Part 1 - Patho-Physiology of Pruritus

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  • Опубликовано: 7 янв 2025

Комментарии • 16

  • @pratibhajp2171
    @pratibhajp2171 Год назад +2

    Thanks a lot for this detailed video, it's means alot to dermatologist

    • @sabhderma
      @sabhderma  Год назад +1

      My pleasure 😊 glad you found it helpful 😁

    • @roshanisk5189
      @roshanisk5189 Год назад

      Sir is there any classes for dermat pg students?

  • @ila6136
    @ila6136 6 месяцев назад

    Very helpful. Thank you very much. 🙏🏾

    • @sabhderma
      @sabhderma  5 месяцев назад

      Glad it was helpful! 😁😁

  • @namrathaputtur5964
    @namrathaputtur5964 2 месяца назад

    Sir please provide pdf for these slides

    • @sabhderma
      @sabhderma  2 месяца назад

      Hi, I am working on how to share the notes as these ppts have information from various sources. Will let you know when the notes would be available. Till then, keep seeing the videos please 😊😊

  • @drjaleena9918
    @drjaleena9918 Год назад

    Thank u

    • @sabhderma
      @sabhderma  Год назад

      Thanks and keep watching 😀

  • @jinishajain3829
    @jinishajain3829 11 месяцев назад +1

    I had a doubt sir, why does dermarophytoses cause itch where as p. Versicolour is usually non itchy.

    • @sabhderma
      @sabhderma  11 месяцев назад +2

      That is a very interesting insight. I don't know. But I may suggest that m furfur is a commensal, so maybe the immune cells do not elicit a stronger response to the fungi. While dermatophyte is an exogenous organism with greater immune mediated defense reaction, hence a strong itch response. Itching as a response evolved to rid the body of the pathogens. M furfur is a commensal. So maybe the itch response is not that strong. I hope this makes sense. Thank you for your comments ☺️☺️

    • @jamyangchoden1446
      @jamyangchoden1446 2 дня назад

      @@sabhderma p versicolor is not itchy because it stays within the stratum corneum where the nerve endings don’t reach

    • @sabhderma
      @sabhderma  2 дня назад

      @@jamyangchoden1446 good contribution. But what about dermatophytes that don't cross dej but are still very itchy?

    • @jamyangchoden1446
      @jamyangchoden1446 2 дня назад

      @@sabhderma unmyelinated C fibres reach up to granular layer of epidermis, maybe that’s why sir?

    • @sabhderma
      @sabhderma  День назад

      That is a good contribution. Okay, let's discuss. nerve fibres are found in all layers of the epidermis, so the sensations can come from all layers. P versicolor also penetrates sub-corneal layers in some patients, but is still not itchy. It may even induce a good immune response! While dermatophytes, even with little penetration can be very itchy. I think the reason lies in the host immune response to individual fungal species. P versicolor does not induce a significant immune response, may be they being a commensal and all. Activated immunity releases pruritogens leading to itching. I hope this is a useful explaination. let me know if these helps. Thank you for your comment. I might discuss pathology of itch in dermatophyte infections. it is interesting to understand and read. :) :D