Glutamate Modulation | MOA Animation
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- Опубликовано: 11 мар 2020
- xvivo.com/examples/glutamate-...
Glutamate is the most abundant excitatory neurotransmitter in the brain. Release of glutamate is essential for normal function of neurons, but the levels of this neurotransmitter must be tightly regulated to avoid toxic effects on neurons.
XVIVO partnered with Biohaven to animate the glutamate story. The script details normal glutamate signaling, dysfunctional glutamate signaling and the mechanism of action of Biohaven’s investigational agent trigriluzole, a novel neuroprotective agent to modulate glutamate neurotransmission. Trigriluzole is expected to reduce the neurotoxicity associated with excessive glutamatergic excitation, which is implicated in many disorders involving the central nervous system. 
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Wow! This is magical!
Watching this as part of revision for my master in psychiatry exam and this made me fully understand Glutamate synthesis. Thank you!
Love it when you add the narration!
These are incredible, thank you
10/10 animation and narration
this is unique!...just beautiful!
This is great! Thank you so much
Best channel in youtube ♥️ thanks
Great explanation 😍
Thank you)
Love the music.
Oh this a banger
Well done
may I use this video and combine it with other videos as educational material for my students?
how did you make that solution/??/?
Does anyone know how mutations of the SOD-1 gene tie into this?
What is the relationship between glutathione and glutimate? Is glutathione supplementation contraindicated with neurotoxicity? How do we clear glutimate?
How to we avoid it?
in layman's terms - is glutamate released when someone eats foods containing Mono-sodium-glutamate? And, would you say that people who are "Sensitive" to MSG that produces these high concentrations susceptible to developing diseases like mentioned above? Or, is it the other way around? I have dissociative disorder and my current symptoms mimic times in the past when I have noticeably ingested foods that contain MSG. The symptoms are similar. Brain-fog, confusion... all kinds of symptoms. Are you saying these are related? I just want to know if there is a way to connect the physiological effects of excess glutamate in the brain, with the physiological affects of dissociative disorder with the every day act of eating something containing ingredients that boost glutamate in the body/brain. Is there a connection?? This video mentions central nervous system responses. "Glutamatergic Excitation" I guess I'd like to see if there is more information about the connection between this and the central nervous system and disorders of the central nervous system. Did I develop Dissociation symptoms later in life because of my predisposition to be sensitive to excess glutamate or did early childhood trauma make my brain predisposition to experiencing excess glutamate in the brain. I'm not sure if I'm making sense. Maybe you have more resources for me or an extra explanation? Thanks in advance, loved the video.
Hey, you can get glutamate from food like MSG, but in reality, glutamate is produced in your body anyway, in the body's central nervous system from Glutamine. Glutamine is an amino acid that comes from your diet as well, and is also produced in the body, in muscles. MSG in culinary terms, is simply an additive, just like how you can also add extra sugar to food products, but there are foods that naturally contain sugar too. Some food that naturally contains high glutamate levels include seafood, tomatoes, some cheeses and processed meats, plus others.
If you think you are sensitive to glutamate, you can reduce your intake from diet by looking for low glutamate foods.
As for your dissociative disorder, I am not a psychologist nor a doctor (I study biomed), but some studies have linked consumption of glutamate with more psychiatric distress, this is not so surprising since glutamate is a neurotransmitter. You should ask a qualified neurologist.
@@Stefunny19 that was so kind of you to reply so eloquently, love when people are this helpful. And I learned something.
Thank u
So sad I cannot up this video to 1080p nor just to 480p. But WHY❔💔
Is this drug available yet?
🤩👏🏻
CLOSED CAPTION PLS
It's there, just click the button in the bottom right corner.
@@Stefunny19 thanks,it's now available,,,,, initially it was not there
How to reduce Glutamate?
Lithium orotate, nac, agmatine...
Taurine and magnesium both play a key role in managing glutamate
Plz add subtitle next time 🙈💔
Subtitles are available, just click the icon in the bottom right.
En español
BDNF looks like a dinosaur