Dear Armando, I can barely comprehend the hard work that may have gone in making a video like this -the graphics, accuracy of information, and the delivery of the presentation is immaculate. Your free videos have massively contributed to my knowledge base of basic sciences. Thank you. If I get somewhere in life, I will make a contribution to this channel.
YOU ARE SERIOUSLY SOOOO GOOD. You've helped me throughout high school and now I'm in dental school in my second year and you still continue to help me! Amazing videos and great work! So much appreciation. Thanks a ton!
Great video Armondo! One small error though. You are correct in saying that Prostaglandins and Thromboxanes are produced via the COX enzyme; however, Leukotrienes are produced via the Lipoxygenase enzyme not COX.
Dear Future prof, Armando Hasudungan Thank you for your kindness to show us your treasure. your "YOU TUBE" is beautiful. Your aesthetic feeling is huge like a ocean. I am so moved. Your attitude is scrub yourself,which is like "scrub a bathtub" thank you for your brightness. I always enjoy sun bath from U. from JAPAN
There are several factors in treating asthma naturally. One plan I found which succeeds in merging these is the Laken Chest Remedy (google it if you're interested) without a doubt the most useful resource i've heard of. Check out all the extraordinary information .
This was great, thanks, I have been researching "thyroid cure ayurvedic" for a while now, and I think this has helped. Have you heard people talk about - Yannabarn Vanish Thyroid - (Have a quick look on google cant remember the place now ) ? Ive heard some great things about it and my m8 got amazing results with it.
@@favourirobe5698 lmao you could have just said hey guys im trynna sell some bullshit. if you may be interested in wasting your money look up this bullshit. you could also have just said wtf that remedy is rather than refer to google and then to a source. lmao and the dude michiko mendola is either another account by you or another moron you asked to help you. He, as well, recommended googling it lmaooo. yall funny thumbing up ur own comments too bahahaha
Actually at 8:46, gluccorticoids don't actually directly promote osteoclast production. They do however inhibit osteoblasts like he mentioned, but in contrast to the increase in osteoblast apoptosis, the lifespan of osteoclasts is prolonged. Therefore, with longterm therapy, osteoclast numbers are usually maintained in the normal range while osteoblast and bone formation plummets. (Weinstein, Robert S. "Glucocorticoid-Induced Osteoporosis and Osteonecrosis.")
I love your videos. You make things sooo simple! We all appreciate you sharing your knowledge with us. You are helpful to many people and we all sincerely appreciate it!
Thank you for this clear overview. PS: I have always found the term "nonsteroidal anti-inflammatory drug" (NSAID) hard to come around, because it partly refer to a negative. It appear to me now - and please, anybody, correct me if I am wrong - that this reference in NSAID is the glucocorticoids, they are the ones that are both steroidal and anti-inflammatory.
No NSAIDS and Glucocorticoids are different Nsaids are non steroidal as the name suggests unlike Glucocorticoids Nsaids inhibits cox enzymes whereas Glucocorticoids inhibit Phospholipase A2 via lipocortin so both COX and LOX Enzymes are inhibited
Very lucid. Many of these recent pharm findings were not around when I attended health school 30 years ago. Keep making educational videos and may be ask for voluntary contributions in the future. Could even put on DVD for sale. A support remedial tutoring.
Why haven’t you mentioned that glucocorticoids such as prednisone are contraindicated in Diabetic patients. That’s so important especially in clinical practice. If possible please explain the mechanism of action with regards to how it increases sugar levels. Great content!!
Thanks for the in depth explanation, i use them from time to time to control my extreme eczema, it's an amazing creation, i couldn't be alive now without it, but it has a lot of cons!
thanks but there is one small mistake around 5:28 cox enzyme converts arachidonic acid to PG but not leukotriens actually leukotries are made from arachidnoic acid by 5-lipooxygenase enzyme! anyway thanks for the video!
Hi Grate Video, I did not understand it all but gone enough to know why i am having so many problems with prednisolone( taking prednisolone for 7 years)
📌MAKE THIS LECTURE STICK: FREE PRACTICE QUESTIONS HERE! 🎓
youmakr.ai/test-playground/questionnaire/673d4b3e859b9c170836f12d
Dear Armando,
I can barely comprehend the hard work that may have gone in making a video like this -the graphics, accuracy of information, and the delivery of the presentation is immaculate. Your free videos have massively contributed to my knowledge base of basic sciences. Thank you.
If I get somewhere in life, I will make a contribution to this channel.
