Eczema/Atopic, Contact Dermatitis, etc: Spongiotic Dermatitis Pattern - Inflammatory Dermpath Basics
HTML-код
- Опубликовано: 17 сен 2024
- Excerpt from my Inflammatory Dermpath 101 video (full video here: kikoxp.com/pos...) - A Beginner's Guide to Diagnosing Rashes for Non-Dermatopathologists. A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/pos... (dermpath) & kikoxp.com/pos... (bone/soft tissue sarcoma pathology).
Please check out my Soft Tissue Pathology & Dermatopathology survival guide textbooks: bit.ly/2Te2haB
This video is geared towards medical students, pathology or dermatology residents, or practicing pathologists or dermatologists. Of course, this video is for educational purposes only and is not formal medical advice or consultation.
Presented by Jerad M. Gardner, MD. Please subscribe to my channel to be notified of new pathology teaching videos.
Follow me on:
Snapchat: JMGardnerMD
Twitter: @JMGardnerMD
Instagram: @JMGardnerMD
Kiko: kikoxp.com/pro...
Facebook: / jmgardnermd
Excerpt from my Inflammatory Dermpath 101 video (full video here: kikoxp.com/posts/5244) - A Beginner's Guide to Diagnosing Rashes for Non-Dermatopathologists. A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).
I experienced this condition for the very first time on my right hand and fingers! It was unbelievably uncomfortable and it happened the end of December and gotten worse with blisters and inflammation over a month… thank goodness the doctor in the hospital did the biopsy procedure to find more details and boom! Spongiotic dermatitis! I had to take multiple anti creams and pills before the results were final. I gotta say, this was the scariest condition I’ve received in my life!
Hey I actually have the same diagnosis. I was wondering what your treatment plan was to get rid of it for final results? Thank you!
*Summary*
* *(**0:10**) Spongiotic Dermatitis Pattern:* This is a common pattern in skin biopsies characterized by fluid (edema) between skin cells (keratinocytes) in the epidermis. Imagine a sponge soaking up water, hence the name.
* *(**1:42**) Key Features:* Look for these clues under the microscope:
* *(**1:42**) Spongiosis:* The spaces between the keratinocytes are widened.
* *(**1:42**) Desmosome Spines:* Visible connections between the cells that look like spines, more pronounced due to the spongiosis.
* *(**1:42**) Scattered Lymphocytes:* A type of white blood cell found amongst the keratinocytes.
* *(**1:42**) Serum and Perikeratosis:* Fluid and retained cell nuclei on the skin's surface, often leading to a scaly or crusty appearance.
* *(**2:20**) Common Causes:* Several conditions can lead to this pattern, including:
* *(**2:20**) Atopic Dermatitis (Eczema)*
* *(**2:20**) Contact Dermatitis*
* *(**2:20**) Numbular Dermatitis*
* *(**2:50**) Eosinophils:* The presence of these white blood cells *can* suggest Contact Dermatitis, but they can also be present in other conditions, so their presence alone isn't definitive.
* *(**3:41**) Langerhans Cell Collections:* These collections of specific skin cells can be seen and are a normal part of this pattern. Don't confuse them with signs of skin cancer.
* *(**4:47**) Subcorneal Pustules:* If pus-filled bumps (pustules) are present, it's important to report them, as they can point to specific, rarer conditions.
* *(**5:11**) Important Note:* If you see this pattern and neutrophils (another type of white blood cell) in the outer layer of skin, always check for fungal infection! This can look very similar and requires different treatment.
* *(**6:54**) Clinical Context is Key:* While the microscope can show the spongiotic pattern, it's difficult to tell the exact cause just by looking at the biopsy. The patient's symptoms and the dermatologist's examination are crucial for making a diagnosis.
In short, spongiotic dermatitis is a pattern seen under a microscope characterized by fluid-filled spaces in the skin. It can be caused by a number of things and requires additional information to pinpoint the specific cause.
Summarized by AI model: gemini-1.5-pro-exp-0801
Cost (if I didn't use the free tier): $0.0410
Input tokens: 8638
Output tokens: 1024
Very nice explanation
I currently have this condition. Very itchy spots developing in my arms back and legs. Usually gets worse at night I have bought creams recommended by doctors all useless.
I am now getting much relief from hydrogen peroxide I dab it on with cotton wool. This is working well for me
Apply toothpaste on the area to avoid itching at night. I do it before I go to bed, it works . Try it.
@@theduckrc211v4 cheers I'll give it a go
What do you use for internal
@@nonjabulomsebeni3396 nothing
Have you ever used an electron microscope? Do you think it would be useful for anything dermpath related?
I have never used an electron microscope. It requires special skills and many institutions no longer have one. In modern pathology, its main use is for kidney biopsies to evaluate for glomerular and other medical renal diseases. In dermpath it is occasionally needed for diagnosis and sub typing of epidermolysis bullosa (rare congenital blistering diseases). Aside from that EM is rarely used outside of the Research setting anymore. Regular old school Light microscopes coupled with good clinical info (and immunostains or molecular testing in some cases) is pretty much all we need to make the diagnosis!
How is it treated?
@@timothykeyes3753 I have just posted what working for me