If you found this explanation a little too confusing, no worries, I have a blog post that breaks it down even further. www.familyhistoryfanatics.com/post/visual-phasing-2-siblings
This video was great! I’ve been feeling like I’ve “done it all” with my DNA at this point and I’ve been feeling like “what’s next?” I still have so many brick walls. So I’m excited to try this!
I just found out that your brother is one of my favorite professors! I am in his Science and Religion course, he brought up the possibility that a child could have parents, a sperm donor, an egg donor, a mitochondrial donor, and a surrogate mother. What a crazy genealogical/DNA situation. Also crazy is that I see the resemblance now that I know you guys are brothers.
I read through the blog post and watched the video, but I'm stuck at the point of selecting a match for comparison to the two siblings. The blog post says to use a 1C, 1C1R, or 2C that is connected to a specific grandparent line. How would I have a 1C that is connected to a specific grandparent when by definition, I share two grandparents with a 1C? Do you mean a 1/2 1C? How would I know whether the 1C matches to the maternal grandmother or grandfather, as shown in the example? I'm sure there's something I am missing.
I may be wrong, but as you share only on average 12.5% DNA with a 1C, you can use the segments where you fully match, half match and don't match to help you
Hi, am I understanding this right way: in the case of two siblings, their mother and their paternal grandmother tested, applying this process to the siblings and their paternal granny, it will be possible to fully phase their paternal part of the chromosomes? And for their mothers part additional matches needed to phase, like her cousins?
Traditional Visual Phasing requires three or more siblings. When you have a parent, many platforms will automatically separate your DNA matches to maternal or paternal. (Ancestry does this for my matches but my wife does not have tests for her parents, so she has to manually separate her matches). So.. you don't necessarily need to do phasing when you have the DNA test of a parent.
I have a couple of questions. If you only share a small amount of DNA (22%) with a sibling, does that definitely mean you only have one parent in common? Would it be a good idea to upload the information to GEDmatch or should the siblings retest with a different company? Would it help to have another sibling do a test?
According to the Shared cM tool, 22% falls into a mostly likely half-sibling category dnapainter.com/tools/sharedcmv4. Having another sibling test would be very helpful to figure out who is related to whom. You don't necessarily need to test with another company. Using GEDmatch is a great tool. But for your question, test another sibling, and then test parents, aunts, uncles, siblings, etc. You have an unexpected paternity issue. You might want to watch this video as well ruclips.net/video/oT4dfQ7KT3A/видео.html
I have a question concerning the full match regions and I'm not exactly sure how to word it, so I hope it makes sense. I know that oftentimes there are some green lines that get ignored in the half match regions. On some of the full match regions between my father and my uncle, there is a thin yellow line. So, do I count those as recombination points or do I just ignore them like is done for the lines on the half-match sections?
You should be able to click the box at the bottom to only show FIR regions and that will tell you if the computer is interpreting it as a FIR or two HIR. It all depends on how close together two yellow marks are.
I'm pretty sure I didn't understand any of that. The leaps of logic you are taking are just out of my reach. I'll try reading the blog post. I think the problem is I know nothing about gedmatch and it intimidates me.
We have a lot of tutorials on Gedmatch, so start there. This video is an alternative to Visual Phasing which I covered in a 4 part series. Did you see that? It begins with this video ruclips.net/video/fHZGdifd4KY/видео.html
Andy - question - if you use this 2-sibling approach to resolve the grandparents (using VP) does this result just apply to one or two siblings? If you have a total of five siblings (including yourself) would you get "different results" (in terms of the grandparent placements along the chromosomes) depending on which sibling pair you use? I hope these questions make sense. THANKS!
The question makes great sense, The phasing with three or more siblings would be different and likely more accurate than 2 siblings, which is why that's preferred. The 2-Sibling approach is best for those who can't do 'traditional' visual phasing.
I have testd my sister, so I am exciited that I can use this. We also have a half-brother who tested at 23&Me but he does not want to upload to Gedmatch. Is there a way I can incorporate his shared paternal DNA with my sister and me?
Visual Phasing is an advanced genetic genealogy technique. If you're new to genetic genealogy, don't start here. Also, this is an alternative to the Visual Phasing 4 part series we discussed beginning with this video. ruclips.net/video/fHZGdifd4KY/видео.html
If you found this explanation a little too confusing, no worries, I have a blog post that breaks it down even further. www.familyhistoryfanatics.com/post/visual-phasing-2-siblings
If either parent is tested then the RP's can then be identified as being from either the paternal or the maternal side as well
Do you have email?
