Good news in the fight against pancreatic cancer | Laura Indolfi
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- Опубликовано: 8 июн 2016
- Anyone who has lost a loved one to pancreatic cancer knows the devastating speed with which it can affect an otherwise healthy person. TED Fellow and biomedical entrepreneur Laura Indolfi is developing a revolutionary way to treat this complex and lethal disease: a drug delivery device that acts as a cage at the site of a tumor, preventing it from spreading and delivering medicine only where it's needed. "We can make pancreatic cancer a curable disease," she says.
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My father just left yesterday. 2 weeks after diagnosis. It spread to his lungs and he opted to not do chemotherapy. He was suffering enough and wanted to go on his own terms. I was able to be with him in his final hours and tell him that I loved him, I am proud of him, he is brave, overcame so many obstacles, I hope you are proud of me and one day.....we will be re-united. Shortly after, he passed peacefully. This has taught me alot.....do not take life for granted, embrace your loved ones, tomorrow is not guaranteed, whatever riffs you have with loved ones....squash it, the status and materialistic stuff does not matter, be fearless and look to god and just live your life to the fullest with no regrets. I love you dad, Your son.....David Jr.
May your father rest in peace
I feel for you. My dad passed away in 2009 from this.
I'm so sorry for you lost 😔
Am sorry for your loss
May your father rest in peace...
Bless people for actually trying very hard to cure cancer
and the absolute worst type of it
I lost my mother to pancreatic cancer.. diagnosed in Sept 2018.. she passed May 19 2019..8 months.. my mother was strong.. physically and emotionally ...she became a widow at a young age..bared 7 children.. raised them on her own.. I watched her suffer with her diagnosis. My mother was miserable. I wanted to help her so bad... I couldn't do anything for her. I mean I could give her pain meds and meds for the relentless nausea..I tried to stay strong for her. She didn't want to see me hurting and I didn't want to cry in front of her. But she knew. I couldn't kiss her on her forehead without a tear falling. All I want to do is learn more.. read.. do research for better outcome of this disease. The statistics haven't changed in years. Knowing how deadly this disease is why hasn't there been any changes with research for so long. It's as if your on your own. I don't want to cover or mask the symptoms with narcotics.. I want results. She had a hard life and I'm saddened she had to go through what she did. No one deserves this suffering! No one!
Heidi Burks bless you in Jesus. Your mom has definately is in peace now.
Heidi: Bless you. I just lost my mother to cancer 6 weeks ago. I know, unfortunately, what you are talking about. Your mother was lucky to have you and she is always with you now. Just talk to her and she hears.
Heidi Burks hi, RIP ur mom!!🥺❤️ I have a question to ask you. My mom have the same cancer stage 4. I was wondering if your mom had chemotherapy or no?
Thank you Doctor. God bless all your efforts with this.
So let me get this straight, so far 14 people disliked it. What could be a reason to dislike such a great possible life saving cure?
We need this drug delivery technologies. The people whom dislike the video likely don't understand the concept. They need to be humble and don't express their negativity on subjects that they don't know.
I am one of those who DISLIKED this. This video is just another drug-promoting conference and talks about clinical trials that has almost no positive effect whatsoever in humans. My father has 2nd stage PC and getting Standard Care for 2 years. I have talked to countless doctors, nurses and watched tons of TEDx etc conferences. All I can say, PC will NOT be cured in OUR LIFETIME.
@@wadatamana But, like me, it can be beaten back into remission.
She downplays breast cancer as if is nothing lol 😆
@Two4Brew how did you achieve that?
Thank you so much for your work and sharing .
This is incredible tech and I'm so happy that you are here in Texas now. Excellent presentation.
This video is two years old and yet no updates on this treatment???
As a pancreatic cancer sufferer I can tell you the treatment and survival rate we get today is mot much better than it was this video was made
Now u are okay
M’y beautiful friénd Cécilia died at only 52 years old of That cancer..Still i cannot grasp it ..in 2 months
Merci..and bravo to your research team..hope is there..i miss her a lot 😞🙁miss her smille and her kindness ❤️
I am now 57 months, 3 weeks and 6 days post pylorus preserving Whipple for a Stage IB adenocarcinoma in the tissue of the head of that organ. That was followed by a chemo regimen from mid-July to mid-December 2015.
If any of y'all are interested, here's an article kind of updating the method about which she talks.: cancerres.aacrjournals.org/content/79/24_Supplement/B26
@@Two4Brew thanks, I was searching for it
@@user-vo9qz7ty2l You're welcome.
