I've always liked Dr. Mike's stuff because he's very clear about, "This part gets you 90% of the benefit, this other part works, but for most people isn't worth the effort." I'm glad to see other experts confirm he's right on the science.
This is pretty much where I'm at. I've followed Dr. Mike for close to 10 years, and the majority of his advice will be have him saying something to the effect of "This should work most of the time for most people" and he makes that clear, he doesn't typically deal with any absolutes. And the majority of his advice, even at worse while not necessarily "good" advice, it isn't "bad" advice
Only after Gregg Doucette responds to the response on Zack Tealander's channel about the response from the Doucette vs Israetel debate on Mark Bell's channel. /s
This was great. Love this format. Dr Mike would be a great entertaining guest and would take any pushback quite graciously. He is a PhD but be prepared for extremely high energy.
I’m personally very interested in learning more about longevity and am already a huge Dr. Mike fan. I’m glad I was able to find this ‘reacts’ video and your channel! This was great!
Have you watched his original video? He’s elaborated on the point to a degree that I’m 99% confident it’s not a joke. But, he does have layers of dry humor so who knows.
Loving the reaction videos, keep it up! I think there is a massive hunger for unbiased, thoughtful, and reputable information (especially in response to the sea of garbage that is already out there) about longevity and aging.
What I liked most is his comment that “at least that aligns with my opinions” rather that flat out saying this is right and/or wrong. It shows an appropriate amount of humility.
As a biochemist (just a BS tho), I'm glad that the health and fitness space is becoming more scientific in nature. There's a level of bluntness and humility that most people in science have to develop (typically via suffering in academia) to assert a more widely accepted hypothesis or to acknowledge when they're out of their depth, and it makes the transfer of knowledge *so* much more efficient and easy to understand. It makes pursuing my own fitness goals more intellectually stimulating, which personally really ups my motivation and enjoyment of the process. Really appreciate that this was on display in the critique! Curious to do some reading on NMN and see what that's all about.
Man that "level of bluntness" can really bite you in the ass out in civilian life when you accidentally expose it to normal people who usually haven't had to develop the necessary humility to match it..
Well if you want Biochemistry check out Sara Pughs YT. Health Science can never be as science based as the name suggests. This is because your cant run extended tests with adequate Controls. Professor Bart Kay has covered all that on his main YT channel. He also covers the flaws of what Beliefs people hold, which have and always will be wrong. Just because the Institutes themselves are utterly corrupted. Harvard is one for example. Harry Serpanos is also a self-taught good source of what nobody covers at length or is able to piece together.
yeah there are a lot of people preaching the benefits of NMN for the NAD cycle. Not sure I understand the hate on that one. It is a little pricey, but Bryan Johnson and Jeffrey Gladden support it and I believe the NOVOS supplement and Nuchido have it in. It just gives more NAD to help make ATP is my understanding.
In the past, 'reaction' videos seemed pointless and infuriating when people were just reacting to e.g cat videos... But to hear the opinions and thoughts and critique and analysis from one scientist to another really holds a lot of value and benefit! Enjoyed the format, would love more and similar content, helps to see blindspots in my own thinking, and gain a more reasonable view on the world - thanks for uploading!
It's like reading a discussion under a scientific blog/quora/facebook/whatever post, except the people commenting actually know what they're talking about
the problem with this format is that when someone mis-interpret's a statement, there isn't the opportunity for clarification which leads to bad communication of ideas
That’s a good observation. We reacted to some tweets by Dr. Charles Brenner, to which he replied… Which led to us having him on the podcast (episode comes out Tuesday). Taking the conversation from Twitter/react content to in person was a big improvement.
I’m torn on this! I’m a pretty big fan of Mike and I’ve heard him mention that 2040 comment a few times. He seems genuine about it, but you’re right about his deep sarcasm. Thank you! Glad you enjoyed the video. - Nick
@optispan I did enjoy it. Thank you! Maybe he will see some of these comments and weigh in on it. It would be interesting to hear his reply. I'll be watching for more vids! Nice channel.
@@BrickhouseFitnessNutrition Dr.Mike Crazy about 2040 watch Doctor Mike podcast he going all in. and to be fair we don't know yet maybe he right? I hope I stay alive in 2040 to prove that haha.
I personally don't like using "doctor" for anyone other than medical doctors. It's confusing for people speaking about health but who have a PhD in math or science, and don't get me started on nurse practitioners with a DNP (doctorate in nursing) who want to be called doctor.
I don't think he meant that decreasing the body size makes you live longer because of the link of with-in species size and longevity, but because in getting smaller while maintaining lean body mass, you will have to restrict calories which has indeed been shown to be a reliable strategy of longevity (in every model organism studied and there does exist evidence for humans as well).
