Khan academy never fails to amaze me. Thank you for presenting this topic in a way that is simple and easy to understand, and with awesome graphics that really help drive the point home! I don't think I could make it through nursing school without these amazing videos!
correction : with increase preload there is left ventricular hypertrophy due to volume overload and that's eccentric hypertrophy so heart chambers will get enlarged . and due to increase afterload the hypertrophy is concentric and with that heart chambers get smaller . overall a very good video for learning
So why do we treat heart failure with ace inhibitors which remove fluid from the body? According to this video, fluid is needed to increase preload and increase heart contractility.
Let me try to answer this question to the best of my knowledge. I can see why you asked this and I understand your thought process. ACE (angiotensin converting enzyme) inhibitors are primarily used to treat hypertension and heart failure. They don't necessarily have much of a diuretic effect, in fact they are k-sparing. About the fluid..our body already has anti-diuretic hormones, as mentioned in the video, that help with fluid fill up in the ventricles. That hormone (ADH) prevents fluid from leaving the body, so we don't necessarily need more fluid to have increased pre-load. We already have it by preventing diuretic effect. We do give diuretics to HF patients though, such as loop and thiazide diuretics. They come in to play mostly with decompensated heart failure to "suck" out the fluid build up throughout the body.
pumping more blood with hypertrophy produces more extra oxygen than it uses seems pretty obvious so that does not explain decompensation. It's also obviously the underlying cause that keeps making things worse and the cardiologists only knowing about the heart but nothing else in the body.
Hlo i have diagnosed hypertension concentric lvh and preserved lv function is it heart failure am only 22 year old please help me any one know what is it
Preload is the volume of ventricles in resting state, right before they contract. In this stage ventricles are "loading" up/ filling up with blood before they can pump it. AND yes you are correct in that afterload is more of a pressure. Afterload is correlated with contraction, the shooting if you will, of blood from ventricles.
The renin system allows Na and Water retention because the body believes that it needs to hold on to more fluid because it is not getting enough blood/fluid/o2. It is trying to compensate. RAAS releases ADH, which helps increase the fluid volume that is then needed to increase the pre-load.
It's really not elasticity so much as optimization actin-myosin cross-bridge alignment that increases force of contraction in stretched heart muscle, producing the Frank-Starling effect.
Thanks I am an 11 year old kid and I really want to be a cardiologist. It is much better than waiting until college and medical school :) .
go for it...
I'm Impressed keep it up and keep on learning brother 🤍
Currently in med school! See you in the hospital in 10 years!
Khan academy never fails to amaze me. Thank you for presenting this topic in a way that is simple and easy to understand, and with awesome graphics that really help drive the point home! I don't think I could make it through nursing school without these amazing videos!
I love the " help me move" analogy. I'm sending this to my son.
HIS VOICE IS OSMOSIS VOICE!!! lol. thank yoooouuu very much khan academyyy!!
omggggg
Yesss I noticed 😂😂😂
Right
:O
That friendship analogy about moving was spot on, I really pictured the receptors in that sense. Thanks mate✌️
Wow, this is a KHAN’S Video with OSMOSIS Flavor 👍😊
I think it's the same guy
@@kokocipher Yes, he is.
PERFECT EXPLAINATION. ITS JUST MADE MY MIND SO CLEAR!
Thank you for presenting such an easy-to-understand video!
correction : with increase preload there is left ventricular hypertrophy due to volume overload and that's eccentric hypertrophy so heart chambers will get enlarged . and due to increase afterload the hypertrophy is concentric and with that heart chambers get smaller . overall a very good video for learning
Perfect video and great explanation!!! Really appreciate Khan Academy's videos. Life savers 🥰
Amazing explanation! Thank you!
Great video! Very good. Thanks.
Omg thank you for making this video!!!
The analogy was great!
