17:15. The good doctor meant to say phosphatidylcholine. Also part of the cell membrane depended upon methylation are phosphatidylserine and phosphatidylethanolamine. Although not dependent upon methylation, the other highly important constituent of cell membranes are cholesterol and cholesterol-sphingolipid rafts. Embedded proteins also play many essential parts of the cell membrane. Cell membranes are equivalent to the brain of an entire organism. Dr. Bruce Lipton has a lot to say about this subject. The exception to this rule is that lipids, especially long chained lipids, eicosanoids, which are 20 carbon chain lipids, docosanoids (22 Carbon chained lipids) and certain hormones like thyroid and steroid hormones do not need permission from the membrane to enter the cytoplasm. That goes for the nuclear membrane too.
I have 4 children(2 daughters and 2 sons). My sons were born with differences. Through the years, the geneticist tested to see if something could be found. In 2010, exome testing detected duplications of certain genes and several SNPs in my youngest son, which were X-linked. My oldest son wasn’t tested, since he didn’t have the same insurance. In 2015, another exome testing found another SNP, also X-linked…. Thing is, none of the snps found could explain why he had the physical anomalies, Developmental delays, and speech challenges. Both sons were followed by the same geneticist, the youngest being treated his entire life. Now he was also diagnosed as having CMT. The geneticist will retire by June and now I’m panicking because he is the only doctor who has been motivated and curious enough to find out what’s going on to give answers and to find solutions to my son’s condition. So maybe I can find out some more things with these tests. I haven’t ever used 23 and me nor the other companies mentioned. Do I have to?
I am broken-hearted that neither of you is seeing patients anymore... My son -sadly - has been a western medicine experiment for 14 months now with 7 hospital stays and 7 different medications that only made his seizures worse... I am a holistic health care practitioner and find myself legally blackmailed into poisoning my son with medications that just dont work. I am yet to find a fine practitioner like the two of you who would help my son (confirmed MTHFR, DAO, high homocysteine...) and address the methylation issues. I am yet to find a neurologist who will say his seizures are a symptom of methylation issue and NOT the epilepsy.
Thank you for this interview. It is terrific. It would also be great if the annoying chirping sound that is present throughout the dialogue could be filtered out. Thanks again, Robert
Great interview. It's hard to know how one does on a ketogentic diet until having done it for at least a month. I felt terrible on it and heard that others took only days or a few weeks at most to adjust to it. For me it took over a month, but when it started working it was incredible. I ordered the Dirty Genes audiobook after listening to Mutzel's interview - great content there and here as well - congrats to you both. In that book I think that Dr. Lynch said that he gave his son tyrosine and that helped him with forgetfulness re: having sports equipment lying around and with late morning sleep-ins. Was the tyrosine or tryptophan?
You are correct. He gave his son tyrosine but not everyday. If you are going to supplement with either, I would recommend Pure Encapsulations brand. (I did not do well on strict keto either.)
P.S. Have you had your 23andme done? PureGenomics and (I think) Strategene will tell you if you would benefit from tyrosine (speaking from experience with it).
That's a great point Todd. It's a reminder that we MUST focus on understanding how these lifestyle changes impact us on a personal level, and adjust based on that.
Great video, very educational in content and also, in reminding us to keep things in perspective in relation to our MTHFR (and other gene) status. Its not all doom and gloom as we are sometimes led to believe, there are so many things we can do to improve our health, regardless of our genetic makeup. Well done to both of you
The idea that our Paleolithic ancestors living in verdent areas of the world ate a lot of vegetables and fruits is pretty goofy. Every vegetable and fruit you see in the supermarket today is a cultivar. The artichoke today as opposed to the artichoke in Spain and the Middle East 900 years ago are two very different things. Apples and blueberries today are entirely different from apples and blueberries even two thousand years ago, not even that! High in the mountains of New Mexico, while many times hiking, I tried all of the wild fruit and berries I could find. They are beyond bitter! Humans did not sit down and have these as staples in their diet. No indigenous people today rely upon vegetables. In tropical areas, fruit is consumed as a small part of their diet.
Are the Tests for sensitivity to gluten/ cows pro sensitive enough to pick out the problems. And what r these tests. Can u reply asap. Iv heard of urine/stool/blood - IgG /IgE r these the best ones to use?
17:15. The good doctor meant to say phosphatidylcholine. Also part of the cell membrane depended upon methylation are phosphatidylserine and phosphatidylethanolamine.
Although not dependent upon methylation, the other highly important constituent of cell membranes are cholesterol and cholesterol-sphingolipid rafts. Embedded proteins also play many essential parts of the cell membrane.
