How to Not Kill an Extremely Rare Microbe
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- Опубликовано: 22 май 2022
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For an activity that mostly involves sitting and staring, microscopy is a surprisingly high stakes task. On the other side of the lens are drops full of potential, a multitude of worlds to unravel and examine. But they’re also fragile worlds, easy to fracture and lose with just a tiny slip of the hand. The stakes only get higher when you’re dealing with an organism so rare that it’s only been reported a few times since it was first discovered in 1901.
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Please can you do the top monstrosities that can be found under the scope?!
Was curious about that heritage service.. google the page go in.. BOOM! Credit card details or you shall not pass. Like, wtf kinda of scam is that? Isn't this a reputable channel, to be advertising shit like that?
Get this man some yellowstone water.
It's so nice to hear your voice again, Larissa!
I'm a strong fan of your earlier work.
I wasn't actually watching this channel, but I'll definitely tune in more often now :)
Hello,
We really love your show and are Some of your biggest fans. We really wanted to purchase this microscope to support your project and because we have been inspired by the content you create. I have noticed you are out of stock, would you have a recommendation of a comparable microscope we could buy which would give comparable results? We have purchased one to much disappointment and feel as though we have already wasted a few hundred bucks. Any help you could give would be much appreciated.
So happy we did an episode about Dactylochlamys, I love them so much! I can give a little snippet from the genome work. Some scientists believed that Dactylochlamys is not a ciliate but a flagellate, well, we now know that it's a ciliate for sure. And it's quite distant from them all!😉
-James
wow that is so cool! Did the genome assembly go well?
Dactylochlamys Microcosmosii?
I'm amazed that sequencing works with a sample that contains only one individual microbe. I didn't know that was even possible. Thanks for letting us partake in your research and microbe hunting, James!
Keep up the great work, man
That is amazing. When can we expect more updates or even a full video? Are you gonna make the sequences available for public?
Microscopy may be the one field where we actually know of far, far fewer species than probably exist. Insects might be close, but the sheer number and the obscure size of these organisms makes it so that it's only reasonable to imagine the millions of undiscovered species out there!
Sea creatures, too.
@@samiamrg7 I don't think the sea has quite the possible volume of future discoveries as the microbial world does. There is only so much organic matter that makes its way to the bottom, so while there is absolutely a LOT of species we don't know about, it is probably not close to the millions of undiscovered microbe species because the carrying capacity is a bit more limited. They can cover every single surface on earth, and are often simply overlooked because we're not searching for them like we are with animals.
At the rate they evolve, it might not ever be possible to discover all of them since new species are constantly emerging. I think we're going to learn more about our own DNA by studying microbes than we will ever learn from studying mammals or other large organisms. It's like breaking down the source code of life and looking at the simplest functions contained within.
There are many more species of virus
billions
The only team to not only teach about microscopy, but about the rewards of hard work and persistence.
I love how far this channel has come from chill explorations of more or less well known parts of the microcosm all the way to the immense excitement of active cutting edge research in the field
James be paving the way for re-discovering long-lost species.
I thought James was the microbe
@@johnwt7333 Sorry!
It's so rare, it doesn't even have a Wikipedia article. BTW, the name translates as "clammy fingers" LOL
Fish-shaped clammy fingers?
I wonder if these are widespread, but just in very low concentrations. If, hypothetically, every pond had 100 of these it might seem odd that only a handful of sightings have occurred, but looking at a single drop that just happens to contain one of them is like playing the lottery. It's no wonder that so many new microbes are being discovered all the time. There are probably countless undiscovered species we are constantly coming into contact with.
Imagine it like this, you play the lottery again and again for at least 12 hours every day for years and there are only a handful of people participating in the lottery. So you win quite often! I won 36 times over the last 6 months but winning doesn't mean much, in order to collect your winnings you need to have the winning ticket safe and sound, need to do the paperwork, you need people to acknowledge your paperwork, you need a bank, then you need people to get you into the bank! And at some point bureaucracy of winning becomes so burdensome, you realize that you are just happy to play the lottery without collecting your prizes. :D
-James
@@JamsGerms Are you trying to culture them and grow them up or would that just be futile?
@@HesderOleh i also wondered this. Is it really hard to keep them alive/ have babies?
@@JamsGerms Man that sounds like very thankless work but at least it seems that you truly enjoy what you do. Not many people find their true calling in life but watching the livestreams you look like you have😉
need to be able to genetically test a big batch of soup
The working distance of a 63x 1.4 aperture objective is absurdly short. I think it would be cool to have some videos of the process of using a microscope, collecting and processing samples, etc to help non-microscopists get some context of just how delicate this work can be.
