PliaFX® Pak Packable Demineralized Fibers and Chips

PliaFX Pak is 100% bone. It is a proprietary mix of mineralized bone chips with moldable demineralized fibers that provides optimized handling, hemostatic1 and osteoconductive1,2,3† properties. The precision-machined fibers interlock with the bone chips, allowing the graft to become moldable upon rehydration without the use of a carrier.1,3,4†
PliaFX Pak can be used in orthopedic fractures, fusions, osteotomies and other procedures that require filling an osseous defect. Clinical applications may include lumbar interbody fusion, cervical laminoplasty, anterior cervical discectomy and fusion (ACDF), opening wedge high tibial osteotomy (HTO), distal femur fracture, calcaneal fracture, and proximal humerus fracture.
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1.LifeNet Health, PliaFX® Pak - Moldable Demineralized Fibers White Paper.2022. 68-20-369.00.
2. Murphy MB, Suzuki RK, Sand TT, et al. Short term culture of mesenchymal stem cells with commercial osteoconductive carriers provides unique insights into biocompatibility. J Clin. Med. 2013; 2,49-66; doi:10.3390/jcm2030049
3. J. B. McLean, N. Carter, P. Sohoni, and M. A. Moore, ‘Cell Attachment and Osteoinductive Properties of Tissue Engineered, Demineralized Bone Fibers for Bone Void Filling Applications’, Clinical Implementation of Bone Regeneration and Maintenance. Intech Open, Feb. 10, 2021.
4.Brydone AS, Meek D, Maclaine S. Bone grafting, orthopaedic biomaterials, and the clinical need for bone engineering. Proc Inst Mech Eng H. 2010;224(12):1329-1343.
† Pre-clinical test data/results may not necessarily be indicative of human clinical performance (or outcomes).