How to interpret a PD-L1 immunostain

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  • Опубликовано: 31 янв 2025

Комментарии • 27

  • @inagalatchi2265
    @inagalatchi2265 11 месяцев назад +2

    amazing presentation! thank you very much!!

  • @danielaxhemalaj9192
    @danielaxhemalaj9192 Год назад +1

    Thank you very much professor for the detailed explanation!

  • @dri.satishrao5633
    @dri.satishrao5633 2 года назад +1

    Sanjay Precise as usual 👍👍👍

  • @anamikaabaddha1159
    @anamikaabaddha1159 3 года назад +1

    Thank you sir for the short, to the point presentation.

  • @firozsheikh3352
    @firozsheikh3352 5 лет назад +1

    Excellent video 🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻

  • @maharshidebnath7841
    @maharshidebnath7841 4 года назад +1

    Nice explanation sir

  • @homsitoufik3082
    @homsitoufik3082 2 года назад +1

    très bien

  • @radhikadoctor3848
    @radhikadoctor3848 4 года назад +1

    U r just awesome sir....thanks for the amazing video s

  • @rxvmt2538
    @rxvmt2538 5 лет назад +1

    Very helpful

  • @patriciacastillo9756
    @patriciacastillo9756 5 лет назад +1

    Excelente video! Thank you!

  • @pathologysimplified2821
    @pathologysimplified2821 6 лет назад +1

    Excellent

  • @sujathabalija2254
    @sujathabalija2254 4 года назад +1

    Thank you

  • @phungtieu8338
    @phungtieu8338 Год назад +1

    Hi,
    i was wondering in regards to staining sometimes it is reported as first line and than second line? are you able to confirm what does this mean?

    • @smlungpathguy
      @smlungpathguy  Год назад

      That refers to whether the immunotherapy drug is given as the first treatment for cancer (first line) or whether it's a treatment given after another treatment has been tried (second line)

    • @phungtieu8338
      @phungtieu8338 Год назад +1

      @@smlungpathguy thank you

  • @salemsulimanbaldi285
    @salemsulimanbaldi285 13 дней назад +1

    can you bound membrane staining and cytoplasm of PDL-1 expression?

    • @smlungpathguy
      @smlungpathguy  13 дней назад

      For lung 22C3 you should count membrane only

  • @hemantkumarchaudhari2188
    @hemantkumarchaudhari2188 2 года назад +1

    Patient having CPS 8 can take immunotherapy?

  • @steladesilva7743
    @steladesilva7743 5 лет назад +1

    Thank you so much

  • @DETODOUNPOCO33
    @DETODOUNPOCO33 5 лет назад +1

    Excelent video , im a med sutdent andi want to be a pathologist ,but , i am scared that the speciality wll not have a good future , because the AI , what can you suggest me about that ? thank you

    • @smlungpathguy
      @smlungpathguy  5 лет назад

      DETODOUNPOCO33 Thank you! Re: AI we are all wondering the same thing 😊, but at least in the near future I don’t think our jobs are threatened.

  • @apoorvshrivastav2186
    @apoorvshrivastav2186 5 лет назад +1

    What are the prospects for a patient with esophageal sq cell carcinoma. CPS=5

  • @zehraabidi6031
    @zehraabidi6031 2 года назад +1

    Sir how to interprete H score for the immunohistochemistry?kindly guide

    • @smlungpathguy
      @smlungpathguy  Год назад

      H-score is a common and well-known semiquantitative scoring system that takes into consideration staining intensity as well as the percentage of cells staining positively. H-scores can range from 0 (no expression) to 300 (3 + staining intensity in 100% of cells). Pubmed Baratchian and Mukhopadhyay, and you will find details in the references in that paper.

  • @AnkeetKumar
    @AnkeetKumar 4 года назад +1

    Will it always be like this .
    I mean is tumor cell always going to be bigger than macrophage. ?

    • @smlungpathguy
      @smlungpathguy  Год назад

      I would say most of the time tumor nuclei are bigger than macrophage nuclei