seems to be confusing to me, the more I watch. Eat more protein eat less protein, eat 30 grams of protein twice a day but eat 1 gram of protein per pound, but anything over 45 grams of protein is a waste but maybe the liver will use it. Really does anyone really know?
My dads 93 my mum is 90, they still live at home and are very fit and look after themselves and others, they have never listened a health podcast, read a health book other than articles in Readers Digest. They eat and drink what they want both have carried a little extra weight though they deny it. They drink alcohol moderately. They have never fussed about their diet but do avoid sugar and hidden sugars. They have been physically active but never went to a gym, sauna, steam room or spa or lifted weight. They rode bicycles up till their 80’s. Compared to today their early life was austere with just enough food. I hope I’ve got some of what they have.
@@DrGabrielleLyon 😅 Just honestly never thought I’d see any contemplation of protein restricting on your channel, but it’s good to keep an open mind and explore ideas that may run counter to our own 🧠
Great interview! Yes!! Please do a peri-post menopausal podcast with Dr Tracy Anthony on nutrition, muscle/bone retention, and protein needs for optimal health as we age. Thank you!
Another great video by one of my favorite Dr's! Thank you, Dr. Lyon! My favorite part about all of these videos by my favorite dr's are that they interview to ask questions and try to keep learning, whether they already know what they're talking about or not. None of them act like they're the last word on anything that they talk or ask about. Very refreshing! No egos doing battle. The modesty and humbleness of these super smart dr's is another favorite part of these videos. Thank you two great dr's for this video!
Why is literally mentioning their gender a problem? Your are the kind of guy who will shit on women's accomplishment and have no problem when men are mentioned instread. Stating they are women is NOT a sexist move @@littleyummy1517
Love listening to you two talk in your science lingo. As if its a foreign language which it is to most people. My Bachelor of science was in food science technology and nutrition so it cracks me up when you two are talking like this. Great and informative, I’m eating it up, zero calories.
off topic but science is the main reason i believe in a creator , humans and other organisms and the workings of our bodies and how we interact with our environments is to complex to have happened by chance. a supremely intelligent being must have created us.
I never heard her say what her macronutrient breakdown that she eats? She said no diet is a bad diet! Intermittent fasting and two meals a day! So how much freakin protein is appropriate? That is why everyone is watching this video so we are not hurting ourselves with all this protein!
Important and helpful interview. Some of the comments are not acknowledging the nuance in developing the diet. Other commenters get it, though, when they say that a fast, then feed approach may be optimal because it accomplishes both restriction (fasting) and repletion (feeding). Thanks, Dr. Lyon, for posting this.
This is taking me back to my university days. The hated days of microfiche and card catelogues. Those days sucked in some ways but getting lost in the campus library reading journals and microfiche.
Would love to see studies done on post menopausal women raised on the SAD diet now doing the keto/carnivore diet. Especially those that have osteoporosis and sarcopenia.
The interviewer is very professional! Such a pleasure to listen to all the questions she asks, even though she is a professional in the filed by herself.
This was GREAT! I have been trying to integrate ideas about the benefits of fasting and protein restriction vs the benefits of a high protein diet and this really helped me piece them together. Thank you for this window into the current state of the science and how both ideas can be true at once!!
Dr. Lyon , your conversation touched on intermittent calorie restriction for proteostasis/ autophagy. I ve been fasting four days per month for a year&1/2. The rest of the month, I eat about 155 to 160 gm/dy Prtn. At 67, Lean mass (by BIA) so far is holding @ about 155-160lbs+15-18%bf and I've watched a couple of age related skin anomalies disappear during the fasts. I'd love to hear more on this topic.
@@martigallagher7250 No, around 96 to 100 hrs, Sunday evening to Thurs) once per month. Trying for a higher level of recycling/ autophagy/ homeostasis,etc . I noticed a couple of skin anomalies that had been around a while break down after a five day about a yr and 1/2 ago so I thought I'd try again. Hunger goes away for me after the 1st full day and my best sleep, subjective and by the numbers (Oura ring) is Wednesday night. I don't go longer because 1)I find it becomes more of a deal to get the gut moving again, 2) at 67 muscle loss is a concern for me. I do continue working out through my fasts (Mon and Wed) and I'm pretty weak by Wed. I start a refeed
The guess explain in minute 52 the lack of some aminos are beneficial but not always. I think supplying the body with all amino-acids every day will age you the most and short longevity . I may be wrong though but make sense Thanks! For this kind of videos ❤
This podcast was so informative! I loved all the conversations happening and learnt so much. Would love to know more about GNc2 and proteostasis in future episodes. Thank you again Dr. Lyon, you are by far my favorite youtuber.
@@DrGabrielleLyon I wish you could make a video just for older folks about protein , more info for us exclusively . Athletes and highly trained folks are easy. I began watching you because you are experienced with older people .
I will listen to you and your guests for as long as you do this You are not only a real advocate for true science You remain humble throughout and always ready to learn and teach You’re a gift out there in the confusion and mis information You are willing to accept that more data is always needed Rate in this space Thank you
OMG!!! Soo much and for me soo complicated information.....I feel i need to go back and brush up my biology and chemistry knowledge....i love-d this chat-video....i am going to re-watch it and break it up into section to absorb the essence of it.....i need to fully understand it.....for it is sooo vital to implement it in one's life-routines.....Thank you Dr. Lyon and THANK YOU Dr.Tracy Anthony!!!👏👏👏💓
I truly appreciate the work you do , and the time you put in it .🙏 I am following you for a long time , but at this point i must say this interview , as good and pleasant it is , I found it very confusing. May I suggest that you continue this topic or you dissect it more with Dr Layman and doctors Phillips. I found your interviews with both very clear, in a very simple and understandable for all of us terminology. Thank you so much.
The protein restriction for longevity argument is based on rat studies and human questionnaires massively screwed by people eating burgers, fried breakfasts, kebabs, fish and chips, deep fried Chinese food etc. Hey they've all got protein in them!
Gabrielle you are so polite and respectful to your guests as always. But I won’t remember anything she said, I’m still sold on the realistic and intelligence of the higher protein , medium carb, diet!! If she had any body mass at all she’d probably sing a bit different song. My body knows what to do with extras of a lot of things. It probably even doesn’t need all the vitamins I give it! And I’m sure somewhere in the scientific world a possibility of a cancer resulting from that too!
Dear Gabrielle, I watched one of your interviews yesterday, and was very impressed with your interviewing style. Looking forward to this one so much, because right at the onset you stated that your views on protein ARE DIFFERENT, despite being from the “same science family, having been mentored by Don Layman”. Looking forward to hear this conversation not only for its content, but also to witness you dealing with COGNITIVE DISSONANCE live and with another person seated right in front of you. You do an incredibly valuable work of bringing in people who don’t seek to create their own platform in order to reach us the audience. THANK YOU 💚👍
Dr Peter Aitia said to NOT restrict protein intake and in fact all the latest research shows to prioritize quality protein intake for longevity and strength into older years.
Kudos for this episode Dr Lyon! True science is being prepared to doubt and challenge your own working hypothesis. Quite rare these days. Hormesis pops up as so important over and over again in the human body. This seems to be such another case (maybe). I worked as a systems safety engineer, dealing with so-called “complex systems”. None, of course anywhere near as complicated as the human body. Complex systems need special approaches. RCTs are good for selling drugs but rarely shed much light on significant mechanisms and understanding. They also fail to find root causes, and often are focussed on markers which mislead: e.g. LDL, “bad” cholesterol (which isn’t even cholesterol at all). Many of the body’s systems seem to work best with pulsatile activity. Insulin, for example. Chronically high is really bad, but you do need pulses of insulin for various reasons: zero is also not good. The same would seem to be possible for eating - pulsatile eating (whether protein or not): AKA TRE intermittent fasting, or extended fasting. Anabolism and catabolism. Absence of food (of any type) as a hormetic stressor to make the body more resilient and better at self-repairing.
You haven't had a more interesting yet humble guest on before. I listened to the entire exchange on normal speed and wouldn't have minded if you went on longer. I am not a scientist, academic or even a scholar but the conversation was so well suited to a layperson. Thank you. I appreciate that one of you mentioned that various ways of eating, particularly combining and timing macronutrients, has been in practice for ages and appear anecdotally and experientially effective towards certain biological goals (body builders for example)... and that your job as scientists is more to investigate and find the mechanisms behind the practices that yield the results. Keeping this in mind, I feel that Aryuvedic diets are such an interesting place as modern science seems to be coming full circle in support of what that ancient science has always postulated. Please invite the Dr back for a future session. Besides her scientific ability, she has a beautiful Way about her, and in turn that brings out a lovely side in you as well. You were great on this interview as well Dr Lyon. 👏🏾 👌🏽🙏🏾
Excellent to hear from Professor Anthony. I would throw one caveat in to some of these discussions, 'protein restriction' happens every day... during sleep!
