Haemochromatosis (Iron Overload) - iron physiology, causes and pathophysiology

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  • Опубликовано: 1 янв 2025

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  • @armandohasudungan
    @armandohasudungan  Месяц назад

    🎥 DON'T JUST WATCH, LEARN ACTIVELY! TRY THE QUIZ! 🤓
    youmakr.ai/test-playground/questionnaire/673d329e859b9c170836ea32

  • @growthzack9542
    @growthzack9542 2 года назад +40

    I’ve seen countless doctors about my symptoms (internal tremors, trouble breathing upon falling asleep, chest pains, poor circulation, etc). They all attributed it to anxiety. I finally saw a holistic doctor and be immediately said it’s iron overload. Getting blood work done this week. Let’s see what happens. I need relief

    • @Zerturnosrs
      @Zerturnosrs Год назад +4

      Hey man are you still going through this? I just got high iron on a blood test and Ive lost 17kgs in in a few months. Was told it was anxiety too

    • @growthzack9542
      @growthzack9542 Год назад +3

      @@Zerturnosrs Yes, but it doesn’t seem to be iron overload. My tests came back normal, including iron levels. The investigation continues. I have been using some new strategies that seem to be improving things for me (getting my dopamine baseline back to normal, no eating 3 hours before bed, etc). Considering that your levels are high, you should fight to rule out every possibility. It might be iron overload - most American doctors aren’t even familiar with the condition. Get as many 2nd opinions as needed for you to be 1000% sure

    • @Skybluewindcool
      @Skybluewindcool Год назад

      @@growthzack9542 Do u have iron overload ? Your Hemoglobin level is ?

    • @howardmann8689
      @howardmann8689 Год назад +2

      My ferratin has dropped from 4100 to 2300 after 3 blood draws in 4 months

    • @Skybluewindcool
      @Skybluewindcool Год назад

      @@howardmann8689 What are your symptomps ?

  • @jenniferkempa4148
    @jenniferkempa4148 3 года назад +14

    It's amazing that you did a video explaining this. So few people have heard of it in the United States - even family physicians. It runs in my family quite extensively.

    • @medlecture4838
      @medlecture4838 3 года назад

      ruclips.net/channel/UCMm0dSPawfVKMsQuEpcwvPA

  • @jesusandmedicine1950
    @jesusandmedicine1950 3 года назад +20

    Thanks for sharing this lecture. It was helpful and informative. God bless you

    • @medlecture4838
      @medlecture4838 3 года назад

      ruclips.net/channel/UCMm0dSPawfVKMsQuEpcwvPA

  • @joemama-tn7zl
    @joemama-tn7zl Год назад +4

    By far the best explanation on you tube

  • @leahmhoward
    @leahmhoward 3 года назад +12

    Thank you for this. This disease runs in my family and even as a paramedic so little is known about it.

    • @EllaBella-76
      @EllaBella-76 3 месяца назад

      @leahmhoward •Apparently it's called the Celtic Curse lots of cases in Scotland? Why I have no idea 🤷‍♀️

  • @szintivideo2984
    @szintivideo2984 Год назад +8

    The black tea is effective against high blood iron level. For me helped a lot, and made me healthy again.

    • @marypolk9820
      @marypolk9820 Год назад

      Is that regular tea or a black tea????? I have high iron. I don't think I can give blood though. I do take liquid vitamin C.....

    • @szintivideo2984
      @szintivideo2984 Год назад

      Black tea ! Only black tea, nothing more! I using high dose multivitamin without iron. The zinc and copper helps reduce the iron level too. I using them too, in my multivitamin complex.@@marypolk9820

    • @vonnanolan7811
      @vonnanolan7811 11 месяцев назад

      Zero data to support this

    • @szintivideo2984
      @szintivideo2984 11 месяцев назад

      Then try it !
      @@vonnanolan7811

    • @MrAbi123
      @MrAbi123 10 месяцев назад +1

      That’s because of oxalate dumping also don’t eat enriched/fortified foods if your iron is high

  • @hothanabdi625
    @hothanabdi625 Год назад +3

    Thank you from Kenya 🇰🇪

  • @hicoteo
    @hicoteo 2 года назад +6

    My step dad developed iron overload as he aged. For other reasons he went on a keto diet for four months, lost 40 pounds, then continued to eat healthy. His iron problem went away.

