Toll like receptors

[@GhandourMD]

Great videos , but i think that TLR-4 is for LPS not TLR-3.TLR-3 is in the inner surface membrane of Endosomes.

[@shomusbiologyofficial]

Yes you are right.

[@neetladder]

Further TLR 3 binds with the viral dsRNA.

[@m.bosman25]

Thanks a lot but I think there is no voice after 6:44 , am I right?

[@fizarafique8150]

Your voice is not heard to me in PAMPS portion.otherwise your video is great.

[@asmaaaaliasmaaalani6665]

Thanks from Iraqi student
Nice

[@shomusbiologyofficial]

You're welcome

[@azeemnaeem6720]

I get very benifit from your lectures. Thank you sir g and best of luck.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@avinashreddyAvinashreddy717]

sir we are having really hard time dealing with genetics...can you please make video telling everything about genetis that a medical student is supposed to know...we would be greatful if so

[@muniralm.j.7140]

Hi doctor, hope u r doing well, i just wanted to remind you these days :) your comment was like 5 years ago, are u graduated now ?

[@avinashreddyAvinashreddy717]

@@muniralm.j.7140 yes sir I have graduated and working currently

[@chankyaangra2302]

Please add sound in last part of the video...

[@monzurmorshed.]

Thank you for your video Shomu da. I have one comment. In this video, it seems like you are suggesting TLR can not detect ds RNA, ssRNA and CpG DNA. But actually, it can detect nucleic acids and some TLR detect this in an endosome. It would be better if you could somehow add these details or maybe make a new video about it.
I always look forward to your videos. You are doing a great job!

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@ramchandrasuthar2848]

exactly TLR 4 for LPS
TLR 3 for inner membrane of endosome

[@Lovefornature555]

Sir does Toll like receptors play an important role in immune defence by recognising microbial components??

[@sagniksadhukhan]

Yes of course.

[@adriant.4215]

Its so fun to watch it at Speed 1.75 :)

[@shwetadongre4847]

Please make this video again ,there is some problem in the end of the video

[@shomusbiologyofficial]

Okay. What's the problem?

[@shwetadongre4847]

@@shomusbiologyofficial from 5:14 video same as in the starting n the audio is in continuation,n then video is also not audible,so it's hard to understand,

[@pranjalipatil9574]

Sir this video does not sound properly

[@jaserahsyed441]

Sir lps is a ligand for TLR 4

[@dibyajyotirmayeebehera481]

Very well explained sir🙏🏻👌🏻

[@sudarshandongare4001]

Plz make Videos on Leishmania and Leishmaniasis :-) ...

[@DA-sj2gw]

Which molecule(s) is/are NOT normally induced by TLR signaling (TLR=Toll‐Like Receptor)?
A. TNF‐alpha
B. IL‐1
C. iNOS
D. IL‐6
E. IL‐4

[@world1923]

Why they are named as toll?? Sir..

[@malaikasubhani4341]

Its bcz scientists were so surprised after finding out some mutations happened in fruit fly which makes its embryo look unusual.. due to these receptors. So they surprisingly shouted in German " Das ist ja toll" which means "that's great". Origin of the word toll

[@pragyachaudhary4704]

sir plz MyD88 independent and dependent pathway par bhi lecture deven

[@shomusbiologyofficial]

Okay

[@sangeetamuglikar5066]

No audio from 6.3

[@shomusbiologyofficial]

Use both headphones

[@jamalsayed8828]

Sir there isn't voice in this lecture

[@shomusbiologyofficial]

And all these people hear it. How?

[@jamalsayed8828]

Chk all comments Sir many having audio issued

[@pranjalipatil9574]

On toll like receptor and pmps

[@sukinaikab3993]

UR THE BEST..

[@shomusbiologyofficial]

Thank you

[@kaydee5639]

no sound in 2nd half

[@shomusbiologyofficial]

Use both headphones

[@danialtaghipour8280]

video needs edition

[@sriram97]

TLR - This Little Rapper explains about Toll-like Receptors

[@ramchandrasuthar2848]

shruthi
it may be tecnical problem

[@swetapadma325]

It is TL4

[@sharvaridevkar1247]

Sir is any role of TLR on ribosome who infected by RNA virus

[@ramchandrasuthar2848]

I dont know
but it should be solve

[@ramchandrasuthar2848]

There is NO VOICE
in this video
Silent video
Check it please

[@sruthyg2525]

+Ramchandra Suthar u r crrct ...why its so

[@priyaw5120]

Im facing the same issue

[@Lifjunction]

Then why not Tcr(T cell receptor) called toll like receptor

[@AntiSVH]

Ritika Singh Because TCR bind to the MHC with the epitope, and not a PAMP

[@sahanask975]