How are you bro ___ if you have ninja web subscription___ so can you send me the PDF illustration of the lec___ because I have no enough money to take subscription
How are you bro ___ if you have ninja web subscription___ so can you send me the PDF illustration of the lec___ because I have no enough money to take subscription
God bless you, i have listened to my professor recorded lectures for hours and tried to read the book and none of them made sense. But you literally explained them in such a short amount of time and with such good details and with nice delivery! I really appreciate your time and effort! Thank you Dr. Ninja
Sir, I just wonder, how much happy you are during lecture , you are truly passionate about teaching....hats off sir, you are truly amazing, love from India 🇮🇳
You saved me! Thank you for this lecture. I’m starting Medical Physiology this September and I needed a reminder of the fundamentals of cell processes and their interactions. Long life to you, Ninja Nerd
I have a test covering this material today. Can't believe you just published the exact video I need to help understand these concepts! Dude, you're a legend! Single handedly getting me through my online Biochem class, no cap. Thank you for providing this for the public!
Love your videos and I just want to tell you that you guys have been a MAJOR help in me getting through med school these past few years, just have one request that could you please upload more pharmacology lectures? They have been extremely helpful in me getting better grades on my exams!
AS a A-level biology student in the uk watching this amazing video. I'm. not joking when I say his videos are the only ones I don't get bored from watching. all the other ones speak in. such a monotone voice and its so boring that I fall asleep while watching but his videos are so engaging omg they are the best.
I don't know if you ever thought of this , but you should be proud of yourself spreading knowledge across the whole globe. You don't have 50 students or 1000 You have hundreds of thousands of students across the globe who are learning from you and many of them will spread this knowledge to others too... It's really fascinating. Never stop man, we're learning so...o much from you and we love you ❤
Hey zach, cannot thank you enough for your videos, they're literally saving our lives! I know its not the right place, but would you consider going back to neurology and make a video about the medial longitudinal fasciculus? Again, keep up the good work! When i finally finish med school and start working, I'll make sure to send part of my wage someday. YOU'RE THE BEST!
i just started my med journey and i gotta say you have amazed me with your great teaching. thank you for keeping this information free 😊 i will be coming back here alot ❤ may god bless you ❤️❤️
This was made so well! thank you so much Ninja Nerd! I wont lie I thoguth at the end the video ended and i started to watch a different video but it was embedded into this video lol.
As a graduate MSN student just beginning pathophysiology, this has been tremendously helpful. I consider myself a visual person, and the visual aids help me comprehend and remember the process of "fluidity". Keep it up.
circuit methods, simulations to characterize membrane in detail obtaining permittivity, charge regulation with time, ion-ion, particle-membrane interactions are published in membrane journals includes journal of membrane science, journal of polymer science part B: polymer physics, other journals name required is also must
About the transverse diffusion, won’t it mess with the phosphatidylcholine-phosphatidylserine orientation between the inner and outer layers of the lipid membrane? Thanks a lot for providing those much informative lectures for free. I can never be thankful enough and I’d support this channel whenever I am able to :)
Membrane Lipids: Phospholipids: Phospholipids form the basic structure of the cell membrane, arranged in a bilayer. The phosphate head is hydrophilic (water-attracting), while the fatty acid tails are hydrophobic (water-repelling). The composition of phospholipids varies between the outer and inner leaflets of the membrane. Cholesterol molecules are embedded within the lipid bilayer, influencing its fluidity and stability. Transport Across the Membrane: Diffusion: Simple diffusion allows small, non-polar molecules to pass through the lipid bilayer. Lateral diffusion refers to the movement of phospholipids within the same membrane layer. Transverse diffusion involves the flip-flopping of phospholipids from one layer to another, facilitated by enzymes like floppase and flippase. Membrane Proteins: Integral Proteins: Integral proteins span the entire lipid bilayer and can act as channels for molecules to pass through. They have strong interactions with the hydrophobic core of the membrane. Peripheral Proteins: Peripheral proteins are found on the surface of the membrane and interact weakly with the lipid bilayer. They are often involved in signaling and cell adhesion processes. Functions: Transport proteins facilitate the movement of molecules across the membrane, either through channels or by actively transporting them. Exocytosis and endocytosis involve the fusion of vesicles with the cell membrane, allowing materials to be released from or taken into the cell. Receptors recognize specific molecules (such as hormones) and initiate cellular responses. Cell adhesion proteins help cells attach to each other and to the extracellular matrix (ECM). Enzymes catalyze chemical reactions at the membrane surface. Gap junctions allow direct communication