Is Aging Reversible? A Scientific Look with David Sinclair | David Sinclair | TEDxBoston

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  • Опубликовано: 7 июн 2024
  • NOTE FROM TED: Research around aging discussed in this talk remains an ongoing field of study. Please do not look to this talk for health advice. TEDx events are independently organized by volunteers. The guidelines we give TEDx organizers are described in more detail here: storage.ted.com/tedx/manuals/t...
    Have you ever wondered how long you will live? And if so, how could you change that number to live drastically longer? The science might be in your favor: follow David Sinclair, Australian biologist and professor of genetics at Harvard University, as he shares his research on slowing and reversing the process of aging in mice, and how the same technology may someday be transferable to humans. David Sinclair, Australian biologist and professor of genetics at Harvard University, shares his insightful research into the science of age reversal and anti-aging medicine.
    David Sinclair, Australian biologist and professor of genetics at Harvard University, shares his insightful research into the science of age reversal and anti-aging medicine. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx

Комментарии • 1,3 тыс.

  • @cosmotagliafierro8055
    @cosmotagliafierro8055 2 года назад +1397

    My right eye has a crushed optic nerve (caused by high IOP (intra occular pressure)) - which has resulted in about 5% vision in my right eye ( practically useless).
    At the 12 minute mark David talks about treatment that reprogrammed a mouse's optic nerve to regenerate.
    I would gladly volunteer for such a study - I mean, what do I have to lose - the vision in my right eye is already gone.
    I wish my comment ( much like, a "message in a bottle"), would find its way to Professor Sinclair.

    • @johnblasiak9331
      @johnblasiak9331 2 года назад

      Tryantiwontigongolo

    • @AAA-of4vk
      @AAA-of4vk 2 года назад +2

      he cannot do that

    • @rylaczero3740
      @rylaczero3740 2 года назад +5

      This will be mutually beneficial

    • @blacked2987
      @blacked2987 2 года назад +30

      *we need people like you brah!* 💪🏼

    • @Aldraz
      @Aldraz 2 года назад +20

      I think he was talking one day about gathering some volunteers, but that might have been for something else. Either way, I think you may wait for a year or 2, but the technology is going to be there pretty soon I believe. If it works in mice and human cells and whole organs, there's only legislative and ethical reasoning slowing this down. They can also use mRNA tech to deploy it anywhere in the body, so I think it's really gonna be pretty soon and change the world.

  • @glowsea5185
    @glowsea5185 Год назад +19

    I ve been folowing davind sinclair since a was 37 years old .
    Now I m 31 !

  • @anon69669
    @anon69669 Год назад +362

    David is really ahead of the curve. He deserves more funding and attention

    • @jasperstoj
      @jasperstoj Год назад +6

      He is in charge of a lab at Harvard and said on JRE that he runs multiple companies. I think he's good to go!

    • @iche9373
      @iche9373 Год назад

      And thanks to Sinclair, you can't buy NMN free from the market anymore, only through his biotech cartel.

    • @fullmoon1072
      @fullmoon1072 Год назад +7

      @@jasperstoj but he needs to get all this stuff available to everyone and push this new learning to doctors worldwide!

    • @andrewnorris5415
      @andrewnorris5415 Год назад +4

      I believe he is mega rich already, resveratrol.

    • @iche9373
      @iche9373 Год назад +5

      David Sinclair is just a millionaire

  • @emyoji1316
    @emyoji1316 7 месяцев назад +31

    I thought this guy is in his 30's. His research is really working for him.

    • @lmfao69420
      @lmfao69420 5 месяцев назад

      Exactly haha

    • @black_squall
      @black_squall 2 месяца назад

      I watched a video where you can see his face closer up and it looks like he's got plastic surgery...

  • @jamesroof6150
    @jamesroof6150 Год назад +38

    A human worth listening to. No one gets my time unless it is constructive, positive and expands knowledge and wisdom.

    • @weeklydaily4775
      @weeklydaily4775 Год назад +3

      Giving up time for this guy makes sense - cause he's offering you more time alive

    • @billyjolly4855
      @billyjolly4855 Год назад +4

      Same for me, haven't heard anyone interesting for a long time. This guy gives me hope

    • @TNT-km2eg
      @TNT-km2eg Год назад

      Don't forget to subscribe

    • @glitterbug8808
      @glitterbug8808 Месяц назад

      Love this

  • @jimmykelly2809
    @jimmykelly2809 2 года назад +111

    He looks younger every time I see him. Incredible

    • @Myrslokstok
      @Myrslokstok 2 года назад +2

      Maybe the cookie 🍪 jar 🏺 is actually empty.

    • @sterlingrooke4712
      @sterlingrooke4712 2 года назад +20

      Great facial esthetic treatments (Botox etc). Notice almost zero facial express on his forehead.

    • @jeffreylatham3307
      @jeffreylatham3307 2 года назад +8

      @@sterlingrooke4712 maybe, but then again maybe not. he has been self treating himself with his discoveries for over a decade. If any of what he says is true, which we know at the majority is in some way, then why wouldnt he look younger if all his cells are genetically younger than they were before?

    • @5minsleft542
      @5minsleft542 2 года назад +1

      @@jeffreylatham3307 maybe younger at this point for him is reversing the health and age of internal organs rather than the look on skin. But again, elastic skin is also a sign of youthful body. This is only the beginning of tackling aging, I'm glad that the mainstream now are aware of this novel, 10 years ago most people would not have a single thought regarding this subject

    • @lifespanextensionresearch8518
      @lifespanextensionresearch8518 Год назад

      Hi how is your age reversal going?

