LADA (Latent Autoimmune Diabetes in Adults)

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  • Опубликовано: 24 июл 2024
  • LADA (Latent Autoimmune Diabetes in Adults) is the most missed diagnosis in diabetes. It’s often initially diagnosed as type 2 because the loss of pancreatic beta cells is much slower than the more “traditional” form of type 1. We’ll explain the typical stages of the condition and share which tests can determine a type 1 diagnosis. (Schafer Boeder, MD) - TCOYD Virtual Diabetes Conference and Health Fair 2020

Комментарии • 58

  • @howardkamerman690
    @howardkamerman690 3 месяца назад +2

    My pancrease nearly quit in 2001 I nearly died. 2022 I was diagnosed with type 1 diabetes and diverticulitis and congestive heart disease. It’s been a rolercoaster. I’ve got a pacemaker. It’s very hard to regulate my. Glucose I’ve had to give up the good stuff I’m 71 yrs I’ve had a good life but I’m not giving up my wife and daughter help me a lot. 😊the latest grand daughter is such an angel she takes to me a lot!! I’ve got 2 girls and 2 sons I’m proud of them all. We have a nurse and a doctor in our family god has been real good to us. Your story helped me a lot! Thank you.

    • @TCOYDtv
      @TCOYDtv  3 месяца назад +1

      Any medical illness can make blood sugars harder to control, and certain medications like steroids can also wreak havoc on blood sugars. Sorry for all you are going through but hang in there - sounds like you have a great support system!

  • @gabbaba1234
    @gabbaba1234 9 месяцев назад +7

    Good stuff! I was actually diagnosed correctly from the start by a doctor in the ER who recognized the differences in symptoms mentioned. I had DKA presenting around 500s at 29. I can't imagine the frustration others may have felt. The education posted in videos like this really assist doctors in questioning their own biases. I asked the ER doc how she arrived at this conclusion so quickly. She mentioned she had CE three months prior on LADA. It really shows how badly this info needs to be distributed.

    • @TCOYDtv
      @TCOYDtv  8 месяцев назад +1

      Agree - thanks for sharing your experience!

  • @jameslea312
    @jameslea312 7 месяцев назад +4

    When I was diagnosed in ‘21 at 25 years old they tested for GAD and my C peptide. While on the lower side, my C peptide was still technically in a normal range. But there was a presence of GAD which sealed my fate.
    It was probably 6 months of Lantas and then full MDI after that. Decently fast progression.
    Thanks for the informative video, as much as I hate being diabetic I do really enjoy learning more and more about it.

    • @TCOYDtv
      @TCOYDtv  7 месяцев назад +1

      We're both sorry and glad you're part of the TCOYD family...but it is a pretty fun group! Thanks for watching, and let us know if there is anything in particular you have questions on anytime!

  • @YounessOu
    @YounessOu 8 месяцев назад +2

    it's crazy that I was diagnosed with this exactly at the time you uploaded this video

  • @debbiesearle8442
    @debbiesearle8442 2 месяца назад +2

    Thanks so much this is the best explanation by far I have come across for LADA. I was miss diagnosed as type 2 for 5 years before experiencing DKA and ending up in ICU where I was diagnosed with LADA. It sure has been a steep learning curve since diagnosis nearly 4 years ago but so grateful for access to information like on TCOYD even on the other side of the world. In Australia. Keep up the great work team. Debbie

    • @TCOYDtv
      @TCOYDtv  2 месяца назад +1

      Thanks so much, Debbie. It is tough for sure to not have the right diagnosis from the get go. Glad we have been able to help.

  • @genm303
    @genm303 10 месяцев назад +4

    Thank you! Great information, best I've come across and very helpful to me...diagnosed with LADA age 71 so came as a bit of a shock but coping with it.

    • @TCOYDtv
      @TCOYDtv  9 месяцев назад +2

      Oh goodness! If you have questions about anything please let us know...there's definitely a lot to learn. :)

  • @sharonolang-yj4gk
    @sharonolang-yj4gk Месяц назад +1

    This lecture is phenomenal. Thank you.

    • @TCOYDtv
      @TCOYDtv  Месяц назад

      Appreciate it - it's an important topic for sure. Too many misdiagnoses.

  • @biagio230
    @biagio230 3 месяца назад +1

    I am a 49 year old male. Was misdiagnosed one year ago on T2D (but just slightly overweight with BMI still below 30) and finally yesterday got the diagnosed with Lada, after blood panel test on all antibodies(3 values to high).

