Not even a med student, but this stuff is generally interesting, it might sound stupid but it would also be cool to see some dummed down videos that anyone could understand
See the whole series at www.medcram.com along with other top quality videos including reviews in pulmonary, cardiology, infectious disease, and hematology!
just i have one qus, for cushing syndrome there is no influence on zg just on zf and zr, so i think the aldosterone level will be normal since it stimulated by high K not by acth. thanks for all the effort
When Blood pressure decrease or hypokalimia that stimuli Renin_ angiotensin system in kidney to secret Renin that convert to angiotensin 2 to affect adrinal cortex and produce aldosterone
Hello and thank you. I have had a brain tumor removed, most of it. I can't stay awake much. I was looking around and was wondering if what could cause the tumor is the lack of cortex or the Adrenal Gland itself not feeding me enough cortex. Also is there anyway to work on the Adrenal Gland and help it out.. Thank you
Hi This is the first time I actually understood Addison's Disease in which I've had for 14 years. It was absolutely fantastic. Easy for non medical people to understand, explained clearly and thoroughly and even repeating things so we didn't miss anything. Thank you very much. Wish I had of found this earlier.
No Problem... ACTH is a tropic to the adrenal gland so even though potassium stimulates the zona glomulosa, too much ACTH will cause it to make more aldosterone. Additionally, high quanities of cortisol with cross-react with aldosterone receptors since they are both steriod molecules. This is what gives you the aldosterone effects of high ACTH.
I am so sorry, but you described Z glomerulosa (aldosterone secretion) not affected by ACTH levels and then when describing Cushing's disease (not syndrome) you say high ACTH will cause low K+, H+, high Na - signs of high Aldosterone secretion. How is that possible?
Hi and thanks for a very informative video! I wonder about Cortisol. If you suffer from adrenal fatigue after having had Graves disease, and thereby major anxiety (at its worst in the morning and best at night) and fatigue, is cortisol the friend or foe? And how does one recover from this? Only thing I know of is to ingest adrenal gland powder, in swedish binjureextrakt. (Not sure about the translation but a powder or pill that contains extract from animal adrenal gland.) Do you know how long it takes to recover from adrenal fatigue?
+Vixinaful - I'm sorry you have not received an answer to your question after all this time. I don't have an answer either (I also have AF), but I would like to share an AMAZING Facebook group with you called "Adrenal Fatigue Recovery". I just joined the other day and all I can say is WOW WOW WOW!!! The information within that group is astounding! I have been reading nearly non-stop for the past two days; I can't seem to pull myself away from it! I have never seen so many people who share the same problems I have...to a T. If you join the group I guarantee you will find the answers you seek. The people there are awesome! Very knowledgeable and ready to help with advice or just a listening, supportive ear. It's so nice to be in a place where people "get it" and totally understand me. It's the best group I've ever belonged to, feels like one big supportive family. Hope to see you there! :)
You have said in the video that aldostetone is not regulated by ACTH so why levels of aldostetone are increasing in Cushing syndrome or Cushing disease since they happen because of administration of pharmacologic doses of CORTISOL or production of high levels of ACTH by pituitary gland.
Hi Dr Seheult. Great video. Just wanted to point that at 7:38 you say that the only source of androgen in females in the adrenal cortex. That's not true. Up to 25% of testosterone is normally synthesized by the ovaries in females. Thanks again.
I found out when i was 16 my mom was devistated but i knew everything would be ok. I have to take medicine every day for the rest of my life it sucks but having a sore chest is natural thankfully all is well just that i look like a child even though im 18 hehe but thankfully god blessed me in a time where there is medicine for my condition
In Chinese medicine and meditation, this is referred to as the second gate or the Chia Chi. It is one of the major gates in the Microcosmic Orbit and its significance is confirmed by Western Medicine as it impacts so many physiological functions.
In cushings disease, I understand that glucose and testosterone levels rise due to increased ACTH but why would aldosterone be oversecreted as well if after some time potassium levels would be low?? wouldn't low potassium levels stop the secretion of aldosterone??
I'm watching this for the second time and I think that your presentation is great and very detailed! However I wonder - what about when someone has high ACTH but low Sodium and low blood pressure, like I do? What's that then??? :)
![DDG & G Herbo - Nosey [Official Video]](http://i.ytimg.com/vi/I9Ra0Zc2NlQ/mqdefault.jpg)
I really appreciate the speed with which you present your material. Thank you
Thank you so much for your clear and concise explanations. You make these concepts so much easier to grasp. Please keep them coming! :)
best lecture I found so far...
superb explaination......
These videos are fantastic! I'm studying for the NCLEX exam, and these videos are the best I've seen! Thank you!!
Melanie Caird Good to hear- best of luck on your exam
Not even a med student, but this stuff is generally interesting, it might sound stupid but it would also be cool to see some dummed down videos that anyone could understand
a very brief and complete explanation thank you
Thank you, I was gonna read my notes, but this made it so much easier, great vids!
Mike Rider good to hear- thanks for the comment
See the whole series at www.medcram.com along with other top quality videos including reviews in pulmonary, cardiology, infectious disease, and hematology!