  • @rodrigodaux7439
    @rodrigodaux7439 2 года назад +369

    David is a legend. Hope he lives forever and so do we. Thanks for sharing tour knowledge

    • @TGTRODON
      @TGTRODON 2 года назад +7

      @Call For An Uprising amén brother

    • @adrianjohn.
      @adrianjohn. 2 года назад +2

      @Call For An Uprising
      Amen Teacher:)

    • @PP-vf1kx
      @PP-vf1kx 2 года назад +5

      …if nobody dies…tyrants n criminals would be everyone worst nightmare 🤔

    • @adrianjohn.
      @adrianjohn. 2 года назад +1

      @WolfOfPackMan
      oh yeah yeah

    • @sleepsmartsmashstress740
      @sleepsmartsmashstress740 2 года назад +4

      forever - REALLY?

  • @MisakoYoke
    @MisakoYoke Год назад +13

    David looks younger than in his TEDx talk in Sydney 10 years ago. I think it's working.

  • @IemonandIime
    @IemonandIime Год назад +673

    This guy is 53 but looks 35. I think he knows what he's talking about

    • @landoakechi9406
      @landoakechi9406 Год назад +58

      Honestly, if he said he were 25, I'd believe him

    • @tony9622
      @tony9622 Год назад +67

      @@landoakechi9406 25? Man looks 40

    • @JuanJacinto
      @JuanJacinto Год назад +32

      @@tony9622 He's closer to 60 than he is to 40

    • @Wolfy39565
      @Wolfy39565 Год назад +6

      hes not 53. thats bull

    • @mercerwing1458
      @mercerwing1458 Год назад +27

      @@Wolfy39565 He is

  • @techwithdipufrom0ton621
    @techwithdipufrom0ton621 Год назад +26

    The saying" Death is inevitable" should inspire us to live a health life instead of panicking. When Sinclair says" Death is a disease" it really challenges my traditional view on death. I believe now that Death is a disease and since every disease is treatable, there's no reason why death can't be cured, or at least slowed down or increasing the lifespan by as much as 100 years , which is like having another life experience.

    • @thezeronelite
      @thezeronelite Год назад +5

      Like any machine, proper maintenance can vastly advance the lifespan of the human body.

  • @tonythetraveller9759
    @tonythetraveller9759 2 года назад +193

    So informative, but also nice to see somebody doing something they are really passionate about. This is clearly David's life mission.

    • @lifespanextensionresearch8518
      @lifespanextensionresearch8518 Год назад

      Taking any geroprotector supplements?

    • @george4658
      @george4658 Год назад +1

      The next sir Dr Fred hollows

    • @McNabb99
      @McNabb99 Год назад

      It’s admirable, but he sold his discovery for over $70 million. The lab then ditched resveratrol because the human guy can’t absorb it.

  • @darthkrayt4369
    @darthkrayt4369 8 месяцев назад +8

    This science has so many positive implications.
    I recently did something awful and hurt many people close to me, I am experiencing tremendous shame for my actions and was suicidal for a time.
    I am so glad I didn't now, as this means we can recover from anything as personal growth is essentially unlimited.
    I know that I'll never be so shallow as to betray someone I love again, and now I may have eternity to prove it!

  • @paulginsberg6942
    @paulginsberg6942 Год назад +20

    One of the very best researchers and a great person.

  • @DoctorJack16
    @DoctorJack16 Год назад +6

    Love it! What an exciting time to be alive!

  • @omittapir5986
    @omittapir5986 Год назад +20

    So good to see him again after quite a break. Dr Sinclair please do some more podcasts. Missing your guidance and knowledge immensely!

  • @emmanuelweinman9673
    @emmanuelweinman9673 2 года назад +162

    The real battle is against fear and hate. Years of stress will drastically shorten one’s life.

    • @ObsessiveVolunteer
      @ObsessiveVolunteer 2 года назад +10

      Yoga

    • @johnblasiak9331
      @johnblasiak9331 2 года назад +2

      Yoghurt

    • @reubenrichardson3336
      @reubenrichardson3336 2 года назад +12

      Well the idea is that if you use the natural aging defenses (mTOR, AMPK and Sirtuins), you can still enjoy as much fear and hate as you would like to AND live longer. Its a win-win.

    • @emmanuelweinman9673
      @emmanuelweinman9673 2 года назад +2

      @@reubenrichardson3336 fear and hate still sound like a loss to me 😂

    • @lanceanthony198
      @lanceanthony198 2 года назад +2

      Fear and hate? Not really lol

  • @Exen88
    @Exen88 Год назад +22

    David Sinclair steps out of the bound and think out of if it. We need more scientist like this. I look forward to following his work.

  • @noellegilbertdressgirlmeet3414
    @noellegilbertdressgirlmeet3414 2 года назад +251

    Brilliant. This man is absolutely brilliant. I have watched every one of his videos and am now opening a wellness center that uses many of his principles. You can’t get around science. You can’t deny the research. Thank you Dr. Sinclair! I plan to live to 120 because of your brilliant research. My goal is to share this information with the world. I hope one day to get to meet you. That is on my vision board!!! 😃

    • @ruthenianthruth
      @ruthenianthruth 2 года назад +1

      If David is correct, then by the time of you being 120 science will proceed so far forward that you could reverse your age completely. Meaning you will be immortal.

