Thank you so much for your videos. My Siggy, is the st Cav I have had and it was frightening the day he started screaming in pain and had to be rushed to ER. The thought he had a slipped disk but late a neurologist conformed he through an MRI he does have CM and SM. It's been a battle with meds and other issues making us shift meds around. He was on Gabapentin but he no longer is and he was on 5mg Prednisone but that was reduced to 1 MG. So very small dosage. We tried getting him off of that because he was getting so bloated but the fantom ear scratching thing got bad so we are getting him back in the 1 MG a 1x a day for a week then every other day. he also takes 5 MG Omeprazole. It's rough knowing he may be in pain and if we are doing enough. I never want to hear that screaming in pain again. That was such a heartbreaking and frightening thing. This condition makes us feel pretty helpless. You videos at least help us feel a better informed on our options.
I want to thank you so much for this beautiful presentation... I am so grateful that one of you genius' has found a way to spell this out in laymen's terms..... I am currently fighting off any signs of suffering in my 13 year old Cav with gabapentine prednisone, prilosec, and CBD. As well as treating her heart murmur with cardiac meds.... I refuse to allow her or any of my sweet pups suffer but the comfort measures can only take us so far before we need to make a hard decision...
Chiari Check chiari-check.surrey.ac.uk/ PDF of the treatment algorithm veterinary-neurologist.co.uk/cmsm-new-treatment-algorithm-2024/ or www.cavaliermatters.org/professor-clare-rusbridge-cm-sm-treatment-plan-2024/?fbclid=IwAR0nG6R3zifHZc7fLTLe0b5hcDiTr9QllWFxUL_qLEShOfG6ilZfoi8Dk0E
No strong evidence for mineral and vitamin supplement - this was recently reviewed in human medicine (neuropathic pain) here DOI: 10.1111/papr.13291 and the conclusion was " Based on the review, we cannot recommend any supplement (for chemotherapy induced peripheral neuropathy)....although further research into N-acetyl-cysteine, l-carnosine, crocin, and magnesium is warranted....... Studies with goshajinkigan, vitamin B12, vitamin E, and glutamine had conflicting results regarding efficacy, with one goshajinkigan study finding it harmful. Guilongtonluofang, ninjin'yoeito, and antioxidants showed various degrees of potential effectiveness. Regarding diabetic peripheral neuropathy our review supports the use of alpha-lipoic acid, acetyl-l-carnitine, and vitamin D.... Check out my video on PEA which is the supplement most commonly given to dogs with neuropathic pain.ruclips.net/video/MQQJzhT8yxY/видео.htmlsi=gUvfOJrDq32wj6QL
Not to sure of the context here - i.e. whether you should think that I should never mention PEA or that you think that PEA should have been mentioned more! However for the record, PEA was mentioned briefly, at least in the slides, and those interested were referred to an entire dedicated video here ruclips.net/video/MQQJzhT8yxY/видео.htmlsi=WZDwNlzF5ipOxzAT which discussed pros, cons and the available scientific evidence. As there is not YET any evidence of effectiveness of PEA for neuropathic pain in dogs or cats and it is an expensive supplement which in some forms does not even get into the animal's body then it cannot be in a treatment algorithm because this has to be based on best available evidence - especially when this disease causes such a welfare problem. Hope that helps
A huge amount of work involved that will help many hundreds of dogs with these conditions - well done Clare
My little Maltese just went for an MRI for a slipped disc & they discovered he has this 😢 hopefully picking him up later today.
