Human Papilloma Virus (HPV) 🦠 | Properties | Replication
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- Опубликовано: 6 сен 2024
- #virology #microbiology #virus #humanpapillomavirus #HPV #cancer #warts #tumor
HPVs (human papillomaviruses) infect epithelial cells and their replication cycle is intimately linked to epithelial differentiation. There are over 200 different HPV genotypes identified to date and each displays a strict tissue specificity for infection. HPV infection can result in a range of benign lesions, for example verrucas on the feet, common warts on the hands, or genital warts. HPV infects dividing basal epithelial cells where its dsDNA episomal genome enters the nuclei.
At the molecular level, cancer progression is due to increased expression of the viral oncoproteins E6 and E7, which activate the cell cycle, inhibit apoptosis, and allow accumulation of DNA damage.
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In normal replication proces ,do u say abrasion or abrian
abrasion