How are you doing? My uncle died from pancreatic cancer less than a year after diagnosis. It looks like your treatment worked great. Thankfully you caught it early
@@paolocannizzaro11 Thank you for sharing. I am now 73 months and 6 days post-Whipple, still no evidence of disease. I was very fortunate to have a Stage IB diagnosis.
I know how fortunate I am, as I was the 3rd of 4 cases in my family, only survivor. The other 3 were maternal side: Nonnie D'Orazio survived 5 months, Uncle Michael - 19 days and Cousin Kevin - 9 months. They were all found at Stage IV.
We need people like this lady. So much suffering on this planet. Too much
What symptoms he had?
My father was diagnosed with metastatic pancreatic cancer until the time we knew it already spread in his lungs as pleural fluid. Sometimes, he is having a difficult time breathing.
Doctors have started pallatative chemotherapy.
Just Hoping and Praying to God that everything goes well.
How is he now?
thank you so much🙏
Wonderful news!! Adjunctively providing more hope in the minds of the afflicted is powerful as well.
I sure hope this treatment works.
Amazing.
What is the current status of this type of treatment? Has it reached clinical trials?
I love her accent...so much that I have repeatedly listen to this video
Any updates please advise
Pancreatic cancer is also known as "silent killer", usually if its discovered its already too late.
How do I get in touch with her? Anyone knows how we can get this kind of treatment?
So painful to see your son with this horrible illness...He is now with God and let me mention, I missed him so much.
A hope!😊
This is amaze :)
This gives me hope as I am at risk for this particular type of cancer.
Does it run in your family? :/
Yeah, I've had 2 grandparents die from it. One from each side.
Demitry Khovokov how r u doing so far? Are fruits and vegetables & alcohol few of the reasons for this or is it just unknown as it’s how it starts to form? I’ve heard cbd might be able to help w this disease?
Scary. I had an aunt and uncle die from it in my dads side..
Is this available now?
If so, how do we gather more informations? Thanks in advance
I need a follow up to this please as the video wasn7 years ago. Very interested.
If I'm here because currently battling Pancreatic cancer or, if someone I care about is, thank you soooo much of all the "BAD NEWS" you are saying upfront. I really couldn't go pass that. No matter how GEAT " your good news are, when people are in crisis they don't want to hear the bad news they know it already. next time you or any TED speaker wants to get on stage and say something, be positive and mindful of your viewers of forever SHUT UP.
Could this be used for other forms of cancer like pulmonary or throat cancer?
Any develpments on this?
Where is this available
We need to start looking at cancer for what it is: a metabolic disease. This idea is great, and should be moved forward - but it still treats cancer as a genetic disease.
my mother had this last year. it is very difficult to treat.
Is this out? Please can someone tell me as I have a family member who needs this
please advice where we can get this, i have my relative suffering from this disease and we are ready to try this method.
Does this work when there are multiple small tumours ??
Life is so scary!
Sometimes it can be.
CHILLIN DILLAN
What do you mean?
Thats why I never support child birth.
my great grandmother died of cancer in pancreas !
good news... she's right in saying nothing has changed in screening and treating this cancer, which is strange
Subtitles please
My mommy died from this at age 48. I miss my angel😢 ppl please, take care of yourself, and dont eat sugars please. Dont drink too much coffee, because it spikes insulin constantly and dexydrate the cells from water. Get mr scan often
chamber of secrets
So sorry for your loss
Did your mom drink a lot of coffee?
chamber of secrets
So sorry for your loss
Did your mom drink a lot of coffee?
@@marquisgowdy5423 yes, like 5, 6 cups a day and a strong ones, i rarely sow her without coffee around.
Have you been staying healthy n happy? I know it’s hard because you lost your mom
@@marquisgowdy5423 my health isnt that great, but i hope it will be better. I had many loss in life in general but mom left me empty. I try to enjoy little things in life and keep it up. Thanks for asking, such sweet from you. God bless you my virtual friend🙏
Joan Crawford never had pancreatic cancer.
But this is a very informative talk.
at first glance at the thumbnail i thought it was anita sarkeesian
lol
I did, glad I clicked and learnt something instead.
I had NeuroEndocrine Cancer in 2012. Lost the tail of my pancreas and my spleen. Now, have " numerous" things growing in the front, not lg enough to biopsy. My surgeon says They are " probably" just cysts and I don't need a yearly MRI. I WANT a yearly MRI. What can I do?