    • @noellegilbertdressgirlmeet3414
      @noellegilbertdressgirlmeet3414 2 года назад +4

      @@ruthenianthruth I love that John! And guess what the name of my wellness spa is… Immortal Wellness Spa! Lol. I am willing to be immortal as long as my health is good. 😀

    • @ruthenianthruth
      @ruthenianthruth 2 года назад

      @@noellegilbertdressgirlmeet3414 Sounds like a plan :)

    • @L_RV
      @L_RV 2 года назад +9

      I think that dr Sinclair is not emphasising on the life span but his reasearches are more about a life with less body illnesses, which are 2 different things

    • @noellegilbertdressgirlmeet3414
      @noellegilbertdressgirlmeet3414 2 года назад

      @@L_RV Definitely a combination of both concepts. His research is based around ways to rid the body of disease and produce longevity with the use of fasting, decreasing meat consumption/amino acids, use of vitamins and pharmaceuticals, etc. to trick the body into thinking its under “stress” in an attempt to promote 3 major chemicals and pathways in the body… and of course there’s the epi-genome and the things humans do to turn off and on our innate protective mechanisms…. and how cells are turned off or on when they shouldn’t be…but that’s for another time!
      All I’m saying is his research on minimizing diseases and producing longevity is brilliant and I wish more people would embrace his advice.
      Much love and wishing us all amazing health ❤️

  • @manuelojeda9144
    @manuelojeda9144 2 года назад +43

    My grandma on my Dad's side lived to be 97 years old in Cuba. She had great vision, perfect blood pressure, strong bones. Healthy teeth. Hooray!!

    • @mrwhitemantv
      @mrwhitemantv Год назад +6

      My grandma lived to 101

    • @Panther6CofU
      @Panther6CofU Год назад +3

      Wow, that's great! I wish I had great vision and healthy teeth. I will someday soon!

    • @MyFirstHandle
      @MyFirstHandle Год назад +1

      I wish her to live an eternal life. It would be awesome to see your grandma young again, and productive.

    • @franciscoaceituno4217
      @franciscoaceituno4217 Год назад +1

      how did she died before the obvious old age?

    • @FerryPatrix93
      @FerryPatrix93 Год назад +2

      Same with my grandma and she is going to be 102 yrs old this year !

  • @katiethenaturelover
    @katiethenaturelover 11 месяцев назад +4

    Thank you for the presentations. They are very helpful.

  • @white_k_finance
    @white_k_finance Год назад +8

    David is really a legend. Thank you sir for this information.

  • @RosettaRedfeather
    @RosettaRedfeather 2 года назад +2

    Amazing. I’ve been expecting this!!

  • @pawlieblog7967
    @pawlieblog7967 Год назад +2

    Excellent news and encouraging studies!

  • @pat4043
    @pat4043 Год назад +7

    This man gives me hope

  • @MrLuba6a
    @MrLuba6a Год назад +8

    maybe the most valuable video I have seen in my entire life!!! Thanks,dr. Sinclair and may God bless you ❤

    • @TNT-km2eg
      @TNT-km2eg Год назад

      Whatever you say . Don't forget to subscrjbe

    • @kamrulz659
      @kamrulz659 3 месяца назад

      Yes, new findings so good to follow.

  • @Pleroma17
    @Pleroma17 Год назад +5

    Thank you very much sir, amazing knowledge.

  • @kevinloo9688
    @kevinloo9688 Год назад +93

    I read his book and put my parents on NMN. My dad got energy that he didn’t know he had. My mom hasn’t noticed a difference. Looking forward to 40 more years with my parents🥰

    • @FaithfulReasoning
      @FaithfulReasoning Год назад

      What is nmn?

    • @owensheasbyfitness
      @owensheasbyfitness Год назад +16

      @@FaithfulReasoning Nicotinamide mononucleotide (NMN) is one of the main precursors of nicotinamide adenine dinucleotide (NAD+) - an essential enzyme for various critical cell functions, including metabolism, DNA repair, cell growth and survival
      as you get older your body produces less i think

    • @robert7645
      @robert7645 Год назад +16

      @@owensheasbyfitness ok looked it up, found in cucumber, broccoli, and cabbage
      thanks

    • @paramedivmso4
      @paramedivmso4 Год назад

      @@robert7645 Same :)

    • @elenac102
      @elenac102 Год назад

      That's not enough, get into the longevity field and keep track of all research. You can try AkG for instance, resveratrol, quercetin, fisetin and TMG. And wait on the research which I expect to use CRISPR to inactivate the genes responsible with aging, have a look for instance at what BioViva is doing now with a modified virus CMV. Also, they will probably manage the use the yamanaka factors to reprogram most cells to the moment right after specialization. How old are ur parents? Get in touch if you would like to talk about this stuff, we can share knowledge:)

  • @royzlatanestevez9843
    @royzlatanestevez9843 2 года назад +3

    This looks so good. I'm so happy for coming generations (or first person already born, maybe in January).

  • @compucentrum
    @compucentrum Год назад +4

    I have to smile during that lecture. I have been using antioxidants exclusively for 19 years. I refuse any signaling pathway activators, flavonoids and polyphenols. The goal is that I'm as young as David Sinclair and I look so young too.