@@littleyummy1517 , I perceive exactly the opposite-very engaging , two-way conversation between great minds. Dr. Lyon is excellent at translating the science for her readers based in her guests’ various expertise. Seriously, no ego in that.
When I went to college a tech economics business administration but you know I was born in 1954 and that’s when they still didn’t think women could be much more than a secretary, but I had a good mind for business and economics but then like a lot of people in my day I got married had three children And I’m trying to find myself again and I do a lot of research I am a researcher by nature I was always in the library anytime I had a problem I went to the library to solve it I still like to have hardback books of my own and not just listening to You know there’s something about having a book where you make notes in it and your line it and can go back to that I love it so I am figuring out what’s wrong with my eyes, I just love this I want to start a RUclips channel one of these days I don’t want to say the reason I haven’t yet but it Hass to do with my luxe right now because all that toxic medication they gave me took a toll on my body I mean not that I’m ugly or anything that I don’t know I think it was the steroids they were giving me cause my teeth to get bad And I’m not as worried about that but I know it’s bad for your health and I’m not gonna get implants my daughter did that and we’re both allergic to nickel that’s under that titanium and her body attacked the implants and pushed one out and was eating her jawbone away so she had to get the other one removed after all that money Anyway my health is more important to me then anything besides God and my children that I can’t enjoy anything if I’m not healthy right as you can see I’m a talker I have all his stuff in my mind in my brain it is not good to be alone all the time
It is possible to objectively determine if you are actually using (or need) more than the RDA of protein. Simply collect your urine over a period of time while eating your high protein diet and have a lab analyze the urine to determine how much nitrogen you are excreting. Dr. Ellington Darden, PhD, did this experiment while a graduate student at Florida State University. Dr. Darden was a bodybuilder and consumed about 300 grams of protein daily because he believed he needed that to build muscle. During his first postgraduate year he attended a seminar at which Dr. Harold Schendel spoke about the role of nutrition in fitness. Dr. Schendel was a professor of nutrition and had spent 4 years in Africa and elsewhere directing research on problems of protein malnutrition, with 70 published papers to his credit. Dr. Schendel disagreed with Darden's high protein diet. After some months of friendly arguments about the merits of high protein diets, Schendel challenged Darden to the above mentioned lab analysis. For 2 months, Darden kept precise records of his dietary intake and energy expenditure and collected all his urine for analysis by a graduate research team. From this experiment, Darden learned that every time he consumed more than the RDA for protein (77 grams for him at the time), the excess was excreted. They also found evidence that Darden's liver and kidneys had hypertrophied to handle the excess of protein, which organ hypertrophy has also been found in Inuit eating their native diets. Darden reported his experience in several of his books, such as Nutrition and Athletic Performance. www.amazon.com/Nutrition-Athletic-Performance-Ellington-Darden/dp/0870950584 Maybe someone who advocates and eats a high protein diet who also has access to such lab services could repeat this experiment. Its a real chance to prove that your body is using all that protein rather than converting a substantial portion (above the RDA) to carbohydrate and wasting the expensive nutrient to make sulfur & nitrogen rich urine. The human protein RDA is not exclusively based on rat studies. William Rose did experiments with humans to determine total protein needs and individual amino acid requirements. nationalmedals.org/laureate/william-c-rose/ This is well discussed in the RDA handbooks of the National Academy of Sciences. Moreover, I think it is worth noting that using rats alone to estimate human protein requirements would likely lead to gross overestimation of human protein requirements. Rats have a much higher need for protein due to their rapid growth rate compared to humans. Rats need an 18-25% protein diet by crude weight to assure a high rate of post-weaning growth. www.ncbi.nlm.nih.gov/books/NBK231925/ In contrast humans need much less protein (~10% of energy) for normal rates of growth because growth rates of humans are much lower than rats (years vs weeks, respectively). Protein requirements of each species are reflected in the difference in the protein content of each specie's mother's milk. For example, per 100 g, human milk supplies only 1 g protein whereas cow milk supplies 3.2 g protein. This occurs because bovines need more protein to support a faster rate of growth than humans. Humans grow slowly (particularly at maturity). Another error in this video is the claim that the protein RDA is set as a "bare minimum." A reading of any standard nutrition textbook or the RDA handbook dispels this claim. The RDA for protein is calculated by taking the data we have indicating mean requirements then adding a large margin to cover individual variation and unusual needs, using a Bell Curve distribution. In the case of protein, the RDA is calculated to cover the needs of about 98% of the population, which means that for the majority of people a protein intake of the RDA provides more than double actual requirements. Sure, some (about 2% of the population) will need more, but most will not. Regarding plant-protein diets, the esteemed protein researcher Millward stated after many experiments: “….we can reasonably safely conclude that, with the exception of some starchy roots, plant-based diets available in most parts of the world are capable of providing adequate protein for all ages. “….it is clear that meat-free, largely plant-based diets available in developed countries can supply protein in the amount and quality adequate for all ages. In developing countries the protein issues relate mainly to low protein levels in some staples (taro, yams and cassava etc.), but cereal-based diets, especially those based on wheat and maize, supply protein levels considerably above the requirement level.” www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/nutritional-value-of-plantbased-diets-in-relation-to-human-amino-acid-and-protein-requirements/BC1E672DD32895320E2A2C3DFA400A10
This makes sense of why spiritual hermits can thrive on a vegetarian diet and use it as a longevity practice. Then when people in a stressful environment emulate just the diet and not the rest of the practice they become sick.
Wow Archie.. you have just hit the nail on the head there. I commented about how Aryuveda would be interesting as a starting point. You seem to be looking in the same direction, as the little I know about the ancient science of Aryuveda indicates a very holistic approach and none of the components yield the best in isolation. Edit: Sorry Archie, in my excitement , I think I just rehashed what you already said🤣
@@dabeezkneez8716 I practice and teach within a Daoist school. My teacher regularly trains at Mt Wudang in Central China. Years ago he asked the priests about vegetarianism and they said they didn't recommend it. Yet at higher levels they practice it. They also gradually disperse with food and remain healthy. So it seems that as an adept progresses the practice changes and it is harmful to emulate beyond where you are truly at.
I get that studies and data are significant but I'm skeptical of using rats as a tool to decipher human nutrition. Not saying it isn't significant but I took a huge grain of salt while listening.
I as well. While it may be impossible to do these studies on humans. Simply put, rats aren't humans. To say the effects would be the same is doubtful at best.
Doctor Gabriel you need to decide what you recommend just yesterday I was watching another show where they interviewed you and you kill for proteins is the main thing for humans and not restrictions are good
Dr Lyon, There several excellent physicians and scientists who can be described as "lipidologists" who have made great strides in explaining their current understanding of fat metabolism from digestion, transportation, storage, and oxidation. Ben Bikman and (Engineer) Dave Feldman excel at describing the chemistry of lipolysis in an understandable and practical way. I value your work in the protein macronutrient to build/maintain skeletal muscle with a focus on longevity. Thank you. One of many takeaways in this interview was the useful point about taking in protein within an hour of resistance training. But that practical info-tool also begs the question about the entire protein synthesis process. Might you consider expanding on what our bodies do with proteins we consume, starting from the digestive process, to transportation, cell prioritization, use of proteins for gluconeogenesis, and finally storage of excess dietary amino acids. Thank you. 🙏🏼
Dr. Lyon, great interview, I love your channel. It got me looking into this last night and there are plenty of nice foods low in sulfur amino acids so for me one day a week I could have a large bowl of oats with fruit and then a second meal with a large baked sweet potato with various stir fried veggies on the side (avoiding certain types). Some people have a sulfur intolerance so there is quite a lot out there on what foods you could eat. Anyone else with me on trying this diet? (my wife thinks I’m nuts and this is yet another ‘fad’ of mine). At the moment I’m eating 3 meals a day of real food (not processed) and I’ve recently been making sure I get at least 1g protein per 1kg body weight (as I’m eating protein each meal I tend to get much more than that) Anyway I like the sound of getting a kind of autophogial benefit without having to fast by different food choices. It seems logical that cutting off the machinery to metabolise dietary protein could be a useful way for the body to recycle poorly functioning existing proteins.