Also, the risk that having high weight has on heart health regardless of whether that is muscle or fat. Moderate weight with high muscle mass probably safe. Moderate weight with high fat, probably not. High weight, just not. Doubly worse if high weight high fat.
I think they are fun. I would watch more so long as they stay lighthearted and respectful. Too many influencers are toxic when they critique others and it’s exhausting. Lane Norton is a good example of this. Just have fun with it and pick your spots carefully. Dr Mike was a great pick because he so funny. I’m sure he would enjoy this critique. Love this channel.
Thanks smart people. Old truck driver here. Lifting weights and trying not to eat junk. Nice to hear educated people discuss the topic. How about brain health? Is things like learning a new language good for extending your healthy years?
I wish Mike would stop saying on multiple podcasts that we'll have solved all diseases in 16yrs. Hell, I'm still waiting on my flying car we were promised by the year 2000. He was on the medical Dr Mike's show and said that and medical Dr Mike said it won't happen and explained drug approval and that 1 drug often interferes with others and causes other problems so even if a drug could do that, not everyone could take it. (I was made diabetic by a mood medication so I get it.)
Also who will be disease free in 20 years? We barely include women in medical studies. It takes an average of 7-10 YEARS for a woman to be diagnosed with endometriosis which can a be debilitating condition that effects a huge percentage of women…… we can barely detect a heart attack inn women and so on and so on…. We are NO WHERE near eliminating “disease” and if we are it is only in men
Thank you for the suggestion! I added it to our master doc of episode ideas. We do Omega checks at Optispan and have our recommendations of omega 3 - omega 6 ratios. So I think there’s two points we can dig into. 1. Seed oils/Omega-6s 2. Omega ratios
I look at the healthy aging movement as a "wide tent" movement. It can accommodate a wide array of views ranging from super-optimism to deep skepticism. People with these views share some ideas/perspectives in common--and that allows them to work together on common goals (for laypeople = advocacy and funding). The only individuals who wouldn't fit in are cynics (who believe either that nothing at all can ever be done to slow/reverse aging or that nothing should be done...).
Watch the original RP video. Mike goes into great detail about “Longevity Escape Velocity” and from what I’ve seen he genuinely thinks if you can make it to ~ 2040 then you’ll be fine. But he does have layers of human and it may have gone over our heads!
dr mike regards himself as highly optimistic. you can see this in other podcasts as well. he really believes that progress, be it in AI or in medicine, will only exponentially improve more and more and be able to achieve results that sound absurd today.
Dr Mike isn't joking about that. I've listened to him rant about it ad nauseam and he does believe we will reach longevity escape velocity in the 2040s
No, 2040 things was absolutely not a joke. He had a really good discussion about it on Dr. Mike’s podcast, he believes science will make insane leaps in the next few years.
Maybe have a dislogue with "The Other Dr. Mike" ftom NY who deals with middle and lower class clients and the truuths of their lives...multiple jobs, no health insurance, few health education opportunites, lack of childcare. While i appreciate the mission to bring health to the masses, i don't know if concierge health care can make a dent for the population that needs it most.
I recommend watching Dr. Mikes full video on the RP channel. He goes into that in more detail on this subject. I’m also surprised in how he is in scientific breakthroughs the next 15~20 years. But hey, let’s hope he’s right!
@@nicholasarapis Did that already - he is one of my favorites! I've visited Harvard Medical to speak about aging biology progress last year (for my own channel) and with the current levels of funding, interest (and misinformation) we'd be very lucky to see something this century...
To be fair, although I don’t have a PhD in anything related, I could have told you to stay lean and strong and not eat garbage. This is just common sense at this point.
Bro got peer reviewed XD. We need more of this. We need more high quality Sci Comm and discourse in the health and fitness space. We've had enough of bro science. Love the high quality educational and informational content of both of you put out for free. I look forward to joining you after finishing my degree.
I'm going to join the consensus here. Periodic videos in this format are great and Dr Mike is one of the funniest guys on YT. But I'll add a question that I would love to see Matt address one day: what does think about the idea constantly repeated by De Grey that caloric restriction mimetics like Rapamycin are not very effective for long-lived species like ours because evolution had no reason to adopt mechanisms to combat long famines (as opposed to short ones)? He keeps repeating this idea to his broad audience in the longevity space but I've never seen it addressed head-on by Matt in any of his many Rapamycin videos. Thanks.
afaic Dr.Mikes opinion on the future is based on A.I solving almost all problems in all fields, with it soon becoming far more capable than humans. Having A.I going from non existant 5 years ago, to a major tool in almost all sectors, while still improving rapidly is probably his basis on all the exponential growth.