Thanks mate. I appreciate it!
please dont stop doing videos like this!!! My univeristy doesnt explain anything. You are the reason why im passing. THANK YOU !!
the first 10 seconds are like "jsdifjhsdifhkdsjfikdsjfkdsjfödj" and then it gets - as usual - awesome!
you're so magical man. thanks
Can i get your number
10 secs it's like bbc hardcore
😂
YOU ARE SERIOUSLY SOOOO GOOD. You've helped me throughout high school and now I'm in dental school in my second year and you still continue to help me! Amazing videos and great work! So much appreciation. Thanks a ton!
But.. how.. how... HOW CAN YOU DRAW THAT WELL!?!?! You are AWESOME! THank you!
you are the best human being in the world, my hero
Great video Armondo! One small error though. You are correct in saying that Prostaglandins and Thromboxanes are produced via the COX enzyme; however, Leukotrienes are produced via the Lipoxygenase enzyme not COX.
Right. However, LT (Leukotrienes) will decrease because of inhibition of arachidonic acid
@@bhumiyadavbhu4889 Hmm, but won't that contrast with the load bearing gas powered defibrillator research done in Norse japan?
I'm from Brazil, more specifically from the state of Pará, your work is very productive. Congratulations.
Dear Future prof, Armando Hasudungan
Thank you for your kindness to show us your treasure.
your "YOU TUBE" is beautiful. Your aesthetic feeling is huge like a ocean.
I am so moved. Your attitude is scrub yourself,which is like "scrub a bathtub"
thank you for your brightness. I always enjoy sun bath from U. from JAPAN
Wow! 8 years old and still quite relevant. After watching enough of your videos, I'm happy to support you via Patreon. Keep up the good work!
One minor mistake: leukotrienes is not made by COX, rather by 5-lipoxygenase.
Gotta confuse the med school students right babe?
Hey Dudes from the Brony Cringe Video lol Rich Panini is everywhere now
Another minor mistake: "glucocorticoids" is NOT spelled "glucocoticoids" (without the "r")!
@@heydudesfromthebronycringe8422 so to avoid confusing them, let's teach them factually wrong science?
Yes
PLEASE MAKE MORE PHARM VIDEOS!!
There are several factors in treating asthma naturally. One plan I found which succeeds in merging these is the Laken Chest Remedy (google it if you're interested) without a doubt the most useful resource i've heard of. Check out all the extraordinary information .
This was great, thanks, I have been researching "thyroid cure ayurvedic" for a while now, and I think this has helped. Have you heard people talk about - Yannabarn Vanish Thyroid - (Have a quick look on google cant remember the place now ) ? Ive heard some great things about it and my m8 got amazing results with it.
@@favourirobe5698 lmao you could have just said hey guys im trynna sell some bullshit. if you may be interested in wasting your money look up this bullshit. you could also have just said wtf that remedy is rather than refer to google and then to a source. lmao and the dude michiko mendola is either another account by you or another moron you asked to help you. He, as well, recommended googling it lmaooo. yall funny thumbing up ur own comments too bahahaha
@@snekjuce so true man xD
Actually at 8:46, gluccorticoids don't actually directly promote osteoclast production. They do however inhibit osteoblasts like he mentioned, but in contrast to the increase in osteoblast apoptosis, the lifespan of osteoclasts is prolonged. Therefore, with longterm therapy, osteoclast numbers are usually maintained in the normal range while osteoblast and bone formation plummets. (Weinstein, Robert S. "Glucocorticoid-Induced Osteoporosis and Osteonecrosis.")
Absolutely phenomenal video regardless!
best tutorial , best explanation and best drawing . thanks
Thank you so much for your pharmacy videos! Greatly helped me a lot in surviving pharmacy school.
Oh, jeez. Fantastic drawings and great explanation! I've never seen anything like this.
Thank you! You’re making grad school a lot easier for a lot students!
Best video I watched about the topic, thank you!
I love your videos. You make things sooo simple! We all appreciate you sharing your knowledge with us. You are helpful to many people and we all sincerely appreciate it!
Timeless video. Thanks!
Armando thank you for making this amazing videos, much appreciated.
Thank you soo much!much love from Armenia
your videos are so helpful. a really good overview of glucocorticoids & the roles they play. keep the vids coming!
Good job! Im a French pharma student, you made my life a lot easier! Thanks for that
Thank you so much for making this video!!!
U helped me understand this in few minutes while I couldn't understand what the professor explained in 1h
U da best
This is a great video. I love the explanation. Thank you!
Thank you for this clear overview.