    • @TCOYDtv
      @TCOYDtv  3 месяца назад +1

      Glad you were finally able to get the right testing and the right diagnosis.

  • @kayla764
    @kayla764 8 дней назад

    This was so helpful, thank you!!

    • @TCOYDtv
      @TCOYDtv  8 дней назад +1

      You're welcome - so glad it helped!

  • @ih7942
    @ih7942 3 месяца назад +1

    Great info. I wish I could carry this around and play for people so they understand that despite the age of onset, it is not a reversible lifestyle induced condition. Thankfully my endocrinologist is excellent and I was diagnosed correctly (sky hi gada, and lada is my 3rd autoimmune dx). But it did take some prodding on my part to get diagnosed. After a few years of strict carb reduction and monitoring Im now on a pump and cgm. Thankful for this technology but having to think about it 24/7 is a bummer. Also gaining 15 lbs once insulin started is another bummer (bmi is still normal). Also, my a1c does not 'track' properly in the words of my doc. Makes it all more difficult. Wonder if anyone else has this issue?

  • @jennifertucker6005
    @jennifertucker6005 2 месяца назад +2

    Going through blood work right now for all this 😩 doc mentioned perhaps its diabetes. I'm losing so much weight, today I'm 127 and just end of February was 145. A year ago and a half from today i was 200 lbs. I just keep going down and not trying to. I did start watching what i ate my i feel once i hit 150 there was no reason to lose more. I eat, i do. Last two days ive intentionally ate so much more and I'm stil at 127. I have lupus, so i figured this was all lupus related. But now I'm itching, slow to heal, the brain fog is so much worse, so fatigued for the last 4 months, when the 6 months prior i thought i was feeling "better". Oh and the last 4 months, blurry or hazy vision, like feels i have watery eyes but they arent watery, longer to focus ugh. Oh and been on my period for 10 weeks. I never thought this could be diabetes related, just lupus or something. I was really shocked to hear possible diabetes from the doc. I should get a call soon this week with results. Its driving me a bit crazy now 😭

    • @TCOYDtv
      @TCOYDtv  2 месяца назад +3

      That's a lot to deal with for sure...if you are concerned that it could be type 1 diabetes, ask your doctor for the GAD autoantibody testing.

    • @jennifertucker6005
      @jennifertucker6005 2 месяца назад

      @TCOYDtv thank you, I certainly will!

  • @darcysbestlife
    @darcysbestlife 2 месяца назад +2

    This is so helpful! I put my symptoms into ChatGPT and it spit out LADA. my primary doctor wasn’t familiar with it

    • @TCOYDtv
      @TCOYDtv  2 месяца назад +1

      Creative way to use Chat GPT. Show your doctor this video!

    • @yennyjen5742
      @yennyjen5742 22 дня назад

      What ChatGPT? I tried to look it up but had a couple websites showing differently sites. I don’t fit for type 2, metformin it’s not working, I was tested for lada and type 1 but came negative 😢

  • @TopgunB
    @TopgunB 8 месяцев назад +2

    No mention of measuring C peptide and fasting Insulin diagnostic for Type I and very helpful in LADA or did I just miss it? I know most ordinary doctors hardly ever look at them and don't often know how to interpret them but I know that's not the case for endocrinologists?

    • @TCOYDtv
      @TCOYDtv  8 месяцев назад +6

      Insulin levels and C-peptide are not helpful in LADA because people with LADA can still secrete some insulin, so the GAD is the most specific way to diagnose LADA. C-peptide can be very misleading.

  • @peeezn
    @peeezn 3 месяца назад +3

    Hi thanks for the helpful video,
    would you please find time please to answers couple of my questions.
    I appreciate it very much.
    I am 44, 193, 93kg, was diagnosed with LADA two months ago, where my zinc transporter was the only antibody that was high. (127RE/ml). And I got into hospital with 730 sugar. I assume I am now in that honeymoon phase. I take only basal (4-5IE) once in the morning, my CGM average now 6,2 and 123, so it is all ok for now, waiting for the future to come. But anyways.
    Can you assume how long it can that remission take/remain with only zinc being high ? Or how slow or fast are the Beta cells destroyed with only zinc transporter antibodies present ?
    I find online only how long it may last if you have GAD positive, or IAA (months or years), nothing about zinc transporter ? Is there any study on how fast it gets destroyed with those zinc Transporter antibodies? Or there is no ways to predict something like this? Or what test would help to get the info?
    And than, if I may, i am now 2 months into Lada and i still have symptoms, like tingling in hands and feet, dry itchy skin, blurred vision. Are those symptoms for ever, or can I somehow get rid of them, or can I do something against them and if yes, what? everybody is mentioning these symptoms but that’s all, nothing about how to treat them.
    Thank you very very much

