Retrosynthetic Analysis

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  • Опубликовано: 26 июл 2024
  • These are the hardest problems! You have to think backwards in time? What am I, H. G. Wells?! Relax, friend. You just have to dismantle the target molecule in strategic ways that make sense because of the synthetic transformations you have in your bag of tricks. Give this a gander and you'll see.
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Комментарии • 58

  • @MrHappyface198
    @MrHappyface198 7 лет назад +191

    I appreciate the work you put into these videos, unfortunately i still suck at organic lol.

  • @PowerSuitNinja
    @PowerSuitNinja 8 лет назад +15

    Hey Professor Dave! Thanks so much for all your help with Orgo 1 and 2 this year! Your concept videos were awesome. Wouldn't have been able to get though it successfully without your help!

  • @abhishektiwari7643
    @abhishektiwari7643 3 года назад +2

    Whenever I need a little brush up of any concept ,your videos help me out
    Good job pro

  • @imbatmanlol
    @imbatmanlol Год назад +5

    Only part of organic chemistry that dare I call, “fun”

  • @BangMaster96
    @BangMaster96 4 года назад +4

    This is like a top down approach, you start from the finished product, and derive its components.

  • @abhisheknair5630
    @abhisheknair5630 7 лет назад +2

    Your videos help a lot..Thank you so much.

  • @ranjanpaudel698
    @ranjanpaudel698 6 лет назад +8

    thank u sir...really appreciated ur vid....its goin to help me in my xms...

  • @helmifauzi2669
    @helmifauzi2669 6 лет назад +3

    love it so much, so helpfull thank you from Indonesia

  • @gauthamkrishna
    @gauthamkrishna 7 лет назад +4

    this is really helpful,thanks as I did not understand this in wikipedia and quora thanks!!😁😁👍👍

  • @TheBalls55
    @TheBalls55 5 лет назад +27

    Professor Dave finds lots of " medicinal" compounds in nature.

  • @apurbamondal3725
    @apurbamondal3725 6 лет назад

    Thank you sir ...for helping me out

  • @user-md1uq8nz6i
    @user-md1uq8nz6i 7 лет назад +1

    thank you so much

  • @ivanbombana7282
    @ivanbombana7282 5 лет назад +3

    very beautiful….. do you have other videos like this? With much more complex molecules?

  • @tealwalters990
    @tealwalters990 5 лет назад

    Thank you!

  • @user-de4uw7lz9n
    @user-de4uw7lz9n 5 лет назад

    Thank you very much!

  • @shubhampal8754
    @shubhampal8754 6 лет назад

    You are a super hero!!!

  • @shyamlokhande3466
    @shyamlokhande3466 6 лет назад

    Its really helpful......

  • @mosuputsasuzanne3905
    @mosuputsasuzanne3905 2 года назад +1

    You're the best...understood

  • @tantech2769
    @tantech2769 4 года назад

    Thanks!

  • @xXRachelClaireXx
    @xXRachelClaireXx 5 лет назад +2

    Have you ever considered doing meet and greets in CA professor Dave? Love your videos!!

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  5 лет назад +4

      i would be up for it! but who is it that would want to meet me?

    • @Politickticktickin
      @Politickticktickin 5 лет назад

      @@ProfessorDaveExplains Haha she wants the D and you want Rachel's P LOL

  • @ananuraidaputri9298
    @ananuraidaputri9298 7 лет назад +2

    Thank you Sir for this information

  • @roxygaming437
    @roxygaming437 Год назад

    Thank you so much sr♥️♥️♥️

  • @youtubeedchannel1730
    @youtubeedchannel1730 Год назад +1

    Can you do an excercise to obtain a heterocycle compound? Thanks for your content

  • @Amy-se5ld
    @Amy-se5ld 7 лет назад +2

    Can you do retrosynthesis for aldol condensation reactions?