This video was great! I’ve been feeling like I’ve “done it all” with my DNA at this point and I’ve been feeling like “what’s next?” I still have so many brick walls. So I’m excited to try this!
How did it go?
I just found out that your brother is one of my favorite professors! I am in his Science and Religion course, he brought up the possibility that a child could have parents, a sperm donor, an egg donor, a mitochondrial donor, and a surrogate mother. What a crazy genealogical/DNA situation. Also crazy is that I see the resemblance now that I know you guys are brothers.
You did great asking the questions we gave you in his class. When we got together this summer, my eldest brother had a belly busting laugh. Thanks.
I read through the blog post and watched the video, but I'm stuck at the point of selecting a match for comparison to the two siblings. The blog post says to use a 1C, 1C1R, or 2C that is connected to a specific grandparent line. How would I have a 1C that is connected to a specific grandparent when by definition, I share two grandparents with a 1C? Do you mean a 1/2 1C? How would I know whether the 1C matches to the maternal grandmother or grandfather, as shown in the example? I'm sure there's something I am missing.
I may be wrong, but as you share only on average 12.5% DNA with a 1C, you can use the segments where you fully match, half match and don't match to help you
No, I meant to say half 1C
Hi, am I understanding this right way: in the case of two siblings, their mother and their paternal grandmother tested, applying this process to the siblings and their paternal granny, it will be possible to fully phase their paternal part of the chromosomes? And for their mothers part additional matches needed to phase, like her cousins?
Traditional Visual Phasing requires three or more siblings. When you have a parent, many platforms will automatically separate your DNA matches to maternal or paternal. (Ancestry does this for my matches but my wife does not have tests for her parents, so she has to manually separate her matches).
So.. you don't necessarily need to do phasing when you have the DNA test of a parent.
I have a couple of questions. If you only share a small amount of DNA (22%) with a sibling, does that definitely mean you only have one parent in common? Would it be a good idea to upload the information to GEDmatch or should the siblings retest with a different company? Would it help to have another sibling do a test?
According to the Shared cM tool, 22% falls into a mostly likely half-sibling category dnapainter.com/tools/sharedcmv4.
Having another sibling test would be very helpful to figure out who is related to whom. You don't necessarily need to test with another company. Using GEDmatch is a great tool. But for your question, test another sibling, and then test parents, aunts, uncles, siblings, etc. You have an unexpected paternity issue. You might want to watch this video as well ruclips.net/video/oT4dfQ7KT3A/видео.html
Can this be done with two half siblings?
I have a question concerning the full match regions and I'm not exactly sure how to word it, so I hope it makes sense.
I know that oftentimes there are some green lines that get ignored in the half match regions. On some of the full match regions between my father and my uncle, there is a thin yellow line. So, do I count those as recombination points or do I just ignore them like is done for the lines on the half-match sections?
You should be able to click the box at the bottom to only show FIR regions and that will tell you if the computer is interpreting it as a FIR or two HIR. It all depends on how close together two yellow marks are.
@@FamilyHistoryFanatics Ok, thank you. I will try that.
I'm pretty sure I didn't understand any of that. The leaps of logic you are taking are just out of my reach. I'll try reading the blog post. I think the problem is I know nothing about gedmatch and it intimidates me.
We have a lot of tutorials on Gedmatch, so start there.
This video is an alternative to Visual Phasing which I covered in a 4 part series. Did you see that? It begins with this video ruclips.net/video/fHZGdifd4KY/видео.html
Andy - question - if you use this 2-sibling approach to resolve the grandparents (using VP) does this result just apply to one or two siblings? If you have a total of five siblings (including yourself) would you get "different results" (in terms of the grandparent placements along the chromosomes) depending on which sibling pair you use? I hope these questions make sense. THANKS!
The question makes great sense, The phasing with three or more siblings would be different and likely more accurate than 2 siblings, which is why that's preferred. The 2-Sibling approach is best for those who can't do 'traditional' visual phasing.
I have testd my sister, so I am exciited that I can use this. We also have a half-brother who tested at 23&Me but he does not want to upload to Gedmatch. Is there a way I can incorporate his shared paternal DNA with my sister and me?
If you or your sister tested at 23andMe, then you could use the data from 23andMe since they provide you FIR and HIR regions.
boy do i feel stupid
Visual Phasing is an advanced genetic genealogy technique. If you're new to genetic genealogy, don't start here. Also, this is an alternative to the Visual Phasing 4 part series we discussed beginning with this video. ruclips.net/video/fHZGdifd4KY/видео.html