    • @TCOYDtv
      @TCOYDtv  3 месяца назад +2

      There might be data on that one singe autoantibody, however I’m not aware of any. There’s no way to predict how long the honeymoon phase will be, but the best thing to do is to keep your blood sugars in good control, as they are now. Regarding your symptoms, blurred vision is typically due to rapidly changing blood sugars, and it should only last several weeks...not too much longer than that. Tingling in hands and feet and itchy skin doesn’t really make sense in someone with early type 1 diabetes. It would be important to see your primary care doctor or endocrinologist and ask about those symptoms.

  • @yennyjen5742
    @yennyjen5742 22 дня назад

    I am 34 yrs old, got gestational diabetes at 29 and have been prediabetic ever since. I am normal, actually on the lower side of weight since I lost 10 pounds while on metformin.. I was tested for type 1 and ñada and came negative 😢 my a1c it’s 6.1 and fasting insulin 8. Before starting metformin a1c was 5.9 and insulin 6.9 😢 I been tested for a couple genes for mody and came negative too

    • @TCOYDtv
      @TCOYDtv  21 день назад

      Please see our other posted response -

  • @Rhanyra
    @Rhanyra 10 месяцев назад +2

    hi! I was diagnosed type 2 when I was 25. But after a few years I was put on insulin because the pills werent keeping me controlled. I lost 60 pounds! Then I started going into DKA every year. Now I am 37, My doctor says I *probably* have lada, and now i have afib, high blood pressure and have to see a kidney specialist.

    • @TCOYDtv
      @TCOYDtv  10 месяцев назад +4

      That is often the case for people with type 1. Has your doctor run the proper tests to confirm his type 1 suspicion?

    • @Rhanyra
      @Rhanyra 10 месяцев назад

      @@TCOYDtv he referred me to an endo who put the orders in for the testing. I just havent done it yet. But I will be doing all my blood labs this week. Just got out of the hospital and don't have any good veins left so have to wait for them to heal.

    • @Rhanyra
      @Rhanyra 10 месяцев назад +1

      @@TCOYDtv the crazy part though is I remember having symptoms of hypoglycemia when I was a teenager. But my family was poor and we didnt go to the doctor so theres no way I could have been diagnosed with type 1 as a child.

  • @jstavene
    @jstavene 7 месяцев назад +1

    Can a person be lada and not show antibodies? I was immunotherapy for a year(keytruda) then my thyroid went in my last 3 infusions,,,then a few months after my pancreas,,,deemed type 2,,, on orals,,,then a couple months later type 1.5,,, saw different doctors and next said type 2 because of antibody tests,,,but on insulin, 4 times a day basil and bolus,,, and trying ozimpic in the event type 2,,waiting to see a endocrinologist ,,, but 1 doc says type 2 one says type 1.5 and diabetic educator says I have parts of 1 and 2,,, (also I got white hair blotches I think from the keytruda ) ,,,

    • @TCOYDtv
      @TCOYDtv  7 месяцев назад +2

      It’s possible to have antibody negative type 1 diabetes. Believe it or not, there are certain types of therapies that can cause a type 1-ish diabetes. It sounds like you have what looks like type 1 but without the antibodies, so I would put you as antibody negative type 1 that could be due to the immunotherapy. Confirm with your endo if the immunotherapy you were on could have cause you to have a type 1-like picture.

  • @SuperPromethee
    @SuperPromethee 8 месяцев назад +1

    my c-peptide is ...0.6 after lunch...am i...? im using only insulin injection...and im 50, diagnosed as diabetics 4 years ago...

    • @TCOYDtv
      @TCOYDtv  8 месяцев назад +1

      If you aren't sure if you have type 1 or type 2, talk to your doctor and have him or her run GAD tests which will determine a type 1 diagnosis.