Thank you ❤️
Brilliant!! Kudos to you.
Thank u so much
You're welcome!
very helpful
This helps a ton!
John Shaffer good to hear. thanks for the comment
Thank you!
thank you so freakin much .... this viedo helped me alot
So what if a person has one adrenal gland, and the other had been taken away with a partial nephrectomy?
just i have one qus, for cushing syndrome there is no influence on zg just on zf and zr, so i think the aldosterone level will be normal since it stimulated by high K not by acth. thanks for all the effort
I have the same question, awaiting response from MedCram
What do you do when your adrenal glands are overstimulated?
Thank you so much! But is it only K+ which controls aldosterone secretion? What about Angiotensin ll?
When Blood pressure decrease or hypokalimia that stimuli Renin_ angiotensin system in kidney to secret Renin that convert to angiotensin 2 to affect adrinal cortex and produce aldosterone
@@لاإلهالاالله-و6ح bbbbvvvccxxxsaàaafgjkpllllllklokjjjhjjjjjjjj
Greaaaat lecture .. thank you 👍🏻
Hello and thank you. I have had a brain tumor removed, most of it. I can't stay awake much. I was looking around and was wondering if what could cause the tumor is the lack of cortex or the Adrenal Gland itself not feeding me enough cortex. Also is there anyway to work on the Adrenal Gland and help it out.. Thank you
Nice, presentation but in Addison disease there is metabolic alkalosis not acidosis!!
In addisons disease metabolic acidosis occurs, as H+ secretion decrease
It causes metabolic acidosis with normal anion gap, and it is called as Renal Tubular Acidosis type 4
Couldn't you write more clearly?! This is counter to what you advertise...
Hi This is the first time I actually understood Addison's Disease in which I've had for 14 years. It was absolutely fantastic. Easy for non medical people to understand, explained clearly and thoroughly and even repeating things so we didn't miss anything. Thank you very much. Wish I had of found this earlier.
Thanks so much for the feedback. Glad the video was helpful!
I remember it as "GO, FOREST, RUN!"
I remember as gfr(glomerular filtration rate) also realted to kidney
Both are cool🤣
@@ayeshajahan1291 thanks! I just always think, Forrest must of had alot of ADRENALINE to run that fast! Lol
@@katierellah5366 yeah whenever u hear Forrest Gump, running is the first thing that comes to mind 😂
As a point of note, the ovaries do secrete some androgens, but the adrenal converts most of it into a usable form.
No Problem... ACTH is a tropic to the adrenal gland so even though potassium stimulates the zona glomulosa, too much ACTH will cause it to make more aldosterone. Additionally, high quanities of cortisol with cross-react with aldosterone receptors since they are both steriod molecules. This is what gives you the aldosterone effects of high ACTH.
I am so sorry, but you described Z glomerulosa (aldosterone secretion) not affected by ACTH levels and then when describing Cushing's disease (not syndrome) you say high ACTH will cause low K+, H+, high Na - signs of high Aldosterone secretion. How is that possible?
ACTH is necessary for aldosterone secretion but has little effect in controlling the rate of secretion.
Very good. Thank you
Are you referring to Cushing's Disease (and not Addison's)?
It's really useful for us sir thank u
Thank you so much. I am preparing for the steps & this was very helpful.
+Rahul Dabhi Thank you- best wishes with your exams
You Rock! This was great! Seriously awesome explanations and the diagrams made it all stick!
Martine Gaetan Good to hear- thanks for the feedback
Thank you very much!
Anyone get here because they gained weight and want to lower their cortisol? 🙋♀️
Your the best - one of the greatest clinical lecturers on RUclips! You support me through your content. Keep up the great work, Medcram!
Oooo9
Thanks alot this will going to help me in my exam 🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹
Where is the 2nd video?
The description says this is 1 of 2.
Hi and thanks for a very informative video!
I wonder about Cortisol. If you suffer from adrenal fatigue after having had Graves disease, and thereby major anxiety (at its worst in the morning and best at night) and fatigue, is cortisol the friend or foe? And how does one recover from this? Only thing I know of is to ingest adrenal gland powder, in swedish binjureextrakt. (Not sure about the translation but a powder or pill that contains extract from animal adrenal gland.) Do you know how long it takes to recover from adrenal fatigue?
+Vixinaful - I'm sorry you have not received an answer to your question after all this time. I don't have an answer either (I also have AF), but I would like to share an AMAZING Facebook group with you called "Adrenal Fatigue Recovery". I just joined the other day and all I can say is WOW WOW WOW!!! The information within that group is astounding! I have been reading nearly non-stop for the past two days; I can't seem to pull myself away from it! I have never seen so many people who share the same problems I have...to a T. If you join the group I guarantee you will find the answers you seek. The people there are awesome! Very knowledgeable and ready to help with advice or just a listening, supportive ear. It's so nice to be in a place where people "get it" and totally understand me. It's the best group I've ever belonged to, feels like one big supportive family. Hope to see you there! :)
*****
Thank you soo so much. I'll check it out straight away! :)
Thank you that was very well explained.