  • @sarahc.167
    @sarahc.167 3 года назад +7

    Thank you so much. This is exactly the video I needed! Great graphics and explanation

    • @medlecture4838
      @medlecture4838 3 года назад

      ruclips.net/channel/UCMm0dSPawfVKMsQuEpcwvPA

  • @elcancerynosotros.7036
    @elcancerynosotros.7036 6 месяцев назад +2

    Wow! Amazing synthesis of this patology. Thanks!

  • @salvadormercado3731
    @salvadormercado3731 Год назад +3

    UN VIDEO INCREIBLE!!!
    MUCHAS GRACIAS MASTER

  • @donovanlucibello379
    @donovanlucibello379 2 года назад +3

    Stellar video, very concise and clear. Cheers!

  • @brianfoley4328
    @brianfoley4328 3 года назад +2

    Just outstanding....great presentation...Thank You

  • @aloevera1269
    @aloevera1269 3 года назад +3

    God bless you for your work!!!

  • @mabrouk642
    @mabrouk642 13 дней назад

    What a thourough explanation, Thank you!

  • @1aliveandwell
    @1aliveandwell Год назад +1

    Interesting. Did check 23andme results and all neg for this. Checked as 3x's in last 2 yrs had slightly high iron, but ferritin ~34,45.. Confusing, but have read on B12 that have high labs may not be correct as antibodies can interferre with some analyzers. Need B12 (which needs B2(Se,I) to use iron, so many connections !

  • @nicealloys
    @nicealloys 9 месяцев назад

    I have just been diagnosed and have several side effects I'm just trying to understand it all thanks for the video ❤

  • @andora9695
    @andora9695 3 года назад +4

    Your work is absolutely insane ! Thank you so much :)

  • @lienbich6557
    @lienbich6557 2 года назад

    thanks for ur video, it makes me get clearly about the hemochromatosis mechanism, hope u upload more videos about the other system, from vietnamese with luv

  • @angelinawilliamson6841
    @angelinawilliamson6841 Год назад +1

    Great explanation thank u

  • @ivetamosesyan4621
    @ivetamosesyan4621 3 года назад +2

    You are the best. Thanks a lot👏👏👏

  • @raadshakerabbas
    @raadshakerabbas 3 года назад +7

    Thank u from Iraq 🇮🇶❤🥀

  • @samuraimaster99
    @samuraimaster99 Год назад

    best video I have seen on this topic. thanks!

  • @ok-kb7yz
    @ok-kb7yz 3 года назад +3

    Armando.....the link to purchase PDF has broken. Hope you'll fix it soon. I have to purchase some PDFs soon for my exams.

    • @armandohasudungan
      @armandohasudungan  3 года назад

      hmmm not sure, Check now?

    • @ok-kb7yz
      @ok-kb7yz 3 года назад

      @@armandohasudungan now ita opening but when i click add to cart option this happens. armandoh . org
      500 Internal Server Error
      An error has occurred while handling your request. The most common reasons for this are:
      A malfunctioning script or CGI application.
      An invalid or inaccessible .htaccess file.
      Please contact the site administrator for assistance.
      If you are the site administrator:
      Enable and check your site's error log for more information.
      Check to make sure CGI scripts are set properly executable.
      Make sure CGI scripts are uploaded in Unix text file format (newline-only).

    • @ok-kb7yz
      @ok-kb7yz 3 года назад

      @@armandohasudungan pls fix it. My exams are Scheduled next month...... I have to revise everything within 25 days.

    • @CEJM100
      @CEJM100 3 года назад

      It's still down 🥺 I'm hoping to purchase some pdfs as soon as it's back up

    • @ok-kb7yz
      @ok-kb7yz 3 года назад

      @@CEJM100 i know, but what can we do.......... Armando, pls fix it buddy.