I think the Dr was alluding that the very lack of certain amino acids may be the mechanism that makes it effective. She said no one knows yet Why bone broth is so good for you. The absence of a full amino acid profile apparently causes a stress and subsequent slowdown in synthesis that results in less 'mistakes' being made at cellular level and/or higher quality synthesis to occur. The way I understand it is, the lack of certain aminos results in more 'selectivity' and higher prioritization when synthesizing protein. 🤷🏾♂️ I could be wrong though.
@@DrGabrielleLyon hi Dr. I’m 56 and been on my new way of lifestyle change.. can we talk our can you help me with a Diet plan I don’t understand all the lingo if you could help me appreciate it thank you so much Rick I’m jealous
I like to watch videos and comment during the videos so I paused it and I like what you said about listening to somebody who was probably more knowledgeable maybe older than you wiser but you listen to his suggestions, that’s one thing when I was little I’m talking about even five and six years old I love to listen to stories people tell me about just all kinds of things it was fascinating that’s why I have so much interest in so many different things, I know a lot of people don’t understand that about me bad and has taught me to be able to talk to different type of people on different subjects and I think that’s good for a persons personality myself
I gained very useful info fr Dr Tracy interview that will help my diet in the long term. U r obviously a highly intelligent masterful interviewer but I believe there's so much more from Dr Tracy but the questions formulated hasn't really fully bring out her full potential. Hope u can bring her back again n touch on female old age protein issues. I like her n Dr Ned (Ned seems very nervous on your programe). I always have doubts abt carnivore diet linked to longetivity. Haven't see any carnivore Centenarians yet. why?
Love you Dr Lyon and your content but this video was difficult to watch and confusing. Too much proteins cause too much oxidative stress and damage? Go vegan to live longer? Dr Anthony presented interesting ideas but was vague with any specific research (long term) even though she had been doing research on protein restrictions for years. Time restricted feeding does not mean protein restrictions. I love that you ask all your guests what they eat personally. Dr Anthony skirted around that question. Complete opposite from your podcast with Dr Layman, which was amazing. Most concerning are her comments about cysteine being a sulfur based amino acid that can cause oxidative stress and shorten life span.. What about NAC? Recent research in human shows that it helps with glutathione production which is a powerful anti oxidant, and can increase life span. I am over 50 and taking gly-NAC daily- is this harmful? This kind of content actually works against what you have been working so hard to help people understand about proteins. You were so polite but I can tell you were throwing jabs Dr Lyon, please clarify
I think you should raise the video volume or add compression before uploading it, the volume is not normalized and very low by default. Also there's a hiss/white noise from the background.
Can you address the Spirulina or Chlorella Algae “claims” to be the highest source of protein (specifically 64%!!! Catharine Arnston - energy bits) Recent video claiming it doesn’t get digested and needing to be broken down like meat into amino acid. I’m so confused! Is this true or just trying to sell an expensive product as “food”?
don't think of a conspiricy of everything. Algae can be super high in protein but is often not easily bioavailable. If you want bioavalability get eggs. Unlike meat and plant protein egg protein is almost all biovailable. So even if one egg has less protein than fe a pice of chicken, it is almost all absorbed. Also good bioavailability is whey protein it's like creme de la creme if you want a quick protein boost. also don't get confused by people who have an agenda. These protein people also have an agenda. Everyone has. don't think black or white or what you would want to be true. There is good information to take out of this and good information to take from people who have a different approach. Stay critical and in best case dont use youtube as your primary source of education. If you are confused go to university and study excatly this. That's what I'm doing as all of thee informations and different opinions would just drive me nuts. Never trust anyone. Only believe when you found it out. And keep n mind that your own perseption could be flawed so calculate for that case as well.
I’ve followed Dr. Valter Longo do the idea of more protein was novel but to build muscle you need adequate protein. I’m so curious about something… is she older than you? Her description of what you had to go through to get research reminded me of my doctoral days but she doesn’t look way older than you! Help a girl out. … put a timeline on your time with Lehman please!
so excited to find a woman podcaster but after watching a few videos I am disappointed that as a non-scientist I am not getting much practical information.
Wow love the upgrade in production and the podcast. Decent mic placement Gabrielle, ideally 2-4 inches from your mouth, guest needed to get that mic in a lot closer. Don’t mean to knock you, you’ve got an epic setup and looks great but if speakers aren’t 2-4 inches away from the mic that perfect setup is lost with less than stellar audio. Keep up the great work!
I've been curious for years about rabbit starvation, and here's the thing I don't understand. Isn't eating rabbits only, very similar to the bodybuilding diet of eating chicken, broccoli, and egg whites?
I’m sorry but I can’t give a good review. Does the guest disagree with Dr Lyon’s approach? Does Dr Lyon rethink her stance? For such a smart person, I got nothing I could put into practice
Hi edward! My show is dedicated to having transparent conversations and bringing in experts to talk about their scope of practice, even if it's opposing views. I'm sorry you didn't find this episode valuable to you! Thank you for tuning in!
Understood Doc and I’ll keep tuning in cuz I follow your approach closely and believe your message. But there’s a lot of other thinking out there and I’d suggest the title of this particular show sounds like a reversal which is not helpful to those of us who are not steeped in the science. You won me over a while ago but your guest was frustrating to listen to
Awesome info we'll said, I lost a lot of weight by eating high protein and having non protein days gives the body and hormones to absorb the nutrients a d healing facts....
I learned that this is a very subtle, face- saving tactic for Dr Lyon to start changing her tune regarding high protein intake. Basically, what they're saying is there appears to be scientific evidence in rodent models that support restricting protein to extend life, health and balance weight. They have said that 'strict veganism' appears to be the only 'natural' model currently in place that will allow for such restriction of protein. Although, they are talking about 'protein' in a general way, they appear to be alluding towards restricting the 'animal' proteins which are considered 'complete' proteins as opposed to vegetable proteins ( about which it is still unclear if any truly have 'complete' amino acid profiles, when not 'processed'. Many argue for quinoa and edamame etc qs complete proteins. I wouldn't know. In my country, both are GMO crops anyway.) They conclude that restricting protein, more particularly, certain amino acids, are beneficial but also agree that they have no idea how long the restriction should be for etc. They also give the usual disclaimer limitations of the study being in mice and in the controlled lab environment. I think basically, they're just saying they are seeing exciting things in isolation in the sterile lab environment that may or may not mean anything in the real world and related to humans. It's kinda just a retraction of what Dr Lyon was touting as the 'gospel' , without really saying it. 🤷🏾♂️🙆🏽♀️
Thanks so much for your input. I actually believe that individuals do much better on a higher protein diet. This is supported in decades of human trials and especially in aging. I was very excited to have her on as there may be a roll intermittent protein restriction. Part of being a professional is being open minded to conversations. This if you use PR in my opinion must be done very carefully and not as a daily or weekly activity.
@@DrGabrielleLyon My experiance: intermittent fasting in three trainings day (with weights) a week for 14h and 200 gr till 300 gr protein 200 gr fat and 80 till 130 gr Ch. The other four days, walking 30 min till 60 min and 150 till 200 gr protein 100 gr fat and ca 30 gr Ch. I am a Male 185cm and 110kg. One day a week 22h intermittent fasting and one per month 48h intermittent fasting. I feel good with that. I have sleep apnoe and have major problem with oxygen. Carbohydrates tying twice oxygen than protein and fat.
Nothing. But i appreciate that Dr A reaffirms that science knows very little about nutrition and take those data points using lab rats with a grain of salt.
I’m assuming those living in blue zones are not in a lab… people in blue zones seem to have relatively low to moderate protein diets. Correct me if I’m wrong.
I'm still confused. I listen to high protein low protein.. just want to get through to the end That's why I end up my weight watchers I'll take my slow weight loss and eat in moderation even though I really would love to be thin and stay spin it's almost impossible anymore.
Protein restriction or timing and being smart about how and when you chose to consume protein is very different vs someone saying you should limit your protein intake, implying that consuming less protein is somehow beneficial. So called experts get this wrong all the time, our bodies need and thrive on adequate levels of protein, and consuming too little can be damaging and prevent optimal growth and recovery. However, as this video mentions, it is not smart to simply assume that eating copious amounts of protein all the time, all day long is also a benefit because its clearly not. We need to be smart and consume our protein in an intuitive way that allows our body to get the required amount but also understand the ebs and flows of how we would consume food in the past, some meals we would have access to lots of protein and others maybe none, to eat the same high amount of protein meal after meal, time after time without allowing the body to acclimate like following some diet plan is not smart, some meals go with a big steak and maybe the next not so much but the key is to fully understand the important role protein plays overall, it should be the number one, and most foundational food group in your diet, period hands down, now how much you eat of it will vary per person but the fundamental principle can be the same for everyone.
