Methylene Blue and Near Infrared Light for Neuroprotection
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- Опубликовано: 23 ноя 2022
- Studies show that neurons are metabolically protected when low dose Methylene Blue is administered systemically. Methylene Blue promotes energy metabolism and neuronal survival. A similar protective effect is observed with near infrared light. Let's review.
DrBeen: Medical Education Online
www.drbeen.com/
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References
URL list from Thursday, Nov. 10 2022
Frontiers | Protection against neurodegeneration with low-dose methylene blue and near-infrared light
www.frontiersin.org/articles/...
Methylene Blue Reduces Acute Cerebral Ischemic Injury via the Induction of Mitophagy | Molecular Medicine | Full Text
molmed.biomedcentral.com/arti...
Effect of Methylene Blue on White Matter Injury after Ischemic Stroke - PMC
www.ncbi.nlm.nih.gov/pmc/arti...
Repurposing methylene blue in the management of COVID-19: Mechanistic aspects and clinical investigations - PMC
www.ncbi.nlm.nih.gov/pmc/arti...
Frontiers | Methylene Blue Reduces Neuronal Apoptosis and Improves Blood-Brain Barrier Integrity After Traumatic Brain Injury
www.frontiersin.org/articles/...
Addressing Personal Protective Equipment (PPE) Decontamination: Methylene Blue and Light Inactivates SARS-CoV-2 on N95 Respirators and Masks with Maintenance of Integrity and Fit | medRxiv
www.medrxiv.org/content/10.11...
Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation
translationalneurodegeneratio...
Photobiomodulation as a treatment for neurodegenerative disorders: current and future trends - PMC
www.ncbi.nlm.nih.gov/pmc/arti...
Shining light on the head: Photobiomodulation for brain disorders - PMC
www.ncbi.nlm.nih.gov/pmc/arti...
Nitric Oxide, Cytochrome C Oxidase, and the Cellular Response to Hypoxia | Arteriosclerosis, Thrombosis, and Vascular Biology
www.ahajournals.org/doi/10.11...
Mitochondrial electron transport chain, ROS generation and uncoupling (Review)
www.spandidos-publications.co....
Frontiers | Mitochondrial Reactive Oxygen Species and Their Contribution in Chronic Kidney Disease Progression Through Oxidative Stress
www.frontiersin.org/articles/....
Mitochondria-Fundamental to Life and Health - PMC
www.ncbi.nlm.nih.gov/pmc/arti...
After Treatment with Methylene Blue is Effective against Delayed Encephalopathy after Acute Carbon Monoxide Poisoning - PubMed
pubmed.ncbi.nlm.nih.gov/29151...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
I learned the Krebs cycle in Chem A, Professor Berkan used 'happy bachelors' i his drawings. Then, it came up in Biochemistry, I already knew it! Then it cam up in Nursing school, I already knew it! Then it came up in Organic Chemistry in Pre Med, yeah on top of that! Now here it is again, demonstrating the value of education and excellent teachers! Dr. Been is an excellent teacher people!
AVOID MB TEETH STAINS: after putting MB into water, add Vit C powder and wait a few minutes until the water turns clear. No more Stains!! 🤗😁
Which Vit C do you use?
@@apacur normally natural factors brand but any brand of ascorbic acid shd do it.
The vitamin C oxidizes the MB so it will no longer have a therapeutic effect.
@@apacur usually Natural Factors
@@Krunch2020 Not so, within 4 days of taking only 8 drops in 2 cups water with vita c in it, I was suddenly playing ballistic tennis, hitting aces and outlasting good gal players in their 20s who wanted to quit after 3 sets, i dragged them on to finish 5 sets, then i wanted to play more!! and im almost 70!!
