Hi Dr. Griggs, tripple positive, stage 1, lesion 1cm. Is luminal B? Another question why most of the data is only showing survival in 5 year period? After that the possibility of reoccurrence decrease? Thank you for your help! You are amazing explaining us about this disease.
Thanks for the question. Much of the data in other cancers is only to 5 years. In breast cancer, we have 10 to 30 years of data combined from hundreds of thousands of women. With newer therapies, we have to wait a very long time to get results of course, so often, 5-year outcomes will be presented. It's really difficult to follow the same people for more than 5 years in many cases. People move and don't share their address or they switch doctors, etc. This is the challenge we face with the fragmented health system that many of us experience.
Hello Dr. Gibbs, My mom is using Palbociclib, can we know through blood test that cancer have reduced to zero? Anyway great videos and loved it as aleays.
@@yerbba cancer creates anemia, so if haemoglobin becomes normal range ,does it mean cancer is gone? If there are no scans, then when does doc conclude to stop palbociclib? Thanks for your reply doc.
You might have talked about this but I was dx ER positive PR Borderline and HER negative..what does it mean to be PR Borderline .my treatment was chemotherapy, radiation with booster and 5 yrs of Aromasin.. also dx was Stage 3 Lobular CA..thank you..your videos are very helpful..
"Borderline" means that it was positive but not strongly positive enough to call it positive. Breast cancers with 1-10% of cells expressing progesterone receptors are considered borderline PR-positive. The endocrine responsiveness and prognosis of borderline PR breast cancers are not as clear as those with higher PR expression levels. All other things being equal, borderline hormone receptor-positive breast cancers generally have a prognosis between that of hormone receptor-negative and strongly positive tumors.
This is a great helpful information dear dr Griggs, my question is er 95% progesterone 65% k67 is about 20, in metestatic er pr positive her2 negative bc cancer, is it luminal A or luminal B ? Please Thank you❤
Thank you for your question! Based on the info you provided, it's a little difficult to tell. The relatively high Ki67 score is consistent with a Luminal B cancer. Determining treatment options can be challenging without insight into the unique characteristics of your tumor, any pre-existing conditions, and your overall health. If you're in the U.S., visit www.yerbba.com to get your personalized Yerbba Report. This resource offers personalized treatment options and detailed insights to help you navigate treatment decisions with confidence.
Invasive lobular breast carcinoma, multicentric, moderately differentiated (G2), with positive estrogen and progesterone receptors, ki 67-20%, Her 2 negative(1+)/Her2-low What would be the optimal treatment? Thank you
With invasive lobular carcinoma that’s ER/PR positive and HER2-low, there are several potential treatment approaches. Optimal treatment depends on the full context of your health and specific tumor biology, so without being part of your medical team, it’s difficult to offer a recommendation. However, if you’d like a comprehensive view of your diagnosis and personalized treatment options, visit Yerbba.com to receive your personalized Yerbba Report. Your report provides insights and treatment possibilities based on your tumor’s unique biology and is continuously updated, helping you understand the full scope of your diagnosis and make informed decisions.
With invasive lobular carcinoma that’s ER/PR positive and HER2-low, there are several potential treatment approaches. Optimal treatment depends on the full context of your health and specific tumor biology, so without being part of your medical team, it’s difficult to offer a recommendation. However, if you’d like a comprehensive view of your diagnosis and personalized treatment options, visit Yerbba.com to receive your personalized Yerbba Report. Your report provides insights and treatment possibilities based on your tumor’s unique biology and is continuously updated, helping you understand the full scope of your diagnosis and make informed decisions.
Cribriform breast cancer is a rare type of breast cancer. Under a microscope, the cancer cells form a pattern that looks like Swiss cheese or a sieve, with small holes or spaces within groups of cells. This unique appearance gives it the name "cribriform." Cribriform cancer grow slowly and have a good prognosis. Surgery is usually the first treatment, which may be followed by radiation therapy and/or hormone therapy. Chemotherapy is not typically used for this type of breast cancer.
Great question! Luminal HER2 cancers are typically classified as luminal B due to their higher proliferation rate and HER2 expression. It’s always worth confirming with your oncologist for specifics about your case.
With ER 95%, PR 95%, Ki-67 at 40%, and HER2 negative, it appears to be a highly hormone receptor-positive cancer with a high proliferation rate. Determining treatment options can be challenging without insight into other characteristics of your tumor, the stage, any pre-existing conditions, and your overall health. For personalized treatment options tailored to your specific needs, we recommend visiting www.yerbba.com to access your personalized Yerbba Report.
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Hi Dr. Griggs, tripple positive, stage 1, lesion 1cm. Is luminal B? Another question why most of the data is only showing survival in 5 year period? After that the possibility of reoccurrence decrease? Thank you for your help! You are amazing explaining us about this disease.
Thanks for the question. Much of the data in other cancers is only to 5 years. In breast cancer, we have 10 to 30 years of data combined from hundreds of thousands of women. With newer therapies, we have to wait a very long time to get results of course, so often, 5-year outcomes will be presented. It's really difficult to follow the same people for more than 5 years in many cases. People move and don't share their address or they switch doctors, etc. This is the challenge we face with the fragmented health system that many of us experience.
