I Swear, I could kiss you man. You got me through Immunology as an undergrad and now I'm on my PhD and still watching your videos for guidance. Thank you so much!
Winner of a video, I been tryin to find out about "hypersecretion" for a while now, and I think this has helped. Ever heard of - Yannabarn Vanish Thyroid - (do a search on google ) ? Ive heard some incredible things about it and my m8 got cool success with it.
@@owais6162 In some culture kissing a man on the chick is not gay... Moreover you don't know if he is or not ! Not to mention that being gay is not a shame or what :)
Mr. Hasudungan, I commented a while back in one of your newest videos about how I didn’t like the fact that now you weren’t doing hand drawings. Now, in this 2012 video I see how much effort and quality you have put into your videos. It really touched me to see how you colored that entire big arrow with those thin markers. I haven’t checked out if you have released new videos but regardless of the method, I am grateful for your channel and I really thank you for the time you devote to making these videos.
Love your videos!!! I watch them to help me prepare for practicals and exams, they're perfect for integrating all the information from my textbook. I just wanted to note that T3&T4 are amino acid derived hormones, not lipid. Thanks!!
Armando thank you for these classes. I was a second year med student when i started to watch your videos and now i am a resident( soon will be consultant) and still watching you. You are a legend!
Hey Armando, I've been using your videos to study various parts of human physiology for quite some time. Today I find that on my University website, our Endocrinology module has a link to your videos - the link even mentions you by name!
*Don’t expect to hear this from your doctor, but following the right hypothyroidism diet plan is by far the biggest factor in overcoming hypothyroidism. You can do everything else right and be using the best available supplements or medication, but if your diet isn’t right, then you will be forever fighting a battle that you just can’t win*.Learn more here-> plus.google.com/109849515216441135952/posts/Z5tTgFix6w7
Armando, you have been a lifesaver during my first undergrad in Physiology, and now for my second one in Medicine. Thank you for making concepts look so easy and fun. I can literally watch a video of yours once and it sticks :)
I once learned an entire semester of calculus from an amazing tutor. Now, Armando, you are doing this again for me in AandP. Thank you for your diligent studying and hard work so you can pass the knowledge on. So grateful
your video taught me more than my stupid textbook ever dreamed of! i actually said "oh!" multiple times while watching. i love all your videos and i geek out on your art. please keep up the awesomeness!
Hey, Possibly there is some controversy with this, but what I know, and the sources I use state that pendrin is a IODIDE transporter, and therefore Iodide has to be in the colloid for conversion. It states that "On the lumenal side of the apical membrane Iodide is oxidized" Werner & Ingbar's The Thyroid: A Fundamental and Clinical Text.
Can you explain what happens when too much fluoride / fluorine gets involved here? Seems like it'd potentially react over iodide at least some of the time
There are TWO iodine transporter 1. Sodium Iodide Symporter- seen in "basolateral membrane" of follicular cells which helps entry of iodine from circulation into follicular cells 2. Iodide - Chloride exchanger called Pendrin - Seen in "Apical Surface" of thyroid follicular cells helping iodide into colloid Oxidising happens in "Apical Membrane" of thyroid follicular cells Basically what you said is correct Source - Harrison Internal Medicine 20th edition
Very cool, but a few comments. TRH receptor is coupled to a Gq protein in the tyrotroph cell, and TSH receptor is coupled to a Gs protein in the follicular cell membrane. Another detail is that the negative feedback acts directly and indirectly: by directly inhibiting the production of TSH by the tyrotroph and indirectly diminishing the production of TRH receptors on the surface of tyrotroph cells. Last, but not least, when the iodine attaches to de 5,3‘,5‘ carbons or 3,3‘,5‘ carbons, it is called “reverseT3“ (rT3) and has no biologic activity, T3 has only biologic activity if the iodine is in the 3 and 5 carbons (regardless if it is attached to 3‘ or 5‘ carbon). Very useful video, congrats.