Thank you Dr Been. I started taking MB to ensure cognitive health. My sister has been on SSRI’s for over 30 years. She also has stage 3 kidney disease (for over 9 years with no improvement) caused by other meds she had been on. She got off her SSRI and started MB, 10 mg a day. She never felt better. Her doc was worried and made her get a blood test to see how her kidneys were dealing with MB. He was shocked to see her score improved 10 points after being on MB for only 1 month.
This video is a “must see” for everyone to understand the mechanism for cellular death and the life-saving potential for methylene blue and Near Infrared light.
This is absolutely the best explanation of mitochondrial functions I've ever seen. Kudos!
Started MB 2 weeks ago for JJ vax autoimmune phenomenon injury ongoing 19 months. I’m combining with far infrared/red light because that’s what I have available. I’ll be waiting with baited breath to hear more of what you have to say. Thank you for this topic and everything you do for mankind.
How much MB do you take? Where did you buy the MB?
1st make sure it’s pharmaceutical grade and comes from reputable lab. You can buy online directly from a couple companies or Amazon as long as reputable. I started with .50ml = 1 drop twice per day in water. Moved up to 2 drops twice daily then 4. Low dose is best. Before sauna, I started putting 2 drops under tongue for sublingual route. I’m dealing with autoimmune vax injury of 19 mo and pretty bad off so not sure if helping yet. I’ve had no issue with blue mouth BTW. Brand I’m using BPH MB 1% USP grade. Biopharm inc Arkansas.
Same issue for me & same timeframe 1st P - is the infrared helping?
Sauna does help greatly! Autoimmune phenomenon by the vax caused blood pressure, nerve and muscle pain which infrared has helped. It was either spend $ on medical bills or put it towards an at home sauna.
Are you finding any differences yet using this protocol? I’m going to start for my long haul tomorrow
Fascinating discussion! People who are on SSIRs antidepressants should bear in mind that Methylene blue is a Monoamine oxidase inhibitor (MAOI). MAOI inhibitors are known to cause serotonin toxicity when administered with selective serotonin reuptake inhibitors (SSRI).
Ohhhh. I’m on Zoloft. Thanks for this!
People on antidepressants should know the Serotonin theory of depression is officially dead. As of 2022 there is no evidence to support the use of SSRIs in anyone for depression. It is now known a small percentage have placebo effects, that's all. Serotonin levels have little correlation to depression. Big Pharma made 400 Billion in profits, but they don't work. Sound familiar? The original Pfizer vaccines .
@@trevorjohnson8653 yeah I heard that!!! I’m not on it for depression though.. it definitely doesn’t help with that tho imo. They’re still writing out those scripts now more than ever
The Mayo Clinic doctors disagree on this concern.
Fascinating! How carefully and wonderfully we were created!
Einstein said don't make things simpler but as simple as possible and you have reached to that level. A lay man like me, not related with medical science, understood the mechanism. Very nice and informative and will help me to maintain brain health . God bless you !
Those molecule cartoons really helped a mind like mind understand biochemistry.
Thanks for doing this.
I believe this will have implications for patients with ME/CFS as well. I have been responding well to red light therapy and it has improved the dementia in my elderly dog. The improvement has been noticeable. Haven't tried methylene blue yet, but I am going to. Thank you Dr. Bean.
It is NOT RED light!
F genius
One of the best doctors on RUclips who can explain in an easy and genuine way. I really appreciate all your works Dr Been.
Shukran Prf. Marandi and Kevork .
Thank you so much, Dr. Been! You are such a gift to this world.
Outstanding clarity. Thank you so much.
I wish I had you as a professor when I took undergrad Biochemestry 40 years ago. Amazing synthesis and delivery. Thank you Dr Been.
So much appreciation to this Dr. Subscribed.
Thank you Dr. Mobeen! I have been waiting for this and hoping your good brain could explain all the data! Thanks so much!
Thank you for all the work you put into your videos. I have learned much.