PS: I have always found the term "nonsteroidal anti-inflammatory drug" (NSAID) hard to come around, because it partly refer to a negative. It appear to me now - and please, anybody, correct me if I am wrong - that this reference in NSAID is the glucocorticoids, they are the ones that are both steroidal and anti-inflammatory.
No
NSAIDS and Glucocorticoids are different
Nsaids are non steroidal as the name suggests unlike Glucocorticoids
Nsaids inhibits cox enzymes whereas Glucocorticoids inhibit Phospholipase A2 via lipocortin so both COX and LOX Enzymes are inhibited
You saved my life dude cheers !!
Awesome work! Learning about Glucocorticoids in Robert Sopolsky’s book “Why Zebras Don’t Get Ulcers” led me to you🤩
Can we all appreciate the hardwork and the DIAGRAM ❤️❤️!!!
Loved the video.. ITS UMMMAZING!! ❤️
I have appreciated and enjoyed all your videos up till now. Please keep up the hard work !
Great artist. Great teaching video
Thank you for these videos! Some of my teachers did not know what they were doing! Thanks for clearing things up!
Thank you! Great visuals!
just so amazing ..may God protects you !
This was fantastic! Thank you!
Awesome video! Great drawing and explaining!
Fantastic. Extrememly helpful.
Stunning drawings and brilliant representation of information. Thank you!
So fantastic ! Thank you !
Best explanation ever
Very clear explanations and perfect drawings. I found it very useful so thank you.
Thanks armando❤
These efforts of yours are really appreciable. Please make more videos of pharma
Simply super ..ease of understanding
Excellent way of explaining! Great video
Correction: Glucocorticoids cause immunosuppression, but they do not reduce WBC count!
Very lucid. Many of these recent pharm findings were not around when I attended health school 30 years ago. Keep making educational videos and may be ask for voluntary contributions in the future. Could even put on DVD for sale. A support remedial tutoring.
Your drawing and teaching skills are mind blowing please make more videos regarding pharma and patho , Thankyou
هون ما بفهمو فارما و باثو
لازم تكملي الكلمة كلها عشان يفهمو
فارماكولوجي و باثولوجي
Thank you so much xx
That was really helpful!
Thank you for this short but really detailed information. It helped me a lot. thanks!
Amazing video,,, thank you.
life goal: understand what the fuck he is talking about at the first ten seconds , then talk like him
Really well explained.thank you so much!!!
amazing...good one Armando. .
great explanation
Why haven’t you mentioned that glucocorticoids such as prednisone are contraindicated in Diabetic patients. That’s so important especially in clinical practice.
If possible please explain the mechanism of action with regards to how it increases sugar levels.
Great content!!
Glucocorticoids increase gluconeogenesis, suppress glucose uptake and utilisation leading to hyperglycemia
@@ejirosuzzyakpomedaye6005 thank you!
Thanks a lot. Keep up the good work.
Great as usual. Thanks . very clear and informative.
thank you so so so so so so much
Thank you so much... You made it so easy❤️
thank you sir...... its very helpful
Great work
Thanks for the in depth explanation, i use them from time to time to control my extreme eczema, it's an amazing creation, i couldn't be alive now without it, but it has a lot of cons!
Your video is very helpful.
Great stuff! I like the paper and real marker look better than the whiteboard marker look
EXCELLENT VIDEO!!!
Thank you!
Great video!
Thank you!
Very clearly explained
Amazing! unique and gifted person. Keep it up!
Great video thank you.
Thank you so much for the video!!!
I wonder what we would do without your videos...!👌🙏
Thank very much to your work
😍😍💚
Thank you so much
such a great video...very helpful
#AWESOME!
You should put these notes up for sale afterwards.
Amazing. Thanks 👍
THANK YOU SO MUCH FOR THIS
Love it love it love it keep up the awesome work!!!!!
Words aren't enough to thank you, Armando. However, I must say: Thank you! So much....
Thank you very much that was very useful as usual ♥️
Great video!
Great video!! Thank you!
thank you so much great video
Amazing video
thanks but there is one small mistake around 5:28 cox enzyme converts arachidonic acid to PG but not leukotriens actually leukotries are made from arachidnoic acid by 5-lipooxygenase enzyme! anyway thanks for the video!
That was fantastic 👏👏
Thank you
fantastic
Hi Grate Video, I did not understand it all but gone enough to know why i am having so many problems with prednisolone( taking prednisolone for 7 years)
Thanks a lot ! straight forward and very comprehensive ! :D
You are amazing!
Thanks a lot
Helpful for this Nurse Practitioner student! Thank you :-)
thank u so much
thank you very much, the video you have made is really detailed and also very interesting to watch, all thanks to your wonderful artistic skills;)