1) Adeno Associated Virus (AAV) - An Introduction
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- Опубликовано: 10 сен 2024
- Adeno Associated Virus (AAV) is a new gene delivery system that is ideal for gene therapy. They are small and relatively simple viruses that have broad host range, and their apparent lack of pathogenicity and low immunogenicity increase their potential as viruses for gene therapy.
Adeno-associated viruses offer numerous advantages over Lentivirus and Adenovirus gene delivery systems. The numerous AAV serotypes allow viral infection in virtually all tissue types, and its ability to infect both the dividing and quiescent cells makes them a great gene delivery tool for genome editing applications, such as CRISPR-Cas9 knock out. In this video, we will introduce some key features of adeno-associated viruses and briefly and go over its pros and cons as a genome editing tool.
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