Great video, guys. I'm happy I stumbled upon this. Any idea why he singled out FRESH fruits and veggies as being ideal? Wouldn't frozen be just as good?
I think Mike's comment re science will solve aging by 2040 was mostly a joke. If you watch a lot of Mike's talks half of what he says is either sarcasm or a joke. He just can't help himself
People have been claiming for centuries that a cure for aging was "just around the corner." Not an intelligent comment by a so called intelligent expert...
I don’t think so, Dr Mike has thrown 2040 out several times in his videos and seems to very genuinely believe that we will continually see exponential growth in computing power and unimaginably powerful ai will soon exist that solves every problem humanity has or could have
Hi Matt and team, could you give us some thoughts on GlyNAC ? A couple of studies from Houston seem compelling with regard to old age function, if not on longevity per se.
What are your thoughts on rosmarinic acid? According to the study- Plant and fungal products that extend lifespan in Caenorhabditis elegans, it increased the life span of nematodes by 63 percent.
If Dr. Mike does believe in humanity conquering longevity by 2040, it's probably just a defense mechanism to justify his steroid use. He's willing to accept the fact that steroid use might shorten his life, but believing in a fast approaching cure-all gives him at least some hope that he might not have to pay the piper. It's a mild form of denial of his fear of dying young.
Soooo Ive just heard about this thing called TMG and then remembered that you guys had a negative response to NMN or something like that which was suggested to be used alongside TMG . . . .can you guys give me the correct story, is TMG good for you or is it bad like what I think you say NMN is and why? thank you - feel free to just point me to a video if you already discussed TMG somewhere.
@@glassman3333exactly. I also understand where he's coming from. I'm not an IT expert, but read a book about AI. If we look at the game of chess, we've been playing this game for hundreds of years. We gathered knowledge about it, wrote books about it and some mastered the game by thousands of hours of practice. Then we build chess computers with rule based software. "if opponent does this, then computer does this". Those computers were pretty good, to the point they could beat chess masters. Then with AI we build a new sort of chess computer, not rule based anymore. It looked at thousands of games between chess masters and learned the patterns in their strategies. This AI chess computer was so good it beat the rule based computer 100 to 0 and also beat chess masters 100 to 0. You now have an AI computer that is way better than what we as humans gathered in hundreds of years. Now the scary part is, someone made a 2nd AI chess computer. This time the computer didn't learn patterns from watching humans play. It only knew the rule book of chess and played thousands and thousands and thousands of games against itself, learning new patterns, finding out what works and what doesn't, to the point that it now created its own never before seen strategies. This AI chess computer version 2 now learned chess with basically no human intervention, besides a human inputting the rule book of chess in the beginning. This version 2 computer played against the version 1 AI computer (the one who learned patterns from seeing masters play) and beat that computer 100-0 in 100 games. So just as an example of how AI learned itself to play chess in a few hours (by simulating those 1000s of games), and got to a level sooo much higher than anything we as humans could reach after hundreds of years of playing this game. We are used to a certain pace in developping in science, but one new AI application can disrupt everything we thought we knew about how long it takes to develop in certain areas. One very interesting topic in that regard is DNA research. It's extremely complicated to find out which part of the DNA is which gene. It used to take multiple PHD students multiple years of their time to find 1 part gene. At the pace we were going before AI it would have probably taken us multiple centuries to find out all we want to know. Not to mention the cost to fund those PhD researchers. AI now started doing this research for us and every part it learns to solve, makes it better, faster, more efficient, to the point that it might figure out the entire function of all genes in a matter of a few years. This is huge in researching causes of disease, and thus in solving the diseases. However at the same time I'm not sure if we will be able to keep up with all this new knowledge and if we can really market new medicines very fast, given FDA protocols and so on.
PS. It seems that partial reprogramming is moving much faster (research and development-wise) than many other geroscience-related sub-fields. Is that a fair assessment?
With regards to celluar re-programming: What would happen if it could be achieved through natural compounds ? Then it wouldn't need FDA approval ,or could you just go to that secret island that isn't secret and have it done there in 2030 ? Since its to governed by the FDA.
Saying that 240 lbs is not optimal, I understand the rational. However, at what height? Doesn't height come into plain? To shorter people live longer? How about a 6'1 person at 240 vs. a 6'5" person at 240. If I was 6'5" or taller, I would not want to be under 200 lbs. Why no mention of how height factors into the equation. I'd love to know what is optimal for my height at 6'3".