@Marie W 777 You may friend me, and messenger me if you feel like sharing. I would like to talk to you if you like. Sickness makes for loneliness.
So what's her point? Have we cured it?
Has it reached this to India?
Thanks you so much 😍😍💃🏻🌹💃🏻😂😘😘😘😘😘😘😘😘😘😘😘😘👍
Tali'zorah Nar Rayya Voice Actor She Might Be ^^
This is ok fo pancreas classification ?
Ngl the Italians are killing it in the science world
Sounds like a good idea
I'm just 26 from i had pancreatitis 2 yr and than after 6 months I had pancreas psuedo cyst sugery it's been one year I'm takin enzyme pill every day three time and other vitamin pills still have complications and this month it's Dr double my dose still not get proper results this one of the worst disease and very expensive every thing pills and all please help me with financial or any ngo anyone and please scientist work on it please I'm done with this also I'm having fear of pancreatic cancer but don't have money diagnosis so I don't what gonna happen with me
What about metastasis? Many pancreatic cancers are diagnosed late, and are already metastasized. How will local chemotherapy solve anything here? Whipple surgery (removal of galbladder, duodenum, head of the pancreas and sometimes part of the stomach) is already being widely implemented to remove local pancreatic cancer tumors.
Is this the practice? I read american cancer society web, they said that when tumor spread, they would do chemo first then surgery. I think it should be surgery first, then chemo. My husband's little sister (44 year old) was just diagnosed with Pancreatic cancer this week. We are crying and looking for doctor whom is skilled enough to remove the cancer part as soon as possible.
Danping Li how is your sister in law? My father in law was diagnosed this week.
👏👏
how do i sign up for trails
Talk to doctor
@@jaclynpalencia2378 too late
Johnson videos why what happened?
Johnson videos do you have some sort of social media I can contact you on I need someone to talk to I have pancreatic cancer solid papillary carcinoma
Hpw does it feel knowing this is the least populer TED talk.
So 5 years ago and not known very broadly?
This seems similar in function to Gliadel wafers.
the simpler the better
What she says about why this cancer is so hard to treat makes sense. Very few blood vessels to transport medication.
The brain has very few blood vessels as well.
So to my way of thinking, you need to administer a product (not necessarily a drug) via the way that these organs absorb to function. Easier said then done.
There must be some brainiacs out there that can do it.
I think fasting and finding other ways to starve the cancers of their fuel would be the best way
My husband is suffering,i belongs to India can you please tell me if where can we get this treatment?
meri nani ko mouth cancer tha unhone R.K.HERBAL , freelance,Extinct Ayurvedic manuscript Research organization, se dava li or vo pehle din se hi swasth mehsus krne lage , thanks to R.K herbal Sabhi Ke bhalai Ke Liye Main Unka number de rahi hun vahan sirf 3 Dinon Mein cancer theek Hota Hai।7393985932
update about ur husband
the problematic here is that the chemicals aren't reaching properly the target so why not invent a locally active implant. But i think that there's a lot more in game than locally/not locally issues. Patients are also treated with radiotherapy (which is local) yet, they still die withing 5 years. this talk gives us a new perspective on a high mortality cancer but it's very simplistic and i hope people won't be fooled by it.
yeah. but maybe is using gamma rays in that area too destructive in that area. with the vital organs.
and you can't expect a detailed and deep thing in only 6 minutes.
cancer is already confusing enough.
I had a similar reaction to this video, and my comment got immediately removed, what a bunch of pansies. I wasn't even being harsh towards the talk either.
with something like cyberknife you can limit other organes damages. there are 20 min ted talk out there, she could have lengthened her talk. yes cancer is confusing (lololol) that's why you can't throw around "yay we have the solution for one of the worse cancer."
+Patchy i think it's more about a youtube glitch than TED deleting comment.
lookingforsure Idk but I know that I had to retype it, didn't get deleted or whatever happened this time at least.
Woooooooow
What is the pancreas atrophic
12 times more powerful sounds great and all, but it comes with different and possibly greater risks. Like, for example, the fact that this application of the drug will also deliver much more harmful doses of chemotherapy to the immediate surroundings of the tumor, as well the technical issues involved in making sure the device does not shift after surgery. Dosages may well be able to be increased/decreased depending on the situation, but I'm not sure how they plan on assuring that the device does not move.
