Pancreatic Cancer Vaccines With Amazing Results in Phase I
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- Опубликовано: 17 окт 2024
- Pancreatic Cancer Vaccines With Amazing Results in Phase I
Pancreatic ductal adenocarcinoma is one of the most lethal cancers with a 5 year survival rate of less than 10%. mRNA designer/personalized vaccines are changing this situation. Let's review the results of phase I trials.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Tuesday, Jun. 4 2024 11:37 AM
Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches | Radiation Oncology | Full Text
ro-journal.bio...
NHS England Thousands of NHS patients to access trials of personalised cancer ‘vaccines’
www.england.nh...
Three-year Phase 1 Follow-Up Data for mRNA-based Individualized Immunotherapy Candidate Show Persistence of Immune Response and Delayed Tumor Recurrence in Some Patients with Resected Pancreatic Cancer | BioNTech
investors.bion...
Investigational mRNA Vaccine Induced Persistent Immune Response in Phase 1 Trial of Patients With Pancreatic Cancer | Memorial Sloan Kettering Cancer Center
www.mskcc.org/...
Trial Design
www.biontech.c...
Cancer vaccines are having a renaissance | MIT Technology Review
www.technology...
NHS England launches scheme to boost signups for personalised cancer vaccine trials | The BMJ
www.bmj.com/co....
I don't believe a word these drug companies tell us.
And our dear Dr. Been should remember about that.
Both you and Me
I understand ♥️🕊
These institutions are pushing true science forward
@@sarahlulu4947 money not science
I am going to remain natural and whole without any designer therapies
"I am going to remain natural and whole without any designer therapies"
Totally understandable when dealing with mRNA vaccines for Covid-19, but with your back against the wall with Pancreatic ductal adenocarcinoma it could become a somewhat different story.
Nature is what gave the cancer, so letting it run its course means death for most people. Immunotherapy is using our body’s natural fighting system. We prevent deadly childhood illness by teaching T cells what to fight. Why not teach them to fight cancer?
Thanks again.
So glad I'm still in the control group.
Thanks again Drbeen. Another amazing breakthrough in fighting the big C or let's hope. Been a big fan since your production on the little girl that lived through leukemia. Thanks to these amazing brains on the case, this is just the beginning.
You are welcome. I am excited for the progress being made in this area.
Ill never trust doctors or the science ever agian.
No thanks ill go when God wants me to with the dna he gave me ❤
Well, I wouldn’t throw the baby out with the bath water. Hopefully the medical system will move back toward decentralized or even private practices. Personally, I’ve started to use integrative healthcare (not covered by insurance). I pay 30% more but it’s my health!
@@meekoosh sorry no hope left for healthcare.ive been traumatized
This is such exciting news. My brother is currently waiting on his next to last treatment but they’re on hold due to low platelets. He had the whipple surgery after almost zero symptoms. He is a now a shell of the greatest oldest brother ever known. This is the future of true medicine. God bless❤️
Strong side effects is the heartbreaking reality of many patients receiving intense chemotherapy which cannot tell the difference between a dividing cancer cell and a dividing healthy cell. This is why so many people lose hair and face nausea. This is exactly what immunotherapies are hoping to prevent. By using the patience’s immune cells, it should provide an intelligent and specific target system that easily tells apart cancer from healthy tissue
It would be great if you could get him into this study! It's such a terrible cancer, and the chemo can be harsh. Praying for you both.
HELL TO THE NO
I feel anything that is involved in mRNA technology should be banned
I hope this works, as pancreatic cancer is a horrible way to go. Watched my mom go thru it, and she was gone 2 weeks from her diagnosis. Scares the hell out of me, because the signs are so subtle, it's usually too late to do anything
You are correct. This is why this intervention will be amazing if proven through all phases of the trial. Fingers crossed.
@DrBeenMedicalLectures the trials can be faked , look at the past history of the vaccine comanys .
It looks good on paper , but in practice is a disaster
@@gazza124561 Probably better off injecting the paper into ya
Any updates??
This is very important and hopefully the public will not shy away from vaccinations ♥️🙂⭐️
I lost three friends to this cancer just this year. This therapy is very hopeful. Thank you for your thorough discussion.
Cancer and diseases such as auto immune diseases and blood clots have risen dramaticaly ,my son inlaws father died of cancer yesterday .
seems after the third booster the imune system becomes compremised.
My brother in law is fighting mestatic prostrate cancer and my wife is making a trip to Queensland to say goodbye to two of her aunts also dying of cancer.
The regulatory bodies universities politicians and media receive enough funding from huge pharma profits to be dangerously influenced.
Also many with share portfolios (like my brother ) are understandably reluctant to think badly of pharma.
Now the evidence of the extent of harm done is emerging ,slowly ,but sofar the situation is too embarrassing for many of those involved to admit to
All vaxxed?
All vaxed
Sorry for your loss. Were they vaccinated?
This is certainly interesting but realize mRNA genetic therapy is not the only way to teach the immune system to target the cancer. There are likely much safer ways. But since the mRNA platform have such a high profit margin, that is likely all we will get.