  • @robertmonds4762
    @robertmonds4762 Год назад

    Thank you David. Fabulous presentation. Pirkko from Queensland Australia

  • @crayon7369
    @crayon7369 2 года назад +36

    Mr. David Sinclair has seperate fanbase..he is amazing

  • @phoenixflower1225
    @phoenixflower1225 Год назад +8

    These are the kinds of breakthroughs that are so amazing to learn about. I wish I did science - the road is long and hard and arduous and you question your existence but the payout is so so rewarding

  • @epg-6
    @epg-6 11 месяцев назад +20

    I keep waiting for a catch even though I've been following Sinclair's work for years. It seems way too good to be true, but the results so far speak for themselves.
    Hopefully the human testing goes well. If this technology pulls through, we are in for a completely new paradigm - not just in medicine, but in the human condition itself.

  • @abraxadabra4224
    @abraxadabra4224 Год назад +2

    Fantastic! This is research I get really excited about!

    • @Acemanveryspecial
      @Acemanveryspecial Год назад

      It's research born out of love of family and the love of life, which is why it's so easy to get behind and support. I hope we can become masters of our own destiny and end aging to see all the beautiful universe has to offer.

  • @GregSemiensLive
    @GregSemiensLive Год назад +2

    Im glad all my worries and thoughts about our bodies and how they work are being answered and worked on

  • @goalhorn2012
    @goalhorn2012 Год назад +13

    I hope this technology is available to the general public. I was amazed when I read what he did to mice!

    • @TJMKRK
      @TJMKRK Год назад

      Yeah, it won´t

    • @goalhorn2012
      @goalhorn2012 Год назад +1

      @@TJMKRK aww

    • @ThatBlueSkull
      @ThatBlueSkull Год назад +2

      @@goalhorn2012 It will if it isn't think of all the people that will revolt because there family members are sick or dying but they can but cured

  • @pgc6290
    @pgc6290 3 месяца назад +4

    Thank god youtube suggested me this gem of a video. But wouldve also loved to hear what the right things are that should be done to live till the future, also about when he thinks this future will come (i know he has said in interviews 10 years but still).

  • @visamap
    @visamap Год назад

    Thank you all very much

  • @egeyermusic
    @egeyermusic 2 года назад +84

    So interesting, with incredible advances as sophisticated as this in all fields - yet collectively our emotional maturity has been all but neglected hence society is increasingly splintered, divisive, lost. Living to 150 will come with great responsibility to emotionally grow up. I sincerely hope we can do that.

    • @privatprivat7279
      @privatprivat7279 2 года назад +4

      its really really really sad and pathetic what humanity does to themselfs an eachother... i gess compassion for our ignorance and onconcious behaviour is the way forward... we are all fools... just feel sorry for those that c'ant/wont/want to admit it.

    • @lifespanextensionresearch8518
      @lifespanextensionresearch8518 Год назад

      Hi how is your age reversal going?

    • @diamondromeostewart8049
      @diamondromeostewart8049 Год назад

      Hello 👋 Elizabeth. How are you doing

    • @squamish4244
      @squamish4244 Год назад

      Maybe it will force us to finally grow up. As for our emotional maturity, humans have always neglected it in almost every society.

  • @generalb4005
    @generalb4005 2 года назад +79

    Thanks to David I’ve incorporated long term fasting and reduced my insulin levels significantly. I can truly tell that I reversed the aging clock by just those two factors alone. Hormesis is real and it just makes sense. I lift weights more now, cold showers, i don’t feed into a lot of drama like i used to, procrastinate less all in an effort to make sure my stress levels are low. My new focus area revolves around testosterone synthesis to make sure my hormones are balanced appropriately. That too is improving the quality of my life.

    • @jammies6228
      @jammies6228 2 года назад +1

      What’s your fasting cycle and when do you take cold showers (morning, night, both)?

    • @generalb4005
      @generalb4005 2 года назад +9

      @@jammies6228 been fasting for so long think I’m past cycles. I typically eat 1 meal a day 90% of the time and then when I feel the urge I do 72hr water only fasts. I don’t really do longer fasts mainly because I see fasting as a way of life now. So 72hrs is that sweet spot for me.
      As far as cold showers go depends on the season. In winter I prefer evenings to make sure I feel the cold water shock. In the summer mornings seem to provide colder water.

    • @iche9373
      @iche9373 2 года назад

      What about keto, meditation, metformin etc.?

    • @generalb4005
      @generalb4005 2 года назад

      @@iche9373 yep there’s tons of processes out there but the items listed above were the ones that pushed the needle for me specifically.

    • @iche9373
      @iche9373 2 года назад

      @Alberdi Red light therapy for your testicles.

  • @strategyandpolicy1445
    @strategyandpolicy1445 Год назад +3

    What a time to be alive!!!

  • @Dilligaf777
    @Dilligaf777 2 года назад +1

    This is the most exciting thing ive seen in a long time..

  • @claudiameyer5275
    @claudiameyer5275 2 года назад

    Brilliant, I'm hooked

  • @david3188col
    @david3188col Год назад +26

    This is one of those things that is so extraordinary and almost too good to be true but the science and technology does appear to be going in a promising direction. Treating aging like an illness/medical condition than just an inevitability is a giant paradigm shift.

  • @treewalker1070
    @treewalker1070 2 года назад +43

    He's 52! I'm 70 and I follow his program and it works, I feel like I'm aging backward.

    • @prostabkundu8105
      @prostabkundu8105 2 года назад +1

      What exactly the program? please if you can elaborate

    • @treewalker1070
      @treewalker1070 2 года назад +17

      @@prostabkundu8105 Basically intermittent fasting, exercise, and the supplements NMN and Resveratrol. He has many vids that go into detail about it. But he seems to be saying there have been new discoveries recently, so there may be more to it.

