Mine is high also and so is the ratio too bad no former Drs don't open a website for people to ask questions when your regular Dr doesn't or don't care
In 3 months, kappa-lambda ratio went up from 3.4 to 20. Kappa is 198. Could this be defined as a light chain escape episode? All other test results are good. No M-spike detected.
One example was not explained -- What if both light chains are high. But ratio is normal. K: 65 L: 44 Ratio: 1.47 -- Serum protein electrophoresis does not suggest a monoclonal pattern.
You bring up light chain escape which is not a real phenomenon, it is undetected hook from tbe assay used meaning the flcs were always high, just hooking
Extremely educational and helpful,thank you❤
Phenotype: CD38, CD138, lambda light chain, CD56 (partial), CD117 (partial). Monoclonal gammopathy, IgA lambda. 13q-/-13: Monosomy 13 detected, 1p32/1q21: Duplication of 1q detected, IgH (14q32): IgH rearrangement detected.
This webinar was extremely helpful in understanding my biopsy results.
Wish you all the health in the world ❤️
Excellent lecture! Thank you!
Excellent, thanks!
Is there a better time of day to have this test?
My Kappa free light chain is at 29.3 the lambda is 25.2 and the ratio is 1.16 what d o rd that mean
Mine is high also and so is the ratio too bad no former Drs don't open a website for people to ask questions when your regular Dr doesn't or don't care
Is there a journal version of this?
In 3 months, kappa-lambda ratio went up from 3.4 to 20. Kappa is 198. Could this be defined as a light chain escape episode? All other test results are good. No M-spike detected.
Can I join web maner
One example was not explained -- What if both light chains are high. But ratio is normal.
K: 65 L: 44 Ratio: 1.47 -- Serum protein electrophoresis does not suggest a
monoclonal pattern.
This is most likely a reduced glomerular filtration rate and both kflc and lflc are being retained at higher rates
can you have a normal free light chain ratio but you have a small about of M protein
Of course. Abnormal ratio is around 70-90% specific to presence of monoclonal proteins
@@yogamon it was for a family member, M protein went away, with no change in treatment hopefully it says away
Kappa/lambda ratio is normal but kappa and lambda free chain assay value is high....???
You bring up light chain escape which is not a real phenomenon, it is undetected hook from tbe assay used meaning the flcs were always high, just hooking