How to perform Weighted gene co-expression network analysis (WGCNA) without coding?

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  • Опубликовано: 4 ноя 2024

Комментарии • 57

  • @Nature520-k6i
    @Nature520-k6i 6 месяцев назад +1

    This is really amazing and easy explanation. I will do this type of analysis in near future. and refer to your video

    • @asifmolbio
      @asifmolbio  6 месяцев назад

      Glad if it’s helping

  • @samkhan7536
    @samkhan7536 Год назад +1

    Very informative lecture

  • @Paachi8651
    @Paachi8651 2 месяца назад +1

    Sir,where s ur institute, want to come and learn especially R,python,WGCNA, Deseq2,Roc, PCA .Practical ly i want to learn ,m doing phd in bioinformatics without nothing,Can u pls help me .

    • @asifmolbio
      @asifmolbio  2 месяца назад

      I am based in china at present. One to one session can be booked: if needed go to about section on RUclips channel and fill the form

    • @Paachi8651
      @Paachi8651 2 месяца назад +1

      Where will I get the link and fill the form ji

    • @asifmolbio
      @asifmolbio  2 месяца назад

      www.youtube.com/@asifmolbio/about

  • @tanusreedatta4493
    @tanusreedatta4493 15 дней назад +1

    Hello brother, is it only for Arabidopsis or I can use other plant ids?

    • @asifmolbio
      @asifmolbio  15 дней назад

      Any specie is okay

    • @tanusreedatta4493
      @tanusreedatta4493 15 дней назад

      @asifmolbio Okay Thank you. Here you have mentioned that, it is applicable for 15 samples. Samples means control and treatment plant numbers? Or something else! Cause I have one control and 2 treatments. Can I do WGCNA with these?

    • @asifmolbio
      @asifmolbio  15 дней назад

      @@tanusreedatta4493 total including control, treatment and replicates should be more than 15

    • @tanusreedatta4493
      @tanusreedatta4493 15 дней назад +1

      @asifmolbio Okay got it. Your videos are too helpful brother. I watch your videos and the explanation is better than other videos. I am in Zhengzhou University, Henan, China, doing PhD with Agriculture field. Could you please share your wechat?

    • @tanusreedatta4493
      @tanusreedatta4493 14 дней назад

      @asifmolbio Thank you brother

  • @prashanthjavali4182
    @prashanthjavali4182 10 месяцев назад +1

    Hi sir this is very usefull video , My question is if i have microarray data specially expression profiling by array and i want to perform WGNCA analysis can i able to performe with idep server ? If yes kindly help me on this

    • @asifmolbio
      @asifmolbio  10 месяцев назад

      Yes, you can

    • @prashanthjavali4182
      @prashanthjavali4182 10 месяцев назад +1

      @@asifmolbio sir how to do that sir can u please explain me

    • @asifmolbio
      @asifmolbio  10 месяцев назад

      upload your expression file in excel similar to i have done in this video

    • @prashanthjavali4182
      @prashanthjavali4182 10 месяцев назад +1

      @@asifmolbio only expression file is enough ???? no need of design file??

    • @asifmolbio
      @asifmolbio  10 месяцев назад

      let me send you a design file video

  • @sakibsarkerii514
    @sakibsarkerii514 5 месяцев назад

    Sir, I have been following your videos from last one year. I have learned a lot of things from your videos. Sir, can u make a video about how to apply WGCNA in microarray dataset using R? Please sir, I will be very grateful if you make a video on this topic. I have been trying to perform WGCNA in GSE62232 but I am failing.

    • @asifmolbio
      @asifmolbio  5 месяцев назад +1

      Thank Sakib, Sure i have noted down your topic, i will make a video soon inshaAlllah.

    • @sakibsarkerii514
      @sakibsarkerii514 5 месяцев назад +1

      @@asifmolbio Thank you so much sir.

