Well, let's see maybe if you and others like you are lucky, we will have this accurate enough in 15 years, then afterwards we just need to wait 30 more years for FDA approval because government is so fast don't you know.
But he did do it that young man who came on stage had a transplanted kidney from this Dr that was printed!!!! The technology seems to have fell away we should get ahold of this Dr
it's precisely because that it's already 2 years old that it would be quite fascinating to wonder about the status of this technology, especially with the growing commercial use for 3D printing! It's an exciting and inspiring video, and it can have the effect of making you feel good about being human (which, if you look around, isn't always the feeling you would get).
Amazing progress talk to a toddler actually I'm rather speechless and the story of the young man actually choked me up and brought tears to my eyes I worked in the human potential movement years ago as a counselor and I have to say there is apparently no limit to what you mean this kind of Chief as in the case of dr. Atallah I dictated these comments boy voice because of vision difficulties and I hope people can understand what I'm trying to say Doctor atala demonstrates that there is no limit apparently to what the human being can achieve
i wouldn't go that far yet , although bioengineering will take medicine to a whole new level and will improve and save alot of lives that need it we are not even close to be even dreaming about imortality , imagine for example what would go into printing or repairing a human brain which happens to be the most complicated thing known to man...
I'm really grateful for that disclaimer at 11:27. The speaker misleads the audience by calling it a "printed kidney" when really it's just the scaffold of a kidney. That's a massive difference.
@@Mo-sk7xo A natural organ, such as a kidney, is made up of a wide variety of cell types held together in the right shape by a biological meshwork called the extracellular matrix. You can see this matrix at 6:25 (which is naturally white after all the cells have been washed away). The meshwork is made up of a variety of non-living polymeric materials, which is handy for regenerative medicine scientists because we humans are already very good at manufacturing things from non-living polymeric materials such as plastics and resins and others. So creating an artificial meshwork of an organ, called a scaffold, is the easy bit (relatively speaking haha). On first watching, I assumed the kidney he shows at the end is just the scaffold (i.e. a printed artificial polymer which resembles the shape of a kidney down to the microscopic level) with no actual cells in it. I'd offer the analogy of building a city from scratch without putting any people in it; impressive, but functionless until you can find a way to get people (cells) inside. Cell types needed in solid organs are typically incapable of movement, so you'd either have to insert them into the scaffold whilst you're making it or find some clever way to perfuse the organ scaffold with those cells afterwards --- like they managed to with that piece of natural liver scaffold at 6:25. When I posted this last year, I didn't think it was possible to 3D print the scaffold at the same time as seeding the scaffold with cells. But upon rewatching this an some other videos, I realised that 3D printer ink sometimes use a mixture of scaffold materials and cells, letting the printed scaffold material solidify and polymerize around the cells. I'm surprised this works to be honest; it's a bit like pouring concrete with people in it! He doesn't explicitly say whether that prinetd kidney has cells or not, so I'm not sure. What I do know is it's been 8 years and printed kidneys still aren't viable yet. Sorry this was quite long, it's partly because I don't know your knowledge level on this subject, so please ask if you have any further questions of curiosities!
@@TheRABIDdude Nah you Pretty Much covered all my Questions lol...its Just I Wonder if They Printed certain Exterior Body parts how Would Pigment come Into Play?
@@Mo-sk7xo As in skin colour? I suppose they would have the same colouring as the patient because most of these techniques take the patient's own cells and multiply them in a petri dish before adding them to the replacement artificial organ --- like he described doing with that boy's bladder cells to coat the bladder scaffold they made artificially. Using a patient's own cells ensures a perfect tissue match, pretty much eliminating any chance that the patient's immune system rejects the new organ. The cells would be genetically the same as the rest on the body, and so you would expect them to have the same amount of pigment.
These things move so slow it's unbelievable. This video was made about seven years ago, another one was over ten years ago. I'm a paraplegic that needs a new bladder. I was injured at the age of three, I'm now 60. After being hit by a drunk driver my spinal cord was severed at T-10 complete. I have a neurogenic bladder that has also shrunk. Keeping all these things in mind I need a bladder replacement. Currently there are no studies being done. Even Wake Forest will not be continuing this work for another two years. Since I won't be able to go this route the bladder will have to be removed, my organs rerouted and a whole placed in my side for urinating in a bag. This will be for the rest of my life. Yet.....we have the technology. Why the waiting so long? will it be twenty or thirty more years before this will happen? If anyone hears of any studies please let me know!