You know what really helps longevity and health? NOT taking huge amount of steroids for the single purpose of prancing in a g strings for the enjoyment of some people. Addicts arent people to take your health cues from.
For me it's always been high carbs and enough protein and small amounts of fat. What's the deal with MNM? I feel like I've read a lot it longevity and MNM. I think I've heard people say it significantly increases life span but that seems a bit optimistic.
Could you expand on what you mean by growth signals during development and smaller body size? Does smaller body size just refer to shorter individuals or is it a weight based thing referring to people with skinnier frames?
Bodybuilding mentality is not a perspective that helps most people. It is by design an extreme approach and its focus is not based on health. Bodybuilding has an aesthetic goal and almost every thing else is sacrificed. BTW the steroids he takes pretty much eliminates him as a good mentor.
You were supposed to start beef! Where’s the DrAmA!! Blood for the blood god! Jk yeah, he’s legit. This was great. I like this idea of “peer reviewing RUclips videos”.
This health/ exercise space is definitely levelling up. Next up, Mike critiques the critique. Otherwise known as a response 😅
can't wait lol.. gonna be awesome!
Then they do a diss track and then a charity boxing event
Doc with a personality. Would be fun to hear his response to the response of his video.
I've always liked Dr. Mike's stuff because he's very clear about, "This part gets you 90% of the benefit, this other part works, but for most people isn't worth the effort." I'm glad to see other experts confirm he's right on the science.
This is pretty much where I'm at. I've followed Dr. Mike for close to 10 years, and the majority of his advice will be have him saying something to the effect of "This should work most of the time for most people" and he makes that clear, he doesn't typically deal with any absolutes.
And the majority of his advice, even at worse while not necessarily "good" advice, it isn't "bad" advice
I'm going to need to see Eric Bugenhagen's reaction to Jeff Nippard's reaction to this
I am going to watch Jason Blaha's response to this
Only after Gregg Doucette responds to the response on Zack Tealander's channel about the response from the Doucette vs Israetel debate on Mark Bell's channel. /s
@@LarsRyeJeppesen No way I'm watching Jason Blowhard's drivel
This was great. Love this format. Dr Mike would be a great entertaining guest and would take any pushback quite graciously. He is a PhD but be prepared for extremely high energy.
And very sweary, crude commentary.
His PhD is in sports science if memory serves. That's why he doesn't know enough about longevity.
@@againsteveryoneswill1923The sweary, crass commentary is very important before inviting Mike lol
I’m personally very interested in learning more about longevity and am already a huge Dr. Mike fan. I’m glad I was able to find this ‘reacts’ video and your channel! This was great!
We need a Dr. Mike and Dr. Matt collaboration!
Dr Mike fan to amused by the long response to his joke about just make it to 2040
Have you watched his original video? He’s elaborated on the point to a degree that I’m 99% confident it’s not a joke. But, he does have layers of dry humor so who knows.
Loving the reaction videos, keep it up! I think there is a massive hunger for unbiased, thoughtful, and reputable information (especially in response to the sea of garbage that is already out there) about longevity and aging.
Dr. Mike is a very interesting character... He packs the technical content in very smart communication folders
Haha this was great! Love Dr Mike, his style, makes me laugh every time. And his advice is generally super solid.
What I liked most is his comment that “at least that aligns with my opinions” rather that flat out saying this is right and/or wrong. It shows an appropriate amount of humility.
The more you learn the more you realise how little you actually know
I found this through being a fan of Dr Mike. You've got a new follower, loved the format and look forward to seeing the rest of your videos!
As a biochemist (just a BS tho), I'm glad that the health and fitness space is becoming more scientific in nature. There's a level of bluntness and humility that most people in science have to develop (typically via suffering in academia) to assert a more widely accepted hypothesis or to acknowledge when they're out of their depth, and it makes the transfer of knowledge *so* much more efficient and easy to understand. It makes pursuing my own fitness goals more intellectually stimulating, which personally really ups my motivation and enjoyment of the process.
Really appreciate that this was on display in the critique! Curious to do some reading on NMN and see what that's all about.
Man that "level of bluntness" can really bite you in the ass out in civilian life when you accidentally expose it to normal people who usually haven't had to develop the necessary humility to match it..
Well if you want Biochemistry check out Sara Pughs YT.
Health Science can never be as science based as the name suggests. This is because your cant run extended tests with adequate Controls. Professor Bart Kay has covered all that on his main YT channel. He also covers the flaws of what Beliefs people hold, which have and always will be wrong. Just because the Institutes themselves are utterly corrupted. Harvard is one for example.
