Macrolides | Structure | Mechanism | Resistance | Interaction | Adverse Effects

#pharmacology #antibiotics #drugs #macrolides #azithromycin #clarithromycin #erythromycin #microbiology
Macrolies inhibit bacterial protein synthesis. The mechanism of action of macrolides revolves around their ability to bind the bacterial 50S ribosomal subunit causing the cessation of bacterial protein synthesis.
Like any other antibiotic, macrolides carry a certain level of risk from typical adverse effects like nausea, vomiting, abdominal pain, and diarrhea. Abdominal symptoms are largely the result of macrolides being motilin agonists causing an increased risk of gastrointestinal upset and side effects.

[@sejalnalawade4497]

Thank you , great explanation !

[@medlecto5507]

Glad it was helpful! ✨