Heart of the Matter - Carcinoid Syndrome and Carcinoid Heart Disease

Carcinoid syndrome (CS) is uncommon, however, it is the hormonal syndrome most commonly experienced by those with certain functioning NETs (primarily, but not exclusively, small bowel) and is defined by chronic diarrhoea / flushing in the presence of elevated levels of serotonin [or its metabolite 5-hydroxyindolacetic acid (5-HIAA)].
Atypical carcinoid syndrome (ACS) may be experienced by those with NETs originating in the lung, stomach, duodenum / ovary. ACS is characterised by a patchy, intensely red, flush, sweating, itching, wheezing, salivary gland swelling, eye-watering (lacrimation) and cardiovascular instability e.g., hypo/hypertension (low/high blood pressure).
Carcinoid heart disease (CHD, Hedinger syndrome), is a rare condition that affects about one in five (20%) patients who have both neuroendocrine cancer AND carcinoid syndrome (CS).
In this webinar, hosted by Neuroendocrine Cancer UK, Wendy & Mike Martin (Kings Healthcare Partners ENETs Centre of Excellence) talk about Carcinoid Syndrome - with a particular focus on Carcinoid Heart Disease. Wendy is the senior Clinical Nurse Specialist for Neuroendocrine Cancer, and Mike, is the senior Peri-operative Specialist Practitioner, in Cardio-thoracics, at Kings.
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What about with someone who is bicuspid and has G3 NET/NEC?