  • @RobertBrown876
    @RobertBrown876 11 месяцев назад

    I just saw a correlation on another RUclips video that over time as your body takes out more iron. It just accumulates in the body and thus overall you have a shorter lifespan
    How do you...
    A. Remove iron that has gotten into the organs.
    That has accumulated acutely over the past 20-30 years
    B
    How do you minimize the effects of the biochemical reaction of the oxidative reaction that takes place once inside your cells?
    c.
    How do you reverse the damage from the oxidative reaction in the organs? (This is assuming small accumulative iron over the 20 years, this is not signifying any disease amok to any point)

  • @prosperitypeace1554
    @prosperitypeace1554 3 года назад +2

    Thank you 🙏

  • @vipse1984
    @vipse1984 Год назад +1

    Just started getting diagnosed for this...getting nervous

  • @abdulmajidmuhammad15
    @abdulmajidmuhammad15 3 года назад +1

    Your videos are very helpful really!!
    Thanks for the effort and all
    But can you please do a video on the pharmacology of Anti-biotics and anti-fungal?
    It'd really help

  • @erfanlatoon1050
    @erfanlatoon1050 3 года назад +1

    Thank you teacher

  • @MichaTheLight
    @MichaTheLight 2 месяца назад

    4:40 If you eat 2 pounds of red meat a day with vitamin C you could arrive at such high levels. Meat alone isn't the reason when you eat red meat with Orange Juice and that on a daily you would really have a problem. Same if you take multivitamin to your high red meat meals.

  • @Jack-uy7ie
    @Jack-uy7ie 3 года назад +1

    What about the benefits of the mutation?

  • @bulutewr3314
    @bulutewr3314 3 года назад +1

    That's amazing, thank you so much

  • @shivasaipraneethbethi8150
    @shivasaipraneethbethi8150 9 месяцев назад

    Good explanation

  • @TheRustyLM
    @TheRustyLM 3 года назад +1

    That was great! Thank you!

  • @Mickymouse-lx8eb
    @Mickymouse-lx8eb 2 года назад +1

    Very very interesting 🤨

  • @Sundasfashion
    @Sundasfashion 3 года назад +1

    please one vedio for THORACIC VERTEBRA i am your student and i need your help in thoracic vertebra topic please

  • @XxxPYTHON
    @XxxPYTHON Год назад

    How iron toxicity reduce by medicines, how they work please explain

  • @elcancerynosotros.7036
    @elcancerynosotros.7036 6 месяцев назад

    Outstanding!

  • @Clinical1114
    @Clinical1114 3 года назад +2

    Thanku sir ❤️❤️ .

  • @الخلاصهفيحكايه-ض3ه
    @الخلاصهفيحكايه-ض3ه 3 года назад

    Please discuss ditals about analysis chimestry body flouds.. As blood chimestry.. Liver function.. Kidney function..... Urin.. Stool.. Spotum

  • @adsaad
    @adsaad 2 года назад +1

    My current iron level in my blood is 165. (The normal range is 45 - 145) ug/dl. Is my level alarming? Thanks for your attention and for your videos.

  • @theaprecup
    @theaprecup 9 месяцев назад

    Hi, I am curious why iron would be high but ferritin would be normal.

  • @فاطمةمحمد-ت5ت
    @فاطمةمحمد-ت5ت 3 года назад +1

    Thank u 💙

  • @laurenhanlon
    @laurenhanlon 10 месяцев назад

    My ferritin is 46 but my haemoglobin is really high? I need to raise my iron but I don’t want to raise my haemoglobin too much? What can I do?

