Sodium Potassium Pump ( Na⁺ / K⁺ - ATPase )
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- Опубликовано: 22 июл 2024
- #SodiumPotassimPump #SodiumPump #PotassiumPump
Sodium Potassium Pump ( Na⁺ / K⁺ - ATPase )
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▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬
The sodium-potassium pump (sodium-potassium adenosine triphosphatase, also known as Na+/K+-ATPase, Na+/K+ pump, or sodium-potassium ATPase) is an enzyme (an electrogenic transmembrane ATPase) found in the membrane of all animal cells. It performs several functions in cell physiology.
The Na+/K+-ATPase enzyme is active (i.e. it uses energy from ATP). For every ATP molecule that the pump uses, three sodium ions are exported and two potassium ions are imported.[1] Thus, there is a net export of a single positive charge per pump cycle. The net effect is an extracellular concentration of sodium ions which is 5 times the intracellular concentration, and an intracellular concentration of potassium ions which is 30 times the extracellular concentration.
The sodium-potassium pump was discovered in 1957 by the Danish scientist Jens Christian Skou, who was awarded a Nobel Prize for his work in 1997. Its discovery marked an important step forward in the understanding of how ions get into and out of cells, and it has particular significance for excitable cells such as nerve cells, which depend on this pump to respond to stimuli and transmit impulses.
All mammals have four different sodium pump sub-types, or isoforms. Each has unique properties and tissue expression patterns. This enzyme belongs to the family of P-type ATPases.
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Dr. Najeeb where can i found parts 2 and 3 . i cant find them on webpage.
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can we have the next part of the video to understand regulation pf pump
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im a member of your class yet am traying to find the 2nd part of your lecture which explain the regulatiion and role of the pump..
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Sir I took subscription of your videos in that too I didn't find the part 2 of this video
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