Harry Serpanos is also a self-taught good source of what nobody covers at length or is able to piece together.
yeah there are a lot of people preaching the benefits of NMN for the NAD cycle. Not sure I understand the hate on that one. It is a little pricey, but Bryan Johnson and Jeffrey Gladden support it and I believe the NOVOS supplement and Nuchido have it in. It just gives more NAD to help make ATP is my understanding.
In the past, 'reaction' videos seemed pointless and infuriating when people were just reacting to e.g cat videos... But to hear the opinions and thoughts and critique and analysis from one scientist to another really holds a lot of value and benefit! Enjoyed the format, would love more and similar content, helps to see blindspots in my own thinking, and gain a more reasonable view on the world - thanks for uploading!
It's like reading a discussion under a scientific blog/quora/facebook/whatever post, except the people commenting actually know what they're talking about
Now Dr. Mike should react to this video
That would be a dream come true for me! Ha.
@@nicholasarapis or they should just have a conversation
@@topofthemornintoya As of now we’re only doing in person interviews. But we’d love to travel to Mike or host him in our studio!
the problem with this format is that when someone mis-interpret's a statement, there isn't the opportunity for clarification which leads to bad communication of ideas
That’s a good observation. We reacted to some tweets by Dr. Charles Brenner, to which he replied… Which led to us having him on the podcast (episode comes out Tuesday). Taking the conversation from Twitter/react content to in person was a big improvement.
His 2040 comments were sarcasm. If you watch more of his stuff you will pick up on it. He is wildly sarcastic. 😅. Fun video, thanks guys!
I’m torn on this! I’m a pretty big fan of Mike and I’ve heard him mention that 2040 comment a few times. He seems genuine about it, but you’re right about his deep sarcasm.
Thank you! Glad you enjoyed the video.
- Nick
@optispan I did enjoy it. Thank you! Maybe he will see some of these comments and weigh in on it. It would be interesting to hear his reply. I'll be watching for more vids! Nice channel.
@@BrickhouseFitnessNutrition Dr.Mike Crazy about 2040 watch Doctor Mike podcast he going all in. and to be fair we don't know yet maybe he right? I hope I stay alive in 2040 to prove that haha.
I don’t think he’s joking about 2040.
Really enjoyed this! Collab with Dr Mike, please! 👏
At last someone laugh at Mikes jokes... It must be love ❤
This is just wonderful. The new RUclips trend is for every RUclipsr to criticise other RUclipsrs! And they are all "Doctors" or "Scientists"
Thanks.
I personally don't like using "doctor" for anyone other than medical doctors. It's confusing for people speaking about health but who have a PhD in math or science, and don't get me started on nurse practitioners with a DNP (doctorate in nursing) who want to be called doctor.
Good video, and I appreciated the apparent integrity. Thank you.
Like the format. Keep it up.
Thank you! - Tara
I don't think he meant that decreasing the body size makes you live longer because of the link of with-in species size and longevity, but because in getting smaller while maintaining lean body mass, you will have to restrict calories which has indeed been shown to be a reliable strategy of longevity (in every model organism studied and there does exist evidence for humans as well).
Interesting! Here’s a video that dives deeper into body size and aging.
ruclips.net/video/Fjh6WbkZkvw/видео.htmlsi=yd9hg7O1Zs1xg3c9
Also, the risk that having high weight has on heart health regardless of whether that is muscle or fat.
Moderate weight with high muscle mass probably safe.
Moderate weight with high fat, probably not.
High weight, just not. Doubly worse if high weight high fat.
Great video, love this format
Dr. Mike was being facetious about 2040. Lol
I don’t think he’s joking about 2040.
From a young age, live a healthy life, stay lean, maintain decent muscle mass.
I think they are fun. I would watch more so long as they stay lighthearted and respectful. Too many influencers are toxic when they critique others and it’s exhausting. Lane Norton is a good example of this. Just have fun with it and pick your spots carefully. Dr Mike was a great pick because he so funny. I’m sure he would enjoy this critique. Love this channel.
Agreed! We are very cognizant of our tone and and our goal of putting out high quality content. Layne Norton is great!
Thanks smart people. Old truck driver here. Lifting weights and trying not to eat junk. Nice to hear educated people discuss the topic. How about brain health? Is things like learning a new language good for extending your healthy years?
I kinda felt left in the dark when you mentioned NMN but didn't go into detail. Enjoyed the vid very much tho!
We have full length episodes in NMN if you'd like more context.
ruclips.net/video/OgsfIUfuyqk/видео.html
Yeah, I didn’t understand that part, il check out the link
Love the format. There are far too many "experts" giving mixed advice. Helps to see them put thru Dr. Kaeberlein's BS filter
Let’s see, stay lean, exercise and eat healthy. That’s some groundbreaking stuff.
