Protein transport from ER to golgi to lysosome

Protein transport from ER to Golgi to lysosome - This protein transport lecture explains about the protein transport from ER to golgi bodies and then from golgi complex to lysozome through the endomembrane system of the cell. This explains the sequential process of how a protein synthesized in er lumen is chemically modified and then sorted through the golgi bodies and then to the lysozome. Lysozomal proteins are mostly hydrophobic enzymes that helps in degradation in chemical pathways.
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Thank you for watching the protein trafficking lecture on Protein transport from ER to golgi to lysosomes.

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Mam N linked glycosylation occurs in endoplasmic reticulum...and only the phosphorylation at 6th carbon of mannose in golgi complex..... Plz correct me If I m wrong😊😊

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[@kashmirapradhan6542]

Amazing explanation Sir
I would like to add a point sir
The vesicle which will be pinched off from Golgii will be coated with Clathrin 😊

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[@riderkidritam5634]

After becoming The Complete Vesicle, the CLATHRIN coat is dissociated from the vesicle & then the vesicle attaches with Early Endosome

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hi sir this is very useful thank u so much, i would like to know if u have a video about the proteins going to er from ribosomes and the signal recognition particle please thanks!

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It's Helpful

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[@avipandey1234]

Sir agar question puchega ki ,where sorting of lysosomal enzyme occurs to cis glogi network correct answer hoga ya trans golgi network

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[@boardexamgirl7713]

Can endoplasmic reticulum make vesicles by its own to transport its products to golgi apparatus?

[@KrishnaPatel-zb6nk]

By fusion with Cop2 Protein.

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thanks..........................

[@rabianoor1589]

Sir which products are produced by golgi apparatus? Please reply

[@shomusbiologyofficial]

Protein sorting and chemical modifications are done

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[@mangaldipde9274]

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[@shreyabharti1957]

Is hydrolase is protein or enzyme

[@slothbear921]

When the phosphate group is released and the late endosome is formed... where did the mannose sugar go?

[@sowjanyag2866]

i think mannose receptor go back to golgi complex by a vesicle to take up another enzyme

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[@sal6403]

Can you please explain anterograde and retrograde difference in pathway

[@shomusbiologyofficial]

Okay. Will do that in separate video

[@sal6403]

But I'm simple terms what is the difference?

[@ranjanjena9658]

Hi I am Sai and I have a question that where are lysosome synthesized?

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Nicee

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APESA was here :)

[@AmitKumar-bf9xg]

why phosphorylation of mannose residues is done here?

[@akshssmitasomani2594]

Maybe Phosphorylation serves as a molecular marker ,to transport it into its target organelles.

[@AmitKumar-bf9xg]

mannose 6 phosphate receptor is recycled..or not?

[@dankykang9853]

It is recycled

[@knowledgetime6791]

Krupàlupapupravacan

[@knowledgetime6791]

Ytt

[@AmitKumar-yo2qo]

Early lysosome do not come in the path from Golgi to Lysosome.

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Sound quality is low

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