A little torn on this one. I have chronic kidney disease and this is really great, but I also think we as humans are now way outliving the natural 'life span' of the species. It's great that we can live longer but can society really survive when people are spending 30-40 years retired?
society is nothing that is natural; tribe of 20-50 hunter gatherers is natural; society is a crazy experiment that we need to continue since invention of agriculture; the answer is to go on with biotechnology and AI and see what comes out of this
It's very complex and there are so many unknown factors that still have to be researched. This trial had 7 patients and all successes, but a later one by a different group had 10 patients and all failed. Also it can't be understated how fast moving the field is. The knowledge of how cells grow and change today is vastly expanded since 2006.
@@somethinghappened3721 Unfortunately, many medical scientists have become disillusioned with regenerative medicine and openly say that this is just scientific hype.
If why haven't things like this been implemented in today's technology every hospital should have one I am on permanent dialysis I could really use a new kidney but I can't get one because I'm an alcoholic and an addict This would be perfect for people like me That will never see a waiting list
Sure I imagine you already know about the octopus who can regrow an arm that is fully functional I've been bragging about you since I first heard the Ted talk about the arthritis and the bladder Sure you have truly made the world a better place for the human race thank you
i have seen this Ted video before but it was ages ago, did it get reupload for some reason or is it the same topic but with updated information about the advances in organ printing. Mhmmmm better watch some of it to answer my own questions :)
To create functional organ maybe the voltage sensitive liquid metal compound are best so it know what it is supposed to do and when does it need to do it ect
*Dr. Anthony Atala* already has done a *_Living Proof-of-Concept_* of this procedure by *transplanting* a *3D-printed* urinary bladder to a 9-year old kid, who eventually grew to become a *playing captain wrestler* of his senior high school. That was the year *1989.* Major advances are expected...
I'm glad that young man got his engineered bladder and things are working out. He will have a large outlook on life because of it and a large financial bill of debt he will carry with him too.
Could this mean the begin of immortality?If u think about it...u could literally print organs over and over again...then when u start aging and they start failing u simply place new ones.What do u guys think about this?
How can we get ahold of the young man who received the kidney? How can we connect with the Dr.? I know he is 65 and still-working in regenerative medicine. The 3D printer was not available then I believe
this is not a break trough if you looked more into science than just watching ted is that this has been around for a few years, whats a breakthrough is the higgs boson and NASA trying to make a warp engineering
Unfortunately, doctors from real practice, including those from respected medical institutions, told me that it is impossible to grow a real organ. All regenerative institutes are engaged in the getting of grants, not real science. No any real results last 15 years.
i'm with you, but remember what a scientific theory is. scientific theories are the most reliable, rigorously tested, and comprehensive forms of scientific knowledge. they come from hypotheses.
Probably they wait to post videos like this to gain some sort of perspective on how the research pans out,you wouldn't want something like this to flounder miserably...this or they didn't have a youtube channel 2 years ago and they're still catching up
People are trained to think intelligently, just like athletes are trained in strength and endurance. If you feel you are not currently smart enough to understand such things, all you need is intelligence training. -Think in First Principles -Be Objective -Use the Scientific Method -Use the Socratic Method -Be Thorough -Learn more Mathematics -Be Divergent -Look for efficient ways of doing things -Increase your sociability -Self Correct -Extrapolate -Look at things through different perspectives -Analyze all things Smart people don't do anything else outside of this list except stay focused, stay persistent, and work hard. And what they do on this list they do to varying degrees. So do everything and you'll be smart enough to study anything
So is that all that we have to do?Also do u think we could make like a human cyborg?Am thinking if we could print organs we could easily print an entire being!
How the hell did this not go viral?!?!?!
This is amazing!!!!!
My thought exactly when I saw the view count.
We All Know Why....Can't Get paid If you Solve the Problem....only if you Treat it
bc not enough people shared the video
Rip that project they failed
Because the US squashes anything that is progress
I know this is old, but it's still awesome. It is amazing how far medicine has gone in the past decade, let alone the past century.
Invest in medicine not weapons.
well, sadly there are still people who think they know it better and try to increase power by force. So weapons are necessary to protect scientist.
Alexander Lane don’t listen to him he’s In my class he’s just being funny
Weapons buys land thats responsible for your plants and chemicals that make your medicine bro
yah it's hyphotheses
Invest in CURES, not BIG pharma!!!
Thanks to these kind of Doctors. Hoping it to come faster to people.
As a 33 year old in Kidney Failure and on dialysis, sure would be nice if they'd move these along already.