    • @prostabkundu8105
      @prostabkundu8105 2 года назад +6

      @@treewalker1070 thanks for your comment.

    • @treewalker1070
      @treewalker1070 2 года назад

      @@fabebn What?? Even if it were possible to post pictures on a RUclips comment section, they wouldn't show you how I feel.

    • @MacMacPherson
      @MacMacPherson 2 года назад +1

      @@treewalker1070 yes he has very recently gone almost totally plant-based, in terms of food intake

  • @SnakeAndTurtleQigong
    @SnakeAndTurtleQigong Год назад

    Thanks so much!

  • @KynaNg123
    @KynaNg123 Год назад +2

    Thank you for sharing your knowledge :) I am bookmarking Lifespan and other books :)

  • @goldinthegreen8593
    @goldinthegreen8593 2 года назад +3

    Love this guy

  • @mouradmelki1294
    @mouradmelki1294 2 года назад +23

    This guy's talk really is giving me hope
    My mother just got treated for cancer n now it came back in a different site
    N what this guy says is rlly making me feel a bit of hope that one day she will see my grandchildren
    I wish she can stay alive until then

  • @janelawrence6627
    @janelawrence6627 2 года назад +8

    I love Dr. Sinclair's talks about reversing people's age. And because of this, I love to live more to 100. I hat aging. I will be 50 on my next birthday, but many people still think I am still 30+. Very overwhelming but all thanks to NMN by vitruvin. Along with balanced diet and regular exercise, it's definitely possible to improve the quality of living and slow the aging process. If not because of his talks and also his book, I wouldnt be this healthy, fit, and youthful.

  • @r.b.somers2052
    @r.b.somers2052 2 года назад +2

    Crazy! Wish these discoveries would have been around years ago.

  • @tasospapanastasiou9274
    @tasospapanastasiou9274 Год назад +10

    At last someone who truly understands that age is just a number and that we can really reverse the ageing process! By eating properly and staying away from harmful pollutants we can live longer and healthier lives!

    • @lifespanextensionresearch8518
      @lifespanextensionresearch8518 Год назад +1

      We need advanced science and tech also. Diets and exercise will not be enough

    • @TNT-km2eg
      @TNT-km2eg Год назад

      Take care of your teeth, so you make a nice skeleton

  • @vanessawiltshire6813
    @vanessawiltshire6813 Год назад +5

    Wow. I’d be happy enough winding back to 30 but keeping the wisdom of where I’m at now :)

  • @incredulofreeman8358
    @incredulofreeman8358 Год назад

    i keep coming back to see what David is been up to, he seems to be shifting from nmn and nr. what a time to be alive.

  • @rand_longevity
    @rand_longevity 2 года назад

    Absolutely revolutionary

  • @murrmurr765
    @murrmurr765 Год назад +73

    This guy gave me 29 months with my mother who had brain cancer which usually gives you 12 months. I try to influence all my family but they have a hard time taking it seriously.

    • @keithchegwin1222
      @keithchegwin1222 Год назад +8

      Sorry to hear about your mother, my mother passed away too. What did you do to prolong her life? Was it the supplements and fasting? Thank you ❤️

    • @murrmurr765
      @murrmurr765 Год назад +6

      @@keithchegwin1222 Fasting, diet, supplements and immunotherapy. I'd say the immunotherapy was the least effective measure. How are you holding up? It's very hard for me.

    • @murrmurr765
      @murrmurr765 Год назад +1

      @@keithchegwin1222 Thank you too ❤️

    • @keithchegwin1222
      @keithchegwin1222 Год назад +10

      @@murrmurr765 Yes it is hard, I wear a neckless with her fingerprint on it which helps. I use the loss of my mother as strength. I think 💬"what would my mother want me to do".
      After she died I started to wake up, I got married and I also set up a business that I enjoy and pays a lot more than my last job. All this is because my mother gave me the strength to do it and take action.

    • @marileighschulte2387
      @marileighschulte2387 Год назад

      What is NAD therapy ?

  • @cyrilsteger
    @cyrilsteger Год назад +60

    Everytime I see Dr. Sinclair he looks younger than before. Proves that his theory is true.

  • @Neurowill
    @Neurowill 2 года назад +13

    Sinclair Nation! We love Sinclair! 🤜🤛🧠🧬

  • @MissKaylie96
    @MissKaylie96 2 года назад +1

    This is amazing, wow

  • @adamloepker8057
    @adamloepker8057 Год назад

    This is astounding

  • @bisousmeable
    @bisousmeable 11 месяцев назад +3

    Thank you David for this incredible information. What brand of NMN do you recommend and how much daily? Take care & keep up fighting for the planet & humanity :)
    Side note: I've been doing interminttent fasting for the past year but working out / running & weights for the past 30 years and those things def do help!!!

  • @bellehamilton3395
    @bellehamilton3395 2 года назад +8

    It's difficult to evaluate something with no visible consequences, but the research points to a positive outcome. It's probably best to utilize while you're under physical duress. This product has met my expectations in that it has made me feel more energetic in the morning and throughout the day since I started using it. I'll keep taking Vitruvin Health Anti-aging supplement since it keeps me energetic throughout the day.

    • @annewilliams9279
      @annewilliams9279 2 года назад

      So far, I've been experiencing a positive outcome ever since I am taking this product.. 😇🤩 Except that I had a trouble sleeping during the first few nights as I am still hyped up. The energy that Vitruvin supplement gives me is so overwhelming...but now this is best recommended. 😇

    • @MichelleEinsteinSongBirdsong
      @MichelleEinsteinSongBirdsong 7 месяцев назад

      I believe we're suppose to be awake for 12 hours and sleep for 12 hours (The brain heals during sleep).