Eat plant-based, don't drink, don't smoke, don't do drugs, take a few supplements.
I wish Mike would stop saying on multiple podcasts that we'll have solved all diseases in 16yrs. Hell, I'm still waiting on my flying car we were promised by the year 2000.
He was on the medical Dr Mike's show and said that and medical Dr Mike said it won't happen and explained drug approval and that 1 drug often interferes with others and causes other problems so even if a drug could do that, not everyone could take it. (I was made diabetic by a mood medication so I get it.)
Also who will be disease free in 20 years? We barely include women in medical studies. It takes an average of 7-10 YEARS for a woman to be diagnosed with endometriosis which can a be debilitating condition that effects a huge percentage of women…… we can barely detect a heart attack inn women and so on and so on…. We are NO WHERE near eliminating “disease” and if we are it is only in men
The seed oil part was interesting. Maybe Matt could do a show on the Omega-3 / Omega-6 PUFAs and how this balance may affect longevity?
Thank you for the suggestion! I added it to our master doc of episode ideas.
We do Omega checks at Optispan and have our recommendations of omega 3 - omega 6 ratios.
So I think there’s two points we can dig into.
1. Seed oils/Omega-6s
2. Omega ratios
Yes 🙌 they’re fun. Thank you
Yes this was good. It's cool that you enjoy Dr. Mike's sense of humor
I look at the healthy aging movement as a "wide tent" movement. It can accommodate a wide array of views ranging from super-optimism to deep skepticism. People with these views share some ideas/perspectives in common--and that allows them to work together on common goals (for laypeople = advocacy and funding). The only individuals who wouldn't fit in are cynics (who believe either that nothing at all can ever be done to slow/reverse aging or that nothing should be done...).
Valid points. Dr. Mike gives great advice in general, but could certainly be wrong.
Great format. Fun and interesting.
Most underrated podcast on the internet
Thank you! Share with people who may find it helpful 💪🏼
I love both podcasts!
Thank you for your support!
Very informative. Thank you.
super annoying that they couldn't tell that the whole 2040 thing was a joke
Watch the original RP video. Mike goes into great detail about “Longevity Escape Velocity” and from what I’ve seen he genuinely thinks if you can make it to ~ 2040 then you’ll be fine.
But he does have layers of human and it may have gone over our heads!
Definitely not a joke, it’s not the first time he speaks about it. And I promise I can tell when he’s being ironic ;)
dr mike regards himself as highly optimistic. you can see this in other podcasts as well. he really believes that progress, be it in AI or in medicine, will only exponentially improve more and more and be able to achieve results that sound absurd today.
Dr Mike isn't joking about that. I've listened to him rant about it ad nauseam and he does believe we will reach longevity escape velocity in the 2040s
No, 2040 things was absolutely not a joke. He had a really good discussion about it on Dr. Mike’s podcast, he believes science will make insane leaps in the next few years.
Maybe have a dislogue with "The Other Dr. Mike" ftom NY who deals with middle and lower class clients and the truuths of their lives...multiple jobs, no health insurance, few health education opportunites, lack of childcare. While i appreciate the mission to bring health to the masses, i don't know if concierge health care can make a dent for the population that needs it most.
People just reacting to each other’s videos. The future is now.
If you agree with dr Mike on this many things you get my subscription. Looking forward to viewing your content b
Thanks for staying on current events on youtube, of that bald guy is really trending and on so many podcasts.
That was fun :)
Though a little alarming, how so many people think that "if we just wait and do nothing aging will be solved in 20 years"
I recommend watching Dr. Mikes full video on the RP channel. He goes into that in more detail on this subject. I’m also surprised in how he is in scientific breakthroughs the next 15~20 years.
But hey, let’s hope he’s right!
@@nicholasarapis Did that already - he is one of my favorites!
I've visited Harvard Medical to speak about aging biology progress last year (for my own channel) and with the current levels of funding, interest (and misinformation) we'd be very lucky to see something this century...
**also fact checking the 2040 joke** 😂
Mike is the GOAT
Great video. I like this format a lot
To be fair, although I don’t have a PhD in anything related, I could have told you to stay lean and strong and not eat garbage. This is just common sense at this point.
That is one of the reasons you know that Mike is being honest... His advice is logically rather than fanciful 😊
Bro got peer reviewed XD. We need more of this.
We need more high quality Sci Comm and discourse in the health and fitness space.
We've had enough of bro science.
Love the high quality educational and informational content of both of you put out for free.
I look forward to joining you after finishing my degree.
The problem (I think) sometimes with dr Mike Is that a lot of thing he says is on the presumption that everybody wants to build huge muscles.
