Once again the man delivers! You certainly put a magnifying glass and expound on it where textbooks and standard learning tools just gloss over it. Thank you very much Ninja Nerd
A Young man, who really knows his subject, I am a therapist, and live to study this stuff, but, this guy is incredible, what a brain he has, live people like him who know their subject.
Zach you are making me go to medical school..... as a genomics scientist and ever wanting to learn, I am so happy to have found your incredible lectures!!! Simply the best!
How many times are you going to win the only heart I have. This guy is really a god gift for medical students around the globe. Huge Respect and love from Germany :)
I just survived thyroid storm, I'm still at home recovering from it, after being the hospital for a long time... enjoying watching your videos so I can understand this better.. I had no idea I even had a overactive thyroid and I go to docs , they just never tested it..
You are a life saver! The way my lecturers explained it never seemed to make sense to me. The way you go through the whole process step by step is super helpful. Now I now how to T4 and T3 are synthesised and I'm confident for my exam. Thank you!
I’m relatively new on this channel and I’m finding it a terrific resource in learning the things I need to know. I have Panhypopituitarism, have had it for over twenty years but I’m still learning all of the factors involved in maintaining one’s life when one’s pituitary gland is basically nonexistent. Thank you so much for helping me to understand as much as possible regarding my medical plight! Best regards from Kathryn Featherston 😊🎓☺️🧠
This is pure gold - Read my physiology book and didn´t understand much - untill i watched this video. Now the books is easily understood! Thank you very much - and please - please - never stop making these videos!
This video was AMAZING. My professor's notes are so scattered, we never know where he stops one section and begins the next. THANK YOU for putting this together so well!!!
oh my god, you are AMAZING. I'm new to your channel. I am currently studying endocrinology for my physiology class, and you are a lifesaver! My prof's notes are so vague, and he talks so fast during lectures that it is hard to write down all the extra information he says to clarify the notes. But your videos, really help to fill in those missing gaps that are in the notes my prof posted. I am officially not scared of my final exam anymore. I subscribed. Thank you so much, you have made my day!!
This video is so amazing!! You go into all the wonderful details without making it overwhelming. I’m currently reviewing for my vet school finals and this was pure perfection.
Dear Dr Zach, your teaching styles are so awesome! I’d already wacthed entire of Biochemistry, Microbiology, İmmunology, Cell Biology sections, and currently on in Physology. You and your team doing a great job! Keep going on!
Literally every topic I start I come here for your video’s, reading alone I can’t absorb but I watch your videos and it all clicks into place, thank you for helping me pass my degree, I don’t think I could do it without you💓
My mind is blown on how scientists have actually studied this not to mention the 500 kazillion other things in our body. You are a really intelligent guy. Geesh
The numbered recap at the end was super helpful in organizing the main bullet points. Thanks for all your amazing work! Because of you, medical school isn't just about memorizing anymore. You're the man! Also I saw you wear some UH gear in one of your videos, go Warriors!!
Thank you for these videos. You don't know how many times your videos actually saved me from flunking my previous semester, I have seen your videos from biochemistry up to here. Thank you for your hard work! Sincerely, A Struggling Med Student.
~You are amazing...getting your point across in the simplest way possible....YOU should or maybe you already are an instructor....thank you sooooo-much for everything young man. Teaching is your gift.
I have a small correction for a very small mistake in the video After the cleavage of T4 and T3 from thyroglobulin, T4 and T3 won't have a vesicle around them, because they actually lipid soluble, so they will just diffuse from the thyroglobulin vesicle (which is made primarily from lipid) to the cytosol, then they will diffuse also through the cell membrane to the bloodstream. Thanks so much for your videos they are really helpful.
Sir, I am a fan of your teaching...You explain complex things so simply it's amazing...Thanks for making these videos, please make more of these videos.
@ Ninja Nerd Science, during coupling process of iodothyronine residues @ 16:15.. MIT+DIT is a reverse T3 of which is biologically inactive. The only Active T3 (Triiodothyronine) coupling residues is DIT+MIT. Thank You.
![Thyroid Hormone Synthesis: Step-By-Step Pathway [Physiology Explained]](http://i.ytimg.com/vi/1Dgz9Pky6WA/mqdefault.jpg)
18 dislikes are the school professors who are losing students to this guy... Your work is incredible man.