I am thanking God for randomly reaching in your channel...no words . it's beyond words...thank you soooo much..just by a single video..I get addicted to your teaching
Amazing! My daughter was born without a Thyroid! No doctor/Endocrinologist has ever tried to go into any real details about her condition. Only that we have to do blood work often and regulate her medication through the TSH Blood work/Lab test but I am learning that there is more to it than just T3 and Synthetic Drugs. I feel overwhelmed but I am trying to learn more about all of this and to give my daughter the best life that we can make for her to feel better. Thank you so much!
I am a visual learner and found this video really helpful in putting all the steps together for the thyroid gland. Helped alot for my lecture in pharmacy school for human anatomy and physiology. Thanks.
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
He said it is basically a lipid when it reaches the blood stream for transport because thyroxine binds with plasma proteins which makes it lipid soluble and passes thru membrane easily
All your videos are great, they are my first point of call when I have a new subject to learn... Is there any chance you could upload the posters you draw; it would be great to pin them up on my wall... thank you for the videos your passion for teaching is very evident!
Deviprasad Boggupalli true... we can only state it as lipophilic hormones which are able to cross the plasma membrane and cause an action within the cell.
+btingang That is true, but it seems like they don't even cross the plasma membrane, but instead require a transporter despite being lipophilic: press.endocrine.org/doi/abs/10.1210/edrv.22.4.0435
Dude , I Am A 5th Year Med Student In Egypt & Ur Vids Help Me Alot Especially In Internal Medicine , Here Are Some Topics That Will Help If U Explaimed ThemnThe Way You Do , Hepatitis , Hepatic Encephalopthy , Portal Hypertension . . . Please Man :D
hey sir ( regard as my teacher ) i am a doctor preparing for MRCOG part 1 and now studying basic science with your help. thanks alot for your work. keep going man.
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
i am a pakistani student .. having physiology as a subject.. your videos are great.. i was always confused in physiology but ur videos leads me to the right way.. now i understand it very clearly
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Excellent explanation on thyroid. Wish I had seen this prior to Radio Active treatment (X2) which destroyed my thyroid. Lifelong user of synthetic T3 and T4.
Wow, Armando you are brilliant! Thank you so much for this video, you did a wonderful job explaining the process. I honestly feel like your technique of explaining and sketching was easier to understand than some upscale 3D video (which is totally what I was looking for ha-ha). I love the simplistic Sharpie colors, your exquisite hand writing; and love that you've managed to combine science with art - in my world, most science minded individuals can't draw.
I have my Molecular Endocrinology Final tomorrow, and I must say, this makes the facts super clear. Loved the fact that you went into the molecular basis of it. Thank you very much!
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Thanks ever so much for these vids. ... I'm a super visual learner & this format is so much more efficient for me than anything else I've come across. ... and I spent years in special ed classes learning to mediate my learning disabilities, so that's kind of saying something. 😁👍
Great job Armando Hasudungan! Without your very well explained and animated video, It was boring for me to read and understand Guyton book. Thanks a million times;)
I watched this because of my hypothyroidism that I was diagnosed with 9 years ago, and because I am a Biological Sciences undergrad I thoroughly enjoyed and understood watching this. I now understand my chronic condition better so thanks ^.^
Hey Armando thank you for everything you taught us here for free. I am now an Internist because I really understood the several concepts in Medicine because of your Videos. Thank you so so much!
At the end of the video, I think it would help if you zoomed out so we can see the entire picture once you finish.. These drawings and diagrams are amazing and SUPER helpful! Obviously this is an old video but that is my only suggestion!
I Swear, I could kiss you man.
You got me through Immunology as an undergrad and now I'm on my PhD and still watching your videos for guidance. Thank you so much!
he is not a gay though
😂😂
Winner of a video, I been tryin to find out about "hypersecretion" for a while now, and I think this has helped. Ever heard of - Yannabarn Vanish Thyroid - (do a search on google ) ? Ive heard some incredible things about it and my m8 got cool success with it.