Excellent and very well presented. I have been following Dr Lima work as well. Much appreciated x
Thanks this video has increased my understanding of the biochemistry involved in the electron transport chain. This is an excellent thing as I am experimenting with low-dose mythalene blue for my own health enhancement. But more importantly, I eventually wish to get my wife to start using it as she has early onset dementia at 60 years of age.
Fantastic how it all works .. brilliant explanation. Thank you.
So we’ll articulated. So clear. Love the style of the illustrations. I couldn’t appreciate this video more.
Excellent clear and understandable explanation! You are an excellent educator deepest thanks for your sharing!😊
Amazing… well done on the hard work to produce the video, great explanation… ❤
U have such eloquence and intelligence. This was the best!!!!! U should surpass 2M followers soon
the best explanation I could find on the topic.
Thank you Dr. Been and Dr. Paul Marik ! Very informative..... Your knowledge is immense !!!!!!!!!!
Great lecture! Again Dr. Mobeen is rock star!
I have to mention one thing: you are doing so great presentations and you also explain the content very good🙏🏼👍🏼👍🏼
What a wonderful video, thank you very much!
Very clear. Informative. Not too fast and undecipherable as many other speakers of medical subjects. Congrats.
An amazing lecture. Thank you.
Excellent presentation indeed
Excellent presentation, and I can't wait to see the continuation of the Methylene Blue benefits.
As per usual... an outstanding presentation!
Excellent presentation.
Outstanding presentation! Clear and concise, the best I have ever seen. Thankyou!
Wow! Really nice education on the cell function. I learned so much.
one of the best explanations I have come across. Love the potato like ETC complexes. Been using MB for a year with NIR as a biohack for performance/longevity
OMG!!! Finally, something that makes since. God bless you Doctor Been. I have been suffering from the Delta variant since July 2021. Im about to lose my job of 16yrs. I was already giving up. Thank you! I don’t even know what else to try. Will hv to listen to this video probably 5 times to be able to process & figure out where to go here in California- West Hills. You are a true doctor!!!! I have subscribed & more.
Go low carb, intermittent fasting, stay hydrated, get sunshine, vitamin D, NAC, NAD, red light therapy, sauna therapy, breath therapy, stretch, sleep, the list goes on…
You are such a good teacher. Please keep these coming.
Incredible explanation. Thank you.
Wow Dr.Been. You’ve been my favorite guru since Covid started and you have changed my health. You are a genius and I am so grateful to have found your amazing teachings❤
Thank you! You are the best teacher to explain complex issues! I will buy some methylene blue, and try it!
Dr.Been 's drawings are very fascinating. Thank you for your work.
He pays artist. When he tries himself on live is terrible.
Best description I have ever heard on how MB really works. I feel like I understand the Krebs cycle better now! Thank you!
This was most interesting and educational. Thank you for the effort.
Thank you - Excellent simplified explanation of complex processes.
Very good presentation of the ETC and the Krebs Cycle. Well done. Thank You! I endorse both MB and PBM.
Outstanding explanation Dr! You ought to have Dr Lima on soon.
Absolutely the BEST VIDEO EVER!
Very excellent work!
Wow! Thank you so much for this very well done video! MB is just incredible too.
Very clearly explained and demonstrated. Thank you so much Dr Been. Will share this hugely helpful video and clear explanation of mitochondria oxidative phosphorylation, ATP, Nitric oxide, the complexes, etc etc. Womderful❗️🙏🤗
Awesome video. Thank you so much.
Thank you Dr. you are awesome!
Thank you! 😉 👍
It all sounds good, but remember, all chemical medications will have side effects. People have some significant adverse reactions to MB.
And don't forget some doctors recommend fluvoxamine for long covid, which is a mystery to me, because SSRIs can send certain people to hospitals from awful psychotropic reactions. Further, anyone wanting to take MB for covid should not take it with fluvoxamine (an SSRI)
Very informative lecture. Thank you!
Thank you Dr very much, I have to study this for my exams, you helped simply and make commonsense of this complex subject, thank you sir.