Personally, i would like to see what the REST of the "protein-containing" meal was..... results can be skewed if too many variables.... Will check to see if the research is online.....
Nothing these people who say timing is bs just get a the amount you need daily doesnt matter when if you are also doing progressive overload with weights or training til failure you will grow no matter what
" A MODEL IS A LIE THAT HELPS YOU SEE THE TRUTH" Siddhartha Mukherjee DPhil MD Tracy Anthony PhD 27:00 ☆ this is the take home message of this presentation, for me. So well said. If This Were explained and promoted in the mainstream media so much that is promoted as the truth could be better understood. Models are presented by the people and researchers doing the science Some of these researchers keep trying to select interpret and shove their data to match the model. EG climate change, how vaccines for covid-19 function
The fact that a suite of new chemo drugs are on the horizon does not excite me, we need a new approach to fighting cancer - patients have suffered enough already.
Hi Searles! My general recommendation is 1 gram of protein per ideal body weight. I have a free protocol on my website that has a list of food options if you're interested. I had Dr. Tracy on because I feel it is important to have transparent and open-minded conversations. Thank you so much for listening!
@@jerseyjim9092 That's a sound plan. I shoot for a bit over 1 gram per pound (1.1) when I am in a calorie deficit, and .9 grams per pound when I am in a calorie surplus.
@@floydald thanks Floyd. I super appreciate you saving me time. Any specifics proteins they mentioned, that they encouraged to consume and any specifics mentioned that they discouraged?
No one ever discusses longevity vs fertility. Nature doesn't care too much about long living over fecundity. Restricting protein might extend lifespan but does it diminish or extend fertility? Low protein doesn't appear to make women more fertile but the opposite. These are two different aims we need to distinguish. Yet in all the comparisons of vegan vs carnivore no one ever looks at this, only old age, nature's least cared about stage of life! We know omega three and caloric abundance improve fertility. I don't think the species priority is longevity, goes against every rule of biology. It's reproduction. It would be useful for women to know whether they can age slower re reproductive window or not.
Surprised the Dr. Lyon didn't inquire here about the specifics of the two diets fed to rats/ or probably mice, If the experiement was done in Dr. Anthony's lab.. For example, I suspect that the low sulfur diet is more akin to what mice eat in the wild, and that the standard chow is full of , well, let's just say not what mice thrive on. The other point which almost every time is not mentioned in these types of discussions regarding protein utilization, breakdown, repair etc. is, How denatured was the protein at the time of ingesting. Or, how efficiently is the body at creating perfect proteins when given an abundance denatured protein. High heat, oxidation, rancidity, are a few of the elements that contribute to denatured proteins. I understand the concept of dissonance. And with that concept in mind, the literature, for example on how proteins are denatured with high heat is totally forgotten,, for what scientist in this field is going to stop eating cooked meat/proteins, let alone eating barbecue roasted over extreme heat? Hence they simply never look at the bodies level of house cleaning ability of old proteins with the fact that eating a diet full of denatured proteins is part of the equation. And Might be a Big part of that equation too.
This is completely at odds with what Dr Peter Attia's research shows that as we age we need more protein to help prevent muscle wasting among other things.
Please note that we are extrapolating considerable amount on the back of a rodent model which are herbivores. With respect to humans there is a debate. I would say we are carnivores who have been brainwashed into becoming omnivores. Some so much that they are total herbivores. Interesting discussion albeit I don’t know that I can apply anything I’ve heard.
How is a study that gives half the amount of protein but is also half the caloric restriction be helpful? It seems like you need to just stick with one denominator not both restrictions
I don’t get it! Asking the body to manage without essential nutrients to protect the body is counterintuitive in my opinion. Giving the body high quality nutrients should protect the body. This could be coupled with intermittent fasting/time restricted feeding to ‘clean up’ ‘the nonsense’ of metabolism🤔
Just watched Gabrielle's podcast with Ted Naiman, where she claimed to be separated at birth, as they were cut from the same cloth. So this convo will be interesting.
This is absolutely fascinating although makes me laugh - I’ve only just convinced myself that eating more protein is beneficial and I’m half way down my first batch of whey protein so now I’ve upped protein to around 30% of caloric intake.
Why ONLY growth hormone? Why not a combination of thyroid, growth and progesterone? Growth hormone is not really about growth; it has over a hundred functions; the name it got was a historical aberration because someone had theorized the existence of a GH and every scientist wanted to be first at discovering it, so there were dozens of GH candidates at one point, until one got accepted. But it is not really about growth; it even mediates apoptosis. IGF1 is more about growth than GH is. EDIT: That consuming protein before exercise was not going to help muscle growth looks obvious now, but it must have been puzzling in 1997. EDIT2: I'm keto-vegetarian (NOT vegan), and my eating window is between 5pm and 6pm. That's also my wine drinking window ... ;-] EDIT3: My reply to consumer survey calls is, "Sorry, I'm not a consumer; I'm a stand-up comedian; and right now I'm sitting."
the LMNT supplement has a lot of sodium -- 1 gram sodium will be over and above the sodium one would eat in normal meal. Who is this supplement for? is it for every one of someone who is going to exercise on that day? Secondly - why so much? what is the reason?
I have find a much better option. LMNT is really „heavy“. Carnivore people use it. For One Serving, I need 3-4 Days to finish it. Way much too salty for me. I must mix it with a looooooot of water. And really, it don’t tastes very good for me. Now I take an electrolyte with creatine and vitamin c from „Go Primal“. All I can say, I Love it. It tastes so delicious and I also have creatine in it. For me, better. But this is only my opinion.
Im low carb - high protein. For my entire life. Thank uou. I feel.great
seems to be confusing to me, the more I watch. Eat more protein eat less protein, eat 30 grams of protein twice a day but eat 1 gram of protein per pound, but anything over 45 grams of protein is a waste but maybe the liver will use it. Really does anyone really know?
My dads 93 my mum is 90, they still live at home and are very fit and look after themselves and others, they have never listened a health podcast, read a health book other than articles in Readers Digest. They eat and drink what they want both have carried a little extra weight though they deny it. They drink alcohol moderately. They have never fussed about their diet but do avoid sugar and hidden sugars. They have been physically active but never went to a gym, sauna, steam room or spa or lifted weight. They rode bicycles up till their 80’s. Compared to today their early life was austere with just enough food. I hope I’ve got some of what they have.
Awesome!
They are the 2 in 10,000. Most suffer starting at 60 living that way.
I saw the words “protein restriction” and had a panic attack
😅😅😅
LOL you should know me by now :)
@@DrGabrielleLyon
😅
Just honestly never thought I’d see any contemplation of protein restricting on your channel, but it’s good to keep an open mind and explore ideas that may run counter to our own 🧠
Me too 😊
I've listened to some of your videos this week and when I saw the title, my jaw opened thinking...darn, I don't want to restrict my protein.
Great interview! Yes!! Please do a peri-post menopausal podcast with Dr Tracy Anthony on nutrition, muscle/bone retention, and protein needs for optimal health as we age. Thank you!
Seconded! I'm going to be 60 next month and just started going to the gym regularly a couple of months ago.
Yes please do more interviews with Tracy Anthony PhD
As a Personal Trainer, your channel has helped tremendously with assisting my clients with nutritional guidance! Love all your content!
Love the sound quality. Its like I was there with you, listening to two people who know a lot about the subject they are talking about.
Another great video by one of my favorite Dr's! Thank you, Dr. Lyon! My favorite part about all of these videos by my favorite dr's are that they interview to ask questions and try to keep learning, whether they already know what they're talking about or not. None of them act like they're the last word on anything that they talk or ask about. Very refreshing! No egos doing battle. The modesty and humbleness of these super smart dr's is another favorite part of these videos. Thank you two great dr's for this video!
One of Dr Lyon's best episodes
Two world class women. I read Dr. Lyon’s newsletter in full every time. Thank you for the best podcast out there.
@Ruth Biafora it's irrelevant that they are both women, stop being sexist.
Why is literally mentioning their gender a problem? Your are the kind of guy who will shit on women's accomplishment and have no problem when men are mentioned instread. Stating they are women is NOT a sexist move @@littleyummy1517
Love listening to you two talk in your science lingo. As if its a foreign language which it is to most people. My Bachelor of science was in food science technology and nutrition so it cracks me up when you two are talking like this. Great and informative, I’m eating it up, zero calories.
I love that both of you are open minded and open to discussion .. real scientists and intellectuals.😊❤
off topic but science is the main reason i believe in a creator , humans and other organisms and the workings of our bodies and how we interact with our environments is to complex to have happened by chance. a supremely intelligent being must have created us.
