, very detailed explanation and easier to understand, thanks alot Dr.
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Professor Dave!! Thanks so much!! your videos and explanations answer even the questions i can't articulate. And, you have great and memorable analogies which makes it a lot easier to understand and to keep up!!!
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omg of all videos, this is the most informative and easy to understand. i have weekly A&P Exam and this is our topic. Thank you so much!!!❤❤❤
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Very explicit and simple to understand. Thank you professor Dave.
Incredibly helpful, thank you proff.
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Came here from professor Dave's post. Good vid and more so interesting to an EE. "Oh electrochemistry, what will you come up with next..."
Thank you! This finally makes sense.
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Thankyou so much for making it easy and understandable 🙂
Nice understandable explanations. Thanks
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It was really helpful. For the first time neuro was easy for me to study.
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I am reading this in my biopsychology textbook right now, and I didn’t understand ANY of it until I watched this video.
thank you professor Dave!
nicely explained thanks
I'm really thankful.
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I was drinking water when 7:46 suddenly appeared lol
Another great video just when I needed it the most, thanks proffesor!
Thank you so much for making this video..... I even watched your muscular contraction video it made all my doubts clear...Great video
Thank you professor dave
Thank you for sharing
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Great explanation, I almost can relate to everything you said, lol so much information. Good thing that’s what our brain is for. To hold information.
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superb illustration
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I really like your videos even though I can’t understand everything bcz I’m not a native English speaker which makes it hard for me to get everything clearly .. but your videos still so helpful . I appreciate your efforts , thank you so much .
Turn on ur captions too :)
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Great video!
Finally undetood how action potential happen
Thank you so much ❤️
Thank you so much!! God bless you .
Great content! It might be worth updating at some point to reflect emerging sense that cimpressional/acoustic waves in lbl and cytoskeleton are also playing a role.
Thanks a bunch
May i ask when is the action potential generated? Surely if the neurotransmitter is inhibitory, it wpuldn't stimulate the voltage gated Na+ and K+ channels to open at all - so what would happen if the summation was overall hyperpolarising? Is this vid assuming the NT is excitatory? I would have guessed the action potential would be generated after the ionotropic channel reached threshold value but im unsure.
Liked this video after the intro played. Top notch intro. 7/7
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I'm not sure voltage-gated potassium channels opening at the depolarization threshold is accurate. It would have to move against both electrical potential and concentration gradients to make the intracellular potential more positive and literature seems to suggest that it is either calcium or more sodium gates
00:25 the signals don't go from hands to spinal cord and then to the brain?
It happens in milliseconds millions of times in every activity we do. And he took 15 minutes to explain its summary. Only one word.
Great teacher ❤️
And subhan Allah
great teacher is 2 words but i agree 😭😭😭
This is great! I was reading an article about electrophysiology, and I needed a quick refreshment of the matter. This helped a bunch! Super well explained!
Thanks💖
I've understood Prof Dave welcome Tanzania sir at Mt Kilimanjaro
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Prof. Dave, I want to thank you for your excellent work and the quality of your videos, which has helped many students who are currently in remote education. However, I believe that it is not offensive that I point out a flaw in the content: the sodium-potassium pump does not only turn on at the end of the action potential, but has intermittent activity and is more active in repolarization, as sodium is stimulating for its functioning ; refractory periods also do not occur after the end of repolarization, but at the moment that repolarization begins, since the absolute refractory is caused by the return of the sodium channels to the resting shape, and the relative refractory is due to the membrane's hypernegativity , and therefore would need an additional voltage to cause premature potential and action. Despite this small point.. it"s a very great job!!
Amazing
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Content of tremendous value, you often fill in the gaps of concepts I'm trying to understand.
I think one point could be made more clear in this video. Based on most other sources I have, voltage-gated sodium channels only start opening quickly at around -55mV (threshold value) and voltage-gated potassium channels at around +30mV. But, for example in the figure at 10:50, you show and say the potassium channels open at -55mV. I'm trying to get this clear for myself, so maybe this is of help! I'd also like to suggest a video about saltatory condunction in detail! :D
On God no Cap you right
So far 3 videos said to watch another video I should have already watched ! 😊 ok so can you start numbering your videos ??? Please I love your show
everything is organized nicely into playlists, go to my home page and see.
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is there a transcript of this?
Can anyone tell me what is the need for action potential? Does it help in faster transmission of the nerve impulses?
The action potential itself IS the achievement of electrical transmission-that is, once the neuron reaches its threshold potential, sodium ions will rush in, leading to a rapid transmission of an electrochemical impulse down the axon. It certainly helps the speed of transmission-as does the myelination of those axons, which insulated the signal and makes it go faster, similar to wires in our homes.
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I thought that
resting state: Na and K gates closed.
depolarization phase: Na gates open but K gates still closed
repolarization phase: Na gates close and K gates open
Then the Na/K pump: brings in back from hyperpolarization to RMP??????? That's how my professor taught it...is it wrong?
What if ions come under the influence of gravity?? Potassium ions being heavier than sodium will fall down through inner membrain so the concentration gradient might change with In the inner membrane itself. Can you kindly clear my doubt??
We are talking about an amount of mass that is totally negligible. Gravity does not dictate events on the molecular level.
What happens between the membranes ? And why certain diseases which thickens membrane makes slower signaling ?
Between which membranes? I'm not aware of anything that thickens membranes, I would assume they are of fixed width, as phospholipids are of a fixed length.
@@ProfessorDaveExplains At ruclips.net/video/zHJ3h675nNk/видео.html I can see several membranes/coath, where in-between is a thick area. Or this is just a symbolic image and membrane is thru the whole axon in one piece ?
As matter membrane thick, there are several demyelination processes regarding neuro diseases (multiple sclerosis, gulian-barre syndrome etc..)
@@aleshiukas the demyelination would denature both the protein and membrane layers along the mylin sheath layers which would rupture the tissue, therefor affecting the action potential of the cells, and reducing cognitive ability. but all of this if one were to state it the way your trying to understand it, is technically DECREASING the density or thickness of the sheath.
I am not aware of increases in neuron growth as neuronal cells are stagnant and do not replicate. If they do it is very rare and through the use of extensive oxygen induction.
@@fernsader9261 Im asking why demyelination slows down messages sent along axon comparing the healthy nerve with a normal myelin coath.
I come ere when I can’t be asked to read the textbooks although I still end up reading it because I learn best from multiple sources with the same ideologies 😃
Sir we loved the old hairstyle.😁
Awesome explanation though.
Where’s the neurotransmitter video? Was it ever made?
i would fail my course without this..