Fax😏
🤣🤣
🤣🤣
Fact🤣🤣
Totally agree 🤣🤣🤣🤣 koz I don't watch anyone else...not even my own professors
you've helped so many med students become doctors
Soo damn truee!!!!!!!
Nurses too 😂🎉
It's true
PAs too!
Pharmacist too!
when he explained t3 and t4 my head exploded. I literally yelled. I think all this studying is getting to me.
Me too!
You are right, that was my first time to understand that part of thyroid physiology. Wonderful Teacher!!!
Your ability to read complicated info, understand it, remember it and then explain it so well is beyond imaginable!!!! Amazing
Table of Contents
0:00 Intro - Hypothalamic-Hypophyseal System.
3:46 - TSH Effects & Thyroglobulin Synthesis.
7:30 - Thyroglobulin and Iodide/Iodine.
12:10 - Iodination Process.
14:18 - Formation of T4 and T3.
19:26 - Transportation of thyroid hormones.
20:50 - Recap.
Great
As in a book?
not all herroes wear capes
Thanks
THANKS!!!!!!!!!!!!!!!
please please do this for all his videos!!!
Once again the man delivers! You certainly put a magnifying glass and expound on it where textbooks and standard learning tools just gloss over it. Thank you very much Ninja Nerd
+Reynaldo PersonalEmail we are so happy to help! I am so glad that these videos are helping! It is our goal to help in anyway possible!
Endocrinology used to be my least favorite part of physiology until I watched your videos. Thank you for everything!!
Do you know if a thyroid issue could be mistaken as diabetes? Type1.. some of the symptoms seem to be about the same for both.
OMG SAME! After learning from these, I topped my class
@@NanditaJali i want to quit
@@aryan7767 you wanna talk about it?
@@NanditaJali im so sorry for concerning you. no its my own laziness pls ignore me haha
A Young man, who really knows his subject, I am a therapist, and live to study this stuff, but, this guy is incredible, what a brain he has, live people like him who know their subject.
Sorry for spelling, phone.
Zach you are making me go to medical school..... as a genomics scientist and ever wanting to learn, I am so happy to have found your incredible lectures!!!
Simply the best!
honestly can't emphasize enough how much I appreciate your work
Seriously, you do not understand how many times you've saved me and I'm only halfway through my degree....
L
How many times are you going to win the only heart I have. This guy is really a god gift for medical students around the globe. Huge Respect and love from Germany :)
Your videos are PHENOMENAL! You've got a great teaching style, keep the videos coming!
You are seriously the BEST to ever exist and to ever TEACH, not one university professor compares. Lots of love!!!!!🙌🏽
"T peroxidase kicks iodine so hard it knocks an electron out of him" lol that's a good way to remember it
He is an amazing teacher genius
Lmao yesss
Dude, thats literally the golden commentary ever
🤣🤣🤣
😂😂😂😂😂😂😂
I just survived thyroid storm, I'm still at home recovering from it, after being the hospital for a long time... enjoying watching your videos so I can understand this better.. I had no idea I even had a overactive thyroid and I go to docs , they just never tested it..
My sir taught me this 3 times but still i used to forget this concept and you taught me only once and now i remember forever 🙏 Thankyou
Much love and respect to you. Thank you. I feel like crying right now because you explained it so well!
Nerd ninja you are God to Indian medical students
Big love from India !!
I personally want to meet you some day sir
I guess 10 millions gods werent enough for yall
@@med8615 yet following any gods would give the same vision! : Do justice nd u'll get the same !
I get it you apreciate him hes really good at wht he does but he doesnt replace god and he is not a god he is just human
God is there with in every creature
Usama N
A man with a name OSAMA shouldn’t talk about god atleast😂
Thank you so much for taking dry, complicated subjects and bringing them to life so that they are understandable! I'm so glad I found your channel!
For those wondering what the Transcription Factor protein is at 5:04 , its Thyroid Specific Transcription Factor-1 (TTF-1)
my GOD!!you have no idea how much i love you! you always save my grades!! good job and i hope you never stop teaching us!!
This guy is just unique in his explanations. He is a professor of the age! No match yet!!
You are a life saver! The way my lecturers explained it never seemed to make sense to me. The way you go through the whole process step by step is super helpful. Now I now how to T4 and T3 are synthesised and I'm confident for my exam. Thank you!