between neighboring cells. Glycocalyx: Composition: The glycocalyx is a layer of carbohydrate molecules (sugars) attached to proteins and lipids on the cell membrane surface. Functions: It helps regulate cell-cell interactions, including adhesion and recognition by the immune system. The glycocalyx also plays a role in protecting the cell from dehydration and maintaining proper fluid balance. Membrane Lipids: Phospholipids: Phospholipids form the basic structure of the cell membrane, arranged in a bilayer. The phosphate head is hydrophilic (water-attracting), while the fatty acid tails are hydrophobic (water-repelling). The composition of phospholipids varies between the outer and inner leaflets of the membrane. Cholesterol molecules are embedded within the lipid bilayer, influencing its fluidity and stability. Fluidity of the Cell Membrane: Proper membrane fluidity is essential for the functioning of membrane proteins, including receptors, transporters, and enzymes. It allows these proteins to move within the membrane, interact with other molecules, and perform their specific roles. Fluidity also affects cellular processes such as endocytosis, exocytosis, and cell signaling. Transport Across the Membrane: Diffusion: Simple diffusion allows small, non-polar molecules to pass through the lipid bilayer. Lateral diffusion refers to the movement of phospholipids within the same membrane layer. Transverse diffusion involves the flip-flopping of phospholipids from one layer to another, facilitated by enzymes like floppase and flippase. Membrane Proteins: Integral Proteins: Integral proteins span the entire lipid bilayer and can act as channels for molecules to pass through. They have strong interactions with the hydrophobic core of the membrane. Peripheral Proteins: Peripheral proteins are found on the surface of the membrane and interact weakly with the lipid bilayer. They are often involved in signaling and cell adhesion processes. Transport Across the Membrane: Transport proteins facilitate the movement of molecules across the membrane, either through channels or by actively transporting them. Exocytosis and endocytosis involve the fusion of vesicles with the cell membrane, allowing materials to be released from or taken into the cell. Glycocalyx: Composition: The glycocalyx is a layer of carbohydrate molecules (sugars) attached to proteins and lipids on the cell membrane surface. Functions: It helps regulate cell-cell interactions, including adhesion and recognition by the immune system. The glycocalyx also plays a role in protecting the cell from dehydration and maintaining proper fluid balance. Fluidity of the Cell Membrane: The fluidity of the cell membrane refers to its ability to adapt its shape and movements, a property essential for the proper functioning of cells. The fluid nature of the membrane allows for dynamic interactions between its components and facilitates various cellular processes. Factors Influencing Fluidity: Temperature: Temperature plays a critical role in membrane fluidity. At higher temperatures, phospholipid molecules have increased kinetic energy, leading to more rapid movement and greater fluidity. Conversely, lower temperatures result in decreased fluidity as molecular motion slows down. Cholesterol helps maintain membrane fluidity over a range of temperatures by preventing excessive solidification or fluidization. Composition of Lipids: The composition of lipid molecules within the membrane significantly impacts its fluidity. Unsaturated fatty acids contain one or more double bonds, introducing kinks in the fatty acid tails and preventing close packing of lipid molecules. As a result, membranes containing a higher proportion of unsaturated fatty acids tend to be more fluid compared to those rich in saturated fatty acids, which lack double bonds and have straighter tails. Presence of Cholesterol: Cholesterol molecules are interspersed within the lipid bilayer, where they interact with phospholipids and other membrane components. Cholesterol acts as a buffer against extreme changes in membrane fluidity. At moderate temperatures, cholesterol restrains the movement of phospholipids, reducing membrane fluidity. Conversely, at low temperatures, cholesterol prevents the close packing of phospholipids, enhancing membrane fluidity. Cholesterol also contributes to the overall stability and integrity of the membrane structure. Impact of Fluidity: Proper membrane fluidity is crucial for the functioning of integral membrane proteins, such as receptors, transporters, and ion channels. These proteins rely on lateral diffusion within the lipid bilayer to interact with signaling molecules, transport substrates, and conduct ions across the membrane. Membrane fluidity influences cellular processes such as endocytosis, exocytosis, and cell signaling. Changes in fluidity can affect the efficiency of vesicle formation and fusion, as well as the clustering and activation of membrane-bound receptors and signaling molecules. The dynamic nature of membrane fluidity enables cells to respond rapidly to changes in their environment and modulate their membrane properties accordingly. Cells can regulate membrane fluidity by altering the composition of lipids and adjusting the expression and activity of enzymes involved in lipid metabolism. In summary, the cell membrane is a dynamic structure composed of various lipids, proteins, and carbohydrate molecules, each contributing to its stability, fluidity, and functionality. These components work together to regulate the passage of molecules, facilitate cellular communication, and maintain cell integrity.