  • @tesfayeayisa1253
    @tesfayeayisa1253 2 года назад

    thanks

  • @ravindrnathsstories2505
    @ravindrnathsstories2505 6 лет назад +1

    Which book is best for retro synthesis please advise sir

  • @nivedithag8427
    @nivedithag8427 4 года назад

    sir ,could you please post a video on synthesis of peptides by sheehan's method

  • @ahmedkhlifi9266
    @ahmedkhlifi9266 5 лет назад

    I have a restrosynthetic synthesis exam can you help me with some links that could guide me please

  • @kevinsoun3030
    @kevinsoun3030 7 лет назад +1

    For the first reaction, should we use MgCl? When you radically halogenate the propyl group with Br, it is more selective for the secondary carbon and that would yield a different product. We should use Cl because there is only a negligible difference between the selection of a primary vs secondary carbon??

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 лет назад

      i'm not sure what you're asking, if it's for the grignard one, from the starting material we use PBr3 to go from alcohol to alkyl bromide, so there is no radical halogenation.

  • @misskaruna6854
    @misskaruna6854 5 лет назад

    Pls give me the name of refrance book for parcticing retrosynthetic analysis........

  • @jdubzz9812
    @jdubzz9812 Год назад

    could we just react the DB at 6:30 ish with 2 equivalents of O3 to create two ketone groups and turn those into alcohols with NaBH4 to create our alcohols?

  • @mattikore5796
    @mattikore5796 3 года назад

    Sir what is the synthetic equivalent of co groups tell me

  • @kevinsoun3030
    @kevinsoun3030 7 лет назад +1

    And also, why do we need to use PCC if the grignard reagent already kicks out the double bond with the O--thus making it OH??

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  7 лет назад +2

      again not sure i understand, PCC is needed to go from ethanol to ethanal. remember that the retrosynthetic arrows are not forward arrows, they go backwards, each arrow leads to the precursor of what you're looking at, so the alcohol came before the aldehyde, it's not that we are reducing an aldehyde to the alcohol.

  • @FatBellyChemist1234
    @FatBellyChemist1234 2 года назад

    If I had looked at this earlier I would have done Honours by now.

  • @Natalie-yv2go
    @Natalie-yv2go 6 лет назад

    Is there a good place to drill these practice problems? I've taken a look at your practice problem videos. I've also searched and found some practice sheets, but they aren't really enough for me. Is there a site or app that would give me problem after problem for me to practice?

  • @davidgamez-alvarez5701
    @davidgamez-alvarez5701 7 лет назад +1

    Why couldn't just start the first one as 1-pentene and reacted that with H20 and H2SO4?

  • @Alex_Van
    @Alex_Van 5 лет назад

    What about use of retrosyntesis method to make cyclic compunds?

  • @akramraza8361
    @akramraza8361 6 лет назад

    Best

  • @vlogsbydanielle4045
    @vlogsbydanielle4045 3 месяца назад

    bro is Noah Kahn if he was a chem god

  • @virgovirgo9367
    @virgovirgo9367 5 лет назад +1

    Hi there genius! Please help me solve a query in organic chemistry.... Please...
    "RUTIN" or "Rutoside" is a bioflavonoid with the formula C27-H30-O16, it is found in plants like Buckwheat and eucalyptus..
    My question is.. " Is it possible to manufacture "RUTIN" synthetically in a lab? without actually using the plant extracts.

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  5 лет назад

      I'm sure it is possible, we can synthesize almost anything, but I'm not good enough a synthetic chemist to come up with a pathway for something like that.

    • @virgovirgo9367
      @virgovirgo9367 5 лет назад +1

      @@ProfessorDaveExplains jeez! You replied to me... God bless me.. after all these subscribers, you got time to respond comments.. that's cool. That's pretty cool. Good luck..
      I'm Sam. We shall talk again if you believe in " chemical genysis" . 😐.
      I know it sounds crazy, see ya. Tada.!!

  • @AgamKaushiksowow
    @AgamKaushiksowow 7 лет назад +6

    how do i know which reaction to apply when doing organic conversions ?

  • @irfanashraf3848
    @irfanashraf3848 7 лет назад +1

    slaam sir

  • @ballaki
    @ballaki Год назад

    👍❤