@@owais6162 In some culture kissing a man on the chick is not gay...
Moreover you don't know if he is or not ! Not to mention that being gay is not a shame or what :)
@@jermhondr dude it was a joke, i did not even mention that being a gay is a shame you brought that up not me
An eleven year old video explained to me a better concept that is too detailed , then the newly uploaded ones . Thankyou so much 🐝
Mr. Hasudungan,
I commented a while back in one of your newest videos about how I didn’t like the fact that now you weren’t doing hand drawings. Now, in this 2012 video I see how much effort and quality you have put into your videos. It really touched me to see how you colored that entire big arrow with those thin markers. I haven’t checked out if you have released new videos but regardless of the method, I am grateful for your channel and I really thank you for the time you devote to making these videos.
If what this man does doesn't count as charity, I don't know what will. Thank you so much.
All thanks to dr moses on youtube for curing from hyperthyroidism...
Love your videos!!! I watch them to help me prepare for practicals and exams, they're perfect for integrating all the information from my textbook. I just wanted to note that T3&T4 are amino acid derived hormones, not lipid. Thanks!!
Brilliant.. No words..my finals start tomorrow and your videos are so helpful. Please continue them.I need them a lot
your explanations are 100X better than those in my university
Armando thank you for these classes. I was a second year med student when i started to watch your videos and now i am a resident( soon will be consultant) and still watching you. You are a legend!
Hey Armando, I've been using your videos to study various parts of human physiology for quite some time. Today I find that on my University website, our Endocrinology module has a link to your videos - the link even mentions you by name!
Abominatrix650 :)
Sebastian Zimmermann Your spam is not wanted or needed. Please leave.
Man, thank you very much !! If I pass my exam I will buy you a beer or two if we someday meet by chance :D
*Don’t expect to hear this from your doctor, but following the right hypothyroidism diet plan is by far the biggest factor in overcoming hypothyroidism. You can do everything else right and be using the best available supplements or medication, but if your diet isn’t right, then you will be forever fighting a battle that you just can’t win*.Learn more here-> plus.google.com/109849515216441135952/posts/Z5tTgFix6w7
@@violettemartin2757 No.
it been 10years and this video still helps....God bless you man
Armando, you have been a lifesaver during my first undergrad in Physiology, and now for my second one in Medicine. Thank you for making concepts look so easy and fun. I can literally watch a video of yours once and it sticks :)
Permanently cured with Dr iyaremoses medicine on RUclips channel name #driyaremoses
I once learned an entire semester of calculus from an amazing tutor. Now, Armando, you are doing this again for me in AandP. Thank you for your diligent studying and hard work so you can pass the knowledge on. So grateful
your video taught me more than my stupid textbook ever dreamed of! i actually said "oh!" multiple times while watching. i love all your videos and i geek out on your art. please keep up the awesomeness!
Are you kidding me?. This guy deserves a 1 million subscribers why isn’t he there yet
Hey,
Possibly there is some controversy with this, but what I know, and the sources I use state that pendrin is a IODIDE transporter, and therefore Iodide has to be in the colloid for conversion. It states that "On the lumenal side of the apical membrane Iodide is oxidized"
Werner & Ingbar's The Thyroid: A Fundamental and Clinical Text.
Can you explain what happens when too much fluoride / fluorine gets involved here? Seems like it'd potentially react over iodide at least some of the time
There are TWO iodine transporter
1. Sodium Iodide Symporter- seen in "basolateral membrane" of follicular cells which helps entry of iodine from circulation into follicular cells
2. Iodide - Chloride exchanger called Pendrin - Seen in "Apical Surface" of thyroid follicular cells helping iodide into colloid
Oxidising happens in "Apical Membrane" of thyroid follicular cells
Basically what you said is correct
Source - Harrison Internal Medicine 20th edition
Very cool, but a few comments.