    • @sakibsarkerii514
      @sakibsarkerii514 4 месяца назад

      ​@@asifmolbio sir can we expect the video near future? Plz sir

  • @taramin873
    @taramin873 10 месяцев назад

    Thanks for sharing this video you kinda saved me
    I still have question, what is the edge threshold
    thank you^^^^^^^

    • @asifmolbio
      @asifmolbio  10 месяцев назад

      Welcome you can start by setting it to 0.5 as a starting point.

  • @sanjuktaghosh8802
    @sanjuktaghosh8802 9 месяцев назад

    Hi Dr Asif. You said atleast 15 samples. So, is it total 15 samples taking all groups or each group should have 15 samples? Also do you have a video where you have prepared the gene count file from RNA-Seq sample data?

    • @asifmolbio
      @asifmolbio  9 месяцев назад

      All the samples from all groups should be more than 15, not from one group

    • @asifmolbio
      @asifmolbio  9 месяцев назад

      How to calculate FC, log2FC, Pvalue, Padj, Up/down genes in RNA seq data using Excel
      ruclips.net/video/HH3Mll4W5WE/видео.html

  • @taramin873
    @taramin873 10 месяцев назад

    one more question 🙋 which step can I set the p.value to 0.05? THANK YOU^^

    • @asifmolbio
      @asifmolbio  10 месяцев назад

      In the iDEP tool

    • @asifmolbio
      @asifmolbio  10 месяцев назад

      In the start of analysis

  • @mdsymunrabby7625
    @mdsymunrabby7625 Год назад +2

    How do I get the Design file of the specific gene ID?

    • @asifmolbio
      @asifmolbio  Год назад

      Need to create by yourself see the video on my channel to learn

  • @nikhilchand5329
    @nikhilchand5329 Год назад +1

    I am performing iDEP with gene ids of wheat.
    But on loading data in iDEP it shows disconnected from the server. Please provide any suggestion to resolve the problem.

    • @asifmolbio
      @asifmolbio  Год назад

      I never faced any problem like this. Probably website will be under maintenance you can try after a day or two.

    • @nikhilchand5329
      @nikhilchand5329 Год назад +1

      @@asifmolbio Okk sir
      Any alternative to do WGCNA

    • @asifmolbio
      @asifmolbio  Год назад

      Alternative is through R programming. But i am sure, website will be functional. You can try after changing internet or computer

    • @nikhilchand5329
      @nikhilchand5329 Год назад

      @@asifmolbio okk sir

    • @kumaka6
      @kumaka6 Год назад +1

      check your input data whether it is in correct format. may i know how many samples you have given as input.

  • @subhankarraha4033
    @subhankarraha4033 8 месяцев назад

    Dear sir, i want to verify some genes of my interest are co-expressed or not via this iDEP tool. Is it possible, is their any need of special R coding
    If I want to check specific genes are responsible for specific hormonal pathway. can I do it via this iDEP tool? ( If the RNA SEQ data is not available in iDEV itself)
    Thank you in advanced

    • @asifmolbio
      @asifmolbio  8 месяцев назад

      There is no tool to verify to find genes co expressing.
      You need to look your pathway by yourself from all pathways
      Watch this video to get an idea

    • @asifmolbio
      @asifmolbio  8 месяцев назад

      How to select genes for qPCR validation in transcriptome/RNA seq data?
      ruclips.net/video/PRhHBcjKAKU/видео.html

  • @nikhilchand5329
    @nikhilchand5329 Год назад

    Good afternoon sir
    I am using list of wheat gene ids with TraesCS4D02G203800 but iDEP showing error I'd not recognised.
    What I have to do sir?

    • @asifmolbio
      @asifmolbio  Год назад

      Can you change the gene and try any other id ? Still same

  • @sreeram6416
    @sreeram6416 6 часов назад +1

    design file is the metadata file know sir

    • @asifmolbio
      @asifmolbio  3 часа назад

      Design file is for choosing treatments comparisons

  • @RjAtifAyub
    @RjAtifAyub Год назад

    If sample size is less then 15 then what we should do?

    • @asifmolbio
      @asifmolbio  Год назад

      Then authentication of wgcna can be questionable to some extent.