I speak for all of us med/premed/nursing etc students when I say you are the best at explaining these concepts!
How are you bro ___ if you have ninja web subscription___ so can you send me the PDF illustration of the lec___ because I have no enough money to take subscription
How are you bro ___ if you have ninja web subscription___ so can you send me the PDF illustration of the lec___ because I have no enough money to take subscription
I agree 💯👍
@@queenzht do you have subscription of his website?
@@farhankakar11 sorry, i don't. I watch only his videos.
Why can't our professors teach like this?
God bless you, i have listened to my professor recorded lectures for hours and tried to read the book and none of them made sense. But you literally explained them in such a short amount of time and with such good details and with nice delivery! I really appreciate your time and effort! Thank you Dr. Ninja
Sir, I just wonder, how much happy you are during lecture , you are truly passionate about teaching....hats off sir, you are truly amazing, love from India 🇮🇳
Tomorrow is my cell structure and function end of semester exams. Sir,you have really prepared me through your lectures🎉❤. God bless you abundantly
You saved me! Thank you for this lecture. I’m starting Medical Physiology this September and I needed a reminder of the fundamentals of cell processes and their interactions. Long life to you, Ninja Nerd
I see nobody is speaking for the vet students, so I will. This is amazing, I hope I pass my cellular biology exam. Thank you ❤
I have a test covering this material today. Can't believe you just published the exact video I need to help understand these concepts! Dude, you're a legend! Single handedly getting me through my online Biochem class, no cap. Thank you for providing this for the public!
Great Channel! Zack we please get a Sepsis video please
Can*
Thank you so much!
We are absolutely hoping to do some sepsis lectures!
Me watching this video in 9th grade and still understands everything thing is crazy.Great explanation sir love from India 🇮🇳
zach knows his stuff through and through. natural born teacher, amazing communicator!
Love your videos and I just want to tell you that you guys have been a MAJOR help in me getting through med school these past few years, just have one request that could you please upload more pharmacology lectures? They have been extremely helpful in me getting better grades on my exams!
How are you sir __ sir can you send me PDF of these all lec ___ because I have no enough money to take subscription of ninja web 🙃
Adoro te, ajudas te me na universidade, obrigado ❤
Um grande abraço de Portugal 🇵🇹
AS a A-level biology student in the uk watching this amazing video. I'm. not joking when I say his videos are the only ones I don't get bored from watching. all the other ones speak in. such a monotone voice and its so boring that I fall asleep while watching but his videos are so engaging omg they are the best.
You are doing well sir for mbbs students
Keep it on for us (students)
Love from India 🇮🇳
The best thing bout ur videos is pictorial representation of everything
I don't know if you ever thought of this , but you should be proud of yourself spreading knowledge across the whole globe.
You don't have 50 students or 1000
You have hundreds of thousands of students across the globe who are learning from you and many of them will spread this knowledge to others too...
