Celecoxib (Celebrex) and other COX-2 Selective Inhibitors

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  • Опубликовано: 4 окт 2024

Комментарии • 75

  • @haleygrefenson3288
    @haleygrefenson3288 3 года назад +7

    Please make more pharm videos! These are great!!

  • @wooly1950
    @wooly1950 3 года назад +3

    Celebrex 400mg was extensively prescribed in Australia when it hit the market, then was taken off because of the risk of heart problems, now only Celebrex 200mg is still available. I have endured eleven back operations, plus shoulder reconstruction and other surgeries brought on from an auto accident, also have arthritis in quite a few areas. I take the 200 mg around 4 to 5 days a week to help with the inflammation as it is the only anti inflammatory product that doesn't give me chronic heart burn, and no other side effects. Thank you for your great content.

    • @ChristopherGray00
      @ChristopherGray00 Год назад

      maybe the solution is to have an NSAID that is biased for cox-2 inhibition but still has a significant amount of cox-1 inhibited at the same time to possibly counteract the blood clotting effect seen when only cox-2 is inhibited.

  • @reallifepsych3309
    @reallifepsych3309 3 года назад +9

    love it here!

  • @syedshaheer8162
    @syedshaheer8162 3 года назад +2

    Please make Videos on Corticosteroids, Antihypertensive and Anti-diabetic drugs. Love the details you put in your videos.

  • @jkd6969
    @jkd6969 6 месяцев назад +1

    Five years of celebrax use helped me with arthritic pain but has caused bleeding gums and severe mouth allergies.

    • @Lian-ez8gx
      @Lian-ez8gx 4 месяца назад +1

      Have u also experienced eye pain and feeling of tooth crawling?..

  • @lunarhealer6667
    @lunarhealer6667 2 года назад

    Yay, you've gotten me through basically half of my classes haha. Now I'm in pharmacology!

  • @hunteralexander6251
    @hunteralexander6251 3 года назад

    Would love to see more of these videos! You're a great teacher!

  • @jakemilburn
    @jakemilburn 3 года назад +1

    Can you talk about Prions, specifically ones that are dangerously spreading among deer as Chronic Wasting Disease, and that scientists are worried might spread to humans in the future?

  • @Delighted-RejoicingInYah
    @Delighted-RejoicingInYah 3 года назад +1

    Thanks!

  • @YouMockMe
    @YouMockMe 3 года назад +1

    Good to know!

  • @rubyneedville
    @rubyneedville 15 дней назад

    I got hard heart burn ended up in ER. Never gave I felt this in my life. I would rather have back pain

  • @12345.......
    @12345....... 3 года назад +4

    Would you consider a series on antidepressants?

    • @wolvenar
      @wolvenar 3 года назад +1

      I second this.
      Would be a rather long series I would guess, so many approaches these days.

    • @WhyDoYouExistX
      @WhyDoYouExistX 3 года назад +1

      Yeah. I'd like a complete breakdown on mirtazapine/remeron, and explain why it makes people sleepy, and why the lower doses do it but the higher ones not soo much. And answer the question question I have that is, does it however, inhibit REM sleep?

    • @wolvenar
      @wolvenar 3 года назад

      @@WhyDoYouExistX FYI you wrote the word "question" twice :-) I love how that goes unnoticed so easy.

    • @cps_Zen_Run
      @cps_Zen_Run 3 года назад +1

      Better perhaps is to evaluate one’s nutrition and lifestyle.

    • @12345.......
      @12345....... 3 года назад +1

      @@cps_Zen_Run fair point

  • @marshallahonen
    @marshallahonen 3 года назад +2

    Question for you: Do you have any experience with instruction of STEM to individuals with dyscalculia?

  • @backstreetfan2887
    @backstreetfan2887 3 года назад +1

    good information, thank you

  • @ParthGoyal
    @ParthGoyal 3 года назад

    Lovely

  • @cps_Zen_Run
    @cps_Zen_Run 3 года назад +6

    Drug prescriptions treat the symptoms and rarely, if ever, the cause. Remember, healthcare is primarily Sick-care. Start with nutrition. Avoid refined sugars, processed foods, and vegetable/seed oils. May you stay healthy and safe.

    • @realtalk37851
      @realtalk37851 Год назад +1

      that shitt doesnt work.Youll still have pain regardless

    • @sbocaj22
      @sbocaj22 2 месяца назад

      @@realtalk37851100% can make a difference. I thought it didn’t but I was wrong. It does

  • @dhirajkarthik1234
    @dhirajkarthik1234 3 года назад

    I love it this mechanism of action

  • @siddharthamaji6027
    @siddharthamaji6027 3 года назад

    Professor you are great.

  • @doctorofpharmacy204
    @doctorofpharmacy204 3 года назад

    This is superb

  • @ughsirius
    @ughsirius Год назад +1

    thank youu

  • @lorddonk9806
    @lorddonk9806 3 года назад +1

    Can you do a video about the nuclear structure? As in the shells and magic numbers so to speak. I believe the nucleus is structured in a way similar to how the electron orbitals are structured, in that they are probability areas. But that is really all i know. Im a normal chemistry major now, but have plans to go to grad school for nuclear chemistry. I like the physics side of chemistry a lot. Nuclear, quantum, theoretical chemistry are my main areas of interest.

