Exploring somatic mutations in cancer with COSMIC database and analysis tools

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  • Опубликовано: 29 сен 2024

Комментарии • 3

  • @lechhaveltizon9322
    @lechhaveltizon9322 Год назад +1

    Thank you for this!

  • @christyakachukwu2660
    @christyakachukwu2660 Год назад

    Thank you, I hardly see information on the Hypermethylation of a gene, does that mean that the gene is not inactivated my Hypermethylation

    • @EMBL-EBI
      @EMBL-EBI  Год назад

      Thanks for the comment, Christy.
      The visualisations on the current COSMIC website focus on somatic variants in coding regions. As methylation variants mainly map to regulatory regions these do not often appear in the Hyper/Hypo Methylation tracks on the main histogram (Gene View) on the Gene pages. However, by navigating to the 'Genome browser'
      section on the Gene page and switching on the 'Methylation' track, the methylation variants can be visualised.
      We hope that helps.