It's really fascinating.
Never stop man, we're learning so...o much from you and we love you ❤
THANK YOU SO MUCH. I've got my A level biology exam in a few weeks, so this is going to be INSANELY helpful
I have a final exam in cell biology in a few hours and u have truly saved me
you are the best teacher in the world.
You my ninja. Damn good job on the explanation and "practical application" for lack of a better term
Hey zach, cannot thank you enough for your videos, they're literally saving our lives! I know its not the right place, but would you consider going back to neurology and make
a video about the medial longitudinal fasciculus? Again, keep up the good work! When i finally finish med school and start working, I'll make sure to send part of my wage someday. YOU'RE THE BEST!
Wether or not I understand what you have been ranting about for 40 minutes I love your videos, keep up the good work!
History will be kind to you Sir, humanity is proud of you Sir
i just started my med journey and i gotta say you have amazed me with your great teaching. thank you for keeping this information free 😊 i will be coming back here alot ❤ may god bless you ❤️❤️
I am a university student in Egypt, majoring in dentistry. Histology is an easy subject, but it requires memorization. This is a fact.
Same here i'm 1st year student at Ain shams university and i find histology an easy subject but it needs continuous revision
This guy is a miracle and gift from god to us thank you sir
You are the best sir❤️
The anime helped much love from Nigeria 🇳🇬
Yiiiiiipiiii ..... Tomorrow is my ppr ... And I can't search any vedio ..finally .. I found 😘
Wht is ppr ???
Good luck
Absolutely wonderful teaching and explanations. Thank you for your help!
You are best teacher ❤ I really enjoy your lecture kindly upload more and more videos
This was made so well! thank you so much Ninja Nerd! I wont lie I thoguth at the end the video ended and i started to watch a different video but it was embedded into this video lol.
As a graduate MSN student just beginning pathophysiology, this has been tremendously helpful. I consider myself a visual person, and the visual aids help me comprehend and remember the process of "fluidity". Keep it up.
Thank you for this lecture, you made me understand the whole concept ❤
Learning about cell membrane and it's functions was never so easy and addictive 🤩
Genius 🧠🧠🧠 at work again
Much love from Sierra Leone 🇸🇱🇸🇱🇸🇱
You are the best teacher of the world❤
I’m taking biochemistry and I need to review cell membrane! So this should be helpful I hope! Thank you!
You are literally saving my Masters degree ❤❤❤
Superb video as always, thank you to the whole ninja nerd team you guys rule!!!
Thankyou for this lecture,you never fail to deliver the best of the best.
circuit methods, simulations to characterize membrane in detail obtaining permittivity, charge regulation with time, ion-ion, particle-membrane interactions are published in membrane journals includes journal of membrane science, journal of polymer science part B: polymer physics, other journals name required is also must
Thee besttttttttt proffersor everrrrr🙏🙏 luv from India❤️
You're just a genius at delivering information.🌹💗
you make nice videos which includes both animation and teaching
😇😇😇😇😇
i think this guy was made for this work..I mean damn😭😭❤️
you literally saved my life thank you!!
Thanks so much Zach.
This man is made of brainsssssss 👀
Definitely helped me for my assignment 😊
ZACH!!!! I Love you my brother🙏🏻🤍 I’m sending you red roses when I graduate nursing school. Red to represent your passion for teaching 🌹
Amazing Explanation 👏
Thanks very much this is really helpful
You are amazing 🤩
Now I love biochemistry 😅
Very helpful, Special thanks to NinjaNerd
Wao what a teacher he is
Good work Prof...I salute sir... enjoying the lecture from Nairobi Kenya
Thanks so much sir you are the best teacher
Please upload Remaing videos of Pharmacology on antidepressants, antipsychotics and Anesthetics
The best channel ever! I keep sharing ninja nerd with all of my friends! 🥹🥹🥹🥹
Thank you so much. This Video explained what I’m learning this week, wish me luck!🙏🏼
🎉the best and simple to understand❤
Perfect explanation
I mean the best teacher that existed
His Passion is unmeasurable
About the transverse diffusion, won’t it mess with the phosphatidylcholine-phosphatidylserine orientation between the inner and outer layers of the lipid membrane?