Amazing explanation, voice and analogy, only 1 thing: plz do it on a white background with bigger letters, and you will be the best on the whole tube
Wish my nursing instructors taught this well.
explained very well. its like crystal clear explanation. thanks
I know his voice anywhere!!!! #Osmosis 💜
Great explanation and illustrations. Thank you.
thank you so much! you explained it too clearly!
Wonderful as usual
This was an awesome explanation, thank you.
thank you thank you tnank you very very much 🤩🤩❤️❤️❤️❤️❤️❤️❤️❤️❤️
great explanation. Thanks Khan acadamy
Thank you
MY OSMOSIS MAN! ♥️
just one word perfect
Really amazing explanation
Great video! (Frank and Starling were 2 different guys)
Thank you! And great job teaching!
So why do we treat heart failure with ace inhibitors which remove fluid from the body? According to this video, fluid is needed to increase preload and increase heart contractility.
Let me try to answer this question to the best of my knowledge. I can see why you asked this and I understand your thought process. ACE (angiotensin converting enzyme) inhibitors are primarily used to treat hypertension and heart failure. They don't necessarily have much of a diuretic effect, in fact they are k-sparing. About the fluid..our body already has anti-diuretic hormones, as mentioned in the video, that help with fluid fill up in the ventricles. That hormone (ADH) prevents fluid from leaving the body, so we don't necessarily need more fluid to have increased pre-load. We already have it by preventing diuretic effect.
We do give diuretics to HF patients though, such as loop and thiazide diuretics. They come in to play mostly with decompensated heart failure to "suck" out the fluid build up throughout the body.
thank you!
thank you so much! 5/12/2022
Well explained superb
you sir are a legeeeennd
Good explanation but the Frank-Starling law is named after two people: Otto Frank and Ernest Starling.
osmosis guy on khan??? great combo
Wonderful just wonderful.
Excellent!
The ICU handbook
What a cute bear!
Amazing!!!
thank you a lot👍
Why then is it beneficial to exercise? Since that would increase compensation and decompensation?
Great
Thanx very match
U helped me alot
incredible thanks man :)
Good information
thankyou so much , now i get it
Muchas Gracias!
pumping more blood with hypertrophy produces more extra oxygen than it uses seems pretty obvious so that does not explain decompensation. It's also obviously the underlying cause that keeps making things worse and the cardiologists only knowing about the heart but nothing else in the body.
YA'LL THANK YOU :(( I'LL GET THROUGH MY CARDIO MODULE BCOS OF YA'LL
This guy 'Frank Starling'.
Its Frank and Starling isn't it?
i think you also can use shepherd and wolf as an analogy
better than osmosis
Osmosis
What about after load??
Good content but pinching fast voice
I miss the old Osmosis
Hlo i have diagnosed hypertension concentric lvh and preserved lv function is it heart failure am only 22 year old please help me any one know what is it
the osmosis guy's voice shocked me
Is this the guy from osmosis?
Yes
Isn’t preload the volume after filling, I thought afterload is pressure?
Preload is the volume of ventricles in resting state, right before they contract. In this stage ventricles are "loading" up/ filling up with blood before they can pump it. AND yes you are correct in that afterload is more of a pressure. Afterload is correlated with contraction, the shooting if you will, of blood from ventricles.
idk why but i feel sorry for that cardiac cell 6:11 😫😫
So osmosis like
How would the RAAS system work as a compensatory system in HF?
The renin system allows Na and Water retention because the body believes that it needs to hold on to more fluid because it is not getting enough blood/fluid/o2. It is trying to compensate. RAAS releases ADH, which helps increase the fluid volume that is then needed to increase the pre-load.
Slow down lil bit
👍👍👍
It's really not elasticity so much as optimization actin-myosin cross-bridge alignment that increases force of contraction in stretched heart muscle, producing the Frank-Starling effect.
Haaaay osmosis guy!!!
This is the guy from osmosis 😂❤️
I got social anxiety from an analogy XD
2:32 No.
👌👍🏻
You talk wayyyyyyy tooo fast...slow down and let people understand what you are saying, its hard to keep up when your going at 10000mph.