I’m relatively new on this channel and I’m finding it a terrific resource in learning the things I need to know. I have Panhypopituitarism, have had it for over twenty years but I’m still learning all of the factors involved in maintaining one’s life when one’s pituitary gland is basically nonexistent. Thank you so much for helping me to understand as much as possible regarding my medical plight! Best regards from Kathryn Featherston 😊🎓☺️🧠
This is pure gold - Read my physiology book and didn´t understand much - untill i watched this video. Now the books is easily understood!
Thank you very much - and please - please - never stop making these videos!
This video was AMAZING. My professor's notes are so scattered, we never know where he stops one section and begins the next. THANK YOU for putting this together so well!!!
trueeeeee
Sir, you deserve a medal of honor. I'm screaming thank you!!!!
You are the best medicine teacher in the world! I'm a med student from China. You are my superman!!!🥰😍😍
currently in an accelerated program and your 30 minute lesson is 10000000x better than the doctor's 3 hr lecture.
Exactly
This man explained his topic passionately with humility. Thank you so much for creating good techniques. 👏
so good thank you ....saving my life as a pharmacy student.. honestly professors do not even explain they just sent a crap ppt and called it a day
oh my god, you are AMAZING. I'm new to your channel. I am currently studying endocrinology for my physiology class, and you are a lifesaver! My prof's notes are so vague, and he talks so fast during lectures that it is hard to write down all the extra information he says to clarify the notes. But your videos, really help to fill in those missing gaps that are in the notes my prof posted. I am officially not scared of my final exam anymore. I subscribed. Thank you so much, you have made my day!!
BIG thanks from iraq 🇮🇶 you really help me in my post graduate medical career , keep going on dear and may God bless you dear.
انشالله تخرجتي ؟
This video is so amazing!! You go into all the wonderful details without making it overwhelming. I’m currently reviewing for my vet school finals and this was pure perfection.
Pharmacy student here, great video thanks for the help Ninja Nerds.
Dear Dr Zach, your teaching styles are so awesome! I’d already wacthed entire of Biochemistry, Microbiology, İmmunology, Cell Biology sections, and currently on in Physology. You and your team doing a great job! Keep going on!
Every time I watch a video of this guy, I thank God for making me learn English (I'm from Brazil)
Literally every topic I start I come here for your video’s, reading alone I can’t absorb but I watch your videos and it all clicks into place, thank you for helping me pass my degree, I don’t think I could do it without you💓
You seriously deserve so much more credit then you are given! I love your videos please don't stop making them lol
My mind is blown on how scientists have actually studied this not to mention the 500 kazillion other things in our body. You are a really intelligent guy. Geesh
Tanks from algeria eventhough our médical studies are done with french language
Your lessons are much better realy you are a great men
The numbered recap at the end was super helpful in organizing the main bullet points. Thanks for all your amazing work! Because of you, medical school isn't just about memorizing anymore. You're the man! Also I saw you wear some UH gear in one of your videos, go Warriors!!
The most amazing RUclips video I've seen all year. Thankyou for producing it. It's most helpful in explaining and incredibly complex.
Nerd Ninja you're absolutely a blessing to Med students . Fan here from Papua New Guinea 🇵🇬
If not you some of us would have really failed to become good doctors, you really doing a great job!!!
Thanks Zach,u are helping millions of mbbs students to get graduated easily.
15:33 I literally gasped 😲
Understanding T3 & T4 🤓
Thank you ☺
Me too! Not where I was expecting things to go. So cool!!
i just understood it within 10 min after watching THIS my whole conception got cleared
thank you for sticking through the whole process of making this video
I have no words how to appreciate your effort.Really mind blowing Sir.Thank You so Much.
You deserve an award for helping many medical students 🙌🏻 excellent
you are so power brooooooo!!! this video is very very helpful ! i'm so glad that i found it .
Thank you so much! And if you could share with friends that would be appreciated!
I repeated the video twice to stuck the information ,huge thinks for your effort 💜💜الله يجزاك خيررر
props for the camera guy who always follows your movements! love u guys
Sir, you my respect. I hope your personal life and character are as excellent as your teaching ability and knowledge. Good work
Thank you for these videos. You don't know how many times your videos actually saved me from flunking my previous semester, I have seen your videos from biochemistry up to here. Thank you for your hard work!