TRH receptor is coupled to a Gq protein in the tyrotroph cell, and TSH receptor is coupled to a Gs protein in the follicular cell membrane.
Another detail is that the negative feedback acts directly and indirectly: by directly inhibiting the production of TSH by the tyrotroph and indirectly diminishing the production of TRH receptors on the surface of tyrotroph cells.
Last, but not least, when the iodine attaches to de 5,3‘,5‘ carbons or 3,3‘,5‘ carbons, it is called “reverseT3“ (rT3) and has no biologic activity, T3 has only biologic activity if the iodine is in the 3 and 5 carbons (regardless if it is attached to 3‘ or 5‘ carbon).
Very useful video, congrats.
TRH is the hormone released by the hypothalamus, and TSH is the hormone released by the anterior pituitary gland, in the thyrotropic cells
...Obviously...
Ur words r exactly as I read in my book...BRS physio..
Thank you so much. T3 and T4 were just floating in my head and this is just what I needed!!
I am thanking God for randomly reaching in your channel...no words . it's beyond words...thank you soooo much..just by a single video..I get addicted to your teaching
Absolutely excellent! I missed the lecture on this topic but this follows our notes super closely. Thank you.
Amazing! My daughter was born without a Thyroid! No doctor/Endocrinologist has ever tried to go into any real details about her condition. Only that we have to do blood work often and regulate her medication through the TSH Blood work/Lab test but I am learning that there is more to it than just T3 and Synthetic Drugs. I feel overwhelmed but I am trying to learn more about all of this and to give my daughter the best life that we can make for her to feel better. Thank you so much!
This is such a great resource for visual learners like myself. Keep up the great work!
Thank You❤
I am a student at KAU and this guy is actually pretty helpful, he got me through most modules and I gladly recommend him.
Wonderful Wonderful! I am almost out of PreClinical because of you! Merci!
I'm obsessed with this content. Thank you
Thank you for your work, such a great help with my studies.
I am a visual learner and found this video really helpful in putting all the steps together for the thyroid gland. Helped alot for my lecture in pharmacy school for human anatomy and physiology. Thanks.
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
lovely video, really appreciate it. Since its a learning platform, thyroxine is an amino acid derived protein not lipid. Thanks.
He said it is basically a lipid when it reaches the blood stream for transport because thyroxine binds with plasma proteins which makes it lipid soluble and passes thru membrane easily
No text book can beat you, you are THE BEST. Thank you for what you do
All your videos are great, they are my first point of call when I have a new subject to learn... Is there any chance you could upload the posters you draw; it would be great to pin them up on my wall... thank you for the videos your passion for teaching is very evident!
his posters are available for sale on his website
This was the best video of the thyroid system I've seen. Explains everything clearly.
Words can not describe your talent
Thanks
I am a big fan:) :) :) :)
Well done, Armando. That was the best explanation of thyroid hormone synthesis I have EVER heard. You're my angel.
Oh armando, i love you for the rest of my medical life 😂
🤭Though I never saw him but still 😂I have a crush on him.
It's been a year since I discovered your channel and followed. Your videos have taught me so much that I know now. I love your art too, keep it on.
All thanks to dr iyaremoses on youtube for curing from hyperthyroidism
Beautifully explained, thank you!
You are incredible!! MD student and you are ten times better than my lectures in a quarter of the time!
Thanks a mill ! , if only our teacher explained things like this.
I can only pray for you , thank you for everything bro
I find this video amazing because I was actually born with out the thyroid gland. I have to depend of levothyroxine to do all the work.
U r diong great 🤗
Wow
Respect you so much...
A good physician, good artist, good biochemist, good presenter, good teacher... you nail it!
All thanks to dr iyaremoses on youtube for curing from hyperthyroidism
I am so grateful ♡
Your videos have helped me so much for Veterinary School topics! Thank you and please keep at it!