They make a ton of money on dialysis unfortunately.
Well, let's see maybe if you and others like you are lucky, we will have this accurate enough in 15 years, then afterwards we just need to wait 30 more years for FDA approval because government is so fast don't you know.
agreed I need one of those
But he did do it that young man who came on stage had a transplanted kidney from this Dr that was printed!!!! The technology seems to have fell away we should get ahold of this Dr
That's what I was saying
It's been about 12-15 years l hear about this technology, but we're always 5 years from it.
Amazing, we can see so many scientific breakthrough in 21st century, glad to see all this unfolding. I'm just mind-blown.
it's precisely because that it's already 2 years old that it would be quite fascinating to wonder about the status of this technology, especially with the growing commercial use for 3D printing! It's an exciting and inspiring video, and it can have the effect of making you feel good about being human (which, if you look around, isn't always the feeling you would get).
*11 years old
15:10 I can't be the only one who felt "saved my life." Choking back a tear...
Amazing progress talk to a toddler actually I'm rather speechless and the story of the young man actually choked me up and brought tears to my eyes
I worked in the human potential movement years ago as a counselor and I have to say there is apparently no limit to what you mean this kind of Chief as in the case of dr. Atallah
I dictated these comments boy voice because of vision difficulties and I hope people can understand what I'm trying to say
Doctor atala demonstrates that there is no limit apparently to what the human being can achieve
Bravo! This is absolutely a great and important medical breaktrough.
I saw this 2 years ago on the main TED channel?
No matter, still one of THE BEST TED talks.
A lot of respect.
i wouldn't go that far yet , although bioengineering will take medicine to a whole new level and will improve and save alot of lives that need it we are not even close to be even dreaming about imortality , imagine for example what would go into printing or repairing a human brain which happens to be the most complicated thing known to man...
I'm really grateful for that disclaimer at 11:27. The speaker misleads the audience by calling it a "printed kidney" when really it's just the scaffold of a kidney. That's a massive difference.
Whats the Difference? not being douchy
@@Mo-sk7xo A natural organ, such as a kidney, is made up of a wide variety of cell types held together in the right shape by a biological meshwork called the extracellular matrix. You can see this matrix at 6:25 (which is naturally white after all the cells have been washed away). The meshwork is made up of a variety of non-living polymeric materials, which is handy for regenerative medicine scientists because we humans are already very good at manufacturing things from non-living polymeric materials such as plastics and resins and others. So creating an artificial meshwork of an organ, called a scaffold, is the easy bit (relatively speaking haha).
On first watching, I assumed the kidney he shows at the end is just the scaffold (i.e. a printed artificial polymer which resembles the shape of a kidney down to the microscopic level) with no actual cells in it. I'd offer the analogy of building a city from scratch without putting any people in it; impressive, but functionless until you can find a way to get people (cells) inside. Cell types needed in solid organs are typically incapable of movement, so you'd either have to insert them into the scaffold whilst you're making it or find some clever way to perfuse the organ scaffold with those cells afterwards --- like they managed to with that piece of natural liver scaffold at 6:25.
When I posted this last year, I didn't think it was possible to 3D print the scaffold at the same time as seeding the scaffold with cells. But upon rewatching this an some other videos, I realised that 3D printer ink sometimes use a mixture of scaffold materials and cells, letting the printed scaffold material solidify and polymerize around the cells. I'm surprised this works to be honest; it's a bit like pouring concrete with people in it! He doesn't explicitly say whether that prinetd kidney has cells or not, so I'm not sure. What I do know is it's been 8 years and printed kidneys still aren't viable yet.
Sorry this was quite long, it's partly because I don't know your knowledge level on this subject, so please ask if you have any further questions of curiosities!
@@TheRABIDdude Nah you Pretty Much covered all my Questions lol...its Just I Wonder if They Printed certain Exterior Body parts how Would Pigment come Into Play?
@@Mo-sk7xo As in skin colour? I suppose they would have the same colouring as the patient because most of these techniques take the patient's own cells and multiply them in a petri dish before adding them to the replacement artificial organ --- like he described doing with that boy's bladder cells to coat the bladder scaffold they made artificially. Using a patient's own cells ensures a perfect tissue match, pretty much eliminating any chance that the patient's immune system rejects the new organ. The cells would be genetically the same as the rest on the body, and so you would expect them to have the same amount of pigment.
@@TheRABIDdude pretty detailed :) thanks
This talk happened in 2011. Decade later this dream remains as dream.
Exactly. And looks like it will never been. It doesnt work.
