I found this video very helpful! I also have viewed an easier step to combine steps 3 & 4. If, on your projection, the sign is 'S' then whatever is on the right is a dash and the left is a wedge. For 'R' signs what is on the right is wedged and the left is dashed! Helps so much!!!! Thank you for the video.
first, I have to say THANK YOUUUUUU!!! it is 3am, just a few minutes shy of 33hours till my Orgo exam #2. And thanks to this videoooo, I think I might just get another A!! Heres to RUclips for providing this platform for so many reasons, one of which, is for organic chemistry students to cry tears of JOYYYY!!! im so grateful right now, and also very dramatic lol. God bless you all in your exams! :D WOOOHOOO
Thank you! If this video was helpful, you may want to check out our month-to-month MOC membership for access to over 1500 quizzes, Flashcards, the Reaction Guide, and more. Check it out here: bit.ly/2YctxPb
Thank you very much sir , may God bless u ☺️ , u r an actual teacher. I am in awe and will be in awe to listen ulyou and working on your path. Thanks a lot.
By VV I am not sure if you are referring to flipping it in the plane of the page or outside the plane of the page. Bottom line: make sure the R,S values in your Fischer are the same as in your line diagram and you will be fine.
If the R,S values are reversed, that means the mirror image has been drawn (the enantiomer) so that's not quite correct. It is possible to draw the molecule in the VV form, but one would need to make sure that the R,S values are the same as for the starting material.
Hi, for carbon 2 (as an example), do you have to put the OH and H on the same side (either both on top or both on bottom) of the carbon chain? I put my OH on the top and my H on the bottom and I got that the OH should be dashed and the H should be wedged to obtain the R configuration.
What if the sawhorse projection looks like this: your front one looks like a V, but the back one looks like a upside down V (ie. Λ) ? Then what is the plane?
that means if we are only given fischer projection we will not be able to convert it in line diagrams accurately unless we are told that H OR OH IS COMING OUT OF PLANE OR INSIDE OR IN OTHER WORD CONFORMATION IS R OR S ,RIGHT?because when you started you were already aware of the fact that h is coming in front,please reply
really it is very helpful to me.I advise all the viewers who want to know basic of this type of questions to watch this video.and thank u so much sir.I have also an doubt sir- if there is another element instead of hydrogen then how to solve these,plz reply
If this were a sugar (with an aldehyde at the top) then that would be correct: "If OH is on the right, the carbon is R" is a good shortcut for sugars. However, in this case the CH3 (on the top, C-1) is a lower priority than the carbon attached to the OH (C-3) and so we get S, not R in this case.
I think what you showed is the long way. When a person can manipulate 3D objects in his mind, it is easy to form the 3D model from the Fischer projection
What I mean is, you drew your line diagram with the first carbon-carbon bond going diagonally top-right like this /\/\. I noticed that if you were to draw the like this VV the wedge/dashes and R,S, values are reversed. I'm sorry for bringing up such a bad question... =(
DrKatherine Baloch, ND Carbon #4 has no stereochemistry b/c it does not have four different atoms singly bonded to it. Carbon's #2 and #3 have S and R configurations respectfully.
To the people watching this in 2021, this method is incorrect. If you test it for yourself on a random sample problem, that shows you the correct line structure, you'll realize that getting the correct line structure relies on you guessing correctly; I'm referencing to step 3. Find a different video. It does, however, demonstrate how to properly find the R and S values for the given carbon 2 and 3 in the Fischer projection.
The video says (at 7:34) that we guess and then CORRECT IT LATER if need be. And if you watch the video, you see that this is EXACTLY WHAT IS DONE (at 9:59). There are two main approaches to converting Fischer projections to line diagrams. 1) Make a model, or 2) get really good at determining R/S on both Fischer and line drawings so you can easily interconvert the two. When I tell students to make models, they hear the voice of their parents telling them to eat their vegetables. So this approach shows an alternative way to do it. 1. Determine R/S on the Fischer 2. Draw out a line diagram with substituents 3. Assign stereochemistry (i.e. dashes/wedges) to the substituents (GUESSING stereochemistry). 4. Determine R/S on the Line diagram. 5. CORRECT any stereochemistry if the wrong R/S designation was applied, by doing a single swap. Learning how to QUICKLY determine R/S is a core skill that will be of enormous assistance when trying to answer, "enantiomers, diastereomers, or the same" type questions.