Thank you so much for your videos. My Siggy, is the st Cav I have had and it was frightening the day he started screaming in pain and had to be rushed to ER. The thought he had a slipped disk but late a neurologist conformed he through an MRI he does have CM and SM. It's been a battle with meds and other issues making us shift meds around. He was on Gabapentin but he no longer is and he was on 5mg Prednisone but that was reduced to 1 MG. So very small dosage. We tried getting him off of that because he was getting so bloated but the fantom ear scratching thing got bad so we are getting him back in the 1 MG a 1x a day for a week then every other day. he also takes 5 MG Omeprazole. It's rough knowing he may be in pain and if we are doing enough. I never want to hear that screaming in pain again. That was such a heartbreaking and frightening thing. This condition makes us feel pretty helpless. You videos at least help us feel a better informed on our options.
thank you for your kind comments- I am so glad that they are useful
I want to thank you so much for this beautiful presentation... I am so grateful that one of you genius' has found a way to spell this out in laymen's terms..... I am currently fighting off any signs of suffering in my 13 year old Cav with gabapentine prednisone, prilosec, and CBD. As well as treating her heart murmur with cardiac meds.... I refuse to allow her or any of my sweet pups suffer but the comfort measures can only take us so far before we need to make a hard decision...
sorry to hear about your pup! - i hope that the video has helped refine her treatment
@@clare-neurovet Thank you again! I have rewatched your video 2 more times (taking notes!) Do you know if the heat exacerbates their discomfort?
@@Katiekay. yes (anecdotally) and rapid changes in air pressure - if you are in the south east England then this weather we are having now is not good
Your videos look like they are from the future.Amazing.🙂
thank you so much - very kind of you- I have learnt a lot in the last 3 months! (and spent too much money getting equipment LOL 🤣😂🤣😂
Thank you Clare - Very informative and clear.
Chiari Check chiari-check.surrey.ac.uk/
PDF of the treatment algorithm veterinary-neurologist.co.uk/cmsm-new-treatment-algorithm-2024/
or
www.cavaliermatters.org/professor-clare-rusbridge-cm-sm-treatment-plan-2024/?fbclid=IwAR0nG6R3zifHZc7fLTLe0b5hcDiTr9QllWFxUL_qLEShOfG6ilZfoi8Dk0E
Love these videos. Is there any research to suggest vitamin and mineral supplementation alongside prescription drugs to be helpful in reducing pain?
No strong evidence for mineral and vitamin supplement - this was recently reviewed in human medicine (neuropathic pain) here DOI: 10.1111/papr.13291 and the conclusion was " Based on the review, we cannot recommend any supplement (for chemotherapy induced peripheral neuropathy)....although further research into N-acetyl-cysteine, l-carnosine, crocin, and magnesium is warranted....... Studies with goshajinkigan, vitamin B12, vitamin E, and glutamine had conflicting results regarding efficacy, with one goshajinkigan study finding it harmful. Guilongtonluofang, ninjin'yoeito, and antioxidants showed various degrees of potential effectiveness. Regarding diabetic peripheral neuropathy our review supports the use of alpha-lipoic acid, acetyl-l-carnitine, and vitamin D.... Check out my video on PEA which is the supplement most commonly given to dogs with neuropathic pain.ruclips.net/video/MQQJzhT8yxY/видео.htmlsi=gUvfOJrDq32wj6QL
Very useful video！ The NSAID drug you mentioned in the video, is called "grappa print"? can you tell me the right name plz？
So glad you found it useful - Grapiprant - more info about NSAIDS here ruclips.net/video/Zc-mTHBDRSY/видео.html
Wow! Never mention PEA
Not to sure of the context here - i.e. whether you should think that I should never mention PEA or that you think that PEA should have been mentioned more! However for the record, PEA was mentioned briefly, at least in the slides, and those interested were referred to an entire dedicated video here ruclips.net/video/MQQJzhT8yxY/видео.htmlsi=WZDwNlzF5ipOxzAT which discussed pros, cons and the available scientific evidence. As there is not YET any evidence of effectiveness of PEA for neuropathic pain in dogs or cats and it is an expensive supplement which in some forms does not even get into the animal's body then it cannot be in a treatment algorithm because this has to be based on best available evidence - especially when this disease causes such a welfare problem. Hope that helps