That's what I was saying
It's been about 12-15 years l hear about this technology, but we're always 5 years behind from it.
These things move so slow it's unbelievable. This video was made about seven years ago, another one was over ten years ago. I'm a paraplegic that needs a new bladder. I was injured at the age of three, I'm now 60. After being hit by a drunk driver my spinal cord was severed at T-10 complete. I have a neurogenic bladder that has also shrunk. Keeping all these things in mind I need a bladder replacement. Currently there are no studies being done. Even Wake Forest will not be continuing this work for another two years. Since I won't be able to go this route the bladder will have to be removed, my organs rerouted and a whole placed in my side for urinating in a bag. This will be for the rest of my life. Yet.....we have the technology. Why the waiting so long? will it be twenty or thirty more years before this will happen? If anyone hears of any studies please let me know!
I am definitely curious to know more about , the trials and the results ... :) BEAUTIFUL :)
A little torn on this one. I have chronic kidney disease and this is really great, but I also think we as humans are now way outliving the natural 'life span' of the species. It's great that we can live longer but can society really survive when people are spending 30-40 years retired?
society is nothing that is natural; tribe of 20-50 hunter gatherers is natural; society is a crazy experiment that we need to continue since invention of agriculture; the answer is to go on with biotechnology and AI and see what comes out of this
I was just watching this talk for my 3D printing essay and now it's on TEDed! Don't tell me the internet isn't psychic.
A decade after the video was uploaded and the technologie is still impressive
Anthony Atala is awesome!
This sounds amazing. But I hasn't heard much about this technology after almost 10 years. Any thoughts why?
Looks like it doesn't work...
@@user-zl6hq2ki1c Unfortunately (( Or maybe some forces do not need this technology working...
It's very complex and there are so many unknown factors that still have to be researched. This trial had 7 patients and all successes, but a later one by a different group had 10 patients and all failed. Also it can't be understated how fast moving the field is. The knowledge of how cells grow and change today is vastly expanded since 2006.
@@somethinghappened3721 Unfortunately, many medical scientists have become disillusioned with regenerative medicine and openly say that this is just scientific hype.
So why is it not available yet?
Dayumn! Ground breaking technology! Great work!!!!
If why haven't things like this been implemented in today's technology every hospital should have one I am on permanent dialysis I could really use a new kidney but I can't get one because I'm an alcoholic and an addict This would be perfect for people like me That will never see a waiting list
Then why don't you try get help alcoholism and addiction? Also, why are you on dialysis? What's your syndrome if you wouldn't mind me asking?
Sure I imagine you already know about the octopus who can regrow an arm that is fully functional
I've been bragging about you since I first heard the Ted talk about the arthritis and the bladder
Sure you have truly made the world a better place for the human race thank you
Bravo to all the humans making a positive difference in the world
i have seen this Ted video before but it was ages ago, did it get reupload for some reason or is it the same topic but with updated information about the advances in organ printing.
Mhmmmm better watch some of it to answer my own questions :)
That's the future I've been waiting for.
To create functional organ maybe the voltage sensitive liquid metal compound are best so it know what it is supposed to do and when does it need to do it ect
now this feels like the future
this is mind blowing!
Watching In 2021 hope they got it working
Sorry but no... It is impossible...
I am proud that a Peruvian doctor has achieved such a feat.
Seven years later, imagine all the organs we're able to print today.
Yea i know but hopes we need to put pressure on our governments to sponsor regenerative medicine and anti aging therapies
That's what I was saying
It's been about 12-15 years l hear about this technology, but we're always 5 years behind from it.
I haven't seen it before. I only watched the Nova scienceNow episode "Can we live forever" a few months back that features the same technology.
Brilliant!
awesome!
by the time I need a kidney my iphone will just print while i sleep and then install it before breakfast hooray
Brilliant technology. Can't wait to see this stuff hit the market in a few years and change the lives of chronically ill people forever.
wow.. thats pretty amazing!
maybe they need to increase or decrease vibrational charges when trying to grow liver cells
Brilliant stuff.
I wonder how it is now.
Edit: He kinda reminds me of Mark Ruffalo tbh. Especially in 13:30
You are actually, very correct.
*Dr. Anthony Atala* already has done a *_Living Proof-of-Concept_* of this procedure by *transplanting* a *3D-printed* urinary bladder to a 9-year old kid, who eventually grew to become a *playing captain wrestler* of his senior high school.
That was the year *1989.*
Major advances are expected...