I just want to hug you! thank you so much :D
Great video.
You have said in the video that aldostetone is not regulated by ACTH so why levels of aldostetone are increasing in Cushing syndrome or Cushing disease since they happen because of administration of pharmacologic doses of CORTISOL or production of high levels of ACTH by pituitary gland.
addisons is adrenal insufficieny = less aldosterone = less K+ and H+ secreted = more H+ in blood = metabolic acidosis
what
Hi Dr Seheult. Great video. Just wanted to point that at 7:38 you say that the only source of androgen in females in the adrenal cortex. That's not true. Up to 25% of testosterone is normally synthesized by the ovaries in females. Thanks again.
I found out when i was 16 my mom was devistated but i knew everything would be ok. I have to take medicine every day for the rest of my life it sucks but having a sore chest is natural thankfully all is well just that i look like a child even though im 18 hehe but thankfully god blessed me in a time where there is medicine for my condition
I don't think z. Glomerulosa relies soley on positive or negative feedback stimulus, doesn't ACTH play a role?
Great video, so clear! Thank you
Please explain the link between increased ACTH and increased aldosterone. The last part straight-out confuses me.
So helpful, simple yet detailed, and interesting! Thanks so much!
Thyroidgland
Hi
All I could say is thank you very much
Thank you for explaining this!! Do you have a Medcram website where one can purchase additional info? Thanks in advance for your response.
Are you familiar with the pupillary reflex test to check adrenal function? If so, can you confirm whether it's a valid test?
Now I totally got the picture, thanks.
Thank u so much sir. When i studied pharmacy these were difficult for me
Your brilliance made everything easy.luv ur coaching
Your lectures are AMAZING , Thank you so much for sharing it, iam waiting for more lectures...
Thanks for the video.Can I ask why PCOS wasn't mentioned when dysfunction with the glands was covered?
thank you for understandable explanation, very helpful!!! pls do more video of pathophysiology of different diseases.
This is very helpful, thanks alot!
This is what I wanted
I am surprised that the RAAS system was not even mentioned when you talked about what stimulates aldosterone release!!
i have addison disease so this is obviously very interesting to me. thank you for making this available to the public.
what is adrnal glands abscess ?
How about Losing weight of Gaining weight ?? witch one is the reason of getting fat or getting skinny all of sudden ? Thank you.
MidoTV Adventure That's to do with the Thyroid Hormones (hyper + hypothyroidism)
Brilliant 5*!
#adrenochrome
Could you explain the difference between dopamine, serotonin, adrenaline, and endorphins? Thanks
Transcend Your Limits Thanks for the suggestion. We'll keep those hormones and neurotransmitters in mind for future lecture topics
In Chinese medicine and meditation, this is referred to as the second gate or the Chia Chi. It is one of the major gates in the Microcosmic Orbit and its significance is confirmed by Western Medicine as it impacts so many physiological functions.
In cushings disease, I understand that glucose and testosterone levels rise due to increased ACTH but why would aldosterone be oversecreted as well if after some time potassium levels would be low?? wouldn't low potassium levels stop the secretion of aldosterone??
I like u did by writing R instead of F,... active learning
Can you explain how in addison's disease there is an increase in aldosterone but only ACTH that's increasing? Thanks
Awesome video, really helpful! Thank you very much
adrenal gland
Thank you
Thanks for a very useful presentation 👍👍👍
Where is the second video on the adrenal cortex?
Medcram.com
sound like primary adrenal failure (addison's disease). this could make you tan as well. Should get that checked out soon.
I'm watching this for the second time and I think that your presentation is great and very detailed!
However I wonder - what about when someone has high ACTH but low Sodium and low blood pressure, like I do?
What's that then??? :)
You said for women, their only source of androgens are from the renal cortex? I believe ovaries also make some testosterone in the theca cells.
chienn77 that is true. But the predominant source is the adrenal.
My glaaaand 😭
Osam
This easy to understand information has proven very useful to my anatomy and physiology coursework. Thank you, thumbs up.
Interested in hearing about Vit D synthesis, extra renal synthesis of such, and functions of VDR.
+Jamie Riffle Thanks for the topic suggestions
I BADLY NEED THIS ONE!! THANK YOU FOR SHARING YOUR ABUNDANCE OF KNOWLEDGE. MORE POWER TO YOU! :)
+May Elisan Thank you for the feedback. More videos coming soon
so much helpful ✌️
Thank you so much!
Thank you so much for your work. It is really helpful
Can You Please Give a Lecture about How to activate Andrenaline
You're better than my professor!
thanks from Czech Republic student. btw you have very nice voice :)
Hmmmm thanks for that tip I will check them again in 2 months.
Where is the second lecture?
Question How do we Activate our Andrenalines ?
Ya Cushing's Disease sorry. thanks
very nice..explanation...
Aman Kumar Mishra
Looks like illuminati
Thanks. Wonderful explanation!!
Thank you, Thank you, Thank you
Excellent video!
than you very much
brilliant. thank you 3