Institutions around the country are working tirelessly to fight this disease with immunotherapy. For example Tumor Infiltrating T cells are already being harvested directly from the tumor tissue. These know how to fight cancer already but are exhausted from the fight. These can be grown outside of a person and then given back stronger and healthier. See the work of Dr. Shari Pilon-Thomas in Google Scholar for details
The sad truth is all of the vaccines should be made for us individually. I am done with them myself until I see proof in results.
The main reason for the recurrence of any cancer leading to metastasis is the treatment itself. The treatment don't treat the cause but the symptoms.
At least this is what the MRNA was actually designed for, I hope all is good in a few more years with these patients.
Thank you Drbeen ♥️🙂
But can they create a vaccine for the vaccine?
Maybe you mean adjuvants. These trigger stronger initial responses “boosting” the vaccine so the initial immune response is more effective
SuperVac?
Any validity to Angus dalgleish’s vaccine (melanoma and pancreatic cancer)?
I will check.
@@DrBeenMedicalLectures Thank you Dr Been
Welcome
🧠⚰️💉☠️
I hope this has some truth to it. It is difficult to believe anything these medical companies say…
Phase I looks fine. Fingers crossed for the next phases.
Interesting from someone that got his direct family injured from MRNA, that's a big disregard from previous harm of these technology...overconfidence can kill...
Any update on Ph II?@@DrBeenMedicalLectures
Ask the 6 people who are still alive from the vaccine
Dr Been tell people here about the article in the British newspaper The Telegraph.
Any uodate on Phase2 trials?
sounds like good news. my concern now, is, how much will they be charging for this miracle life extending treatment! your life or your life savings...
Dad passed from PC in 2003 5 weeks after diagnosis - declined treatment as it was stage 4. He wasn't feeling well for 6 months before that and was told it was indigestion and to take Tums. PC is hard to detect and shouldn't be the first thing you suspect - don't blame them.
Sorry to hear that.
They should make a ‘vaccine’ against Stockholm syndrome 😅
Is it safe and effective? 🤔🤐
Dr Been, if you haven’t discussed the BCG vaccine, would you be able to discuss this please?
I understand everyone’s reticence about new therapies from these disreputable companies, but if you’ve got pancreatic cancer it’s probably worth taking such a risk.
Here’s to hoping something helpful comes from this type of research, even if that means the very same people who previously harmed others achieve financial success.
This is very encouraging news. I'll bet the individualized vaccine will cost a pretty penny, though.
I think so too. It might become a therapy for rich only.
Yeah... penny and one of your kidney for sale
How long would it take for this technology to come to market and be approved for use by health insurance companies? Interesting, but seems impractical for time-sensitive aggressive cancers like pancreatic cancer at this time. Would this mNRA vaccine techology theoretically work for ovarian cancer?
Thanks, Dr. Been!
I think the suggestion is that, yes, this can be used for other cancers too. You need to be in the right place at the right time though, so staying healthy is the goal!
Given the problems with the Covid mrna vaccine, will we have the same problems with other mrna vaccines?
The difference is that these new treatments are given to people with cancer, not to healthy people.
I thought your title meant the one that caused pancreatic cancer a few years ago. I knew 5 younger people (under 60)with pancreatic cancer all at once in my area, several of them passed away. When I had only known one in my lifetime. So now they will unleash their cure? I’m sure they do.
😢this talk gives me the creeps, pstd so I will now turn it off.
No more experiments untill the who and cdc are disbanded and governments refuse to give indemnity and hold a nuremurg trial to bring justice
This is interesting. However, I have heard that cancer immune therapies sometimes result in enhanced disease ("hyper-progressive" is the official term) in a subset of recipients.
We will find out more in phase II.
Drug companies do the research that is relied on by the FDA to approve the drugs. If a drug has 20 % of a certain side effect and they report 10% who can find out?
Unfortunately, doctors and anything from pharmaceutical companies has lost all credibility and trust
I have to wonder about cancer stem cells - whether these targeted vaccines will address these. So often the achilles heel is when cancer recurs because the stem cells are not killed by treatment.
That's an interesting question. I don't have data for this yet. Will research.
@@DrBeenMedicalLectures Dr Marik mentioned this about stem cells. It might be in his cancer monograph.
I know about the issue. What I don't know is if this therapy will help to fix them or not.
"Amazing results"?
Any independent and fully transparent verification?
Don't ask silly questions 😁
@@BeaHindebars 🫨
Magic Health Juice
Yeah... No
I respect you cover studies on vac good or bad. It shows objectivity. I am confused how a disease researchers are still working to fully understand can have a shot (albeit in study phase) showing potential to prevent it. If they now understand it that well why not work on effective treatments and non drug prevention?
We can still make an effective therapy without understanding everything about pancreatic cancer. We understand how the body recognizes cancer using immune cells. Neoantigens are special proteins that only the cancer has on the cell surface. We teach the cells of our immune system to recognize neoantigens using the vaccine. It’s like when someone posts a “most wanted poster” in the center of a city. You don’t need to know the life story of the criminal in question, just how to recognize him and alert authorities. Similarly, a vaccine can teach the body how to recognize and attack pancreatic cancer even though we are still unraveling the biology behind this disease.