I found this video very helpful! I also have viewed an easier step to combine steps 3 & 4. If, on your projection, the sign is 'S' then whatever is on the right is a dash and the left is a wedge. For 'R' signs what is on the right is wedged and the left is dashed! Helps so much!!!! Thank you for the video.
thank you so much for your tip!!! I put the info into a clear table on my cheat sheet and I'm answering questions so much quicker now!
kiss me, fucking saved my ass, exams in a couple hours
this really made understanding this process so much easier. you are amazing thank you so much!!!
Thank you so much! After 8 years, a university student appreciating and using your lecture. Much love❤️
You're most welcome!
Thank you so much! My teacher had us flipping each molecule 10 times!
You are an angel and a savior! Thank you so so much! You explained to me what I could not understand in 2 hours of lecture flipping molecules
Thank you, I am very happy that you find it useful!
i did thanks a lot!
first, I have to say THANK YOUUUUUU!!! it is 3am, just a few minutes shy of 33hours till my Orgo exam #2. And thanks to this videoooo, I think I might just get another A!! Heres to RUclips for providing this platform for so many reasons, one of which, is for organic chemistry students to cry tears of JOYYYY!!! im so grateful right now, and also very dramatic lol. God bless you all in your exams! :D WOOOHOOO
I'm crying tears of joy! I don't want to use a model kit for my first exam.
Thank you so much😭 You re my angel. finally I could understand fisher projection
ur saving lives
monikawashere especially during corona :)
Thank you very much!!! I'm from Brazil and I could't find any videos in portuguese about this. Very helpful!
Thank you! If this video was helpful, you may want to check out our month-to-month MOC membership for access to over 1500 quizzes, Flashcards, the Reaction Guide, and more. Check it out here: bit.ly/2YctxPb
man, i passed thanks to you. Keep the good work and thank you!
You made this soo much easier for me! Thank you so much!!
Only video that helped me tbh so much simpler than the other ways
Thank you for making this fantastic video! So informative and helpful, you're amazing!
Thank you very much sir , may God bless u ☺️ , u r an actual teacher. I am in awe and will be in awe to listen ulyou and working on your path. Thanks a lot.
Orgo test tomorrow and you just saved my ass! Thank a lot!
By VV I am not sure if you are referring to flipping it in the plane of the page or outside the plane of the page. Bottom line: make sure the R,S values in your Fischer are the same as in your line diagram and you will be fine.
Genius!!! I owe you the world, thank you so much :)
Glad you found it helpful Natasha Donaldson !
I thought I will screw this part up though it seems easy, it was too prone mistakes. But after your video, I got all cleared. Thank you, sir!
Thank you so much!!! Crystal clear!!
Glad it helped!
I can't thank you enough for this man 💙
Life saver 🙌
Another wonderful video, I am so grateful to you! Thank you!
You are so welcome!
thanks, helped fill a gap in my DAT studies!
What I dont get is how do you know the position to draw the wedge vs dash...or does that matter?
This was very helpful. My solutions manual just wasn't clear enough for me haha.
Thank you so much. This video was extremely helpful!
the convention in the Fischer is that the "arms come out to hug you". In other words the horizontal bonds point out of the page.
Suppose you were to draw your line diagram differently (upside down) like this VV, I noticed that the wedge/dashes are reversed. Can you confirm?
Found it very useful, thanks
Glad to hear!
If the R,S values are reversed, that means the mirror image has been drawn (the enantiomer) so that's not quite correct. It is possible to draw the molecule in the VV form, but one would need to make sure that the R,S values are the same as for the starting material.
This was super useful! Thank you a lot
that is correct. if the atomic numbers are the same then you have to go further along to break the tie.
Great explanation still the best in the market
Hi, for carbon 2 (as an example), do you have to put the OH and H on the same side (either both on top or both on bottom) of the carbon chain? I put my OH on the top and my H on the bottom and I got that the OH should be dashed and the H should be wedged to obtain the R configuration.