  • @cooperman252
    @cooperman252 Год назад

    awesome talk.

  • @dojagi1461
    @dojagi1461 Год назад

    I want to learn as much as possible from this life experience wise and then move on. Living is about experiencing and growing spiritually.

  • @heinousanus9352
    @heinousanus9352 Год назад +10

    I love this dude. He should be more famous than Elon & have more funding too.

  • @barrysmith8193
    @barrysmith8193 11 месяцев назад +3

    Living a longer life is a thrilling idea whose time has come. The secret to the success of this will be resilience. Resilient to the stress that the media, the food cartels, and the politicians daily create for we citizens. Only the names and faces have changed. Here’s to a long and healthy life for all of us. Cheers.

  • @hyacinthkalu1218
    @hyacinthkalu1218 Год назад

    Outstanding

  • @dillisherma678
    @dillisherma678 2 года назад

    Thanks tted n David...providing this important video also with nepali subtitle.Also request n w;d b grateful if all the videos also with nepali subtitle.

  • @ronaldvasquez6748
    @ronaldvasquez6748 Год назад +87

    Interesting. I wish I could be 21 years old again and stay 21 forever. I know that’s not how it works but it’s my dream 😊

    • @Guidus125
      @Guidus125 Год назад +28

      Well, given that this research has already progressed to the point where it can reverse aging in rodents, I don't think it's unthinkable that you might be able to fulfill that dream one day. I guess it depends on your current age and whether you'll be alive by the time that this research is successfully translated to humans.

    • @jeffamg
      @jeffamg Год назад +21

      @@Guidus125 It really feels good to read, I'm 38, we all make mistakes in life, I feel I really started living last year, understanding myself and living my best life. I'm in amazing shape , running a lot, going to gym, eating good. I always been anxious, I wish I would have been more grateful to life in my 20s, not partying as much , studying more, not staying alone as much, not waisting time. I'm doing my best now and keeping myself healthy , some people don't want to reverse aging, me it's a absolute yes. I would love to live life and experience all it has to offer in prime condition and with the knowledge and life lessons I learned over the time.

    • @P0Lak2012
      @P0Lak2012 Год назад

      Why

    • @Guidus125
      @Guidus125 Год назад +6

      @@jeffamg Interesting to hear you say you feel like you just recently started truly living, yet you felt that you partied too much when you were younger. I commonly hear people your age saying that partying is one of those things they actually didn't do, and that it's part of the reason they felt like they weren't really living. I guess moderation is key, and everyone ofc has their own thing to make them feel alive. In any case, the good thing is that you're only 38 (which I say as a 27 year old myself) , so statistically you have plenty of time left to live life the way you want it. If I may ask, is there a specific reason that you transformed your life recently? Perhaps a psychedelic awakening or something like that?

    • @6184aabbcdefg
      @6184aabbcdefg Год назад +2

      No you cannot be 21 again. But you could be better than that, dream bigger!

  • @rachelstark8002
    @rachelstark8002 2 года назад +10

    Even if most people don't believe longevity, they should still support it coz in fact we just have one life after all. Living up to a hundred and being still healthy is beyond priceless. I'm up for Dr. Sinclair's NMN supplementation. It's hard to prove something if you don't experience it yourself. Thanks to Vitruvin Health supplementation, I'll never have to worry about aging and the age-linked illnesses.

    • @diamondromeostewart8049
      @diamondromeostewart8049 Год назад

      Hello 👋 Rachel. How are you doing?

    • @lat6432
      @lat6432 Год назад

      @@diamondromeostewart8049 Do you know him?

    • @MyFirstHandle
      @MyFirstHandle Год назад

      Yeah, I know most people will never believe what David envisions, but I remain supportive on his ideas and other people who believes in longevity. I want to believe that I can live longer than expected.

    • @MichelleEinsteinSongBirdsong
      @MichelleEinsteinSongBirdsong 7 месяцев назад

      Where did you learn of Vitruvin? I never heard of it before.

  • @oliveaugustin6761
    @oliveaugustin6761 Год назад

    I was listening to your book. I got lost somewhere along! So here I am.

  • @fidalgoverde
    @fidalgoverde Год назад

    Stunning

  • @catherinekasmer9905
    @catherinekasmer9905 2 года назад +57

    The 22nd century will need to be about our existence not just as individual, separate organisms, but as collective organisms. We do not exist in a vacuum. The current Corona virus shows us this as does current research on the microbiome. Our living environment as well as our interconnected, interdependent existence with other humans and other species is key to survival. For example, our food depends upon plants that are supported by insects and bacteria. If those contributing causal factors of food production are damaged, so too will our survival be impacted. Our social interconnection matters as well. We exist in a world with tens of thousands of nuclear weapons that can do untold damage including destroying life on earth. Humbly I posit that surviving as a collective organism become our priority. We must hold our place as it were for a time in the future when we can have a peaceful planet that can safely support a smaller population that lives longer and healthier lives. If we can survive this current toxic episode in history we might be able to focus on long life. While a few elite people are at wonderful wealthy institutions such as Harvard, most people are getting inadequate education. It is hubris to think that the elite few with their exquisite research and their billions of dollars will save all us poor people. We need to consider the state of the collective organism now. Right now. For we are in a dangerous and precarious situation. Our oceans are trashed. Our air and water are polluted. Our ‘food’ supply is toxic. Most people are being ground into poor health with long hours of unsatisfactory labor. Our capitalistic system stands on the shoulders of field and factory labor which is exploitative. We are at war all over the planet. Your research is so beautiful. But I must say, unless we address the profound state of collective disease that exists today, what good will it be to stand alone at age 200 individually? Our social existence also has a profound impact on longevity as research shows- babies who are in isolation or deprived of human touch do not thrive. Our genetic existence tells a greater story. The story is that we exist collectively, interconnected and interdependent. Individual existence is a mirage. I sincerely hope this important work will be viewed in context. It is powerful, but without the broader context it will be rendered meaningless.