Who are you?
How can you trust any study?
You telling me you believe the data? Not me
They can't just make up this small phase 1 result data.
@@DrBeenMedicalLectures They can, remember the phrase , SAFE AND EFFECTIVE, it stops transmission, etcthey can make up ANYTHING. You see they changed the definition of a vaccine. A true vaccine offers immunity, you're telling me this offers immunity to a cancer, not a chance. Anything with mRNA will not be entering my body.
@@DrBeenMedicalLecturesthey did it with covid jabs.
@@teachingwithipad Exactly. Why are we still falling for this.
@@DrBeenMedicalLectures Now you get to see just how much damage the medical profession has done to their reputation. Frankly, after the last 4 years, the statement you just made is laughable. Really, I laughed at the screen reading that, it's funny, no joke. :) These people would tell you cyanide is good to go if you gave them enough money.
So the trial results are only relevant to patients after resection and other SOC treatments? Many PDAC patients aren't lucky enough to be operable. At diagnosis my husband didn't even have mets, and still wasn't operable. Than he had chemo combined with Valter Longo's protocol, the tumor shrunk, but still was too close to blood vessels. Now my friend have been diagnosed with same cancer. Only one blood vessel is involved and she's not operable, since the tumor is again too close to large blood vessels.
So sad to hear this. This study was not surgery, meaning operable, it was just a biopsy, usually done with a large needle inserted using ultrasound. My guess is that you have to live in the UK to be part of this study. Hopefully the next trials will be successful and it will be available in other countries (likely in large centers that can do genetic testing).
@@Hiris-hu5pc I know the study wasn't surgery. What I meant was patients eligible for the study were post resection, which does not happen often in PDAC. Typically these tumours aren't resectable , So it's not a huge breakthrough. Plus, it's Pfizer, so...
@@KatieZeldin Yes, as is common with new treatments, the patient must have had other treatments first. Frustrating to say the least. Especially when the prognosis is so poor.
Haven't we learned our lesson with shots???
There's no lessons that make spines and gonads grow.
@@solaroid4442 Agree....or Brains
I have a degree in molecular biology and am a retired pharmacist. I will never take any vaccine again until we have a change in the current regime! I’m thinking the mRNA is all of the recent vaccines! How do we know?
mRNA is one of the most quickly degrading compounds in nature. It’s transient by nature. If you compare it to some of the earlier attempts to vaccinate people with literal cocktails of live virions, this is much much safer
What about other meditation, can it be made of/with mRNA?
Yeah….
I wonder, could later on, neo antigens be harvested or created to maintain maybe a better verison of auto immune suppression for patients?
A new screen done later on would add cost but would update the pool of neoantigens as well! It could be more effective at preventing antigen escape or loss of response to this particular pool of immunotherapeutic peptides
I have question does bronchiectasis damaged both of lungs ?
It is the process of lung injury from infection that can happen to any part of the lung. It may damage both lungs, or it may just damage one lung, or if you are lucky just part of a lung. The only way to know for sure would be to test and confirm with a doctor (most clearly visible by chest X-ray)
@@sarahlulu4947 I was tell both lungs but i what know their turth
We know the side effects data etc the real question is the ones that took it is it like a ticking time bomb ?
The real ticking time bomb is pancreatic cancer. This freezes the clock. So the real real question is how long can we keep the clock frozen?
Are you aware that the level of IGG4 is high in vaccinated, which might fuel the cancer in the first place?
Until the causes are found disease free will never exist! Wouldn't it be easier to start searching the causes for all these problems!🧐
They don't make money from preventing diseases
Wheeee! Imagine a life without pancreatic cancer!😎
Nope
Wow... congratulations scientific community...
It's a big deal.
I hope its not brought to you by pfizer
This is BionTech and Genentech. Although, for COVID BionTech was the technology producers and the Pfizer was the delivery and sales platform.
BionTech Is also a criminal company, please doctor watch the David Martin World videos on the info about it
@@DrBeenMedicalLectures They made billions! Enough to pay any endorser.
I can't wait for the side effects to be truly known.
Not for me, thank u. Safer ways available.
For pancreatic cancer??? Doubtful.
Who would believe that now? They can say anything and get away with it.
Right......
It’s actually very very hard to publish anything in top science journals like Nature. We are talking years and years of back and forth critique from independent investigators reviewing the data. Yes scientists are human and can get things wrong. But on the whole it’s our best chance at making a difference for real people. It keeps us up at night, devoting our creative energies to this mission. Hopeful that one day we will discover a cure to this terrible disease
@@sarahlulu4947the articles in Journal should keep people up at night but not for the reason you're suggesting.
Dr Been have you seen the article in the British newspaper the Telegraph? It was to do with a paper by Dutch scientists. Perhaps you should do a video on it.
Revelation 13:14
And deceiveth them that dwell on the earth by the means of those miracles which he had power to do in the sight of the beast;
Don’t be ridiculous
interestingly, pancreatic cancer seems to be a side effect of the you know what