This seemed to me to be a real scientific way of saying "everything in balance and reason, mix it up".
I never heard her say what her macronutrient breakdown that she eats? She said no diet is a bad diet! Intermittent fasting and two meals a day! So how much freakin protein is appropriate? That is why everyone is watching this video so we are not hurting ourselves with all this protein!
Important and helpful interview. Some of the comments are not acknowledging the nuance in developing the diet. Other commenters get it, though, when they say that a fast, then feed approach may be optimal because it accomplishes both restriction (fasting) and repletion (feeding). Thanks, Dr. Lyon, for posting this.
This is taking me back to my university days. The hated days of microfiche and card catelogues. Those days sucked in some ways but getting lost in the campus library reading journals and microfiche.
Would love to see studies done on post menopausal women raised on the SAD diet now doing the keto/carnivore diet. Especially those that have osteoporosis and sarcopenia.
The interviewer
is very professional! Such a pleasure to listen to all the questions she asks, even though she is a professional in the filed by herself.
Interesting topic, interesting guest who doesn't buy her own research. Lol
This was GREAT! I have been trying to integrate ideas about the benefits of fasting and protein restriction vs the benefits of a high protein diet and this really helped me piece them together. Thank you for this window into the current state of the science and how both ideas can be true at once!!
Dr. Lyon , your conversation touched on intermittent calorie restriction for proteostasis/ autophagy. I ve been fasting four days per month for a year&1/2. The rest of the month, I eat about 155 to 160 gm/dy Prtn. At 67, Lean mass (by BIA) so far is holding @ about 155-160lbs+15-18%bf and I've watched a couple of age related skin anomalies disappear during the fasts. I'd love to hear more on this topic.
Are you doing approximately 1-day per week of fasting or 4 contiguous days? Thanks!
@@martigallagher7250 No, around 96 to 100 hrs, Sunday evening to Thurs) once per month. Trying for a higher level of recycling/ autophagy/ homeostasis,etc
. I noticed a couple of skin anomalies that had been around a while break down after a five day about a yr and 1/2 ago so I thought I'd try again. Hunger goes away for me after the 1st full day and my best sleep, subjective and by the numbers (Oura ring) is Wednesday night. I don't go longer because 1)I find it becomes more of a deal to get the gut moving again, 2) at 67 muscle loss is a concern for me. I do continue working out through my fasts (Mon and Wed) and I'm pretty weak by Wed. I start a refeed
The guess explain in minute 52 the lack of some aminos are beneficial but not always. I think supplying the body with all amino-acids every day will age you the most and short longevity . I may be wrong though but make sense
Thanks! For this kind of videos ❤
You should have this lady on at the same time as your mentor, protein guru Donald Layman.
This podcast was so informative! I loved all the conversations happening and learnt so much. Would love to know more about GNc2 and proteostasis in future episodes. Thank you again Dr. Lyon, you are by far my favorite youtuber.
Thank you so much!
@@DrGabrielleLyon I wish you could make a video just for older folks about protein , more info for us exclusively . Athletes and highly trained folks are easy. I began watching you because you are experienced with older people .
I will listen to you and your guests for as long as you do this
You are not only a real advocate for true science
You remain humble throughout and always ready to learn and teach
You’re a gift out there in the confusion and mis information
You are willing to accept that more data is always needed
Rate in this space
Thank you
When increasing Protein Intake, definitely a priority of increasing and maintaining adequate clean water (H2O) intake
OMG!!! Soo much and for me soo complicated information.....I feel i need to go back and brush up my biology and chemistry knowledge....i love-d this chat-video....i am going to re-watch it and break it up into section to absorb the essence of it.....i need to fully understand it.....for it is sooo vital to implement it in one's life-routines.....Thank you Dr. Lyon and THANK YOU Dr.Tracy Anthony!!!👏👏👏💓
I truly appreciate the work you do , and the time you put in it .🙏
I am following you for a long time , but at this point i must say this interview , as good and pleasant it is , I found it very confusing. May I suggest that you continue this topic or you dissect it more with Dr Layman and doctors Phillips. I found your interviews with both very clear, in a very simple and understandable for all of us terminology. Thank you so much.
As you age your protien and cholesterol requirements increase. You need it for your brain and to avoid sarcopenia (muscle loss).
The protein restriction for longevity argument is based on rat studies and human questionnaires massively screwed by people eating burgers, fried breakfasts, kebabs, fish and chips, deep fried Chinese food etc. Hey they've all got protein in them!
Gabrielle you are so polite and respectful to your guests as always. But I won’t remember anything she said, I’m still sold on the realistic and intelligence of the higher protein , medium carb, diet!! If she had any body mass at all she’d probably sing a bit different song. My body knows what to do with extras of a lot of things. It probably even doesn’t need all the vitamins I give it! And I’m sure somewhere in the scientific world a possibility of a cancer resulting from that too!
Thank you for such an insightful episode! You are both doing wonderful work and coming with different perspectives lead to such informative subjects.
Thank you so much !
Dear Gabrielle, I watched one of your interviews yesterday, and was very impressed with your interviewing style. Looking forward to this one so much, because right at the onset you stated that your views on protein ARE DIFFERENT, despite being from the “same science family, having been mentored by Don Layman”. Looking forward to hear this conversation not only for its content, but also to witness you dealing with COGNITIVE DISSONANCE live and with another person seated right in front of you. You do an incredibly valuable work of bringing in people who don’t seek to create their own platform in order to reach us the audience. THANK YOU 💚👍
To hear 2 great protein minded experts exchange info is awesome. Thanks for this !!
Dr Peter Aitia said to NOT restrict protein intake and in fact all the latest research shows to prioritize quality protein intake for longevity and strength into older years.
Kudos for this episode Dr Lyon! True science is being prepared to doubt and challenge your own working hypothesis. Quite rare these days. Hormesis pops up as so important over and over again in the human body. This seems to be such another case (maybe). I worked as a systems safety engineer, dealing with so-called “complex systems”. None, of course anywhere near as complicated as the human body. Complex systems need special approaches. RCTs are good for selling drugs but rarely shed much light on significant mechanisms and understanding. They also fail to find root causes, and often are focussed on markers which mislead: e.g. LDL, “bad” cholesterol (which isn’t even cholesterol at all). Many of the body’s systems seem to work best with pulsatile activity. Insulin, for example. Chronically high is really bad, but you do need pulses of insulin for various reasons: zero is also not good. The same would seem to be possible for eating - pulsatile eating (whether protein or not): AKA TRE intermittent fasting, or extended fasting. Anabolism and catabolism. Absence of food (of any type) as a hormetic stressor to make the body more resilient and better at self-repairing.
You haven't had a more interesting yet humble guest on before. I listened to the entire exchange on normal speed and wouldn't have minded if you went on longer. I am not a scientist, academic or even a scholar but the conversation was so well suited to a layperson. Thank you. I appreciate that one of you mentioned that various ways of eating, particularly combining and timing macronutrients, has been in practice for ages and appear anecdotally and experientially effective towards certain biological goals (body builders for example)... and that your job as scientists is more to investigate and find the mechanisms behind the practices that yield the results. Keeping this in mind, I feel that Aryuvedic diets are such an interesting place as modern science seems to be coming full circle in support of what that ancient science has always postulated. Please invite the Dr back for a future session. Besides her scientific ability, she has a beautiful Way about her, and in turn that brings out a lovely side in you as well. You were great on this interview as well Dr Lyon. 👏🏾 👌🏽🙏🏾
Thank you so much for taking the time to watch. I agree she is amazing as a human and scientist.
"Aryuvedic" refers to whatever a shyster from India steals from Western science and then re-markets as "ancient Indian wisdom".
Just the right amount.
Ate more then I thought I should.
Was so tired.
Excellent to hear from Professor Anthony. I would throw one caveat in to some of these discussions, 'protein restriction' happens every day... during sleep!
Dr Lyon just knocking it out the the park again with a really good guest and really good Q&A. Bravo!
Thank you! I'm glad you're enjoying these conversations!
@@DrGabrielleLyon Yeah but reel in your Ego, we want to hear the guest, not you.
@@littleyummy1517 , I perceive exactly the opposite-very engaging , two-way conversation between great minds. Dr. Lyon is excellent at translating the science for her readers based in her guests’ various expertise. Seriously, no ego in that.
Much respect always Dr
Great podcast! Keep it coming all things protein related please..!