    • @Drew_Hurst
      @Drew_Hurst 2 года назад

      Yep

    • @margaretwong8707
      @margaretwong8707 2 года назад +1

      Agree with all said.
      If we all do our part, kind, generous, sharing & caring to our fellow humans, to all creatures and planet earth.
      Dr Sinclair is certainly doing his part in sharing what he knows, so clearly and so generously.

    • @MarkNOTW
      @MarkNOTW 2 года назад +1

      I think we should own nothing and be happy.

    • @JaMeXDDD
      @JaMeXDDD Год назад

      @@MarkNOTW So true Mark! That would be a true Utopia. Everyone owns everything and we are all equally mediocre.

  • @bnaiyer
    @bnaiyer Год назад +5

    Good talk to make us think. I have been using some modified amino-acid to achieve this successfully - Acetyl-L-Carnitine, Alpha-Lipoic Acid, N-Acetyl Cysteine. I am sure we will soon get such products to keep us young and healthy for many more years.

  • @milenadeltorto7158
    @milenadeltorto7158 2 года назад +1

    Go David go!

  • @fumikato
    @fumikato 8 месяцев назад

    my neighbor's newborn baby, was watching this before he went back into the womb. truly a reverse aging moment

  • @DeliaCrespo
    @DeliaCrespo 2 года назад +1

    Wonderfull David SInclair. Where can I get the rest this interview?

  • @dimitrichristou4889
    @dimitrichristou4889 Год назад +46

    I hear you about low calorie diets, reducing mTOR and lower protein. But look at the guy and others who eat this way. No muscle or strength. Longevity is also linked to muscle preservation. It’s a balance. I wouldn’t go this extreme personally. Eat your protein and lift the weights, but eat loads of veges and anti oxidants and fast for 16-20 hours a day. It’s not that hard

    • @BennyIncorporated
      @BennyIncorporated Год назад +16

      Dude the guy is spending his life researching basically inmortality, what time the dude has to be hitting weights.
      Having muscle mass and strength is not the only metric for health.
      And before you say anything, I also do intermediate fasting, hit the gym every day and all that shabang.

    • @dimitrichristou4889
      @dimitrichristou4889 Год назад +3

      @@BennyIncorporated I hear you dude. Each to their own preference 🙏🏼

    • @doggygaming950
      @doggygaming950 Год назад +2

      Did you not watch the video? He is talking about reversed aging and immortality.

    • @landoakechi9406
      @landoakechi9406 Год назад +3

      @@dimitrichristou4889 it's not about preference, he literally says antioxidants don't work

    • @tedallison6112
      @tedallison6112 Год назад

      There are 12 slices to the complete " fitness pie".
      Strength( albeit yr coveted muscles)is merely a small fraction of the whole.
      All surgeons & knowledgeable docs will gladly tell you that the cardio systems maintenance & development is paramount.
      ( cardiovascular, cardio-respitory & cardiopulmonary)
      That's why I run 12-15k daily( all slightly uphill) it builds strength & when coupled w an entirely organic diet, & 2 quarts of fresh made veggies & fruits juiced daily plus the cold therapy via Wim Hof well.....
      It works for me & is how I can play the hardest concert level classical piano compositions, run twice a day & play( run,karate,bike, gymnastics & swim) w my 8yr old son Thor( who is growing up & living up to his awesome name!!
      Remember: health is a choice,so is fitness& according to out esteemed lecturer, aging will also be a " choice".

  • @Ry_Tunes
    @Ry_Tunes Год назад +1

    Incredible science! Who would want to stick around in this place forever. I’m happy experiencing life and ageing gracefully and then RIP ✌️

    • @creativesource3514
      @creativesource3514 Год назад

      You can still do that but live healthy till 150.

    • @anynamez7048
      @anynamez7048 Год назад

      @@creativesource3514 how lol

    • @ten10_ten10
      @ten10_ten10 8 месяцев назад

      I would. That probably makes me a bit crazy, but I'd rather stay around for an infinite time. Of course, even if Sinclair does cure aging and death to an extent, we'll still have plenty of struggles to deal with such as the sun exploding and the heat death of the universe in a few billions of years. We should have a few billion years to solve that, if it's even possible. If not then guess I'll have no choice but at least I won't have to leave behind family or experience losing any of them since we'd all kinda die at the same time.
      (Also, so I don't sound too crazy, I know the chances of living to even a few thousand years right now are basically 0% but I can dream 🙃)

  • @newsmansuper2925
    @newsmansuper2925 Год назад

    great stuff

  • @evertonoliveira4924
    @evertonoliveira4924 Год назад +2

    Muito interessante esses resultados. Espero que os resultados sejam colhidos em breve.

