Gaint Cell Tumor Of Bone | Histopathology | Gross | Cut Section | Microscopy | Pathology

A giant cell tumor of bone is a type of benign (noncancerous) tumor that has a wide range of behaviors. These tumors typically grow at the ends of the body's long bones. Most often, they appear at the lower end of the femur (thighbone) or upper end of the tibia (shinbone), close to the knee joint.
Giant cell tumors usually occur in young adults, and are slightly more common in females. They are quite rare, occurring in only about one out of every one million people per year.
Although giant cell tumors are not cancerous, they are aggressive and can destroy the surrounding bone. Treatment for a giant cell tumor almost always involves surgery to remove the tumor and prevent damage to the bone near the affected joint.
Most often, the tumors occur close to the knee joint-either in the lower end of the thighbone (femur) or the upper end of the shinbone (tibia).
Other common locations include the:
Wrist (lower end of the lower arm bone)
Hip (upper end of the thighbone)
Shoulder (upper end of the upper arm bone)
Lower back (connection of the spine and pelvis)
In rare cases, a patient can have multiple giant cell tumors in different bones, a condition called "multi-centric giant cell tumor of bone."

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