Exercise and Brain Health 101 w/ Christiane Wrann

Christiane D. Wrann, DVM, PhD
Leader of the Program in Neuroprotection, Exercise Cardiovascular Research Center and McCance Center for Brain Health at Massachusetts General Hospital;
Assistant Professor of Medicine, Harvard Medical School;
Associated Faculty, Harvard Stem Cell Institute
Dr. Wrann provides an overview of our current understanding of how exercise improves brain health, emphasizing its neuroprotective effects for Alzheimer’s disease. Her talk covers clinical studies in humans and mechanistic studies in mice - discussing functional data, cellular correlates, and molecular mediators of exercise benefits in the brain. Lastly, Dr. Wrann presents exciting new research from her laboratory on the exercise hormone irisin as a crucial regulator of cognitive benefits in exercise and a possible drug target for Alzheimer’s disease.