  • @Vipin21o3
    @Vipin21o3 Месяц назад +1

    Hi, I am 34 and I was tested for DM last year with Hba1c of 6.9, I am as of today at 6.6 with following a regular diet plan and daily exercise, I did my fasting C-peptide today first time and it 0.52 ng/ml against a normal range of 0.8-3.8, I am lean, doc said he is sure I am type 2, waht do you think?, thanks.

    • @TCOYDtv
      @TCOYDtv  Месяц назад +1

      The first thing I suggest is to find a doctor who went to a good medical school. The second thing is, you are definitely not a type 2! You are most likely LADA with a slow beta cell destruction and thanks to your lifestyle efforts, you're doing excellent. My question to you is, did you get tested for insulin autoantibodies?

  • @erikawestphal5697
    @erikawestphal5697 Месяц назад +1

    Is it possible to get LADA at 23 years old and need insulin right away?

    • @TCOYDtv
      @TCOYDtv  Месяц назад +1

      Posting here too in case you don't see our other comment on the other video:
      Because you have positive antibodies, you have type 1 diabetes, and LADA means that you picked it up so early, you didn't have symptoms or your blood sugar wasn't totally through the roof. It doesn't sound like you ever went into ketoacidosis, and you were able to tolerate the high blood sugars, so I think you may have had LADA that was just poorly treated, and because you had LADA you didn't go into ketoacidosis like most type 1s. The bottom line is that you have type 1 diabetes and it sounds like you're doing great on insulin. I hope you have a CGM and would consider a hybrid closed-loop system one of these days.

  • @yennyjen5742
    @yennyjen5742 22 дня назад

    If one was tested for type 1 and lada gad 65 antibodies and came negative.. is it possible to develop it overtime since I don’t fit in the perfil for type 2? I was tested for mody too. Negative.
    Metformin hasn’t move my numbers, actually my a1c went from 5.9 to 6.1 while on it

    • @TCOYDtv
      @TCOYDtv  21 день назад +1

      It sounds like we aren't sure exactly what type of diabetes you have, but you do have insulin secretion based on your numbers, and your A1c is extremely low. Do not worry. If your A1c starts to creep up further you can be tested for type 1 again, and there are multiple autoantibodies you can test. You can read more about that here:
      tcoyd.org/2023/10/i-screen-you-screenwhy-everyone-should-be-screened-for-t1d/

    • @yennyjen5742
      @yennyjen5742 21 день назад

      @@TCOYDtv is it? My dr told me anything above 6 was considered diabetes and since I come from a long family history of diabetes she told me it’s in my genes and urged me to start the max dose of metformin (2000mg) I can’t handle and been taking 1000 but it’s not doing anything for my numbers. I been stressing over a lot.
      Thank you for your reply.

    • @yennyjen5742
      @yennyjen5742 21 день назад

      @@TCOYDtv does my numbers sounds like insulin resistance? Metformin hasn’t been working

    • @TCOYDtv
      @TCOYDtv  17 дней назад

      If you do have insulin resistance and your numbers are good with or without metformin, then your body is compensating for the insulin resistance and once again I would say we don’t know exactly what’s going on, but please don’t worry. You’re following yourself so closely, you will not have any issues with your diabetes the way you are so closely following it. -Dr. E

  • @SailorSlay
    @SailorSlay 4 месяца назад +1

    I’m going to ask my doctor about LADA because I’ve been having similar symptoms for years now.
    Is it possible for LADA to be triggered by pregnancy. These symptoms really kicked off after I began having children at 25

    • @TCOYDtv
      @TCOYDtv  4 месяца назад +1

      Probably best to check with your provider in your situation.

  • @georgewilson1457
    @georgewilson1457 5 месяцев назад +1

    I had a GAD test the result was 5 does that mean I have lada

    • @TCOYDtv
      @TCOYDtv  5 месяцев назад +1

      Not necessarily, as you need more tests and a history and physical exam.

  • @mitalpandya8798
    @mitalpandya8798 10 месяцев назад

    Good information but no empathy and very negative way of putting out things, which can increase worries in patient with LADA

    • @TCOYDtv
      @TCOYDtv  10 месяцев назад +1

      Sorry you feel that way. Dr. Boeder is an excellent endocrinologist with a lot of compassion, and we go to great lengths to provide diabetes education in positive manner.

    • @roms515
      @roms515 5 месяцев назад

      Hello my is also diagnosed with T1D 15 days before

    • @roms515
      @roms515 5 месяцев назад

      My son is 3 yrs n diagnosed with T1D