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  3 года назад +3

      check my tutorial on nuclear reactions

    • @lorddonk9806
      @lorddonk9806 3 года назад +1

      @@ProfessorDaveExplains roger that sauce boy

    • @lorddonk9806
      @lorddonk9806 3 года назад

      @@ProfessorDaveExplains ive checked your video. I like it. Nice explanation. I do have another question.
      Now there is a strong nuclear force that holds protons and neutrons together in the nucleus? What is doing the holding. How can we hold these particles together? What is the particle behind the strong force?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  3 года назад

      they're called gluons, check my tutorial on quantum chromodynamics it explains it a little bit, but i hope to do extensive content on particle physics later

    • @lorddonk9806
      @lorddonk9806 3 года назад

      @@ProfessorDaveExplains so we have gluons that connect protons together. But electromagnetic repulsion still exists and gradually overpowers the nucleus as it gets larger.
      So how does the nucleus orient itself to minimize the electromagnetic repulsion.

  • @Felixkeeg
    @Felixkeeg 3 года назад

    Kinase inhibitors next? Or Inhibition of epigenetic moderators (Methyltransferase, HDACs, an so on)?

  • @annap1191
    @annap1191 Год назад

    Great video. Can you take efexor and celebrex together?

  • @palantir135
    @palantir135 3 года назад +1

    Yes, I had all of the side effects of the cox2 inhibitor. I survived.

    • @Lianne-qm4yp
      @Lianne-qm4yp Месяц назад

      May I ask what were the side effects?..

    • @palantir135
      @palantir135 Месяц назад

      @@Lianne-qm4yp acid reflux, stomach cramps, bleeding in my intestines, out of breath, sleeplessness, diarrhea etc.

    • @Lianne-qm4yp
      @Lianne-qm4yp Месяц назад

      Have you experienced brain fog? And change of state of mind?..

    • @palantir135
      @palantir135 Месяц назад

      @@Lianne-qm4yp no, not in the slightest

  • @JohnSmith-qt4pv
    @JohnSmith-qt4pv 2 года назад

    What if you took low dose aspirin alongside Celebrex to reduce the risk of clotting?

  • @hamdamohamed5683
    @hamdamohamed5683 3 года назад

    This is best video thnx

  • @cuteworld4984
    @cuteworld4984 3 года назад

    I need more please 🙏🙏

  • @davidsweeney111
    @davidsweeney111 3 года назад

    Could you do a video on glyphosate (roundup), does the chemical structure look like a human neurotransmitter? GABA?

  • @brittanyjacobson5199
    @brittanyjacobson5199 3 года назад

    very interesting

  • @kylebonini6117
    @kylebonini6117 3 года назад +1

    I'd like him to be my science professor in college

  • @chrstphrdyer
    @chrstphrdyer 2 года назад

    What do you think about H2max?

  • @phsura5833
    @phsura5833 Год назад

    References??

  • @Gwallacec2
    @Gwallacec2 3 года назад

    Can you do Lodine?

  • @bruhman2478
    @bruhman2478 3 года назад

    What’s your response to sky scholar’s debunk on you?

    • @ProfessorDaveExplains
      @ProfessorDaveExplains  3 года назад +2

      Um, to laugh hysterically at the fact that he debunked precisely nothing.

    • @bruhman2478
      @bruhman2478 3 года назад

      LOL that’s true

  • @alexandruionut8553
    @alexandruionut8553 3 года назад

    love so much the series

  • @ladlakhan759
    @ladlakhan759 3 года назад +1

    Hello Sir, if you also start driving licence, may be it will be very better for us and you

  • @Marytere8
    @Marytere8 3 года назад

    👏👏👏👏

  • @CM-ng1ef
    @CM-ng1ef 3 года назад

    bueno

  • @syrupgoose8131
    @syrupgoose8131 3 года назад +1

    Can I get an F in the chat for nothing at all

  • @FreemanVashier
    @FreemanVashier 3 года назад

    Morn'n

  • @ladlakhan759
    @ladlakhan759 3 года назад

    Because many people want to get the driving licence,

  • @Donald_Trump_2024
    @Donald_Trump_2024 3 года назад +2

    QUICK START PRAYING TO GOD BEFORE THE ATHEISTS ARRIVE AGAIN!

    • @12345.......
      @12345....... 3 года назад +5

      Fuck off. We're already here.

    • @OldBenOne
      @OldBenOne 3 года назад +3

      @@12345....... You lose - You forgot to use all caps.

    • @wolvenar
      @wolvenar 3 года назад

      @@12345.......
      Wow, nice language you use in what's effectively a classroom.
      Also, thanks for showing how tolerant you are of differences of people.

    • @12345.......
      @12345....... 3 года назад +1

      @@wolvenar exactly. Like the initial comment on this thread. If you are offended by bad language, you should not be in the comment section.

    • @Jabbatic
      @Jabbatic 3 года назад +3

      Which god, why, where and how? Did you have a specific magical, invisible, immaterial, imaginary, immortal, supernatural, anthropomorphic sky-genie in mind?
      Have you tried the classic Greek god Koalemos? That particular sky-genie always strikes me as apposite when is comes to religious belief of all flavours and varieties.