When I went to college a tech economics business administration but you know I was born in 1954 and that’s when they still didn’t think women could be much more than a secretary, but I had a good mind for business and economics but then like a lot of people in my day I got married had three children And I’m trying to find myself again and I do a lot of research I am a researcher by nature I was always in the library anytime I had a problem I went to the library to solve it I still like to have hardback books of my own and not just listening to
You know there’s something about having a book where you make notes in it and your line it and can go back to that I love it so I am figuring out what’s wrong with my eyes, I just love this I want to start a RUclips channel one of these days I don’t want to say the reason I haven’t yet but it Hass to do with my luxe right now because all that toxic medication they gave me took a toll on my body I mean not that I’m ugly or anything that I don’t know I think it was the steroids they were giving me cause my teeth to get bad
And I’m not as worried about that but I know it’s bad for your health and I’m not gonna get implants my daughter did that and we’re both allergic to nickel that’s under that titanium and her body attacked the implants and pushed one out and was eating her jawbone away so she had to get the other one removed after all that money Anyway my health is more important to me then anything besides God and my children that I can’t enjoy anything if I’m not healthy right as you can see I’m a talker I have all his stuff in my mind in my brain it is not good to be alone all the time
It is possible to objectively determine if you are actually using (or need) more than the RDA of protein. Simply collect your urine over a period of time while eating your high protein diet and have a lab analyze the urine to determine how much nitrogen you are excreting. Dr. Ellington Darden, PhD, did this experiment while a graduate student at Florida State University. Dr. Darden was a bodybuilder and consumed about 300 grams of protein daily because he believed he needed that to build muscle. During his first postgraduate year he attended a seminar at which Dr. Harold Schendel spoke about the role of nutrition in fitness. Dr. Schendel was a professor of nutrition and had spent 4 years in Africa and elsewhere directing research on problems of protein malnutrition, with 70 published papers to his credit. Dr. Schendel disagreed with Darden's high protein diet. After some months of friendly arguments about the merits of high protein diets, Schendel challenged Darden to the above mentioned lab analysis. For 2 months, Darden kept precise records of his dietary intake and energy expenditure and collected all his urine for analysis by a graduate research team. From this experiment, Darden learned that every time he consumed more than the RDA for protein (77 grams for him at the time), the excess was excreted. They also found evidence that Darden's liver and kidneys had hypertrophied to handle the excess of protein, which organ hypertrophy has also been found in Inuit eating their native diets. Darden reported his experience in several of his books, such as Nutrition and Athletic Performance. www.amazon.com/Nutrition-Athletic-Performance-Ellington-Darden/dp/0870950584
Maybe someone who advocates and eats a high protein diet who also has access to such lab services could repeat this experiment. Its a real chance to prove that your body is using all that protein rather than converting a substantial portion (above the RDA) to carbohydrate and wasting the expensive nutrient to make sulfur & nitrogen rich urine.
The human protein RDA is not exclusively based on rat studies. William Rose did experiments with humans to determine total protein needs and individual amino acid requirements. nationalmedals.org/laureate/william-c-rose/ This is well discussed in the RDA handbooks of the National Academy of Sciences.
Moreover, I think it is worth noting that using rats alone to estimate human protein requirements would likely lead to gross overestimation of human protein requirements. Rats have a much higher need for protein due to their rapid growth rate compared to humans. Rats need an 18-25% protein diet by crude weight to assure a high rate of post-weaning growth. www.ncbi.nlm.nih.gov/books/NBK231925/ In contrast humans need much less protein (~10% of energy) for normal rates of growth because growth rates of humans are much lower than rats (years vs weeks, respectively).
Protein requirements of each species are reflected in the difference in the protein content of each specie's mother's milk. For example, per 100 g, human milk supplies only 1 g protein whereas cow milk supplies 3.2 g protein. This occurs because bovines need more protein to support a faster rate of growth than humans. Humans grow slowly (particularly at maturity).
Another error in this video is the claim that the protein RDA is set as a "bare minimum." A reading of any standard nutrition textbook or the RDA handbook dispels this claim. The RDA for protein is calculated by taking the data we have indicating mean requirements then adding a large margin to cover individual variation and unusual needs, using a Bell Curve distribution. In the case of protein, the RDA is calculated to cover the needs of about 98% of the population, which means that for the majority of people a protein intake of the RDA provides more than double actual requirements. Sure, some (about 2% of the population) will need more, but most will not.
Regarding plant-protein diets, the esteemed protein researcher Millward stated after many experiments: “….we can reasonably safely conclude that, with the exception of some starchy roots, plant-based diets available in most parts of the world are capable of providing adequate protein for all ages.
“….it is clear that meat-free, largely plant-based diets available in developed countries can supply protein in the amount and quality adequate for all ages. In developing countries the protein issues relate mainly to low protein levels in some staples (taro, yams and cassava etc.), but cereal-based diets, especially those based on wheat and maize, supply protein levels considerably above the requirement level.” www.cambridge.org/core/journals/proceedings-of-the-nutrition-society/article/nutritional-value-of-plantbased-diets-in-relation-to-human-amino-acid-and-protein-requirements/BC1E672DD32895320E2A2C3DFA400A10
This makes sense of why spiritual hermits can thrive on a vegetarian diet and use it as a longevity practice. Then when people in a stressful environment emulate just the diet and not the rest of the practice they become sick.
That’s a great point!
Wow Archie.. you have just hit the nail on the head there. I commented about how Aryuveda would be interesting as a starting point. You seem to be looking in the same direction, as the little I know about the ancient science of Aryuveda indicates a very holistic approach and none of the components yield the best in isolation.
Edit: Sorry Archie, in my excitement , I think I just rehashed what you already said🤣
@@dabeezkneez8716
I practice and teach within a Daoist school. My teacher regularly trains at Mt Wudang in Central China. Years ago he asked the priests about vegetarianism and they said they didn't recommend it. Yet at higher levels they practice it. They also gradually disperse with food and remain healthy. So it seems that as an adept progresses the practice changes and it is harmful to emulate beyond where you are truly at.
Wow , exactly worth a mullion papers
Actualy, the new study sayz, that the old India brahmans, in old history, have been big eaters of red meat.@@Ichuanam
I get that studies and data are significant but I'm skeptical of using rats as a tool to decipher human nutrition. Not saying it isn't significant but I took a huge grain of salt while listening.
Yes, Bret Weinstein has much to say on this: m.ruclips.net/video/hKTV2R6TT0Y/видео.html
I as well. While it may be impossible to do these studies on humans. Simply put, rats aren't humans. To say the effects would be the same is doubtful at best.
Yes, and nobody does the protein restriction studies on cats or dogs longevity...
Absolutely a good point rodent models are rodent models.
I would love to see you, Dr. Lyon expand on fgf21......??? Thanks!
Doctor Gabriel you need to decide what you recommend just yesterday I was watching another show where they interviewed you and you kill for proteins is the main thing for humans and not restrictions are good
Dr Lyon,
There several excellent physicians and scientists who can be described as "lipidologists" who have made great strides in explaining their current understanding of fat metabolism from digestion, transportation, storage, and oxidation. Ben Bikman and (Engineer) Dave Feldman excel at describing the chemistry of lipolysis in an understandable and practical way.
I value your work in the protein macronutrient to build/maintain skeletal muscle with a focus on longevity. Thank you. One of many takeaways in this interview was the useful point about taking in protein within an hour of resistance training. But that practical info-tool also begs the question about the entire protein synthesis process.
Might you consider expanding on what our bodies do with proteins we consume, starting from the digestive process, to transportation, cell prioritization, use of proteins for gluconeogenesis, and finally storage of excess dietary amino acids.
Thank you. 🙏🏼
An idea for another guest - Dr Stacy Sims to talk with about female nutrition and training especially during peri and post menopause.
Really interesting conversation! A summary of the main points raised would be gratefully received. Has raised many new questions.
Ok… this interview did not help with all the confusion out there at all. Interesting to listen to the science but of no use to the general public.
Very Enlightening ⭐️
Dr. Lyon, great interview, I love your channel. It got me looking into this last night and there are plenty of nice foods low in sulfur amino acids so for me one day a week I could have a large bowl of oats with fruit and then a second meal with a large baked sweet potato with various stir fried veggies on the side (avoiding certain types). Some people have a sulfur intolerance so there is quite a lot out there on what foods you could eat.
Anyone else with me on trying this diet? (my wife thinks I’m nuts and this is yet another ‘fad’ of mine).
