Transplantation and Graft Rejection (Immunology Lecture 09)

Learning Objectives:
Definition of Transplantation
Types of Transplant
Solid Organ Allograft Rejection
Acute Graft Rejection
Chronic Graft Rejection
Hyperacute Graft Rejection
Pathways of Allograft Rejection
Direct Pathway
Indirect Pathway

[@maksudulislamtonu2876]

This is helpful. Kudos to you

[@nikhilthapa2012]

Thank You. Extremely Helpful 😊

[@toufiqenam9516]

Excellent video.keep it up sir👍👍👍👍

[@Cravhingz]

Thank you so much, sir!

[@aasmaismail9709]

Very helpful video sir👍

[@faatimahhakim6088]

Extremely helpful. Thank you.

[@RabiulHaque]

Thank you for your feed back. Take care and stay safe. :)

[@waqaryousaf2120]

Hi, I am writing an essay on transplant rejection I was wonderiing how best to format it. Hyperacute, acute and chronic rejection and talk about the main phenotypes or antibody mediated and T cell mediated and reference too difrence amongst stages.

[@tejaswishenoy3786]

Since Tcells always require MHC to detect the antigen can the donor MHC protein triggering the recepient's Tcells be considered super antigens??
I mean how can recepient Tcells directly detect the donor MHC ??

[@fatimachaman6615]

Thank you so much sir

[@subrinamasoodi6153]

Excellent

[@yohani8302]

Hi Dr Rabiul
very interesting video, thank you !
I have a question (for example a kidney): Does the movement of CPA's cells and lymphocytes happen solely within the recipient's bloodstream and causes damage inside the kidney, or does it also occur externally and the transplanted organ, in the abdominal cavity, is attacked on the capsule with the same pathways (direct/indirect)?

[@user-yi2re8nq5s]

Sir, why Cytotoxic T-cells cannot participate in indirect pathway but can do so in direct one?

[@gulfamjameel1703]

CD8+ T-cells recognise MHC Class-1 molecules.. MHC-1 molecules are present on every cell and represent the products made by that cell. This system is to check whether the cells are normal, infected, or cancerous. In Direct pathways, the CD8+ cells get mad due to the foreign cells in the body, not because of the products present on their MHCs.

[@raahimafarhan6635]

jazak Allah

[@RabiulHaque]

Thank you for your feedback. Take care and stay safe. Best wishes from Bangladesh. :)

[@shaikh.700]

Thank you

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. If possible do share the lecture with your friends. :)

[@shaguftamureed4637]

sir can you share the cardiopulmonary transplantation lecture

[@koushalyajb2894]

Thank you sir

[@RabiulHaque]

Thank you for your feedback. Take care and stay safe. Best wishes from Bangladesh. :)

[@mgsaini8738]

Good sir

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@kiransulba9559]

Thanku sir 🙏

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed.

[@davidkuledjawa8447]

Excellent workdone sir

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@mzeevuai]

thanks sir

[@RabiulHaque]

Thank you for your feedback. Take care and stay safe. :)

[@MehediHasan-gy8uz]

Mhc molecule always present in cell surface???? Why all are talking about apc mhc molecule, is not there any other cell in grafted tissue except apc?😂
And recipient t cell is recognise mhc molecule of donor??? Or peptide of mch molecule of donor?????? Clear these

[@aasmaismail9709]

Very helpful video sir👍