Also, how quickly does the device itself dissolve inside the body? Wouldn't it be difficult to apply repeated doses to effectively kill the tumor's advance? There is a lot of information regarding this device that went undisclosed in this talk. I don't want to downplay the upsides to this new kind of treatment, it's just bothers me that so little was actually said.
Patchy Yeah so little being explained. But the idea is great
I thought the same thing. As well as all the information you stated, it bugs me that they dont actually tell us of a effective method of getting the treatment onto the tumor, for the reason surgery is so tough is because cancer cells dont like to stay together, and "flake" when handled, spreading them into more locations in the body. And then theres the issue of it potentially degrading away before it kills the cancer, or it affecting other healthy tissue. or reapplication. And how effective will this really be? Lets be generous and falsely state that it increases survival rates from 8% to 28%. Still an insanely high mortality rate, and an ineffective way to treat patients. the concept is good; the product (as of right now) doesnt look effective.
I think shes pretty up front about the fact that this delivery method is still a ways out from being the go to treatment. I watched my aunt die from pancreatic cancer. She lived 18 months after diagnosis. 6 months of chemo and sick all the time because of it and the remaining 12 months she lived in constant pain that got progressively worse the last 3 -1/2 in out of the hospital because they could only control the pain with I.V. drugs the last couple weeks in my grandmothers home under hospice care basicly comatose except when she'd moan and cry out in pain. I would pray for death pray that her suffering would end . even if this type of delivery method did nothing but ease the suffering of these patients. if it proves effective what else could something like this be used for are there other types of medicines that could be given this way that would improve there effectiveness while lessening harmful effects on the rest of the body? opioid medications for example, would this delivery method increase their effectiveness while decreasing chances of dependency? I'm far from an expert but in theory pretty interesting and if applicable fricking awesome.
"Lets be generous and falsely state that it increases survival rates from 8% to 28%. Still an insanely high mortality rate, and an ineffective way to treat patients. the concept is good; the product (as of right now) doesnt look effective."
Well, *probably* falsely stated, we have no idea that that is any more wrong than it is right.
For a moment let's assume that it increases survival rate after 5 years to 28%, as you said before.
Which treatment would you take?
If you'd do anything other than flip a coin, i'd say it's effective. It wouldn't be a cure, but anything that increases survival by even 1% over the current options is effective enough for my vote.
Jher Nifol I’m with you! If you’re one of the 20% that was saved, You’d definitely see the effectiveness!!!! Imagine that’s your wife, or mother, or father. Pretty effective for you, I’d say.
I wonder if the unusual diet I've followed for eleven years now might help cancer. For eleven years, I have lived more than 90% on fluid milk products, cow milk and cow cream. So every day more than 90% of my diet is some kind of milk--skim, 1%, 2%, whole--plus I sometimes buy pints of half-and-half or fluid whipping cream and drink them straight.
In my case the diet helps with an eye problem. To put it a little simply, if I eat solid, mixed food my eyes hurt and vision blurs; but if I follow the milk/cream diet, they feel and work okay.
I don't know all the reasons the milk/cream diet works, but I can explain one based on how my body feels. After you eat your food, the nutrients from the food go into your blood and circulate to the cells to nourish them. It seems to me that although my system does break up solid food it doesn't break it up as thoroughly as milk and cream, and hence when the nutrients from solid food reach the cells they clog and irritate the cells more than the nutrients from milk and cream, leading to pain and dysfunction. In my case the pain and dysfunction show up in my eyes, but I think for other people it might show up in other body areas and ways. I have the idea the milk/cream diet might therefore give relief to many diseases, including cancer, other eye disease, and fibromyalgia. I'm trying to get the medical establishment to test the idea, but that hasn't happened yet, so in the meantime I tell sick people about it thinking it might help them. So you might try the diet to see what it might do for you. It might not help at all, since I don't know of any cancer patient trying it. I tend to think it will help.
I got this idea from the Masai people of Kenya who live only on milk and beef from their cows. They do have one important rule for food mixing. They say "If a man eats meat and drinks milk on the same day, he is a glutton." So for me I must choose every day whether it will be a beef day or a milk day. I like beef, but prefer milk, so for me every day is a milk day. I really don't know what would happen if I had some beef days, but I've been quite content having them all be milk days.
Very interesting
Have you had cancer and helped/cured it with the milk/cream diet? Then you might personally know if your diet helps cancer. Other than that, I believe your diet is almost a super extreme modified form of a keto diet with extreme fat and protein consumption that many testify is amazing for the body.
This doesn't sound like a good idea. There is to much fat in that diet. Not to mention all kinds of hormones from the cattle products. Unless you're going organic.