I'm going to join the consensus here. Periodic videos in this format are great and Dr Mike is one of the funniest guys on YT. But I'll add a question that I would love to see Matt address one day: what does think about the idea constantly repeated by De Grey that caloric restriction mimetics like Rapamycin are not very effective for long-lived species like ours because evolution had no reason to adopt mechanisms to combat long famines (as opposed to short ones)? He keeps repeating this idea to his broad audience in the longevity space but I've never seen it addressed head-on by Matt in any of his many Rapamycin videos. Thanks.
Love me some Dr Mike!!!
Keep keep going of hit that 10k 📈. And have on more and more prominent guests
Dr Mike is great. Learned a lot of exercise science from him.Yeah his NMN suggestion was crap, but everything else is pretty spot-on.
I follow Dr Mike, love his content. Great critique.
Love mike, i learned everything about the gym from him. Great video.
afaic Dr.Mikes opinion on the future is based on A.I solving almost all problems in all fields, with it soon becoming far more capable than humans. Having A.I going from non existant 5 years ago, to a major tool in almost all sectors, while still improving rapidly is probably his basis on all the exponential growth.
4 minutes in he has already critiqued 2 things so far he did not claim xD
Dr Mike rocks
Lol fun video and nice change of pace. I say do this kind of content every once in a while, but not too much 😊
We agree about every once in awhile. Thank you for your support.
- Nick
Great format for a different take on what's "out there"...
Great video, guys. I'm happy I stumbled upon this.
Any idea why he singled out FRESH fruits and veggies as being ideal? Wouldn't frozen be just as good?
Frozen or heavily refrigerated is often better! It preserves the quantity of some temperature sensitive nutrients like vitamin C.
In a sense, frozen is fresh IF frozen within a short time of being picked. All comes down to definitions, I think.
I like the format!
Dr Kaeberlein, are you still of the opinion that it is non-essential that the first meal of the day is in the morning for best longevity?
Great video as usual. Would love to see your take on Greg Fahy’s work
Found your channel because of this - cheers
Cheers!
wouldn't smaller body require less food for maintenance and thus lower consumption and production of AGEs for example?
I think Mike's comment re science will solve aging by 2040 was mostly a joke.
If you watch a lot of Mike's talks half of what he says is either sarcasm or a joke. He just can't help himself
People have been claiming for centuries that a cure for aging was "just around the corner." Not an intelligent comment by a so called intelligent expert...
I don’t think so, Dr Mike has thrown 2040 out several times in his videos and seems to very genuinely believe that we will continually see exponential growth in computing power and unimaginably powerful ai will soon exist that solves every problem humanity has or could have
Hi Matt and team, could you give us some thoughts on GlyNAC ? A couple of studies from Houston seem compelling with regard to old age function, if not on longevity per se.
Great suggestion! We’re on it.
- Nick
I watched because you had Dr Mike on the show.
You should update the title to include the fact that Dr. Mike has a PhD. Ie Dr. Mike Israetel.
What are your thoughts on rosmarinic acid? According to the study- Plant and fungal products that extend lifespan in Caenorhabditis elegans, it increased the life span of nematodes by 63 percent.
5' 6", wow, they spotted Dr. Mike 8 whole inches!
If Dr. Mike does believe in humanity conquering longevity by 2040, it's probably just a defense mechanism to justify his steroid use.
He's willing to accept the fact that steroid use might shorten his life, but believing in a fast approaching cure-all gives him at least some hope that he might not have to pay the piper. It's a mild form of denial of his fear of dying young.
Soooo Ive just heard about this thing called TMG and then remembered that you guys had a negative response to NMN or something like that which was suggested to be used alongside TMG . . . .can you guys give me the correct story, is TMG good for you or is it bad like what I think you say NMN is and why? thank you - feel free to just point me to a video if you already discussed TMG somewhere.
You know, Dr. Mike was joking about the 2040 immortality right?
It's either they completely missed the joke or, they ignored it just so they can have something to criticize 😅
He’s not really though. He was talking a lot about these concepts in his interview with the other Doctor Mike.
@@glassman3333exactly.
I also understand where he's coming from. I'm not an IT expert, but read a book about AI. If we look at the game of chess, we've been playing this game for hundreds of years. We gathered knowledge about it, wrote books about it and some mastered the game by thousands of hours of practice.
Then we build chess computers with rule based software. "if opponent does this, then computer does this".
Those computers were pretty good, to the point they could beat chess masters.
Then with AI we build a new sort of chess computer, not rule based anymore. It looked at thousands of games between chess masters and learned the patterns in their strategies. This AI chess computer was so good it beat the rule based computer 100 to 0 and also beat chess masters 100 to 0.