Thanks a lot for providing those much informative lectures for free. I can never be thankful enough and I’d support this channel whenever I am able to :)
Subscribing right noww!
The awaited finally out🔥🔥
Helpful thankyou so much buddy ❤
Thanks ninjanerd...it help a lot...
This is the very embodiment of the Feynman Technique 👍
You are the best ninja nerd 🎉🎉🎉
Membrane Lipids:
Phospholipids:
Phospholipids form the basic structure of the cell membrane, arranged in a bilayer.
The phosphate head is hydrophilic (water-attracting), while the fatty acid tails are hydrophobic (water-repelling).
The composition of phospholipids varies between the outer and inner leaflets of the membrane.
Cholesterol molecules are embedded within the lipid bilayer, influencing its fluidity and stability.
Transport Across the Membrane:
Diffusion:
Simple diffusion allows small, non-polar molecules to pass through the lipid bilayer.
Lateral diffusion refers to the movement of phospholipids within the same membrane layer.
Transverse diffusion involves the flip-flopping of phospholipids from one layer to another, facilitated by enzymes like floppase and flippase.
Membrane Proteins:
Integral Proteins:
Integral proteins span the entire lipid bilayer and can act as channels for molecules to pass through.
They have strong interactions with the hydrophobic core of the membrane.
Peripheral Proteins:
Peripheral proteins are found on the surface of the membrane and interact weakly with the lipid bilayer.
They are often involved in signaling and cell adhesion processes.
Functions:
Transport proteins facilitate the movement of molecules across the membrane, either through channels or by actively transporting them.
Exocytosis and endocytosis involve the fusion of vesicles with the cell membrane, allowing materials to be released from or taken into the cell.
Receptors recognize specific molecules (such as hormones) and initiate cellular responses.
Cell adhesion proteins help cells attach to each other and to the extracellular matrix (ECM).
Enzymes catalyze chemical reactions at the membrane surface.
Gap junctions allow direct communication between neighboring cells.
Glycocalyx:
Composition:
The glycocalyx is a layer of carbohydrate molecules (sugars) attached to proteins and lipids on the cell membrane surface.
Functions:
It helps regulate cell-cell interactions, including adhesion and recognition by the immune system.
The glycocalyx also plays a role in protecting the cell from dehydration and maintaining proper fluid balance.
Membrane Lipids:
Phospholipids:
Phospholipids form the basic structure of the cell membrane, arranged in a bilayer.
The phosphate head is hydrophilic (water-attracting), while the fatty acid tails are hydrophobic (water-repelling).
The composition of phospholipids varies between the outer and inner leaflets of the membrane.
Cholesterol molecules are embedded within the lipid bilayer, influencing its fluidity and stability.
Fluidity of the Cell Membrane:
Proper membrane fluidity is essential for the functioning of membrane proteins, including receptors, transporters, and enzymes.
It allows these proteins to move within the membrane, interact with other molecules, and perform their specific roles.
Fluidity also affects cellular processes such as endocytosis, exocytosis, and cell signaling.
Transport Across the Membrane:
Diffusion:
Simple diffusion allows small, non-polar molecules to pass through the lipid bilayer.
Lateral diffusion refers to the movement of phospholipids within the same membrane layer.
Transverse diffusion involves the flip-flopping of phospholipids from one layer to another, facilitated by enzymes like floppase and flippase.
Membrane Proteins:
Integral Proteins:
Integral proteins span the entire lipid bilayer and can act as channels for molecules to pass through.
They have strong interactions with the hydrophobic core of the membrane.
Peripheral Proteins:
Peripheral proteins are found on the surface of the membrane and interact weakly with the lipid bilayer.
They are often involved in signaling and cell adhesion processes.
Transport Across the Membrane:
Transport proteins facilitate the movement of molecules across the membrane, either through channels or by actively transporting them.
Exocytosis and endocytosis involve the fusion of vesicles with the cell membrane, allowing materials to be released from or taken into the cell.