💜 Jiddu Krishnamurti 💜 💜
😍 Pancreatic cancer is as serious as Jiddu Krishnamurti.
please turkish languege
6 years ago. why no use?
Alex Trebek died of pancreatic cancer.
Impression to me...they always treat like uncurable thing.
God is good! He will save us from cancer.
Then who at first gave cancer all children, women or men? Your idea of "God" seems to be a psycho. First, giving them cancer and making them suffer horribly. Please STFU.
@Marie W 777 Is it REALLY fair to blame someone because of their parents? Plus, certain mutations in your body can give you cancer even if you don't have any bad habits.
@Marie W 777 You have the right to believe in any fairy tale. I think your imaginary friend was not there when some of my acquaintances or family members were killed by cancer. There are many factors that lead to cancer or remission. Your imaginary friend was not among them.
@Marie W 777 Facts can be misinterpreted as rude. When doctors say that you are delusional, we tend to be defensive and that's understandable.
@Marie W 777 Religious people are mostly controlling and yet you have the audacity to call me controlling is null and void. 😂
What about nutrition? Poor nutrition created the problem so good nutrition can fix the problem
What's her accent?
Italian.
Italiana
ITALIAN
97th
Alan Rickman had prostate
Michael j fox is dead?
how do fight against something so opportunistic selfish and disgusting in character
Raw diet
I'm second!
I don't like the term Biomedical Entrepreneur. Sounds like a doctor who just wants to make money by marketing a new diet pill.
The average doctor would earn more than any entrepreneur unless this becomes revolutionary. Even then, unless she's a scumbag it wouldn't become a matter of money but of medical advancement.
I know. I just didn't like the term. It implies money as the primary motivation. I don't believe that that is her goal. Helping to evolve treatment should be first, THEN the money will follow as a secondary benefit. Perhaps Biomedical Pragmatist ..Evolvist. I don't know.
Sad that you did not like the term. I didn't like it too. but money is important for research. And if she manages to find a solution for this cancer, i don't care if she makes more money. Atleast shes earning it for the right reason. And, if her discovery goes a long way, the world will, atleast be freed of yet another life threatening malady.
Arpan Dutta Ya well this advancement is just a step, it's more of a technique to help than a solution for this type of cancer. I too have no problem with her making money from this device and I wish her all the money in the world if it saves just one person. Personally I think cancer research should be like the XPrize where an advancement like this should be financially rewarded and celebrated.
+Joxman2k Absolutely :)
why not just injecting it in the tumor with a needle.
or maybe that gene that stops cells from deviding in a needle and injecting it in the tumor.
I assume that procedure is even less invasive, locally and probably easier.
no seriously I want the opinion of someone with a little more knowledge on this subject....
randomly injecting the product with a needle in the tumor won't work. the product will be delivered too fast for the cells to absorb. they inject in the blood system because the blood will eventually go to the cell. that's the whole point of the video. they're inventing a cap that will locally and slowly distribute it's product into the cells.
From what I've read, one of the things that makes cancer surgery problematic is the spilling of cells. If you push a needle into a cancerous tumour, cells may be transferred from that needle to other areas of the body that needle touches.
terrible news in fashion tho
I have fatty pancreatic, I need to know how to remove the fatty out the pancreatic before it become cancer ♋️ thank you 🙏
Don't drink alcohol EVER. eat LOW FAT, AVOID PROCESSED, FRIED FOODS ALWAYS. EAT LOTS OF VEGETABLES. NO BUTTER, NO RED MEATS, NO SUGARS EXCEPT FOR FRUITS IN MODERATION. TAKE FISH OIL DAILY.
I'm also trying to prevent pancreatic cancer
Go on keto diet, regular scans and blood tests that look for cancer marker. Early detection is the best chance. Also do intermittent fasting, one meal a day or prolonged fasting, research about autophagy. Eliminate sugar, carbs and use of oil in foods (healthy fats like extra virgin olive oil, avocado and 100% butter are ok). Also try chaga mushroom, turmeric milk, broccoli sprouts in your diet.
Or just eat healthy.
If only we could make thick foreign accents curable. If only.
John Karavitis her accent isn't that bad. You just have to try and listen :)
Even Leonardo da Vinci would’ve had a tick foreign accent .
Why don’t you concentrate on her intelligence instead!
You should be ashamed of your simplistic and somehow
bias response.
John Karavitis that’s rude. She speaks beautifully.