Sincerely,
A Struggling Med Student.
You have alot in the ball ...I can't get over how much your vedioes are helping me ...
~You are amazing...getting your point across in the simplest way possible....YOU should or maybe you already are an instructor....thank you sooooo-much for everything young man. Teaching is your gift.
This makes studying Pharmacology easy! I'm currently cramming for a big presentation and don't know what I would do without your videos.
You are my BEST teacher. The greatest ever. Thank you
You are certainly teh best teacher of Biology... I always get here when something irks :) God Bless You
I have a small correction for a very small mistake in the video
After the cleavage of T4 and T3 from thyroglobulin, T4 and T3 won't have a vesicle around them, because they actually lipid soluble, so they will just diffuse from the thyroglobulin vesicle (which is made primarily from lipid) to the cytosol, then they will diffuse also through the cell membrane to the bloodstream.
Thanks so much for your videos they are really helpful.
You make learning so fun, you make learning all those steps not hard to love
Iodide stored in thyroid gland in the form of
A-Thyroglobulin
B-Diiodothroxine
C-Monoiodothyroixin
D-Tetra iodothroxin
E-Triiodothyroxine
The smile that lit up my face when it all made sense. What a beautiful romance between T3 & T4, I guess the T.P.O is the matchmaker.
I have Panhypopituitarism. I've always seen T4 on my bloodwork but never knew what it really meant. This video was incredibly informative!
When you came to the coupling part, I died, this is gold. THANK YOU!
I feel like, I am in heaven when I am listening to your lectures
Don't stop teaching please huhu I love your methods of putting things to perspective. Superb. Thank you
Thank you so much sir........you did help me to score the highest marks ❤️❤️❤️❤️
My continued survival of med school is dependent on these videos. Thank you
When I say, that I love you...I really mean it....I literally hate my physiology HOD who keeps so many test......but ur video..I love you professor
Man I wish RUclips and this guy was available when I went to nursing school in 2011…
Sir, I am a fan of your teaching...You explain complex things so simply it's amazing...Thanks for making these videos, please make more of these videos.
I can listen to these discussions all day even i don't remember anything
I am starting to love endocrinology because of you. Thank you so much!!!!
i cannot believe how amazing this is! Thank you Sir! Incredible work!!
I wish my textbooks were this clear and concise
Second year med student here, this guy knows his stuff!!!!!
Your explanation is incredible man...I need you in my college😢 .. all respect to you❤❤
I just discover this channel and I am so grateful for this quality content and those brilliant mind ! Thank you !
You are really the coolest teacher ever. Thanks for making medicine so much fun. So much love and best wishes.
Sir.... actually you are the world's best teacher i had ever seen....thank you sooo much sir❤lots of love from india 🇮🇳
Absolutely awesome man... Huge respect for you man the way you teach is just amazing..... Lots of love to you from India🇮🇳
Wow, you are amazingly smart. Thank you for teaching this. You make it so much easier to understand
What an amazing lecture! Thank you so much Ninja Nerd ❤ You help me a lot
you made that complicated mechanism perfectly EASY! Thank you
My students have told me about your lectures today. Wow this is inspiring!
I’m not done with the video yet, I had to pause to thank you. God bless you
was so confused by my lectures but this is so clear and I'm actually interested!! thank you so much cant wait to watch more in the future!
@ Ninja Nerd Science, during coupling process of iodothyronine residues @ 16:15.. MIT+DIT is a reverse T3 of which is biologically inactive. The only Active T3 (Triiodothyronine) coupling residues is DIT+MIT. Thank You.
DIT can bind to MIT or DIT, but can you get MIT binding with another MIT? T2 hormone?
Best Channel for physiology ever❤
excellent video...u forgot to mention endocytosis of colloid is done by megalin protien...
I love your videos!! I appreciate them so much!! Thank you so much !! YOU ARE SAVING MY LIFE !!
Thank You Zach! Thank You Ninja Nerd Science!
Bro is literally gods gift to medicine
The french guy- TPO is my new favorite
This was very satisfying to watch to re-run-through in a more focused break-down
U r amazing...very talented smart guy..lots of love n blessings to you from Nepal 👍🙏