Dude your sh*t is the bomb! Keep up the excellent work!
thank you! thank you! thank you! you made this so easy to understand, engaging, and not a 30 minute long video. subscribed!
All thanks to dr moses on youtube for curing from hyperthyroidism.
HI your videos are really helpful, but I don't think we can mention thyroid hormones as lipid hormones since they are derived from amino acid Tyr.
Deviprasad Boggupalli true... we can only state it as lipophilic hormones which are able to cross the plasma membrane and cause an action within the cell.
+btingang That is true, but it seems like they don't even cross the plasma membrane, but instead require a transporter despite being lipophilic: press.endocrine.org/doi/abs/10.1210/edrv.22.4.0435
Yeah that's what I thought. think he means lipophilic.
lipophilic means it doesn't like lipids. So how can't it be a lipid hormone? It is an Amine.
If i am not wrong, philic is to like?!
Thank you for these videos; as a 2nd year medical student, your videos really help clarify things.
Dude , I Am A 5th Year Med Student In Egypt & Ur Vids Help Me Alot Especially In Internal Medicine , Here Are Some Topics That Will Help If U Explaimed ThemnThe Way You Do , Hepatitis , Hepatic Encephalopthy , Portal Hypertension . . . Please Man :D
Omar El-Sobky hey man i have videos on most of the topics u mentioned. I hope u can find them!
+Armando Hasudungan u r just awesome... thanks a lot for ur videos they help me a lot....
Omar El-Sobky زمانك اتخرجت حالا😂😂😂😞ربنا يوفق
lolz med :'(
hey sir ( regard as my teacher ) i am a doctor preparing for MRCOG part 1 and now studying basic science with your help. thanks alot for your work. keep going man.
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Best Prof. Ever ^_^ ...
Keep on ...
better than my professor , you made my night thank you for sharing it for free on you tube.
AMMMMMMMMMMMMAZZZZZZZZZZZZZZING thank youuuu veeeeery muchhhhhhhh geniussssss
omer ibrahim Iu
i am a pakistani student .. having physiology as a subject.. your videos are great.. i was always confused in physiology but ur videos leads me to the right way.. now i understand it very clearly
you say that T4 and T3 are lipids towards the end. they are not lipids as they are amino acid derived. do you mean lipophilic?
Anjani Kammili I think yes
yes they are lipid soluble hormone (an amine but lipid soluble ) he is right 😊
he is right they are steroid/lipid hormones
yeah lipophilic
The way you make such topics easy is phenomenal 😊
All thanks to dr moses on youtube for curing from hyperthyroidism
Is your source Guyton's Medical Physiology? :)
+Micah Perry Plot Twist: He IS Guyton....
*Dun Dun DUNNN*
@@termite1012 🤣
Ur videos are such a help for last minute study especially during exams
do u have dyslexia? i notice u interchange letters
dugadug Mybaguio.biz most likely
best video on thyroid hormones, hands down
you make things look so easy ..even when they are not ..thank you so much
Amazing yrrrr......finally I get a video from which I can understand well and prepare myself for exams...
Amazing teacher! Such clarity, reinforcement and fluent visual stimuli . Thank you!!
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Your videos are helping me immensely in medical school. The illustrations and explanations are fantastic!! Thank you so much!
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
This videos are so clear, so easy to follow and so helpful. Thank you
This is the most helpful video. Thank you so much for making this. Very helpful for veterinary school!
Your videos are amazing! I am a surgical trainee and we have to cover physiology and your videos ARE SAVING ME. Thank you!!!
this is great, the way you show all the steps in the thyroid synthesis thank you
such amazing videos! Where were these when I was in med school! Thank YOU!!
Brilliantly comprehensive with concise explanations. Keep it up!
All thanks to dr moses on youtube for curing from hyperthyroidism.
This is a life saver.
I wasn't able to understand this whole process from books...
