The Doctor who Deceived Cancer Patients for Fame

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  • Опубликовано: 30 июн 2024
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    In 2006, a revolution emerged that held the promise to change cancer research. Being considered as a major breakthrough, this discovery promised to deliver the most effective drugs for every cancer patient. The scientists behind this incredible discovery though.. deceived everyone.
    Cancer is one of the deadliest diseases in the world. Although there has been significant progress in the development of cancer treatments, there is no definite cure for all cancers. The reason for this is that cancer is a highly divers disease and, thus, every cancer patient could need different drugs. Personalized medicin (or precision medicine) is a field of research where the treatment is customed towards the individual patients. Anil Potti was a researcher at Duke university who developed a tool to predict the most effective treatment based on the activity of genes. Joseph Nevins, Anil Potti's mentor and Potti published what seemed like groundbreaking research. However, two data scientists called Kevin Coombes and Keith Baggerly found inconsistencies in Potti's predictions. Over time, other scientists spoke out against these predictions until it was revealed that the used data was altered and manipulated. This is the story of a man who deceived the world and brave scientists who uncovered the truth.
    References:
    Coverage by 60 Minutes: www.cbsnews.com/news/deception-at-duke-fraud-in-cancer-care/
    Perez story: www.cancerletter.com/free/20150109_1/
    www.science.org/content/article/potti-found-guilty-research-misconduct
    www.issuu.com/thecancerletter/docs/duke_scandal_timeline_73c0d0f1934f29
    www.washingtonpost.com/news/morning-mix/wp/2015/11/09/scientist-falsified-data-for-cancer-research-once-described-as-holy-grail-feds-say/
    www.nature.com/articles/nj7396-137a
    www.jstor.org/stable/27801549
    www.science.org/content/blog-post/duke-potti-scandal-inside
    cancerletter.com/free/2015012...
    Images:
    Some pictures were derived from Servier Medical Art by Servier. You can find over 3000 free medical images here: smart.servier.com/
    Videos were derived from videvo.net, mixkit.co and videezy.com
    Blinking stockfootage, Female Doctor Writing , Email Notification , Female Doctor, Gmail Inbox Button, Antibody, Stethoscope , Scrolling Text, CC-BY 3.0, by videvo.net
    Infected Cells by Beachfront CC-BY 3.0, videvo.net
    Music:
    All of the music is derived from the RUclips Audio library.
    0:00-00:58 Intro
    00:58-5:41 Revolutionizing Cancer Therapies
    5:41-10:03 Inconsistencies and Weird Data
    10:03-10:56 Brilliant Sponsorship!
    10:56-13:17 How Everyone Found Out
    13:17-15:51 The Aftermath
    About Clemens Steinek:
    CLEMENS STEINEK is a PhD student/youtuber (Sciencerely) who is currently conducting stem cell research in Germany.
    This video was sponsored by Brilliant

Комментарии • 35

  • @Sciencerely
    @Sciencerely  Год назад +10

    To try everything Brilliant has to offer-free-for a full 30 days, visit brilliant.org/Sciencerely. The first 200 of you will get 20% off Brilliant’s annual premium subscription.

  • @tainkirrahe
    @tainkirrahe Год назад +156

    I do not understand how people like this don't think they'll be caught as soon as other scientists try to replicate their falsified results??

    • @carolinedelreal9076
      @carolinedelreal9076 Год назад +14

      Because 98% of research isn’t important enough for anyone to check.

    • @mayaraalves2038
      @mayaraalves2038 Год назад +11

      @@carolinedelreal9076 But the other 2% become a general replication, when doctors and clinic around the world will agree with it because "it have a research..."

    • @evo2542
      @evo2542 Год назад

      Simple. They don't consider if they get caught. They just see what they get if they get away with it. They are narcissistic enough to think they can pull the wool over other people.

    • @Arri7979
      @Arri7979 Год назад +7

      I think the people that do this know they'll eventually get caught, but they do it because it could take years or even decades for them to get caught.
      Research studies take years to replicate, so within that time, they could go on to do other research or develop other projects. Those additional projects can give their name more validity, more weight, and over time get them more recognition in their field. By the time someone publishes a paper that debunks their research, they could just say, "The research was sound for the time and circumstances" or, "I wasn't aware of any false information in my study" (this was said in the video) and they could possibly get away with it because they have other credible sources under their belt to still make them looked esteemed.
      In the video, he got caught quickly because he faked other credentials that could be easily debunked, his Rhodes Scholarship lie, so people started digging into his past more and found more inconsistencies.