Thank you for this information lecture.
VERY interesting, THANKS!
Excellent lecturer
😱 thank you for the info Dr
Very excellent ..! Thank you for this explanation..!! 💕💕💕
I have used PBMT, principally Near Infrared Light, for several years and it is very effective in most cases, particularly where you get the dosage right by reading high quality studies. MB is new to me but I recently read where hospitals and dental clinics are combining either 405 nm violet light with MB (dental applications) or Near Infrared Light (around 810 nm or upwards) with MB to reduce post-surgical infections, particularly in medical environments having problems with ineffective antibiotics. I am now very interested to study the relationship between the light and the MB as I used to think MB was used only to give the light an external chromophore in the case of a virus infection (bacteria have internal chromophores so no MB may be needed). Anyway, I am being chatty because of excitement of seeing one of the best and most easily understandable lectures ever presented on these subjects by this remarkable speaker. I am subscribed and I will watch all of the videos.
I think it's pronounced "jewels" 30:20 not jowls
LOL, Christmas Story - _"You'll burn a hole in your head!"_
Quick as a wink, the PINK's in the sink. 36:00
Please take care everybody!
Brilliant explanation 🙏🏻
You make the best explanations 🙌
Thank you.
Q: Are PBM & MB redundant or can they be used in tandem? I experiment with both and, frankly, MB's WAY easier (no LEDs to burn out, lol). I'm in awe at your video, sir. EXTREMELY happy to have seen it. Interesting way to explain, friendly & clear drawings... Hugs from Brazil🇧🇷!
Thank you very much,it's super!
Thank you for sharing your knowledge. Some of it went over my head but overall I am very interested and excited to try MB. If it can do half of what people claim then sign me up..
excellent thanks.
you quickly mention lots of enzymes in the christae, any link to more complete discussion of this?
Superb Presentation and beautifully illustrated
This is very exciting. My doc doesnt seem to be able to help with my low sats as they are too borderline for me to be referred to a long covid clinic and my tachycardia and bradycardia arent considered connected, and im down for refusing beta blockers (a sensible med if youre a bit bradycardic..??? I think not!) Anyway im obviously 9nmmy own with this so ive got to work out a treatment for myself so ill try methyle blue, and as i have a near infrared lamp i might as well use it too! So grateful for the resources you can find onYT, and grateful thanks in particular to Dr Been 🙏
Best explanation of how the mitochondria functions that I have ever seen!
QQQ Is MB naturally occurring in the body?
It is not
A good scientific explanation of why methylene blue and near infra red light therapies can be very beneficial to our mitochondria and our overall health. I take MB several times a week, and could take more according to your ideas of dosage. I have not tried RLT or NIRLT but they are worth investigating further.
what would be a time protocol for the red light therapy beds? Great video.
4 drops a day is my max, mixed in water I sip all day. More then that seem to over stimulate my muscles.
very interesting.
I had to write a comment and subscribe, such detail and passion for the subject was inspiring. Thank you, I learrnt a lot. What about the adverse effects of MB?
The only thing Ive heard is headaches if you take too much start low n work your way up according to your body weight but it helps with so many good brain functions and possibly add some MCT oi in your coffee or teal Ive heard the combination of redlight thereapy and MB has a lot of positives for brain fog dementia even Parkinsons.
Thank you for this discussion. Can you please help me identify/transfer discussed dosage into ml? how many ml per kg?
Who is this intelligent man
this has something to do with chrionic fatigue syndrome, something brakes down in this cell mechonism
I was prescribed cipro for diverticulitis around 5 times and the last time I ended up in the ER with severe dehydration. They had to give me IV minerals. I think my mitochondria are damaged by the drug as I still struggle with my hydration levels 3 years later. I hope MB helps. Now thinking of adding red light therapy as well.