Cell membranes are equivalent to the brain of an entire organism. Dr. Bruce Lipton has a lot to say about this subject. The exception to this rule is that lipids, especially long chained lipids, eicosanoids, which are 20 carbon chain lipids, docosanoids (22 Carbon chained lipids) and certain hormones like thyroid and steroid hormones do not need permission from the membrane to enter the cytoplasm. That goes for the nuclear membrane too.
What is that ticking noise?
This interview is so enlightening! I am going to listen to it again for sure! Thank you for sharing your wealth of knowledge.
I have 4 children(2 daughters and 2 sons). My sons were born with differences. Through the years, the geneticist tested to see if something could be found. In 2010, exome testing detected duplications of certain genes and several SNPs in my youngest son, which were X-linked. My oldest son wasn’t tested, since he didn’t have the same insurance. In 2015, another exome testing found another SNP, also X-linked…. Thing is, none of the snps found could explain why he had the physical anomalies, Developmental delays, and speech challenges. Both sons were followed by the same geneticist, the youngest being treated his entire life. Now he was also diagnosed as having CMT. The geneticist will retire by June and now I’m panicking because he is the only doctor who has been motivated and curious enough to find out what’s going on to give answers and to find solutions to my son’s condition. So maybe I can find out some more things with these tests. I haven’t ever used 23 and me nor the other companies mentioned. Do I have to?
Excellent! Thank you.
I am broken-hearted that neither of you is seeing patients anymore... My son -sadly - has been a western medicine experiment for 14 months now with 7 hospital stays and 7 different medications that only made his seizures worse... I am a holistic health care practitioner and find myself legally blackmailed into poisoning my son with medications that just dont work.
I am yet to find a fine practitioner like the two of you who would help my son (confirmed MTHFR, DAO, high homocysteine...) and address the methylation issues.
I am yet to find a neurologist who will say his seizures are a symptom of methylation issue and NOT the epilepsy.
try this tool: www.ifm.org/find-a-practitioner/
Thank you for this interview. It is terrific. It would also be great if the annoying chirping sound that is present throughout the dialogue could be filtered out. Thanks again, Robert
Unfortunately nothing we can do now, but thanks for that feedback Robert. Will be on the lookout in the future!
Amazing information. 2 great brains
Great interview. It's hard to know how one does on a ketogentic diet until having done it for at least a month. I felt terrible on it and heard that others took only days or a few weeks at most to adjust to it. For me it took over a month, but when it started working it was incredible.
I ordered the Dirty Genes audiobook after listening to Mutzel's interview - great content there and here as well - congrats to you both. In that book I think that Dr. Lynch said that he gave his son tyrosine and that helped him with forgetfulness re: having sports equipment lying around and with late morning sleep-ins. Was the tyrosine or tryptophan?
You are correct. He gave his son tyrosine but not everyday. If you are going to supplement with either, I would recommend Pure Encapsulations brand. (I did not do well on strict keto either.)
P.S. Have you had your 23andme done? PureGenomics and (I think) Strategene will tell you if you would benefit from tyrosine (speaking from experience with it).
Thanks J lewis -- I haven't done it yet but I plan to eventually. Strategene will definitely be a first place for me to look.
That's a great point Todd. It's a reminder that we MUST focus on understanding how these lifestyle changes impact us on a personal level, and adjust based on that.
Great video, very educational in content and also, in reminding us to keep things in perspective in relation to our MTHFR (and other gene) status. Its not all doom and gloom as we are sometimes led to believe, there are so many things we can do to improve our health, regardless of our genetic makeup. Well done to both of you
The idea that our Paleolithic ancestors living in verdent areas of the world ate a lot of vegetables and fruits is pretty goofy. Every vegetable and fruit you see in the supermarket today is a cultivar. The artichoke today as opposed to the artichoke in Spain and the Middle East 900 years ago are two very different things. Apples and blueberries today are entirely different from apples and blueberries even two thousand years ago, not even that!
High in the mountains of New Mexico, while many times hiking, I tried all of the wild fruit and berries I could find. They are beyond bitter! Humans did not sit down and have these as staples in their diet. No indigenous people today rely upon vegetables. In tropical areas, fruit is consumed as a small part of their diet.
Are the Tests for sensitivity to gluten/ cows pro sensitive enough to pick out the problems. And what r these tests. Can u reply asap.
Iv heard of urine/stool/blood - IgG /IgE r these the best ones to use?
captions control missing.
i have it
Pomc ❤. Acth- Msh. ❤
The noise is annoying for sure. Trying to hang in there 😂
Interesting vid, thank you very very much. (is that a little mouse tap dancing in the background? 😉)
Mimi lovehealth it's an African lap clapper that's hanging out with the doc
Frank J Rozatti lap clapper? dirty genes.