  • @aaliyahlee1265
    @aaliyahlee1265 2 года назад +36

    I have been saying this... longevity is our choice! If we want to sustain our health, we have to do something about it! This will start by knowing what supplies our body needs. Start by eating a balanced diet, quit vices, exercise regularly and take an NMN supplement. Mine is a 500mg per day, NMN by Vitruvin. I just knew all of this lifespan information through Dr. Sinclair's book. It says there's no point increasing lifespan without. The goal should be to live longer while staying young and healthy. Sinclair believes that in the foreseeable future, it's possible for humans to live beyond 120 or even 150, without the frailty, diseases and disability we now associate with old age. See your result and tell the same experience.

    • @Ahmad-ww4ue
      @Ahmad-ww4ue 2 года назад

      Unfortunately, people like Elon Musk don't believe in longevity. He said it would be wrong to keep people alive for long periods of time. I felt that he secretly wants to die because he hates his crazy life as he once alluded to lmao.

    • @aaliyahlee1265
      @aaliyahlee1265 2 года назад

      @@Ahmad-ww4ue lol

    • @Tanya-ey4hj
      @Tanya-ey4hj 2 года назад +1

      What would be the benefit of your longer life span for this planet?

    • @aaliyahlee1265
      @aaliyahlee1265 2 года назад +8

      @@Tanya-ey4hj Why not... even if life is hard, if you're happy with you life, u will always choose to live longer 🙂

    • @diamondromeostewart8049
      @diamondromeostewart8049 Год назад

      Hello 👋 Aaliyah. How are you doing?

  • @ChrisBear1989
    @ChrisBear1989 Год назад

    Its really exciting.

  • @IsabellaRodriguezTechniqua
    @IsabellaRodriguezTechniqua 9 месяцев назад

    It breaks my heart to see how mice are used for scientific experiments, but I love the message and it helped me feel hopeful about science and the accuracy of how it is advancing.

  • @presleypryce6425
    @presleypryce6425 Год назад +2

    NAD changed my life… I have been receiving the therapy for several years. (since 2017) My doctor did a blood test and then kind of joked (but not really), you are getting younger, your methyl markers have reversed a bit…what are you doing?!?
    I replied, “NAD”.
    And for the record, I am now 34 and people think I am in my 20s. Don’t get me wrong, I also have a very healthy diet and do not consume refined sugars, stay away from dairy very little gluten. Sweating is a great detoxer! I Believe as a life and health coach student, that there are many facets of life that we need to focus on and change our lifestyle within to look AND feel our best.

    • @SeethingSimp
      @SeethingSimp Год назад

      Isn't having no sugar a joyless existence?

  • @sandtowalk
    @sandtowalk 2 года назад +4

    i have always known NAD was a key factor, great topic !

  • @lifeofheaven-co4fr
    @lifeofheaven-co4fr Год назад +1

    I think that genetic biology leads to his confidence and knowing

  • @madgoatspaddling
    @madgoatspaddling 2 года назад

    Very good!!!

  • @Acemanveryspecial
    @Acemanveryspecial Год назад +19

    I know he won't see this, but thank you David for trying to not only increase our health spans, but possibly solve the problem of aging.

    • @ThatBlueSkull
      @ThatBlueSkull Год назад +4

      Look up more of david sinclair if you see his interviews they already know how to reverse aging in mice he seemingly has solved the issue and now only waits human trials it seems

    • @Acemanveryspecial
      @Acemanveryspecial Год назад +7

      @@ThatBlueSkull I went back and watched a few of his old videos and he's always been very conservative with his predictions.
      The fact he's now exuding confidence in his work is very reassuring.

    • @TiernanRourke
      @TiernanRourke 3 месяца назад

      Sounds very interesting if mere ethics are in the way, could you provide a source to that statement?@@ThatBlueSkull

  • @josuel.9598
    @josuel.9598 Год назад +4

    Dude. If you look at a video from 9 years ago called "A Cure for Aging" (it's another tedx talk) He looks so much older! In this video He looks like he could be in his 30's. He literally changed between those 2 talks over the span of 9 yrs.

  • @healthanything8720
    @healthanything8720 Год назад

    Very powerful NMN!

  • @paulwood4142
    @paulwood4142 Год назад

    Genius man!

  • @yayangtapir4130
    @yayangtapir4130 2 года назад +20

    He is modern time god in true sense. May he keep up his awesome work. Waiting patiently for his next podcast. Please David come back soon.

    • @mickeytollison
      @mickeytollison Год назад

      No. Actually he is not.

    • @jazzhandsdan207
      @jazzhandsdan207 Год назад +1

      @@mickeytollison It’s just a figure of speech. Lol.
      If anything, at least he’s real.

  • @BBQsquirrel
    @BBQsquirrel 2 года назад +10

    This guy looks younger than he was when Veritasium interviewed him in 2019 so I think his research is legit.

    • @christiangrundmann6612
      @christiangrundmann6612 9 месяцев назад

      In 2020, he went from 2 meals a day to 1 meal a day. That's what made him look younger.

  • @EnligtenUs
    @EnligtenUs 4 месяца назад

    he's awesome.

  • @kisevetd6421
    @kisevetd6421 Год назад +1

    Great information! I want to get younger. I do fast and I feel awesome. I want to know more...

  • @angelusa73
    @angelusa73 2 года назад +36

    I think it's important not to live longer but BETTER.

  • @manuelojeda9144
    @manuelojeda9144 2 года назад +6

    I'm from the 1952 from Cuba. My greatgrandma lived to be 103 years old with no diseases.

  • @MauricioMassa
    @MauricioMassa Год назад +1

    Incredible!

  • @Gadinata
    @Gadinata 2 года назад +1

    Legend!