1999 I thought
It is a great work!!! how can I access to get this treatment?
I'm glad that young man got his engineered bladder and things are working out. He will have a large outlook on life because of it and a large financial bill of debt he will carry with him too.
tony has transplanted a kiney or bladder????
13:35 - 14:00 its funny how he says thank you. this guy is awsome
andito ako dahil sa biology ko na assignment
That is amazing, and kind of creepy but amazing
Could this mean the begin of immortality?If u think about it...u could literally print organs over and over again...then when u start aging and they start failing u simply place new ones.What do u guys think about this?
If they take the cell from your body, the cell still have your DNA, and this DNA still getting shorter and losing it's function as you get older.
This video was made ten years ago, what progress has been made since then? How close is a 3D printed kidney ready for transplant surgery?
great work!
Some people use headphones and they don't like to have their eardrums popped.
7 years Later and we still cant print kidneys :/
Actually we have but a smaller version called organoids. It not like the said here but in different way.
How can we get ahold of the young man who received the kidney? How can we connect with the Dr.? I know he is 65 and still-working in regenerative medicine. The 3D printer was not available then I believe
A real American and Pioneer 👍
Thank you!
Yes
This would be cooler if my school wasn’t making me do work with it
this is not a break trough if you looked more into science than just watching ted is that this has been around for a few years, whats a breakthrough is the higgs boson and NASA trying to make a warp engineering
This is amazing!!!
10years later .... wow
8:15 holy shit! starship troopers moment! that scene where the main character in the pool with some machine healing his leg?
Medical Science is reaching unbelievable heights
Fantastic! Dr. Anthony Atala should get a Nobel Prize for this. We Filipinos appreciate the milestones that Dr Atala has made.
he said 2011... so this video is 2 years old, why upload it now?
Unfortunately, doctors from real practice, including those from respected medical institutions, told me that it is impossible to grow a real organ. All regenerative institutes are engaged in the getting of grants, not real science. No any real results last 15 years.
i'm with you, but remember what a scientific theory is. scientific theories are the most reliable, rigorously tested, and comprehensive forms of scientific knowledge. they come from hypotheses.
Technology has come far, but where is the access for people to get it. People are still on many organ lists. 🤷🏽♂️
12.00 'who wants a feel?' *throws into audience*
Any updates on this?
Probably they wait to post videos like this to gain some sort of perspective on how the research pans out,you wouldn't want something like this to flounder miserably...this or they didn't have a youtube channel 2 years ago and they're still catching up
I knew you were going to say that.
Amazing video! A standing ovation that he completely deserved! Despite being an atheist I want to say say *"God bless you people"*
But why this is the only case happing in the world up to now???? This is posted nearly twelve years ago.
Hello sir
we have used to ionic-liqued for ink of 3D printer ???
so amazing!!! I wish I was smart enough to study that :(
Yessi villa you are
People are trained to think intelligently, just like athletes are trained in strength and endurance.
If you feel you are not currently smart enough to understand such things, all you need is intelligence training.
-Think in First Principles
-Be Objective
-Use the Scientific Method
-Use the Socratic Method
-Be Thorough
-Learn more Mathematics
-Be Divergent
-Look for efficient ways of doing things
-Increase your sociability
-Self Correct
-Extrapolate
-Look at things through different perspectives
-Analyze all things
Smart people don't do anything else outside of this list except stay focused, stay persistent, and work hard. And what they do on this list they do to varying degrees.
So do everything and you'll be smart enough to study anything
intelligence is trained, not acquired
Science rocks the world!
YES
It's not what you want, but it's what you need.. *Batman voice*
yes.
yes
if luke m got the kidney in 2013 then why isn't this kidney still commercialised? when will this be available for common ppl...
He got a bladder not a kidney
Count how many times this guy says actually, you will actually be here for a long time
8:40 I could swear I was watching something out of The Fifth Element.
Who can answer this for me. this TED ed was in 2013. What is the status this technology in 2023. I am a kidney patient.
So is that all that we have to do?Also do u think we could make like a human cyborg?Am thinking if we could print organs we could easily print an entire being!
I hope it would help the patients soon with all god's grace
this amazing:D
So he can 3D print a organ that looks like a squeezy toy and doesn't function? What is the point if it doesn't work or function?
if its the first time you watch ted no. If its the 500th one you watch you see the benefit of it.
Who else is watching this is quarantine for school
What has happened?
Not all heroes wear capes....
rowan atkinson ??
Am I the only one who has seen this talk already? on this channel? on youtube?
Still under development?