Have you done a video on Lobular breast cancer? Info seems limited.
Check out our video on lobular breast cancer here: ruclips.net/video/0IcNKZ7ccpw/видео.html
Would it be possible to do a video on ki-67.
Yes, thank you for the suggestion.
Hello Dr. Gibbs, My mom is using Palbociclib, can we know through blood test that cancer have reduced to zero?
Anyway great videos and loved it as aleays.
Great question. No, there is no blood test or scan that can say all the cancer has been removed and that there is no cancer in the body.
@@yerbba cancer creates anemia, so if haemoglobin becomes normal range ,does it mean cancer is gone? If there are no scans, then when does doc conclude to stop palbociclib?
Thanks for your reply doc.
You might have talked about this but I was dx ER positive PR Borderline and HER negative..what does it mean to be PR Borderline .my treatment was chemotherapy, radiation with booster and 5 yrs of Aromasin.. also dx was Stage 3 Lobular CA..thank you..your videos are very helpful..
"Borderline" means that it was positive but not strongly positive enough to call it positive. Breast cancers with 1-10% of cells expressing progesterone receptors are considered borderline PR-positive. The endocrine responsiveness and prognosis of borderline PR breast cancers are not as clear as those with higher PR expression levels. All other things being equal, borderline hormone receptor-positive breast cancers generally have a prognosis between that of hormone receptor-negative and strongly positive tumors.
This is a great helpful information dear dr Griggs, my question is er 95% progesterone 65% k67 is about 20, in metestatic er pr positive her2 negative bc cancer, is it luminal A or luminal B ? Please
Thank you❤
Thank you for your question! Based on the info you provided, it's a little difficult to tell. The relatively high Ki67 score is consistent with a Luminal B cancer. Determining treatment options can be challenging without insight into the unique characteristics of your tumor, any pre-existing conditions, and your overall health. If you're in the U.S., visit www.yerbba.com to get your personalized Yerbba Report. This resource offers personalized treatment options and detailed insights to help you navigate treatment decisions with confidence.
Thank you Doctor ❤
Er 100%+,PR (-) and her2(-) lymph node nagetive please guide me which type of this luminal A or B?
This may be either luminal A or B. The negative PR makes it more likely to be luminal B, but having the Ki67 would be helpful.
Invasive lobular breast carcinoma, multicentric, moderately differentiated (G2), with positive estrogen and progesterone receptors, ki 67-20%, Her 2 negative(1+)/Her2-low
What would be the optimal treatment? Thank you
With invasive lobular carcinoma that’s ER/PR positive and HER2-low, there are several potential treatment approaches. Optimal treatment depends on the full context of your health and specific tumor biology, so without being part of your medical team, it’s difficult to offer a recommendation. However, if you’d like a comprehensive view of your diagnosis and personalized treatment options, visit Yerbba.com to receive your personalized Yerbba Report. Your report provides insights and treatment possibilities based on your tumor’s unique biology and is continuously updated, helping you understand the full scope of your diagnosis and make informed decisions.
With invasive lobular carcinoma that’s ER/PR positive and HER2-low, there are several potential treatment approaches. Optimal treatment depends on the full context of your health and specific tumor biology, so without being part of your medical team, it’s difficult to offer a recommendation. However, if you’d like a comprehensive view of your diagnosis and personalized treatment options, visit Yerbba.com to receive your personalized Yerbba Report. Your report provides insights and treatment possibilities based on your tumor’s unique biology and is continuously updated, helping you understand the full scope of your diagnosis and make informed decisions.
I was diagnosed with luminal A BC. The pathology report says the tumor is cribriform. What does that mean?
Cribriform breast cancer is a rare type of breast cancer. Under a microscope, the cancer cells form a pattern that looks like Swiss cheese or a sieve, with small holes or spaces within groups of cells. This unique appearance gives it the name "cribriform." Cribriform cancer grow slowly and have a good prognosis. Surgery is usually the first treatment, which may be followed by radiation therapy and/or hormone therapy. Chemotherapy is not typically used for this type of breast cancer.
@@yerbba Thank you. I find your channel very helpful.
Thank you
Thank you for watching!
Is luminal HER2 always considered luminal B cancer?
Great question! Luminal HER2 cancers are typically classified as luminal B due to their higher proliferation rate and HER2 expression. It’s always worth confirming with your oncologist for specifics about your case.
pr 95%er95% k67 40% here negative?.Please.Thank you so much dr❤
With ER 95%, PR 95%, Ki-67 at 40%, and HER2 negative, it appears to be a highly hormone receptor-positive cancer with a high proliferation rate. Determining treatment options can be challenging without insight into other characteristics of your tumor, the stage, any pre-existing conditions, and your overall health. For personalized treatment options tailored to your specific needs, we recommend visiting www.yerbba.com to access your personalized Yerbba Report.