  • @sierrabravo7368
    @sierrabravo7368 5 месяцев назад

    I just watched the Haemacromatosis episode of House MD

  • @ArabMiracles
    @ArabMiracles 3 года назад +1

    very informative, THANKS

  • @moonbunny7380
    @moonbunny7380 2 года назад +1

    does anyone know why I have too much iron my doctor thinks I have this even though I haven't ate red meat in years and she also said i have low folic acid but not anemia?? I thought i had it because I dont eat red meat

    • @MrAbi123
      @MrAbi123 10 месяцев назад +2

      Avoid fortified/enriched foods and have a look into oxalate dumping/toxicity

  • @nicejoy9998
    @nicejoy9998 Год назад

    My ferritin is 133, transferring saturation 51% blood iron 185 is it normal? My liver enzymes are normal.

    • @MrAbi123
      @MrAbi123 10 месяцев назад +1

      Is your iron is high avoid fortified/enriched foods

  • @bh9262
    @bh9262 Год назад

    How do you lower iron in the body?

    • @MrAbi123
      @MrAbi123 10 месяцев назад +1

      Avoid enriched/fortified foods

    • @MarykayOsoski
      @MarykayOsoski 2 месяца назад

      Give blood, donate at blood bank

  • @PythagorasHyperborea
    @PythagorasHyperborea 3 года назад

    What about leaky gut syndrome as a cause? That’s another common issue.

  • @user-pj9ce5lb9q
    @user-pj9ce5lb9q 2 года назад +1

    just a question, I got a bit lost when you said Hepcidin is released when iron storage is overloading which inhibits ferroportin. But if ferroportin is inhibited, does that mean iron will continue to build up in storage as ferritin instead of being released even though storage levels are high? Might be a silly question but I'm just a bit lost. Can someone please explain

    • @johnherrington1110
      @johnherrington1110 Год назад +1

      Your question is several months old, so forgive me if you have already figured this out… You have ferroportin exactly backwards. If ferroportin is active, it is bringing in new iron from the diet. If it is inhibited by hepcidin, this will slow or stop absorption of new iron from the diet, thereby dropping iron concentration in blood serum and eventual uptake by the liver. With no new iron coming in, stores will be used to make new RBC’s, drawing down overall supply and less production of hepcidin allowing a new iron to be absorbed from the diet, and the cycle repeats.

    • @user-pj9ce5lb9q
      @user-pj9ce5lb9q Год назад

      @@johnherrington1110 thanks. I wish I knew this before my exam 😂 figured it out the second time

  • @fbluejay4194
    @fbluejay4194 3 года назад +1

    I hoped you'd mentioned the induced effect of inulin on hepcidin (therefor insulin resistance and predibetics are high risk)

  • @dionnelong
    @dionnelong 10 дней назад

    I can’t believe how full and empty all these iron videos are. How much is enough? How much is too much?

  • @daffaho4921
    @daffaho4921 3 года назад

    Pathophysiology means study of altered physiology of host for all neet aspirant 2021 💥💣💥💣💥💣💥💣

  • @Ghaidahrb
    @Ghaidahrb Год назад +1

    1:55 I heard baby crying 😢

  • @KosspapiKaufman
    @KosspapiKaufman 3 года назад

    I think I saw something like this while passing through renal calculi Today

  • @einsteinbrother2905
    @einsteinbrother2905 2 года назад

    Plz put it

  • @유진김-t1r
    @유진김-t1r Год назад

    [21158] kim It was good because they explained it easily in a picture.

  • @Brim_the_Wizard
    @Brim_the_Wizard 3 года назад

    Tiamat bless

  • @qamirnamroudi5802
    @qamirnamroudi5802 3 года назад

    Top ..

  • @einsteinbrother2905
    @einsteinbrother2905 2 года назад +1

    I want seizures explain

  • @docontherange
    @docontherange 2 месяца назад

    Heck yeah, bloodletting

  • @dilawarrana5999
    @dilawarrana5999 Год назад

    😢

  • @SheereenKhan-r1r
    @SheereenKhan-r1r Месяц назад

    😍😍

  • @sanjinaershad1609
    @sanjinaershad1609 Год назад

    A.I said - all doctors are fool.

  • @sullypwz7864
    @sullypwz7864 2 года назад

    this video dont answer why iron overload is harmful, btw very bad letters