What if the sawhorse projection looks like this: your front one looks like a V, but the back one looks like a upside down V (ie. Λ) ? Then what is the plane?
he said "let's do some surgery..."
one day man....
that means if we are only given fischer projection we will not be able to convert it in line diagrams accurately unless we are told that H OR OH IS COMING OUT OF PLANE OR INSIDE OR IN OTHER WORD CONFORMATION IS R OR S ,RIGHT?because when you started you were already aware of the fact that h is coming in front,please reply
he knew it was coming out because on a fischer projection, horizontal lines mean wedge and vertical lines mean dash
really it is very helpful to me.I advise all the viewers who want to know basic of this type of questions to watch this video.and thank u so much sir.I have also an doubt sir- if there is another element instead of hydrogen then how to solve these,plz reply
you posted it on my birthday
at 4:17 you say that C2 is S but my lecturer taught us that if OH is on the right then that C is R so I'm confused
If this were a sugar (with an aldehyde at the top) then that would be correct: "If OH is on the right, the carbon is R" is a good shortcut for sugars. However, in this case the CH3 (on the top, C-1) is a lower priority than the carbon attached to the OH (C-3) and so we get S, not R in this case.
Master Organic Chemistry oh right, thank you!!
you are a lifesaver! Thank you!!
God bless you!
I think what you showed is the long way.
When a person can manipulate 3D objects in his mind, it is easy to form the 3D model from the Fischer projection
Really helpful. Thanks😁👍
Very helpful. Thanks man.
thank you so much!! sooo helpful!!!!
Wouldn’t a fischer be eclipsed ? so when you draw it in paper you would have it not like you did.
You made my day
Thank you so much...These are so useful...:)
Thank you soooo sooo sooo much!!!!!!
Glad you found it helpful Kenya!
Very useful !!
LIFE SAVER!
Ajudou demais! thanks!
luv u dad
What I mean is, you drew your line diagram with the first carbon-carbon bond going diagonally top-right like this /\/\. I noticed that if you were to draw the like this VV the wedge/dashes and R,S, values are reversed. I'm sorry for bringing up such a bad question... =(
Thx alot.... You're the best^^
Not all heros wear capes!
thank you very much!!!
Muchas gracias, en español es muy difícil encontrar este tipo de explicaciones.
i can save time. thank u
Thanks man!
claudggel glad you found it useful!
thank you!
awesome!
why put 1 on OH?
Cebani Hlabisa because oxygen has high atomic number than carbon ,, so it has first periority..
thank you sir..
OMG thanks sooo much
thank you
Thankss Mannn😊
That canadian accent tho!
I can't anderstand why we say to S, R and to and R,S
2020 ?
August?
I love you.
nice
why are you all of a sudden deciding that the rotation is (S) with the fourth C?
DrKatherine Baloch, ND Carbon #4 has no stereochemistry b/c it does not have four different atoms singly bonded to it. Carbon's #2 and #3 have S and R configurations respectfully.
To the people watching this in 2021, this method is incorrect. If you test it for yourself on a random sample problem, that shows you the correct line structure, you'll realize that getting the correct line structure relies on you guessing correctly; I'm referencing to step 3. Find a different video. It does, however, demonstrate how to properly find the R and S values for the given carbon 2 and 3 in the Fischer projection.
The video says (at 7:34) that we guess and then CORRECT IT LATER if need be. And if you watch the video, you see that this is EXACTLY WHAT IS DONE (at 9:59).
There are two main approaches to converting Fischer projections to line diagrams. 1) Make a model, or 2) get really good at determining R/S on both Fischer and line drawings so you can easily interconvert the two. When I tell students to make models, they hear the voice of their parents telling them to eat their vegetables. So this approach shows an alternative way to do it.
1. Determine R/S on the Fischer
2. Draw out a line diagram with substituents
3. Assign stereochemistry (i.e. dashes/wedges) to the substituents (GUESSING stereochemistry).
4. Determine R/S on the Line diagram.
5. CORRECT any stereochemistry if the wrong R/S designation was applied, by doing a single swap.
Learning how to QUICKLY determine R/S is a core skill that will be of enormous assistance when trying to answer, "enantiomers, diastereomers, or the same" type questions.
Thx q
this makes no sense. you were all over the place!
You lost me at 11 mins... You changed it from R to S to R?
????
Explain more please
please help man!
🙏🙏😭😭😭😭😭😭😭😭😭😭😭😭😭
please reply
thank you so much!
thank you
Thank you