I agree. I remember trying and failing to observe pollen grains in my mid 20s, and being excessively proud when I finally managed to focus the lens on a greenfly.
@4:44 “Lopsided eye-of-Sauron” has to be one of my favorite descriptors to date. Thank you Journey peeps
I learned two things today that I didn't expect to.
Microbes can be rare.
Searching for and photographing microorganisms is like birdwatching for rare birds.
You shall not pass.... away!
What? Make a LOTR reference, expect LOTR jokes!
I was looking for something like this 😂
Wow! Congratulations James!!! 20 of these elusive little beggars! That’s huge!
What do we need to do to send samples to you?
I would reach out to him in insta dms!
Diatoms are so so so awesome. When I first learned about them I was mesmerized. Jewels of the Sea.
So not only rare find and a cool video but also potential discovery scored for the team. Great stuff.
I neither know James personally, nor did I have anything to do with this but I'm still feeling plenty proud of him! :)
I just want to say thank you, I started watching you guys a long time ago and found a new hobby and hopefully a career in microbiology, I have even started a RUclips channel thanks to you guys sharing theses amazing videos with the world. I also love James’s new book he is amazing.
As someone who's been following the channel from the start, I find this video extremely inspiring.
I have completely fallen in love with the milky, aqua-green color of the background of all your videos. Is that color chosen or is it just a lucky circumstance of the microscope light?
Its always nice to hear a story where hard work and persistence pays off.
this channel has proven it's self as a gold mine for the microbiology community, time and time again. I studied cell biology as a filler course while getting a machine tech degree. and this stuff makes me wish I had changed majors. thank you for these amazing opportunities you have given me and other microbe lovers. just watching these momentous occasions is amazing! I can only imagine how people with a career in this stuff feel.
Wikipedia doesn't even have an article on Dactylochlamys yet. Who feels like starting one?
The writing for this series is excellent! It really conveys the excitement of capturing a rare, albeit tiny organism.
I might be dumb, but is it at all possible that these aren't different species, but a very easily mutated organism?
only DNA sequencing will tell us that...
Dumb you are not, that is an interesting hypothesis.
It might be possible that microorganisms could have hypervariable regions, like the VDJ recombination of T lymphocytes, but for a wider geno- and phenotype
@@JC-yv1qj you made me experience unpleasant flashbacks of my immunology classes lmao
@@itsnotawarcrimeifyouhadfun4709 I can understand haha, when I had immunology at med school it was gruelingly challenging, but when I took immunology during my master's it honestly felt like cakewalk, because I learned to love the challenge
Scientist: "I don't want to kill this rare microorganism."
Also scientist: * puts it in freezer *
Very nice job, James! Your persistence pays off! And it's always a treat to get a Journey ep narrated by Deboki!
How exciting! It's fascinating to hear the story of discovery and microscopy process that leads to this rare footage.
Thank you you all, such amazing work, very inspirational.
This is so interesting. I can't wait to hear more about the DNA sequencing.
Congratulations to James, and thank you for the persistence required to add an extra little blip to the sum of human knowledge.
Congratulations on the finds!
congratulations to James and team for the discoveries... fascinating stuff
Good stuff. How about a video on fairy flies? Tiny, but maybe too dry for you...
Congratulations James!! You are a highly patient being!!! Could be 2 different species with seasonal morphological changes?
Brilliant job James, proud of you
Thanks for the sharing, your awesome !
Thank you! And thank you James for your recent post on Instagram 💖
Hundreds of hours looking at samples at after samples for something, until it - maybe - pays of with a discovery, yep, someone is doing science here :).
Congrats.
James is a gamer
grinding for months until the thing he wanted appeared...
nice...
although, unlike gamers, this will help science xd
Yes! It really is like grinding! I forget to eat often!
-James
There are games you can play that helps science like "foldit!"
Kudos James!
Thanks for the awesome content!!
This is so exciting, I can’t wait to see what comes up next, thank you James for all your hard work
All the best Jules
This is why I love this channel
You guys are AWESOME!
Enjoyed your video and I gave it a Thumbs Up for the support of your channel
Alhumdulilah congratulations on finding more beautiful microbes. Keep up the great work Xx
This is so amazing!!!! James is going to make an impact on science one day
OOH! we see the cusp of new microbe knowledge!