At the moment I’m eating 3 meals a day of real food (not processed) and I’ve recently been making sure I get at least 1g protein per 1kg body weight (as I’m eating protein each meal I tend to get much more than that)
Anyway I like the sound of getting a kind of autophogial benefit without having to fast by different food choices. It seems logical that cutting off the machinery to metabolise dietary protein could be a useful way for the body to recycle poorly functioning existing proteins.
This was a great podcast. Didnt know that bone broth did not have a complete amino acid profile, going to have to up my protein amount now.
I think the Dr was alluding that the very lack of certain amino acids may be the mechanism that makes it effective. She said no one knows yet Why bone broth is so good for you. The absence of a full amino acid profile apparently causes a stress and subsequent slowdown in synthesis that results in less 'mistakes' being made at cellular level and/or higher quality synthesis to occur. The way I understand it is, the lack of certain aminos results in more 'selectivity' and higher prioritization when synthesizing protein. 🤷🏾♂️ I could be wrong though.
Kyle thanks so much for taking the time to watch and listen I really appreciate it.
@@DrGabrielleLyon hi Dr. I’m 56 and been on my new way of lifestyle change.. can we talk our can you help me with a Diet plan I don’t understand all the lingo if you could help me appreciate it thank you so much Rick I’m jealous
So then legumes are just as good too.
Dr. Longo . Fasting less protein. Live longer ? Interesting
I like to watch videos and comment during the videos so I paused it and I like what you said about listening to somebody who was probably more knowledgeable maybe older than you wiser but you listen to his suggestions, that’s one thing when I was little I’m talking about even five and six years old I love to listen to stories people tell me about just all kinds of things it was fascinating that’s why I have so much interest in so many different things, I know a lot of people don’t understand that about me bad and has taught me to be able to talk to different type of people on different subjects and I think that’s good for a persons personality myself
What does Dr. Lyon eat in detail in a day? 👍🏽
Great discussion. Thx. Kudos Ladies.
I gained very useful info fr Dr Tracy interview that will help my diet in the long term. U r obviously a highly intelligent masterful interviewer but I believe there's so much more from Dr Tracy but the questions formulated hasn't really fully bring out her full potential. Hope u can bring her back again n touch on female old age protein issues. I like her n Dr Ned (Ned seems very nervous on your programe). I always have doubts abt carnivore diet linked to longetivity. Haven't see any carnivore Centenarians yet. why?
EXCELLENT CONVERSATION!
Which foods contain sulfur amino acids?
And for how long would you have to restrict the aforementioned?
Great episode! Love it!!
Hay !!! I know you !
Love you Dr Lyon and your content but this video was difficult to watch and confusing. Too much proteins cause too much oxidative stress and damage? Go vegan to live longer? Dr Anthony presented interesting ideas but was vague with any specific research (long term) even though she had been doing research on protein restrictions for years. Time restricted feeding does not mean protein restrictions. I love that you ask all your guests what they eat personally. Dr Anthony skirted around that question. Complete opposite from your podcast with Dr Layman, which was amazing. Most concerning are her comments about cysteine being a sulfur based amino acid that can cause oxidative stress and shorten life span.. What about NAC? Recent research in human shows that it helps with glutathione production which is a powerful anti oxidant, and can increase life span.
I am over 50 and taking gly-NAC daily- is this harmful?
This kind of content actually works against what you have been working so hard to help people understand about proteins. You were so polite but I can tell you were throwing jabs
Dr Lyon, please clarify
What anniversary of your 29th birthday will you be celebrating next? I’ll be celebrating the 40 anniversary of my 29th this Oct. 😎
I LOVE THAT
I think you should raise the video volume or add compression before uploading it, the volume is not normalized and very low by default. Also there's a hiss/white noise from the background.
Can you address the Spirulina or Chlorella Algae “claims” to be the highest source of protein (specifically 64%!!! Catharine Arnston - energy bits) Recent video claiming it doesn’t get digested and needing to be broken down like meat into amino acid. I’m so confused! Is this true or just trying to sell an expensive product as “food”?
Meat, eggs usually highly available but plant protein isn’t highly available at all. She’s probably selling a product.
don't think of a conspiricy of everything. Algae can be super high in protein but is often not easily bioavailable. If you want bioavalability get eggs. Unlike meat and plant protein egg protein is almost all biovailable. So even if one egg has less protein than fe a pice of chicken, it is almost all absorbed. Also good bioavailability is whey protein it's like creme de la creme if you want a quick protein boost. also don't get confused by people who have an agenda. These protein people also have an agenda. Everyone has. don't think black or white or what you would want to be true. There is good information to take out of this and good information to take from people who have a different approach. Stay critical and in best case dont use youtube as your primary source of education. If you are confused go to university and study excatly this. That's what I'm doing as all of thee informations and different opinions would just drive me nuts. Never trust anyone. Only believe when you found it out. And keep n mind that your own perseption could be flawed so calculate for that case as well.
Dr Berg (?) whey isolate is really bad for the liver.
I’ve followed Dr. Valter Longo do the idea of more protein was novel but to build muscle you need adequate protein. I’m so curious about something… is she older than you? Her description of what you had to go through to get research reminded me of my doctoral days but she doesn’t look way older than you! Help a girl out. … put a timeline on your time with Lehman please!
so excited to find a woman podcaster but after watching a few videos I am disappointed that as a non-scientist I am not getting much practical information.
Podcasts are mainly a waste of time
Wow love the upgrade in production and the podcast. Decent mic placement Gabrielle, ideally 2-4 inches from your mouth, guest needed to get that mic in a lot closer. Don’t mean to knock you, you’ve got an epic setup and looks great but if speakers aren’t 2-4 inches away from the mic that perfect setup is lost with less than stellar audio. Keep up the great work!
Thank you so much for that input!!
I've been curious for years about rabbit starvation, and here's the thing I don't understand. Isn't eating rabbits only, very similar to the bodybuilding diet of eating chicken, broccoli, and egg whites?
I’m sorry but I can’t give a good review. Does the guest disagree with Dr Lyon’s approach? Does Dr Lyon rethink her stance? For such a smart person, I got nothing I could put into practice
Hi edward! My show is dedicated to having transparent conversations and bringing in experts to talk about their scope of practice, even if it's opposing views. I'm sorry you didn't find this episode valuable to you! Thank you for tuning in!
Understood Doc and I’ll keep tuning in cuz I follow your approach closely and believe your message. But there’s a lot of other thinking out there and I’d suggest the title of this particular show sounds like a reversal which is not helpful to those of us who are not steeped in the science. You won me over a while ago but your guest was frustrating to listen to
I'm confused, so should I take more protein like Dr. Lyon says or should I take less like Tracy Anthony says? Thanks.
Depends on your individual circumstances. Dr Tracy herself said she tends to follow the TRE diet when she's not in training.
Awesome info we'll said, I lost a lot of weight by eating high protein and having non protein days gives the body and hormones to absorb the nutrients a d healing facts....
Has anyone learned anything about protein restriction in this video? If so, please inform.
I learned that this is a very subtle, face- saving tactic for Dr Lyon to start changing her tune regarding high protein intake. Basically, what they're saying is there appears to be scientific evidence in rodent models that support restricting protein to extend life, health and balance weight. They have said that 'strict veganism' appears to be the only 'natural' model currently in place that will allow for such restriction of protein. Although, they are talking about 'protein' in a general way, they appear to be alluding towards restricting the 'animal' proteins which are considered 'complete' proteins as opposed to vegetable proteins ( about which it is still unclear if any truly have 'complete' amino acid profiles, when not 'processed'. Many argue for quinoa and edamame etc qs complete proteins. I wouldn't know. In my country, both are GMO crops anyway.) They conclude that restricting protein, more particularly, certain amino acids, are beneficial but also agree that they have no idea how long the restriction should be for etc. They also give the usual disclaimer limitations of the study being in mice and in the controlled lab environment. I think basically, they're just saying they are seeing exciting things in isolation in the sterile lab environment that may or may not mean anything in the real world and related to humans. It's kinda just a retraction of what Dr Lyon was touting as the 'gospel' , without really saying it. 🤷🏾♂️🙆🏽♀️
Thanks so much for your input. I actually believe that individuals do much better on a higher protein diet. This is supported in decades of human trials and especially in aging. I was very excited to have her on as there may be a roll intermittent protein restriction. Part of being a professional is being open minded to conversations. This if you use PR in my opinion must be done very carefully and not as a daily or weekly activity.
@@DrGabrielleLyon My experiance: intermittent fasting in three trainings day (with weights) a week for 14h and 200 gr till 300 gr protein 200 gr fat and 80 till 130 gr Ch. The other four days, walking 30 min till 60 min and 150 till 200 gr protein 100 gr fat and ca 30 gr Ch. I am a Male 185cm and 110kg. One day a week 22h intermittent fasting and one per month 48h intermittent fasting. I feel good with that. I have sleep apnoe and have major problem with oxygen. Carbohydrates tying twice oxygen than protein and fat.
