Thanks for the video, Dave. I appreciate how you start off by explaining the basics and then go into applying the concept through examples. I find this method very useful when learning. I'm using a lot of your videos for my organic chemistry courses. Thanks again!
I agree. Awesome vid with helpful examples, Professor Dave! By the way, ChemSimplied, I checked out your channel, you've got something good going on there too. Helps with my Gen Chem. Thanks, both of you!
How do we know from what angle should we look at the structure and then determine what is pointing outwards and what is pointing inwards? What is it that made you look at one structure from the angle BD and at the other structure you looked from above (first part of the video)
I was wondering when assigning the priority of 2nd or 3rd, the differing point would be for example a carbon in a benzene ring (sum of atomic numbers of bound atoms would be 18 in total with the carbon double bond plus another carbon bond) vs a carbon bound to oxygen, carbon and hydrogen (giving a total atomic number of 13). Why is it that the carbon in the benzene ring is assigned a lower priority? (this is seen in S,S-Reboxetine)
3:42 " we got the OH to the left which would be the dash..." All horizontal ones are wedges so why would the left one be a dash? all OHs are pointing towards us since we are looking at the fisher from the point of the plane of the board i.e from above. Maybe I don't remember my orgo properly but I m fairly sure that the left OH is not a dash (unless you mean that the chain is looked from the side then that left OH is seen as a dash). If you look at the last drawing from the top as the eye shows then that OH should be wedge. It is only dash if you look at the fisher from lets say a 4 o'clock position...or am I derping
In that section I am translating the Fischer projection to line notation. Looking directly at the Fischer projection is being translated to a perspective that is within the plane of the board. If you're in the board facing rightwards on the board, groups to your left are on dashes, groups to your right are on wedges.
@@ProfessorDaveExplains I just wanted to point that out because for students that are just learning about it they hear that in fisher when groups are horizontal they are wedges and then 2 mins later they are told that a horizontal group is a dash. I recognized that this was from the perspective of being to the right looking at the molecule but 1st year orgo student would not...just needed to clarify that :)
i love watching your videos, they are short but clear and well articulate and plenty of examples to demonstrate the main point.....but what happened to your hair?!!!! you had that totally hippie professor look, you still look good but i miss the hair :D
It seems so random though, how do you choose certain OH's to be dashes and certain ones to be wedges. Also how do you know which H's will become dashes and wedges in such a long Fischer projection
unfortunately examples used are only the easiest possible examples, and then there are no examples with multiple stereocenters in a row on a Fischer projection... maybe try to do the easy examples and then upgrade to less easy examples like on a 3 or 4 carbon chain Fischer projection
Hey Professor Dave... So I wanted to tell you something I learnt just recently, and it just confuses me a lot! So in school, we were taught to neglect the heaviest atom and then to rotate the molecule to get the H atom to be positioned to the front (such that its facing us). I dunno why, but I always get the wrong answer, after following the school method. Could you pls help me clear my doubt. Thank you for this video btw
![Summer Walker - Heart Of A Woman [Official Lyric Video]](http://i.ytimg.com/vi/SFddctbZzw8/mqdefault.jpg)
Here I am, six years later studying orgo from the same guy that taught me chem back in high school.. God Bless Professor Dave.
This is in high school
same here, it is crazy lol
Thanks for the video, Dave. I appreciate how you start off by explaining the basics and then go into applying the concept through examples. I find this method very useful when learning. I'm using a lot of your videos for my organic chemistry courses. Thanks again!
I agree. Awesome vid with helpful examples, Professor Dave! By the way, ChemSimplied, I checked out your channel, you've got something good going on there too. Helps with my Gen Chem. Thanks, both of you!
I don't understand, How in the name of science can a rational human being dislike this video? YOU ARE THE BEST PROFESSOR DAVE!
I FUCKING LOVE YOU, i HAVE MY ORGO FINAL IN 50 MINUTES - YOU LITERALLY EXPLAINED IT PERFECTLY, I LOOOOOOOOOOOOOOOOOOVE YOOOOOOOOOOOOOOOOOOOOOOOU
I see you making new videos. Your O-Chem videos are the best.