Very cool that you are sequencing them. For me just looking at them and observing is only half of their story; one must know their place in the Tree of Life, and hopefully read something about their habitat and morphology!
Have you published scientific papers on these microbes? Where can I find them?
Something tells me James is a huge fan of Pokemon. Here's to you eventually "catching them all". Good luck!
To increase the focus length and give the beast more space, all you need to do is to use binoculars to look into the microscope.
This is freaking awesome
Reminds me of a squid in a few ways.
Great episode. Thank you
Very cool. What happens if we mass breed/cross breed Dactylochlamys?
I'd assume their rarity has something to do with them not reproducing as much as other microbes, but I could be wrong.
So cool!
I have discovered a problem with the ending "...If you would like to see more of us, there is a subscribe button nearby..." ...what if I have seen all the videos? some of the multiple times? I want MOAR!
some of them*
What might you find if you could simultaneously monitor and record an entire drop of water on a slide at one time? Like the wide-field telescopes that have been developed for astronomy. What if you could have an AI constantly monitoring lots of drops and reporting on unusual things it sees? What if you could make a new kind of microscope that works like the event horizon telescope, recording light wavefronts at precise times from different locations and processing them to create an ultra-high-resolution image? What if you could do computed tomography to examine the interior of a microorganism?
The next generation of JttM microscopes should have the ability to link up and create a planet-wide Very Large Microscope Array (aka VeLMA)
I actually got a widefield microscope (Leitz Orthoplan, from the 70's) specifically for this reason. The wide field lets you see more of the slide at once. And when I combine it with a low magnification, large aperture, immersion objective I can see a large area of the slide with very high resolution, and still have good detail if I zoom in with a magnification changer so I don't have to disturb the organisms by changing the objective and re-focusing.
Flagella wiping around was cool. Wish we could have seen it at 1000x magnification, good job on singling the microbe out. Rediscovering a lost species of microbes = Nobel Peace Prize worthy? I bet that made other professional microbiologist jelly.
My favorite content!
Perfect! 👏🏻🔥
"Side-eye of Sauron" was right there.
this episode brought to you by Master of Finding Prized Microbes, the epic Jaaaaaames!!!
The Shiny Pokemon in the Microcosmos
Wow ! , Totally Awesome !,
That's really cool
Does the fact that you guys are discovering new species give this channel the right to name them?
Interesting video. Obviously the depth of field is shallow due to the magnification but have you thought about focus stacking to display a more 3D appearing image or video?
let’s goop that muvropes!! i lobe them the small 💚
i hope it live
The side eye of Sauron.
Excellent video. If you don't mind I want to ask how I download the video for my collection of documentaries but with Latin audio, thanks
Go James!!
This is so great, James! I love how your work continues to add to the body of scientific knowledge. I feel very privileged to be a tiny part of your discoveries. Cheers!
congrats to James for these finds
Go James!
Ohhh fuckkk why!??!?!?!? I didn't once see an eye until you said it and now that's all my brain can see 🤣
I hope you can share some of the data that is discovered when the DNA analyses are done!
It's honestly mind boggling that in this day and age we can just... watch a RUclips channel not only observe an exceptionally rare species in HD video, but also just... nonchalantly discover a new species in the genus being studied like "Oh yeah, and look at this new thing we also discovered."
I thought it looked like a hairy pinecone, with a whole drilled in its side.
Nice vid. Good to see you guys stick to pure science in this one.
Yess
I ain't too familiar with Microbiology (hoping to work towards degrees for it though), but you guys should consider studying the chemical makeup of the habitat (specifically the pond where y'all found it), so we could try to give Dactylochlamys a place to live, granting a better chance to study them because they are in a supreme environment.
What is the pink cluster of cells at 9:09?
I see these somewhat often, but can't photograph them well. I just call them "forbidden raspberries."
Maybe you could film two being 'naughty'. Probably not allowed on RUclips. Great video as always.
How they taste?
Yes
The microscopy version of Shiny Hunting
So very theraputic
2:04
Podrían hacer una lista con todos los vídeos traducidos al español nuevos 🙃?
I wonder if the smallest microbe known has adapted to deal with atom fields
I appreciated Deboki's narration. Thanks.
James should have a new organism named after him!
WHO THIS IS? HUH? WHERE HANKER? HUH
Why wouldn't an inverted microscope be optimal for this use? Thanks
huh, didn't know those were rare. Try an old horse trough that's got a ton of algae growing.
Cool.
Haha the little guy literally did just vanish!
Where is Hank :-(
What the hell was that cacophony at the beginning of the video...? Good Lord...