You now have an AI computer that is way better than what we as humans gathered in hundreds of years.
Now the scary part is, someone made a 2nd AI chess computer. This time the computer didn't learn patterns from watching humans play. It only knew the rule book of chess and played thousands and thousands and thousands of games against itself, learning new patterns, finding out what works and what doesn't, to the point that it now created its own never before seen strategies. This AI chess computer version 2 now learned chess with basically no human intervention, besides a human inputting the rule book of chess in the beginning.
This version 2 computer played against the version 1 AI computer (the one who learned patterns from seeing masters play) and beat that computer 100-0 in 100 games.
So just as an example of how AI learned itself to play chess in a few hours (by simulating those 1000s of games), and got to a level sooo much higher than anything we as humans could reach after hundreds of years of playing this game.
We are used to a certain pace in developping in science, but one new AI application can disrupt everything we thought we knew about how long it takes to develop in certain areas.
One very interesting topic in that regard is DNA research. It's extremely complicated to find out which part of the DNA is which gene. It used to take multiple PHD students multiple years of their time to find 1 part gene. At the pace we were going before AI it would have probably taken us multiple centuries to find out all we want to know. Not to mention the cost to fund those PhD researchers. AI now started doing this research for us and every part it learns to solve, makes it better, faster, more efficient, to the point that it might figure out the entire function of all genes in a matter of a few years.
This is huge in researching causes of disease, and thus in solving the diseases.
However at the same time I'm not sure if we will be able to keep up with all this new knowledge and if we can really market new medicines very fast, given FDA protocols and so on.
No, he genuinely believes that. He's talked about it on tonnes of podcasts
yep Mike is a funny channel.
the 2040 thing was tongue in cheek by mike right?
Debate! Please!
The candle that burns twice as bright burns half as long. High performance training is not improving longevity (as some VO2 max pushers claim).
This was fun!
PS. It seems that partial reprogramming is moving much faster (research and development-wise) than many other geroscience-related sub-fields. Is that a fair assessment?
Subscribed
Lol, we've come full circle. Reactions to reaction videos. 😂
Hoping RP reacts and keeps it going 😂
2:20 both.
With regards to celluar re-programming: What would happen if it could be achieved through natural compounds ? Then it wouldn't need FDA approval ,or could you just go to that secret island that isn't secret and have it done there in 2030 ? Since its to governed by the FDA.
Saying that 240 lbs is not optimal, I understand the rational. However, at what height? Doesn't height come into plain? To shorter people live longer? How about a 6'1 person at 240 vs. a 6'5" person at 240. If I was 6'5" or taller, I would not want to be under 200 lbs. Why no mention of how height factors into the equation.
I'd love to know what is optimal for my height at 6'3".
on average shorter people do live longer
What about NMN? Can you explain more? You just said "he doesn't know the science" - but please elaborate on that :)
We have talked about NMN in more depth in the following video:
ruclips.net/video/OgsfIUfuyqk/видео.html
@@nicholasarapis thank you!
You know what really helps longevity and health? NOT taking huge amount of steroids for the single purpose of prancing in a g strings for the enjoyment of some people.
Addicts arent people to take your health cues from.
For me it's always been high carbs and enough protein and small amounts of fat.
What's the deal with MNM? I feel like I've read a lot it longevity and MNM. I think I've heard people say it significantly increases life span but that seems a bit optimistic.
Love he says minimally processed foods but then says seed oils are healthy. They are super processed.
Mike has muscle and the other guy doesn’t so Mike is correct ✅ 😂
So, doesn’t he in part mean maintaining a lighter bodyweight drastically reduces all sorts of negative health outcomes that reduce longevity?
Could you expand on what you mean by growth signals during development and smaller body size? Does smaller body size just refer to shorter individuals or is it a weight based thing referring to people with skinnier frames?
Body size and aging is explained in more detail in this video.
-Nick
ruclips.net/video/Fjh6WbkZkvw/видео.htmlsi=aewpsi63owd8qIm5
@@optispan Thank you! Interesting video.
Dr mike is a g, great video
Bodybuilding mentality is not a perspective that helps most people. It is by design an extreme approach and its focus is not based on health. Bodybuilding has an aesthetic goal and almost every thing else is sacrificed. BTW the steroids he takes pretty much eliminates him as a good mentor.
You were supposed to start beef! Where’s the DrAmA!! Blood for the blood god! Jk yeah, he’s legit. This was great. I like this idea of “peer reviewing RUclips videos”.
Minimally processed yet SEED OILS
I feel like they are underestimating AI.