Thank you so much for your report❤️
MB+NIR therapy seems like it might be an effective treatment for Seasonal Affective Disorder
As for determining "low dose" low-level near-infrared, it was quite involved. For the layman, how far would you place a 100W near-infrared bulb from your forehead to obtain this proper "forehead transcranial stimulation"?
That's deep ❤
Excellent explanation, very thorough! However, you said when talking about the lower dosage, that he would address that later… What would be considered a low dose, or safe dose? Does it vary between individuals? Thank you :-)
At 29:20, the text displayed states that 0.5 - 4.0 mg/kg (that's of body weight) is considered a low dose.
I've been trying to find information (that I can understand) about taking NADH and MB? I'm reluctant to take them on the same day. I haven't come across anything that states a negative interaction with NADH, however, there are medical papers on the effects of MB and NAD/NADH. Just wondering if anyone has an answer for me. Thanks.
Dr. Is there a way to create a symbiotic relationship between MB and Nitric Oxide? I have read many articles on each but seems some articles speak badly of NO. Yet, I can see the value NO brings to vasodialation. Can I create the same effects Nitric Oxide offers, by just setting a prescribed amount, frequency and dosage of MB to accomplish the same?
I read many articles on the benefits of NO, as well as MB. But occasionally, Dr's speak adversely about NO.
Can I get your input?
Thank you.
Are you taking it Dr? If so, what is your protocol?.0
do you have information how methylene blue and NIR can assist for multiple sclerosis
An excellent biochemistry lecture. Thanks
Methylene blue though, also inhibits nitric oxide of which we are already deficient as we age , but that at high doses No is oxidative, older adults don’t want to take out more No because they’re already too low in it , we need the two, but how do you balance it out ?
(Complex4) x? Great info❤
Love it 🔥
What about those who cannot make myophosphorylase?
Thank you, DrBeen. With this kind of information, I have hope that my daughter, a smart, beautiful senior in high school, can be healthy again. Trying so hard to learn quickly and take proper action that will help her before more muscle and brain damage occurs. Her symptoms are all over the place... gastro, neural, muscular. The cascading avalanche is shocking. To go from healthy, strong, enthusiastic to. weak, shrinking, pain ridden, and sad so, so quickly... (not c vaccinated, but similar vaccine 'storm' six years ago ar twelve years old, that stopped in thrre weeks. Thus one isn't!).
From gardasil? I have 4 daughters and we’ve been hesitant to get it for them
@@ericjohnson624 She had a flu shot. First one, and last one, ever. We are slow, careful, minimalistic about vaccines. They wanted to give her a bunch more. We came in for a TDaP and a sign off on the other optional ones. I had always never allowed more than three at one time (like only MMR, OR polio, not both...). That time they convinced her to do the flu. Unbeknownst to us, it was a four way. Plus, rather than give her the TDaP, they gave her an MMR that she didn't need. She was sick within minutes while still in the exam room. They said she was fine. By the time we got to the car, her back hurt so bad she had to lay down. Within a half hour she started to pas out upon standing. I called the office and they said she had the flu. On Tamiflu within an hour. Lost 14 lbs in two weeks. Uncontrollable fever, pain, fainting, utter weakness.... Second round of Tamiflu as soon as the first was finished. All by phone only. The staff refused to see it as anything unusual. I didn't realize what really was happening because I had never heard of cytokine storms. No vaccines since then. We moved from Washington state to Florida. We had to get a waiver for school. The staff person at the health department there said it is best to NOT get a flu shot with other shots, and also found the MMR/TDaP mistake.
@@ericjohnson624 dont get anymore if any kind. They all seem to have secret issues
@@ericjohnson624 one of the worst vaccines there are. Watch sacrifìcal virgins. All vaccines are dangerous
@@ericjohnson624 listen to your gut....you will have to research deeply ANY shot. They think they can put anything together now and call it a jabx. I won't take any... they already put flu jab with mrna now too. It is crazy