    • @SmileyxKyley
      @SmileyxKyley 5 месяцев назад

      I think people are replicating studies less frequently nowadays, because replications don’t get published anymore. Replicating a study used to be seen as respectable and important work (as it should be). Now it’s seen as “not good enough” for publication.

  • @MultiSciGeek
    @MultiSciGeek Год назад +49

    There's something so weird about scientists being dishonest. Even worse is them not catching people that are dishonest, when all the data and all should be transparent.

  • @sanjaisrao484
    @sanjaisrao484 Год назад +23

    Please upload more medical scams like this, it's so interesting and it's also important to know.
    Thanks

  • @nerd26373
    @nerd26373 Год назад +17

    Deception and lies are fatal weapons against humanity. Somehow the fame really got into his head. He can no longer process everything in a more sensible and logical way, which is a bit unusual for a medical professional like him.

  • @litrim1285
    @litrim1285 8 месяцев назад +2

    I remember learning about this back in middle school. It was for vacation HW from my 6th Grade science teacher.

  • @coolspider295
    @coolspider295 Год назад +12

    The explanation of cross-validation in this video was botched and is inaccurate. You always split your data into training and development splits, even if you aren't using cross-validation. Cross-validation is when you split your data, train a model, evaluate, then repeat the process with different splits. This lets you get results for your entire dataset, not just a small slice.

  • @demonking86420
    @demonking86420 Год назад +17

    "they aimed to develop a tool that can identify--" HOLD UP
    Like some magic box... that you plug your DNA in... to get like-- This sounds like Theranos

    • @BlisaBLisa
      @BlisaBLisa Год назад +2

      idk this one seems more doable? like you could really make this or something similar. if i understood correctly he was basically trying to make a program that would do what human scientists do but better, basically looking at a cancer cell sample (like a human would) and using all the data it has to pick the best treatment for it. theranos couldnt have worked because it was physically impossible, you cant detect a lot of these diseases she claimed it could from just a drop of blood, you need to take more blood for that. and it was mechanically just a mess and dangerous. but this thing kinda just seems like a computer.

    • @demonking86420
      @demonking86420 Год назад +1

      @@BlisaBLisa possibly but it's like comparing the odds of a supernova shockwave destroying the Earth to the odds of a rogue black hole destroying the Earth

    • @BlisaBLisa
      @BlisaBLisa Год назад +1

      @@demonking86420 i have next to no understanding of this tech or medicine or coding lol im basing this assumption off what i understood from the vid. why would it not work?

  • @Eirexeyes
    @Eirexeyes Год назад +12

    What a piece of work. I hope they throw the book at him for this blatant scam. I hope they do go hard on him. My mother died of cancer, so hearing there was a miracle drug I would have loved to hear but then realising that it was all fake would make the pain of mother having cancer even worse. I really do hope they do go hard on him. The maximum penalty he should get...

    • @demonking86420
      @demonking86420 Год назад +5

      I lost aunts, uncles, cousins, nephews to forms of cancer, the notion that something like that can hoodwink someone with a disease that doesn't really have a cure, is bloody scummy at the least

  • @chesthoIe
    @chesthoIe Год назад +25

    If you were born in the 1800s, everyone was talking about finding a cure for fever. I think our quest for a cure for cancer is of a similar ilk.

    • @riverdeep399
      @riverdeep399 Год назад

      I think it's worse than that. Our own environments and diets can contribute towards cancer, so it will never fully be cured.

  • @owouwu2859
    @owouwu2859 Год назад +6

    Theranos : The prequel

  • @haloforgeguy453
    @haloforgeguy453 9 месяцев назад +2

    Is there any evidence that he just did not cross validate correctly? Since how would he expect this to not fail in actual trials? I should read some of the articles myself.

  • @mehrdokhtp
    @mehrdokhtp Год назад +3

    Do a video on Francesca Gino, the Harvard Prof that recently got busted

  • @IHateThisApp626
    @IHateThisApp626 Год назад +1

    Dude can you PLS tell me what songs you used in the last video were? Just the first two 🥺

    • @Sciencerely
      @Sciencerely  Год назад +2

      Hey! The first two songs from the last video are Free Me and Til I Hear'em Say by NEFFEX - both are part of the YT Audio library!

  • @ZERONECODE
    @ZERONECODE Год назад +8

    he's evil

  • @theshillonggirl
    @theshillonggirl Год назад +3

    2006 was year of scam science!

  • @Irfan-pr1lu
    @Irfan-pr1lu Год назад +2

    💘💘💘