Glycocalyx:
Composition:
The glycocalyx is a layer of carbohydrate molecules (sugars) attached to proteins and lipids on the cell membrane surface.
Functions:
It helps regulate cell-cell interactions, including adhesion and recognition by the immune system.
The glycocalyx also plays a role in protecting the cell from dehydration and maintaining proper fluid balance.
Fluidity of the Cell Membrane:
The fluidity of the cell membrane refers to its ability to adapt its shape and movements, a property essential for the proper functioning of cells. The fluid nature of the membrane allows for dynamic interactions between its components and facilitates various cellular processes.
Factors Influencing Fluidity:
Temperature: Temperature plays a critical role in membrane fluidity. At higher temperatures, phospholipid molecules have increased kinetic energy, leading to more rapid movement and greater fluidity. Conversely, lower temperatures result in decreased fluidity as molecular motion slows down. Cholesterol helps maintain membrane fluidity over a range of temperatures by preventing excessive solidification or fluidization.
Composition of Lipids: The composition of lipid molecules within the membrane significantly impacts its fluidity. Unsaturated fatty acids contain one or more double bonds, introducing kinks in the fatty acid tails and preventing close packing of lipid molecules. As a result, membranes containing a higher proportion of unsaturated fatty acids tend to be more fluid compared to those rich in saturated fatty acids, which lack double bonds and have straighter tails.
Presence of Cholesterol: Cholesterol molecules are interspersed within the lipid bilayer, where they interact with phospholipids and other membrane components. Cholesterol acts as a buffer against extreme changes in membrane fluidity. At moderate temperatures, cholesterol restrains the movement of phospholipids, reducing membrane fluidity. Conversely, at low temperatures, cholesterol prevents the close packing of phospholipids, enhancing membrane fluidity. Cholesterol also contributes to the overall stability and integrity of the membrane structure.
Impact of Fluidity:
Proper membrane fluidity is crucial for the functioning of integral membrane proteins, such as receptors, transporters, and ion channels. These proteins rely on lateral diffusion within the lipid bilayer to interact with signaling molecules, transport substrates, and conduct ions across the membrane.
Membrane fluidity influences cellular processes such as endocytosis, exocytosis, and cell signaling. Changes in fluidity can affect the efficiency of vesicle formation and fusion, as well as the clustering and activation of membrane-bound receptors and signaling molecules.
The dynamic nature of membrane fluidity enables cells to respond rapidly to changes in their environment and modulate their membrane properties accordingly. Cells can regulate membrane fluidity by altering the composition of lipids and adjusting the expression and activity of enzymes involved in lipid metabolism.
In summary, the cell membrane is a dynamic structure composed of various lipids, proteins, and carbohydrate molecules, each contributing to its stability, fluidity, and functionality. These components work together to regulate the passage of molecules, facilitate cellular communication, and maintain cell integrity.
this is now my go-to for cramming before a bio test
Awesome video ❤
I’m passing my class because of you !
No.. You are passing your class because of YOUR hard work! Congratulations! - TG
Can any one explain the mechanism how glycocalyx help in water control
Kindly make video for entire cell biology please.
Please more cell biology.
Very much clear and understandable 👌 😊😊
I enjoyed your lecture, thank you😂
AMAZING VIDEO!!!!!!!!!!!!!!!!!!
The lecture was extremely helpful like extremely ,Thankyou very much!!!!!
back to the basics💪💪
Extremely helpful lecture. Excellent
Thank you, NINJA!!
Big up man 💯🙏🏾
Thank you so much ❤
Thanks for great information
Neja nerd since we need pharmacology series please
Such an intelligent man.
Seriously. Thank you!!!!
I love this channel
I wish more teacher teach like this for these types of subjects rather then read off thier long worded slides.
Great sir g very very conceptual
Finally I found my teacher
Your videos are superb. Tq a hundred times over.
Really amazed by explanation ,keep it up sir for us, thank you so much
Love from INDIA
Great job ❤❤❤❤
Excellent! Thank you!