Damn I'm taking biochemistry now and neither my professor or my book went into depth about Fischer projections. They were just given to us. Thanks!
This man is the only reason I am passing all my chemistry classes. Thanks Dave!!!
You taught so well...
🤩
I was literally assuming things to assign S and R ...
But coz of you ... Now I can do it correctly 💗
you're the sole reason i'm gonna pass my org chem this weekend.
This is what we call ladies and gentlemen; a $ video. Clean asf and articulate
How do we know from what angle should we look at the structure and then determine what is pointing outwards and what is pointing inwards? What is it that made you look at one structure from the angle BD and at the other structure you looked from above (first part of the video)
goodness.........this was one of the best expnation so far.........thanks a lot for sharing
I was wondering when assigning the priority of 2nd or 3rd, the differing point would be for example a carbon in a benzene ring (sum of atomic numbers of bound atoms would be 18 in total with the carbon double bond plus another carbon bond) vs a carbon bound to oxygen, carbon and hydrogen (giving a total atomic number of 13). Why is it that the carbon in the benzene ring is assigned a lower priority? (this is seen in S,S-Reboxetine)
Thank you Professor Dave, you're my savior!
3:42 " we got the OH to the left which would be the dash..." All horizontal ones are wedges so why would the left one be a dash? all OHs are pointing towards us since we are looking at the fisher from the point of the plane of the board i.e from above. Maybe I don't remember my orgo properly but I m fairly sure that the left OH is not a dash (unless you mean that the chain is looked from the side then that left OH is seen as a dash). If you look at the last drawing from the top as the eye shows then that OH should be wedge. It is only dash if you look at the fisher from lets say a 4 o'clock position...or am I derping
In that section I am translating the Fischer projection to line notation. Looking directly at the Fischer projection is being translated to a perspective that is within the plane of the board. If you're in the board facing rightwards on the board, groups to your left are on dashes, groups to your right are on wedges.
@@ProfessorDaveExplains I just wanted to point that out because for students that are just learning about it they hear that in fisher when groups are horizontal they are wedges and then 2 mins later they are told that a horizontal group is a dash. I recognized that this was from the perspective of being to the right looking at the molecule but 1st year orgo student would not...just needed to clarify that :)
i love watching your videos, they are short but clear and well articulate and plenty of examples to demonstrate the main point.....but what happened to your hair?!!!! you had that totally hippie professor look, you still look good but i miss the hair :D
Thank you for the assistance!
Good teaching
I just had my chem midterm literally yesterday, damn
Erin same! mine was a week or so ago smh lol
Thanks a ton!
you are amazing
I am a big fan of you sir
It seems so random though, how do you choose certain OH's to be dashes and certain ones to be wedges. Also how do you know which H's will become dashes and wedges in such a long Fischer projection
I have the exact same question
Good teaching.
could you please explain how to draw fisher projections?
thankyou 💖
Best teach!
brilliant
Zeezamezine and bow tie helps!
3:50 Are you sure you didn't draw the mirrored version of this fischer projection?
hi Dave
4-O-acetil-D-galactosa i need the fischer structure
unfortunately examples used are only the easiest possible examples, and then there are no examples with multiple stereocenters in a row on a Fischer projection... maybe try to do the easy examples and then upgrade to less easy examples like on a 3 or 4 carbon chain Fischer projection
Damn i cant thank you enough for these!!Great job!
Hey Professor Dave...
So I wanted to tell you something I learnt just recently, and it just confuses me a lot!
So in school, we were taught to neglect the heaviest atom and then to rotate the molecule to get the H atom to be positioned to the front (such that its facing us). I dunno why, but I always get the wrong answer, after following the school method. Could you pls help me clear my doubt.
Thank you for this video btw
well that would be because that's the opposite of what you're supposed to do! the lowest priority group has to be facing away from you.
sankyou
wow
GOAT
You reading the comments, study!
AJ
First
Me : first to reply your comment
U cut your hair men