Nothing. But i appreciate that Dr A reaffirms that science knows very little about nutrition and take those data points using lab rats with a grain of salt.
Thank you so very much. Fascinating interview..gave me much to think about.
Thanks so much for taking the time to watch I know how valuable your time is.
She has gorgeous skin!
I taught deficit calorie mattered when cleaning the body.
Not fasting necessarily as she said.
I’m assuming those living in blue zones are not in a lab… people in blue zones seem to have relatively low to moderate protein diets. Correct me if I’m wrong.
You are right
I'm still confused. I listen to high protein low protein.. just want to get through to the end That's why I end up my weight watchers I'll take my slow weight loss and eat in moderation even though I really would love to be thin and stay spin it's almost impossible anymore.
Protein restriction or timing and being smart about how and when you chose to consume protein is very different vs someone saying you should limit your protein intake, implying that consuming less protein is somehow beneficial. So called experts get this wrong all the time, our bodies need and thrive on adequate levels of protein, and consuming too little can be damaging and prevent optimal growth and recovery.
However, as this video mentions, it is not smart to simply assume that eating copious amounts of protein all the time, all day long is also a benefit because its clearly not. We need to be smart and consume our protein in an intuitive way that allows our body to get the required amount but also understand the ebs and flows of how we would consume food in the past, some meals we would have access to lots of protein and others maybe none, to eat the same high amount of protein meal after meal, time after time without allowing the body to acclimate like following some diet plan is not smart, some meals go with a big steak and maybe the next not so much but the key is to fully understand the important role protein plays overall, it should be the number one, and most foundational food group in your diet, period hands down, now how much you eat of it will vary per person but the fundamental principle can be the same for everyone.
Personally, i would like to see what the REST of the "protein-containing" meal was.....
results can be skewed if too many variables....
Will check to see if the research is online.....
As far as I can tell from your talk, you have to have protein after a workout. What happens if you don’t have it. You won’t build muscle ?
Nothing these people who say timing is bs just get a the amount you need daily doesnt matter when if you are also doing progressive overload with weights or training til failure you will grow no matter what
@@mucleboy0151 this is what I read too. But thanx for reaching out bro 👌🏻
" A MODEL IS A LIE THAT HELPS YOU SEE THE TRUTH"
Siddhartha Mukherjee DPhil MD
Tracy Anthony PhD
27:00
☆ this is the take home message of this presentation, for me.
So well said.
If This Were explained and promoted in the mainstream media so much that is promoted as the truth could be better understood. Models are presented by the people and researchers doing the science Some of these researchers keep trying to select interpret and shove their data to match the model.
EG climate change, how vaccines for covid-19 function
Interesting how both opposite sides can resolve so many conditions and diseases; being a vegan OR being a carnivore.
I had to look at the date this video was uploaded because I thought it was an April Fool's joke😮
There's a strange tention between these two
The fact that a suite of new chemo drugs are on the horizon does not excite me, we need a new approach to fighting cancer - patients have suffered enough already.
So how much protein should we eat?
Hi Searles! My general recommendation is 1 gram of protein per ideal body weight. I have a free protocol on my website that has a list of food options if you're interested. I had Dr. Tracy on because I feel it is important to have transparent and open-minded conversations. Thank you so much for listening!
@@DrGabrielleLyon what about for a bodybuilder in his mid fifties?
@@NJN23 I'm in my 60s and trying to build muscle. I shoot for 1 gr per pound of ideal bodyweight.
@@jerseyjim9092 That's a sound plan. I shoot for a bit over 1 gram per pound (1.1) when I am in a calorie deficit, and .9 grams per pound when I am in a calorie surplus.
Unfortunately no real usable information.
Ok I’ll stop watching. The more you tube vids I see the more I get confused.
Thanks for saving my time!!! What did they say about protein restriction?
A obscure and difficult thing to accomplish, eat protein and live long 😀
@@floydald thanks Floyd. I super appreciate you saving me time. Any specifics proteins they mentioned, that they encouraged to consume and any specifics mentioned that they discouraged?
One would need to be on a strict vegan diet, l would just follow Dr Lyons’s protocol.
No one ever discusses longevity vs fertility. Nature doesn't care too much about long living over fecundity. Restricting protein might extend lifespan but does it diminish or extend fertility? Low protein doesn't appear to make women more fertile but the opposite. These are two different aims we need to distinguish. Yet in all the comparisons of vegan vs carnivore no one ever looks at this, only old age, nature's least cared about stage of life! We know omega three and caloric abundance improve fertility. I don't think the species priority is longevity, goes against every rule of biology. It's reproduction. It would be useful for women to know whether they can age slower re reproductive window or not.
Surprised the Dr. Lyon didn't inquire here about the specifics of the two diets fed to rats/ or probably mice, If the experiement was done in Dr. Anthony's lab.. For example, I suspect that the low sulfur diet is more akin to what mice eat in the wild, and that the standard chow is full of , well, let's just say not what mice thrive on.
The other point which almost every time is not mentioned in these types of discussions regarding protein utilization, breakdown, repair etc. is, How denatured was the protein at the time of ingesting. Or, how efficiently is the body at creating perfect proteins when given an abundance denatured protein. High heat, oxidation, rancidity, are a few of the elements that contribute to denatured proteins. I understand the concept of dissonance. And with that concept in mind, the literature, for example on how proteins are denatured with high heat is totally forgotten,, for what scientist in this field is going to stop eating cooked meat/proteins, let alone eating barbecue roasted over extreme heat? Hence they simply never look at the bodies level of house cleaning ability of old proteins with the fact that eating a diet full of denatured proteins is part of the equation. And Might be a Big part of that equation too.
Wonderful
This is completely at odds with what Dr Peter Attia's research shows that as we age we need more protein to help prevent muscle wasting among other things.
You need to lift weight and strength train, to prevent muscle wasting.
Please note that we are extrapolating considerable amount on the back of a rodent model which are herbivores. With respect to humans there is a debate. I would say we are carnivores who have been brainwashed into becoming omnivores. Some so much that they are total herbivores. Interesting discussion albeit I don’t know that I can apply anything I’ve heard.
Fruits, vegetables and meat all have amino acids so what food does not?
It's about having the 9 essential amino acids.
How is a study that gives half the amount of protein but is also half the caloric restriction be helpful? It seems like you need to just stick with one denominator not both restrictions
I don’t get it! Asking the body to manage without essential nutrients to protect the body is counterintuitive in my opinion. Giving the body high quality nutrients should protect the body. This could be coupled with intermittent fasting/time restricted feeding to ‘clean up’ ‘the nonsense’ of metabolism🤔
Just watched Gabrielle's podcast with Ted Naiman, where she claimed to be separated at birth, as they were cut from the same cloth. So this convo will be interesting.
This is absolutely fascinating although makes me laugh - I’ve only just convinced myself that eating more protein is beneficial and I’m half way down my first batch of whey protein so now I’ve upped protein to around 30% of caloric intake.
Why ONLY growth hormone? Why not a combination of thyroid, growth and progesterone? Growth hormone is not really about growth; it has over a hundred functions; the name it got was a historical aberration because someone had theorized the existence of a GH and every scientist wanted to be first at discovering it, so there were dozens of GH candidates at one point, until one got accepted. But it is not really about growth; it even mediates apoptosis. IGF1 is more about growth than GH is.
EDIT: That consuming protein before exercise was not going to help muscle growth looks obvious now, but it must have been puzzling in 1997.
EDIT2: I'm keto-vegetarian (NOT vegan), and my eating window is between 5pm and 6pm. That's also my wine drinking window ... ;-]
EDIT3: My reply to consumer survey calls is, "Sorry, I'm not a consumer; I'm a stand-up comedian; and right now I'm sitting."
the LMNT supplement has a lot of sodium -- 1 gram sodium will be over and above the sodium one would eat in normal meal. Who is this supplement for? is it for every one of someone who is going to exercise on that day? Secondly - why so much? what is the reason?
I have find a much better option. LMNT is really „heavy“. Carnivore people use it. For One Serving, I need 3-4 Days to finish it. Way much too salty for me. I must mix it with a looooooot of water. And really, it don’t tastes very good for me.
Now I take an electrolyte with creatine and vitamin c from „Go Primal“. All I can say, I Love it. It tastes so delicious and I also have creatine in it. For me, better. But this is only my opinion.
Well the WEF will love this