This is just Wow!
I love your videos! I am a visual learner and your videos are amazing. God bless you!!
Thank you so much! Your videos are so helpful to me as a visual learner. I love the way you connect everything as well.
Thank you for your fantastic video explaining the Thyroid Gland and Thyroid Hormones.
probably mentioned already but TRH is thyrotropin-releasing hormone not thyroid releasing hormone...love your videos, they are a great help!
simple yur writing and drawing is amazing
Excellent explanation on thyroid. Wish I had seen this prior to Radio Active treatment (X2) which destroyed my thyroid. Lifelong user of synthetic T3 and T4.
Wow, Armando you are brilliant! Thank you so much for this video, you did a wonderful job explaining the process. I honestly feel like your technique of explaining and sketching was easier to understand than some upscale 3D video (which is totally what I was looking for ha-ha). I love the simplistic Sharpie colors, your exquisite hand writing; and love that you've managed to combine science with art - in my world, most science minded individuals can't draw.
I have my Molecular Endocrinology Final tomorrow, and I must say, this makes the facts super clear. Loved the fact that you went into the molecular basis of it. Thank you very much!
Writing from Canada I have had a lot about Dr iyaremoses on RUclips channel herbs medication that it has helped a lot of people get rid of hypothyroidism in just 21days
Amando - impressive piece of work. Bravo!
I enjoyed watching your informative, creative video. This was the most descriptive presentation on RUclips of Thyroid hormones. Cheers!
Videos are very helpful to understand difficult topics. Keep it up.
Thanks ever so much for these vids. ... I'm a super visual learner & this format is so much more efficient for me than anything else I've come across. ... and I spent years in special ed classes learning to mediate my learning disabilities, so that's kind of saying something. 😁👍
Dude these videos give me a clear perspective on life!! thank you for sharing your skill and knowledge!
Please continue what u are doing u are a great help to everybody who are reviewing for their board exams 💕
All thanks to dr moses on youtube for curing from hyperthyroidism...
Great job Armando Hasudungan! Without your very well explained and animated video, It was boring for me to read and understand Guyton book. Thanks a million times;)
THANKS FOR PROVIDING SUCH A GREAT KNOWLEDGE
I hope u have an idea how great of a work u r doing armando
Thank you for support
You're right. William's Textbook of Endocrinology also states that TPO (thyroid peroxidase) is a protein located in the apical membrane. Thanks!
THANKS A LOT FOR THE VALUABLE TIME U SPARED FOR MAKING THIS VIDEO.ITS EXCELLENT
I watched this because of my hypothyroidism that I was diagnosed with 9 years ago, and because I am a Biological Sciences undergrad I thoroughly enjoyed and understood watching this. I now understand my chronic condition better so thanks ^.^
Thank u very much mister , your videos are so helpful, I can't find words to describe how amazing your way of teaching is ! ... 🌷
Hey Armando thank you for everything you taught us here for free. I am now an Internist because I really understood the several concepts in Medicine because of your Videos. Thank you so so much!
Permanently cured with Dr iyaremoses medicine on RUclips channel name #driyaremoses
Fantastic! The explanations, the drawings..everything. Great job!
Thank you very much. This video was very helpful. Your drawings are good and you explained the basics really well.
Fantastic presentation! Great illustration.
Your video are really really helpful for preparing my admission test. Thank you so so much Armando☺️🙏🏻
Permanently cured with Dr iyaremoses medicine on RUclips channel name #driyaremoses
Really hats off to your dedication to teaching sir ,really awesome easily understood 😊😊
You are indeed a life saver. Thank you so much for all your videos
At the end of the video, I think it would help if you zoomed out so we can see the entire picture once you finish.. These drawings and diagrams are amazing and SUPER helpful! Obviously this is an old video but that is my only suggestion!
You' ve really helped me a lot！just want to say thank you, cause with your videos in these 2 years, I'm passing all the exams graduating！